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A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment
Author / Creator:Schork, Andrew J. ; Won, Hyejung ; Appadurai, Vivek ; Nudel, Ron ; Gandal, Mike ; Delaneau, Olivier ; Revsbech Christiansen, Malene ; Hougaard, David M. ; Bækved-Hansen, Marie ; Bybjerg-Grauholm, Jonas ; Giørtz Pedersen, Marianne ; Agerbo, Esben ; Bøcker Pedersen, Carsten ; Neale, Benjamin M. ; Daly, Mark J. ; Wray, Naomi R. ; Nordentoft, Merete ; Mors, Ole ; Børglum, Anders D. ; Bo Mortensen, Preben ; Buil, Alfonso ; Thompson, Wesley K. ; Geschwind, Daniel H. ; Werge, Thomas
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-03, Vol.22 (3), p.353-361
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Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families
Author / Creator:LaBianca, Sonja ; LaBianca, Jette ; Pagsberg, Anne Katrine ; Jakobsen, Klaus Damgaard ; Appadurai, Vivek ; Buil, Alfonso ; Werge, Thomas
Publisher:New York: Springer US
Journal title:Journal of autism and developmental disorders, 2021-01, Vol.51 (1), p.276-285
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Correction: Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants
Author / Creator:Nudel, Ron ; Appadurai, Vivek ; Buil, Alfonso ; Nordentoft, Merete ; Werge, Thomas
Publisher:London: BioMed Central Ltd
Journal title:Journal of neurodevelopmental disorders, 2023-09, Vol.15 (1), p.1-31, Article 31
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Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants
Author / Creator:Nudel, Ron ; Appadurai, Vivek ; Buil, Alfonso ; Nordentoft, Merete ; Werge, Thomas
Publisher:England: BioMed Central Ltd
Journal title:Journal of neurodevelopmental disorders, 2021-12, Vol.13 (1), p.54-54, Article 54
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A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness
Author / Creator:Nudel, Ron ; Appadurai, Vivek ; Schork, Andrew J. ; Buil, Alfonso ; Bybjerg-Grauholm, Jonas ; Børglum, Anders D. ; Daly, Mark J. ; Mors, Ole ; Hougaard, David M. ; Mortensen, Preben Bo ; Werge, Thomas ; Nordentoft, Merete ; Thompson, Wesley K. ; Benros, Michael E.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Human genetics, 2020-05, Vol.139 (5), p.593-604
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Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
Author / Creator:Fan, Chun Chieh ; McGrath, John J. ; Appadurai, Vivek ; Buil, Alfonso ; Gandal, Michael J. ; Schork, Andrew J. ; Mortensen, Preben Bo ; Agerbo, Esben ; Geschwind, Sandy A. ; Geschwind, Daniel ; Werge, Thomas ; Thompson, Wesley K. ; Pedersen, Carsten Bøcker
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-12, Vol.9 (1), p.5296-7, Article 5296
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Genetic predictors of educational attainment and intelligence test performance predict voter turnout
Author / Creator:Aarøe, Lene ; Appadurai, Vivek ; Hansen, Kasper M. ; Schork, Andrew J. ; Werge, Thomas ; Mors, Ole ; Børglum, Anders D. ; Hougaard, David M. ; Nordentoft, Merete ; Mortensen, Preben B. ; Thompson, Wesley Kurt ; Buil, Alfonso ; Agerbo, Esben ; Petersen, Michael Bang
Publisher:London: Nature Publishing Group UK
Journal title:Nature human behaviour, 2021-02, Vol.5 (2), p.281-291
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Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks
Author / Creator:Appadurai, Vivek ; Bybjerg-Grauholm, Jonas ; Krebs, Morten Dybdahl ; Rosengren, Anders ; Buil, Alfonso ; Ingason, Andrés ; Mors, Ole ; Børglum, Anders D. ; Hougaard, David M. ; Nordentoft, Merete ; Mortensen, Preben B. ; Delaneau, Olivier ; Werge, Thomas ; Schork, Andrew J.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2023-01, Vol.6 (1), p.101-101, Article 101
