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Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk
Author / Creator:Das Pradhan, Aruna ; Glynn, Robert J. ; Fruchart, Jean-Charles ; MacFadyen, Jean G. ; Zaharris, Elaine S. ; Everett, Brendan M. ; Campbell, Stuart E. ; Oshima, Ryu ; Amarenco, Pierre ; Blom, Dirk J. ; Brinton, Eliot A. ; Eckel, Robert H. ; Elam, Marshall B. ; Felicio, João S. ; Ginsberg, Henry N. ; Goudev, Assen ; Ishibashi, Shun ; Joseph, Jacob ; Kodama, Tatsuhiko ; Koenig, Wolfgang ; Leiter, Lawrence A. ; Lorenzatti, Alberto J. ; Mankovsky, Boris ; Marx, Nikolaus ; Nordestgaard, Børge G. ; Páll, Dénes ; Ray, Kausik K. ; Santos, Raul D. ; Soran, Handrean ; Susekov, Andrey ; Tendera, Michal ; Yokote, Koutaro ; Paynter, Nina P. ; Buring, Julie E. ; Libby, Peter ; Ridker, Paul M
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2022-11, Vol.387 (21), p.1923-1934
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Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome
Author / Creator:Witztum, Joseph L ; Gaudet, Daniel ; Freedman, Steven D ; Alexander, Veronica J ; Digenio, Andres ; Williams, Karren R ; Yang, Qingqing ; Hughes, Steven G ; Geary, Richard S ; Arca, Marcello ; Stroes, Erik S.G ; Bergeron, Jean ; Soran, Handrean ; Civeira, Fernando ; Hemphill, Linda ; Tsimikas, Sotirios ; Blom, Dirk J ; O’Dea, Louis ; Bruckert, Eric
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-08, Vol.381 (6), p.531-542
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Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease
Author / Creator:Crosby, Jacy ; Peloso, Gina M ; Auer, Paul L ; Crosslin, David R ; Stitziel, Nathan O ; Lange, Leslie A ; Lu, Yingchang ; Tang, Zheng-zheng ; Zhang, He ; Hindy, George ; Masca, Nicholas ; Stirrups, Kathleen ; Kanoni, Stavroula ; Do, Ron ; Jun, Goo ; Hu, Youna ; Kang, Hyun Min ; Xue, Chenyi ; Goel, Anuj ; Farrall, Martin ; Duga, Stefano ; Merlini, Pier Angelica ; Asselta, Rosanna ; Girelli, Domenico ; Olivieri, Oliviero ; Martinelli, Nicola ; Yin, Wu ; Reilly, Dermot ; Speliotes, Elizabeth ; Fox, Caroline S ; Hveem, Kristian ; Holmen, Oddgeir L ; Nikpay, Majid ; Farlow, Deborah N ; Assimes, Themistocles L ; Franceschini, Nora ; Robinson, Jennifer ; North, Kari E ; Martin, Lisa W ; DePristo, Mark ; Gupta, Namrata ; Escher, Stefan A ; Jansson, Jan-Håkan ; Van Zuydam, Natalie ; Palmer, Colin N A ; Wareham, Nicholas ; Koch, Werner ; Meitinger, Thomas ; Peters, Annette ; Lieb, Wolfgang ; Erbel, Raimund ; Konig, Inke R ; Kruppa, Jochen ; Degenhardt, Franziska ; Gottesman, Omri ; Bottinger, Erwin P ; O'Donnell, Christopher J ; Psaty, Bruce M ; Ballantyne, Christie M ; Abecasis, Goncalo ; Ordovas, Jose M ; Melander, Olle ; Watkins, Hugh ; Orho-Melander, Marju ; Ardissino, Diego ; Loos, Ruth J F ; McPherson, Ruth ; Willer, Cristen J ; Erdmann, Jeanette ; Hall, Alistair S ; Samani, Nilesh J ; Deloukas, Panos ; Schunkert, Heribert ; Wilson, James G ; Kooperberg, Charles ; Rich, Stephen S ; Tracy, Russell P ; Lin, Dan-Yu ; Altshuler, David ; Gabriel, Stacey ; Nickerson, Deborah A ; Jarvik, Gail P ; Cupples, L Adrienne ; Reiner, Alex P ; Boerwinkle, Eric ; Kathiresan, Sekar
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-07, Vol.371 (1), p.22-31
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Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
Author / Creator:Jørgensen, Anders Berg ; Frikke-Schmidt, Ruth ; Nordestgaard, Børge G ; Tybjærg-Hansen, Anne
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-07, Vol.371 (1), p.32-41
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Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia
Author / Creator:Gaudet, Daniel ; Alexander, Veronica J ; Baker, Brenda F ; Brisson, Diane ; Tremblay, Karine ; Singleton, Walter ; Geary, Richard S ; Hughes, Steven G ; Viney, Nicholas J ; Graham, Mark J ; Crooke, Rosanne M ; Witztum, Joseph L ; Brunzell, John D ; Kastelein, John J.P
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2015-07, Vol.373 (5), p.438-447
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Targeting APOC3 in the Familial Chylomicronemia Syndrome
Author / Creator:Gaudet, Daniel ; Brisson, Diane ; Tremblay, Karine ; Alexander, Veronica J ; Singleton, Walter ; Hughes, Steven G ; Geary, Richard S ; Baker, Brenda F ; Graham, Mark J ; Crooke, Rosanne M ; Witztum, Joseph L
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-12, Vol.371 (23), p.2200-2206
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Olezarsen, Acute Pancreatitis, and Familial Chylomicronemia Syndrome
