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ArticlesPeer ReviewedFull Text
Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
Author / Creator:Doody, Rachelle S ; Thomas, Ronald G ; Farlow, Martin ; Iwatsubo, Takeshi ; Vellas, Bruno ; Joffe, Steven ; Kieburtz, Karl ; Raman, Rema ; Sun, Xiaoying ; Aisen, Paul S ; Siemers, Eric ; Liu-Seifert, Hong ; Mohs, Richard
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-01, Vol.370 (4), p.311-321
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A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis
Author / Creator:West, Tim ; Kirmess, Kristopher M. ; Meyer, Matthew R. ; Holubasch, Mary S. ; Knapik, Stephanie S. ; Hu, Yan ; Contois, John H. ; Jackson, Erin N. ; Harpstrite, Scott E. ; Bateman, Randall J. ; Holtzman, David M. ; Verghese, Philip B. ; Fogelman, Ilana ; Braunstein, Joel B. ; Yarasheski, Kevin E.
Publisher:England: BioMed Central
Journal title:Molecular neurodegeneration, 2021-05, Vol.16 (1), p.30-12, Article 30
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Plasma proteomics for risk prediction of Alzheimer's disease in the general population
Author / Creator:Yang, Sisi ; Ye, Ziliang ; He, Panpan ; Zhang, Yuanyuan ; Liu, Mengyi ; Zhou, Chun ; Zhang, Yanjun ; Gan, Xiaoqin ; Huang, Yu ; Xiang, Hao ; Qin, Xianhui
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2024-12, Vol.23 (12), p.e14330-n/a
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Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis
Author / Creator:Alabi, Adekunle ; Xia, Xiao-Dan ; Gu, Hong-Mei ; Wang, Faqi ; Deng, Shi-Jun ; Yang, Nana ; Adijiang, Ayinuer ; Douglas, Donna N. ; Kneteman, Norman M. ; Xue, Yazhuo ; Chen, Li ; Qin, Shucun ; Wang, Guiqing ; Zhang, Da-Wei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1889-17, Article 1889
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Nanoparticles enhance brain delivery of blood–brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging
Author / Creator:Koffie, Robert M ; Farrar, Christian T ; Saidi, Laiq-Jan ; William, Christopher M ; Hyman, Bradley T ; Spires-Jones, Tara L
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (46), p.18837-18842
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Dysbetalipoproteinemia: Differentiating Multifactorial Remnant Cholesterol Disease From Genetic ApoE Deficiency
Author / Creator:Paquette, Martine ; Bernard, Sophie ; Paré, Guillaume ; Baass, Alexis
Publisher:US: Oxford University Press
Journal title:The journal of clinical endocrinology and metabolism, 2022-02, Vol.107 (2), p.538-548
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APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction
Author / Creator:Soto, Ileana ; Graham, Leah C. ; Richter, Hannah J. ; Simeone, Stephen N. ; Radell, Jake E. ; Grabowska, Weronika ; Funkhouser, W. Keith ; Howell, Megan C. ; Howell, Gareth R.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2015-10, Vol.13 (10), p.e1002279-e1002279
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Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review
Author / Creator:Oscarsson, Jan ; Hurt-Camejo, Eva
Publisher:England: BioMed Central Ltd
Journal title:Lipids in health and disease, 2017-08, Vol.16 (1), p.149-13, Article 149
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A blood-based signature of cerebrospinal fluid Aβ 1-42 status
Author / Creator:Goudey, Benjamin ; Fung, Bowen J ; Schieber, Christine ; Faux, Noel G
Publisher:England
Journal title:Scientific reports, 2019-12, Vol.9 (1), p.4163
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Association of polygenic risk scores with Alzheimer's disease and plasma biomarkers among Chinese older adults: A community‐based study
Author / Creator:Hou, Tingting ; Liu, Keke ; Fa, Wenxin ; Liu, Cuicui ; Zhu, Min ; Liang, Xiaoyan ; Ren, Yifei ; Xu, Shan ; Wang, Xiang ; Tang, Shi ; Wang, Yongxiang ; Cong, Lin ; Tan, Qihuan ; Du, Yifeng ; Qiu, Chengxuan
Publisher:United States: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-10, Vol.20 (10), p.6669-6681
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Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta
Author / Creator:Melhem, Hassan ; Kallol, Sampada ; Huang, Xiao ; Lüthi, Michael ; Ontsouka, Corneille Edgar ; Keogh, Adrian ; Stroka, Deborah ; Thormann, Wolfgang ; Schneider, Henning ; Albrecht, Christiane
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-04, Vol.9 (1), p.6225, Article 6225
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Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer’s disease patients and controls
Author / Creator:Martínez-Morillo, Eduardo ; Hansson, Oskar ; Atagi, Yuka ; Bu, Guojun ; Minthon, Lennart ; Diamandis, Eleftherios P. ; Nielsen, Henrietta M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2014-05, Vol.127 (5), p.633-643
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Hepatic Niemann-Pick C1–like 1 regulates biliary cholesterol concentration and is a target of ezetimibe
Author / Creator:Temel, Ryan E. ; Tang, Weiqing ; Ma, Yinyan ; Rudel, Lawrence L. ; Willingham, Mark C. ; Ioannou, Yiannis A. ; Davies, Joanna P. ; Nilsson, Lisa-Mari ; Yu, Liqing
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2007-07, Vol.117 (7), p.1968-1978
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CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins
Author / Creator:Shimizu-Albergine, Masami ; Basu, Debapriya ; Kanter, Jenny E. ; Kramer, Farah ; Kothari, Vishal ; Barnhart, Shelley ; Thornock, Carissa ; Mullick, Adam E. ; Clouet-Foraison, Noemie ; Vaisar, Tomas ; Heinecke, Jay W. ; Hegele, Robert A. ; Goldberg, Ira J. ; Bornfeldt, Karin E.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-11, Vol.131 (22), p.1-16