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POLG2 deficiency causes adult‐onset syndromic sensory neuropathy, ataxia and parkinsonism
Author / Creator:Van Maldergem, Lionel ; Besse, Arnaud ; De Paepe, Boel ; Blakely, Emma L. ; Appadurai, Vivek ; Humble, Margaret M. ; Piard, Juliette ; Craig, Kate ; He, Langping ; Hella, Pierre ; Debray, François‐Guillaume ; Martin, Jean‐Jacques ; Gaussen, Marion ; Laloux, Patrice ; Stevanin, Giovanni ; Van Coster, Rudy ; Taylor, Robert W. ; Copeland, William C. ; Mormont, Eric ; Bonnen, Penelope E.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Annals of clinical and translational neurology, 2017-01, Vol.4 (1), p.4-14
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Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
Author / Creator:Gandal, Michael J. ; Haney, Jillian R. ; Parikshak, Neelroop N. ; Leppa, Virpi ; Ramaswami, Gokul ; Hartl, Chris ; Schork, Andrew J. ; Appadurai, Vivek ; Buil, Alfonso ; Werge, Thomas M. ; Liu, Chunyu ; White, Kevin P. ; Horvath, Steve ; Geschwind, Daniel H. ; Sestan, Nenad ; Vaccarino, Flora ; Gerstein, Mark ; Weissman, Sherman ; Pochareddy, Sirisha ; State, Matthew ; Knowles, James ; Farnham, Peggy ; Akbarian, Schahram ; Pinto, Dalila ; Van Baekl, Harm ; Dracheva, Stella ; Jaffe, Andrew ; Hyde, Thomas ; Zandi, Peter ; Crawford, Gregory ; Sullivan, Pat ; Thompson, Wesley Kurt ; Mortensen, Preben Bo ; Agerbo, Esben ; Pedersen, Marianne Giørtz ; Pedersen, Carsten Bøcker ; Mors, Ole ; Børglum, Anders D. ; Nordentoft, Merete ; Hougaard, David M. ; Bybjerg-Grauholm, Jonas ; Bækvad-Hansen, Marie ; Martin, Alicia R. ; Dumont, Ashley ; Stevens, Christine ; Churchhouse, Claire ; Howrigan, Daniel P. ; Palmer, Duncan S. ; Robinson, Elise B. ; Satterstrom, Kyle F. ; Cerrato, Felecia ; Huang, Hailiang ; Goldstein, Jacqueline ; Moran, Jennifer ; Julian, Joanna Martin ; Kimberly, Maller ; Patrick, Chambert ; Turley, Patrick ; Walters, Raymond ; Belliveau, Rich ; Ripke, Stephan ; Poterba, Timothy ; Daly, Mark J. ; Neale, Benjamin ; Fromer, Menachem ; Roussos, Panos ; Johnson, Jessica S. ; Shah, Hardik R. ; Mahajan, Milind C. ; Schadt, Eric ; Haroutunian, Vahram ; Ruderfer, Douglas M. ; Buxbaum, Joseph D. ; Sieberts, Solveig K. ; Dang, Kristen ; Logsdon, Ben ; Mangravite, Lara M. ; Peters, Mette ; Gur, Raquel E. ; Hahn, Chang-Gyu ; Devlin, Bernie ; Klei, Lambertus L. ; Lewis, David ; Lipska, Barbara ; Hirai, Keisuke ; Toyoshiba, Hiroyoshi ; Domenici, Enrico
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6376), p.693-697
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Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study
Author / Creator:Erlangsen, Annette ; Appadurai, Vivek ; Wang, Yunpeng ; Turecki, Gustavo ; Mors, Ole ; Werge, Thomas ; Mortensen, Preben B. ; Starnawska, Anna ; Børglum, Anders D. ; Schork, Andrew ; Nudel, Ron ; Bækvad-Hansen, Marie ; Bybjerg-Grauholm, Jonas ; Hougaard, David M. ; Thompson, Wesley K. ; Nordentoft, Merete ; Agerbo, Esben
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2020-10, Vol.25 (10), p.2410-2421
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Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder
Author / Creator:Dahl, Andrew ; Thompson, Michael ; An, Ulzee ; Krebs, Morten ; Appadurai, Vivek ; Border, Richard ; Bacanu, Silviu-Alin ; Werge, Thomas ; Flint, Jonathan ; Schork, Andrew J. ; Sankararaman, Sriram ; Kendler, Kenneth S. ; Cai, Na
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2023-12, Vol.55 (12), p.2082-2093
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Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