Author / Creator:Stroes, Erik S.G. ; Alexander, Veronica J. ; Karwatowska-Prokopczuk, Ewa ; Hegele, Robert A. ; Arca, Marcello ; Ballantyne, Christie M. ; Soran, Handrean ; Prohaska, Thomas A. ; Xia, Shuting ; Ginsberg, Henry N. ; Witztum, Joseph L. ; Tsimikas, Sotirios
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-05, Vol.390 (19), p.1781-1792
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ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors
Author / Creator:Gordts, Philip L S M ; Nock, Ryan ; Son, Ni-Huiping ; Ramms, Bastian ; Lew, Irene ; Gonzales, Jon C ; Thacker, Bryan E ; Basu, Debapriya ; Lee, Richard G ; Mullick, Adam E ; Graham, Mark J ; Goldberg, Ira J ; Crooke, Rosanne M ; Witztum, Joseph L ; Esko, Jeffrey D
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-08, Vol.126 (8), p.2855-2866
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Olezarsen for Hypertriglyceridemia in Patients at High Cardiovascular Risk
Author / Creator:Bergmark, Brian A. ; Marston, Nicholas A. ; Prohaska, Thomas A. ; Alexander, Veronica J. ; Zimerman, André ; Moura, Filipe A. ; Murphy, Sabina A. ; Goodrich, Erica L. ; Zhang, Shuanglu ; Gaudet, Daniel ; Karwatowska-Prokopczuk, Ewa ; Tsimikas, Sotirios ; Giugliano, Robert P. ; Sabatine, Marc S.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-05, Vol.390 (19), p.1770-1780
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Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection
Author / Creator:Pollin, Toni I ; Damcott, Coleen M ; Shen, Haiqing ; Ott, Sandra H ; Shelton, John ; Horenstein, Richard B ; Post, Wendy ; McLenithan, John C ; Bielak, Lawrence F ; Peyser, Patricia A ; Mitchell, Braxton D ; Miller, Michael ; O'Connell, Jeffrey R ; Shuldiner, Alan R
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-12, Vol.322 (5908), p.1702-1705
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HDL Containing Apolipoprotein C-III is Associated with Insulin Sensitivity: A Multicenter Cohort Study
Author / Creator:Yamamoto, Rain ; Jensen, Majken K ; Aroner, Sarah ; Furtado, Jeremy D ; Rosner, Bernard ; Hu, Frank B ; Balkau, Beverley ; Natali, Andrea ; Ferrannini, Ele ; Baldi, Simona ; Sacks, Frank M
Publisher:US: Oxford University Press
Journal title:The journal of clinical endocrinology and metabolism, 2021-08, Vol.106 (8), p.e2928-e2940
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Effects of Icosapent Ethyl (Eicosapentaenoic Acid Ethyl Ester) on Atherogenic Lipid/Lipoprotein, Apolipoprotein, and Inflammatory Parameters in Patients With Elevated High-Sensitivity C-Reactive Prote...
Author / Creator:Miller, Michael ; Ballantyne, Christie M. ; Bays, Harold E. ; Granowitz, Craig ; Doyle, Ralph T. ; Juliano, Rebecca A. ; Philip, Sephy
Publisher:United States: Elsevier Inc
Journal title:The American journal of cardiology, 2019-09, Vol.124 (5), p.696-701
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ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis
Author / Creator:Capoulade, Romain ; Torzewski, Michael ; Mayr, Manuel ; Chan, Kwan-Leung ; Mathieu, Patrick ; Bossé, Yohan ; Dumesnil, Jean G ; Tam, James ; Teo, Koon K ; Burnap, Sean A. ; Schmid, Jens ; Gobel, Nora ; Franke, Ulrich F W ; Sanchez, Amber ; Witztum, Joseph L ; Yang, Xiaohong ; Yeang, Calvin ; Arsenault, Benoit ; Després, Jean-Pierre ; Pibarot, Philippe ; Tsimikas, Sotirios
Publisher:England: BMJ Publishing Group Ltd and British Cardiovascular Society
Journal title:Heart (British Cardiac Society), 2020-05, Vol.106 (10), p.738-745
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Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a Pilot and Replication Study
Author / Creator:Papakostas, G I ; Shelton, R C ; Kinrys, G ; Henry, M E ; Bakow, B R ; Lipkin, S H ; Pi, B ; Thurmond, L ; Bilello, J A
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2013-03, Vol.18 (3), p.332-339
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CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins
Author / Creator:Shimizu-Albergine, Masami ; Basu, Debapriya ; Kanter, Jenny E ; Kramer, Farah ; Kothari, Vishal ; Barnhart, Shelley ; Thornock, Carissa ; Mullick, Adam E ; Clouet-Foraison, Noemie ; Vaisar, Tomas ; Heinecke, Jay W ; Hegele, Robert A ; Goldberg, Ira J ; Bornfeldt, Karin E
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-11, Vol.131 (22), p.1-16
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Efficacy and safety of olezarsen in lowering apolipoprotein C-III and triglycerides in healthy Japanese Americans
Author / Creator:Karwatowska-Prokopczuk, Ewa ; Lesogor, Anastasia ; Yan, Jing-He ; Hoenlinger, Angelika ; Margolskee, Alison ; Li, Lu ; Tsimikas, Sotirios