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Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis
Author / Creator:Scholz, Markus ; Horn, Katrin ; Pott, Janne ; Gross, Arnd ; Kleber, Marcus E. ; Delgado, Graciela E. ; Mishra, Pashupati Prasad ; Kirsten, Holger ; Gieger, Christian ; Müller-Nurasyid, Martina ; Tönjes, Anke ; Kovacs, Peter ; Lehtimäki, Terho ; Raitakari, Olli ; Kähönen, Mika ; Gylling, Helena ; Baber, Ronny ; Isermann, Berend ; Stumvoll, Michael ; Loeffler, Markus ; März, Winfried ; Meitinger, Thomas ; Peters, Annette ; Thiery, Joachim ; Teupser, Daniel ; Ceglarek, Uta
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-01, Vol.13 (1), p.143-12, Article 143
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Impact of serum lipids on prognosis in breast cancer patients: a systematic review and meta-analysis
Author / Creator:Gao, Wendong ; Yao, Yilin ; Gao, Qilong ; Zhao, Tiancheng ; Li, Hegen
Publisher:England: BioMed Central Ltd
Journal title:World journal of surgical oncology, 2025-06, Vol.23 (1), p.234-11, Article 234
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Apolipoprotein E gene polymorphism and the risk of cardiovascular disease and type 2 diabetes
Author / Creator:Liu, Sudong ; Liu, Jing ; Weng, Ruiqiang ; Gu, Xiaodong ; Zhong, Zhixiong
Publisher:England: BioMed Central Ltd
Journal title:BMC cardiovascular disorders, 2019-09, Vol.19 (1), p.213-6, Article 213
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Pre-treatment serum apolipoprotein E: a promising prognostic indicator for nasopharyngeal carcinoma
Author / Creator:He, Xian-Ming ; Jiang, Si-Cong ; Luo, Qi-Wei ; Ding, Jian-Wu ; Hu, Rong-Huan ; Hu, Jia-Li ; Liu, Meng-Meng ; Tao, Lei ; Zhang, Jian-Ze ; Wu, Jia-Yin ; Deng, Su ; Zeng, Lei
Publisher:England: BioMed Central Ltd
Journal title:European journal of medical research, 2025-06, Vol.30 (1), p.473-10, Article 473
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Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits
Author / Creator:Engstrom, Allison C. ; Alitin, John Paul M. ; Kapoor, Arunima ; Dutt, Shubir ; Lohman, Trevor ; Sible, Isabel J. ; Marshall, Anisa J. ; Shenasa, Fatemah ; Gaubert, Aimée ; Ferrer, Farrah ; Nguyen, Amy ; Bradford, David Robert ; Rodgers, Kathleen ; Sordo, Lorena ; Head, Elizabeth ; Shao, Xingfeng ; Wang, Danny J. J. ; Nation, Daniel A.
Publisher:United States: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2025-01, Vol.21 (1), p.e14396-n/a
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The Effect of PCSK9 Loss-of-Function Variants on the Postprandial Lipid and ApoB-Lipoprotein Response
Author / Creator:Ooi, Teik Chye ; Krysa, Jacqueline A ; Chaker, Seham ; Abujrad, Hussein ; Mayne, Janice ; Henry, Kathy ; Cousins, Marion ; Raymond, Angela ; Favreau, Colette ; Taljaard, Monica ; Chrétien, Michel ; Mbikay, Majambu ; Proctor, Spencer D ; Vine, Donna F
Publisher:Washington, DC: Endocrine Society
Journal title:The journal of clinical endocrinology and metabolism, 2017-09, Vol.102 (9), p.3452-3460
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Showing 1 to 20 of 268 results

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Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

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A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis

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Plasma proteomics for risk prediction of Alzheimer's disease in the general population

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Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis

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Nanoparticles enhance brain delivery of blood–brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging

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Dysbetalipoproteinemia: Differentiating Multifactorial Remnant Cholesterol Disease From Genetic ApoE Deficiency

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APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction

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Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review

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A blood-based signature of cerebrospinal fluid Aβ 1-42 status

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Association of polygenic risk scores with Alzheimer's disease and plasma biomarkers among Chinese older adults: A community‐based study

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Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta

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Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer’s disease patients and controls

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Hepatic Niemann-Pick C1–like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

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CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins

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Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis

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Impact of serum lipids on prognosis in breast cancer patients: a systematic review and meta-analysis

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Apolipoprotein E gene polymorphism and the risk of cardiovascular disease and type 2 diabetes

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Pre-treatment serum apolipoprotein E: a promising prognostic indicator for nasopharyngeal carcinoma

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Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits

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The Effect of PCSK9 Loss-of-Function Variants on the Postprandial Lipid and ApoB-Lipoprotein Response

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