Author / Creator:Liu, Xueping ; Helenius, Dorte ; Skotte, Line ; Beaumont, Robin N. ; Wielscher, Matthias ; Geller, Frank ; Juodakis, Julius ; Mahajan, Anubha ; Bradfield, Jonathan P. ; Lin, Frederick T. J. ; Vogelezang, Suzanne ; Bustamante, Mariona ; Ahluwalia, Tarunveer S. ; Pitkänen, Niina ; Wang, Carol A. ; Bacelis, Jonas ; Borges, Maria C. ; Zhang, Ge ; Bedell, Bruce A. ; Rossi, Robert M. ; Skogstrand, Kristin ; Peng, Shouneng ; Thompson, Wesley K. ; Appadurai, Vivek ; Lawlor, Debbie A. ; Kalliala, Ilkka ; Power, Christine ; McCarthy, Mark I. ; Boyd, Heather A. ; Marazita, Mary L. ; Hakonarson, Hakon ; Hayes, M. Geoffrey ; Scholtens, Denise M. ; Rivadeneira, Fernando ; Jaddoe, Vincent W. V. ; Vinding, Rebecca K. ; Bisgaard, Hans ; Knight, Bridget A. ; Pahkala, Katja ; Raitakari, Olli ; Helgeland, Øyvind ; Johansson, Stefan ; Njølstad, Pål R. ; Fadista, João ; Schork, Andrew J. ; Nudel, Ron ; Miller, Daniel E. ; Chen, Xiaoting ; Weirauch, Matthew T. ; Mortensen, Preben Bo ; Børglum, Anders D. ; Nordentoft, Merete ; Mors, Ole ; Hao, Ke ; Ryckman, Kelli K. ; Hougaard, David M. ; Kottyan, Leah C. ; Pennell, Craig E. ; Lyytikainen, Leo-Pekka ; Bønnelykke, Klaus ; Vrijheid, Martine ; Felix, Janine F. ; Lowe, William L. ; Grant, Struan F. A. ; Hyppönen, Elina ; Jacobsson, Bo ; Jarvelin, Marjo-Riitta ; Muglia, Louis J. ; Murray, Jeffrey C. ; Freathy, Rachel M. ; Werge, Thomas M. ; Melbye, Mads ; Buil, Alfonso ; Feenstra, Bjarke
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.3927-13, Article 3927
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Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder
Author / Creator:LaBianca, Sonja ; Brikell, Isabell ; Helenius, Dorte ; Loughnan, Robert ; Mefford, Joel ; Palmer, Clare E. ; Walker, Rebecca ; Gådin, Jesper R. ; Krebs, Morten ; Appadurai, Vivek ; Vaez, Morteza ; Agerbo, Esben ; Pedersen, Marianne Giørtz ; Børglum, Anders D. ; Hougaard, David M. ; Mors, Ole ; Nordentoft, Merete ; Mortensen, Preben Bo ; Kendler, Kenneth S. ; Jernigan, Terry L. ; Geschwind, Daniel H. ; Ingason, Andrés ; Dahl, Andrew W. ; Zaitlen, Noah ; Dalsgaard, Søren ; Werge, Thomas M. ; Schork, Andrew J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2024-02, Vol.56 (2), p.234-244
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A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population
Author / Creator:Nudel, Ron ; Wang, Yunpeng ; Appadurai, Vivek ; Schork, Andrew J. ; Buil, Alfonso ; Agerbo, Esben ; Bybjerg-Grauholm, Jonas ; Børglum, Anders D. ; Daly, Mark J. ; Mors, Ole ; Hougaard, David M. ; Mortensen, Preben B. ; Werge, Thomas ; Nordentoft, Merete ; Thompson, Wesley K. ; Benros, Michael E.
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2019-11, Vol.9 (1), p.283-10, Article 283
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Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity
Author / Creator:Rajagopal, Veera M. ; Ganna, Andrea ; Coleman, Jonathan R. I. ; Allegrini, Andrea ; Voloudakis, Georgios ; Grove, Jakob ; Als, Thomas D. ; Horsdal, Henriette T. ; Petersen, Liselotte ; Appadurai, Vivek ; Schork, Andrew ; Buil, Alfonso ; Bulik, Cynthia M. ; Bybjerg-Grauholm, Jonas ; Bækvad-Hansen, Marie ; Hougaard, David M. ; Mors, Ole ; Nordentoft, Merete ; Werge, Thomas ; Mortensen, Preben Bo ; Breen, Gerome ; Roussos, Panos ; Plomin, Robert ; Agerbo, Esben ; Børglum, Anders D. ; Demontis, Ditte
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-01, Vol.13 (1), p.429-16, Article 429
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O4.6. GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS
Author / Creator:Benros, Michael ; Nudel, Ron ; Wang, Yunpeng ; Appadurai, Vivek ; Schork, Andrew ; Agerbo, Esben ; Werge, Thomas ; Nordentoft, Merete ; Mortensen, Preben ; Buil, Alfonso ; Thompson, Wesley
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2018-04, Vol.44 (suppl_1), p.S85-S85
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Association between GLP-1 receptor gene polymorphisms with reward learning, anhedonia and depression diagnosis