Publisher:England: BioMed Central
Journal title:Lipids in health and disease, 2024-10, Vol.23 (1), p.329-12, Article 329
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ApoC-III proteoforms are associated with better lipid, inflammatory, and glucose profiles independent of total apoC-III
Author / Creator:Rehues, Pere ; Girona, Josefa ; Guardiola, Montse ; Ozcariz, Enrique ; Amigó, Núria ; Rosales, Roser ; Esteban, Yaiza ; Banús, Helena ; Gavaldà-Alsina, Gemma ; González-Lleó, Ana ; Rojo-Martínez, Gemma ; Ribalta, Josep
Publisher:England: BioMed Central
Journal title:Cardiovascular diabetology, 2024-12, Vol.23 (1), p.433-15, Article 433
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Apolipoprotein C-III and its defined lipoprotein subspecies in relation to incident diabetes: the Multi-Ethnic Study of Atherosclerosis
Author / Creator:Aroner, Sarah A. ; Furtado, Jeremy D. ; Sacks, Frank M. ; Tsai, Michael Y. ; Mukamal, Kenneth J. ; McClelland, Robyn L. ; Jensen, Majken K.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2019-06, Vol.62 (6), p.981-992
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ApoCIII enrichment in HDL impairs HDL-mediated cholesterol efflux capacity
Author / Creator:Luo, Mengdie ; Liu, Aiying ; Wang, Shuai ; Wang, Tianle ; Hu, Die ; Wu, Sha ; Peng, Daoquan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-05, Vol.7 (1), p.2312-9, Article 2312
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Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation
Author / Creator:Llop, Dídac ; Rehues, Pere ; Paredes, Silvia ; Guardiola, Montse ; Girona, Josefa ; Rosales, Roser ; Esteban, Yaiza ; Masana, Lluís ; Ibarretxe, Daiana ; Vallvé, Joan-Carles ; Ribalta, Josep
Publisher:England: BioMed Central
Journal title:Cardiovascular diabetology, 2025-01, Vol.24 (1), p.9-10, Article 9
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Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk

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Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome

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Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

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Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

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Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia

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Targeting APOC3 in the Familial Chylomicronemia Syndrome

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Olezarsen, Acute Pancreatitis, and Familial Chylomicronemia Syndrome

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ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

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Olezarsen for Hypertriglyceridemia in Patients at High Cardiovascular Risk

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Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

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HDL Containing Apolipoprotein C-III is Associated with Insulin Sensitivity: A Multicenter Cohort Study

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Effects of Icosapent Ethyl (Eicosapentaenoic Acid Ethyl Ester) on Atherogenic Lipid/Lipoprotein, Apolipoprotein, and Inflammatory Parameters in Patients With Elevated High-Sensitivity C-Reactive Prote...

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ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis

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Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a Pilot and Replication Study

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CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins

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Efficacy and safety of olezarsen in lowering apolipoprotein C-III and triglycerides in healthy Japanese Americans

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ApoC-III proteoforms are associated with better lipid, inflammatory, and glucose profiles independent of total apoC-III

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Apolipoprotein C-III and its defined lipoprotein subspecies in relation to incident diabetes: the Multi-Ethnic Study of Atherosclerosis

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ApoCIII enrichment in HDL impairs HDL-mediated cholesterol efflux capacity

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Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation

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