Author / Creator:Yapici-Eser, Hale ; Appadurai, Vivek ; Eren, Candan Yasemin ; Yazici, Dilek ; Chen, Chia-Yen ; Öngür, Dost ; Pizzagalli, Diego A. ; Werge, Thomas ; Hall, Mei-Hua
Publisher:England: Cambridge University Press
Journal title:Acta neuropsychiatrica, 2020-08, Vol.32 (4), p.218-225
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Analysis of exonic deletions in a large population study provides novel insights into NRXN1 pathology
Author / Creator:Montalbano, Simone ; Krebs, Morten Dybdahl ; Rosengren, Anders ; Vaez, Morteza ; Hellberg, Kajsa-Lotta Georgii ; Mortensen, Preben B. ; Børglum, Anders D. ; Geschwind, Daniel H. ; Raznahan, Armin ; Thompson, Wesley K. ; Helenius, Dorte ; Werge, Thomas ; Ingason, Andrés
Publisher:London: Nature Publishing Group UK
Journal title:Npj genomic medicine, 2024-12, Vol.9 (1), p.67-10, Article 67
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Phenotype integration improves power and preserves specificity in biobank-based genetic studies of MDD
Author / Creator:Dahl, Andrew ; Thompson, Michael ; An, Ulzee ; Krebs, Morten Dybdahl ; Appadurai, Vivek ; Border, Richard ; Silviu-Alin Bacanu ; Werge, Thomas ; Flint, Jonathan ; Schork, Andrew Joseph ; Sankararaman, Sriram ; Kendler, Kenneth ; Cai, Na
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2023-01
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Showing 1 to 20 of 26 results

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A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

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Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families

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Correction: Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants

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Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants

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A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness

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Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

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Genetic predictors of educational attainment and intelligence test performance predict voter turnout

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Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks

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POLG2 deficiency causes adult‐onset syndromic sensory neuropathy, ataxia and parkinsonism

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Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

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Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

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Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder

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Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

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Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder

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A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

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Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity

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O4.6. GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS

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Association between GLP-1 receptor gene polymorphisms with reward learning, anhedonia and depression diagnosis

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Analysis of exonic deletions in a large population study provides novel insights into NRXN1 pathology

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Phenotype integration improves power and preserves specificity in biobank-based genetic studies of MDD

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