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A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins
Author / Creator:Sitaram, Anand ; Yin, Yunqiang ; Zamaitis, Tammy ; Zhang, Bo ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2022-11, Vol.18 (11), p.e1010656-e1010656
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The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole
Author / Creator:Williams, Paul D. E. ; Brewer, Matthew T. ; Aroian, Raffi V. ; Robertson, Alan P. ; Martin, Richard J.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-05, Vol.20 (5), p.e1011835
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Resistance to Cry14A family Bacillus thuringiensis crystal proteins in Caenornabditis elegans operates via the nhr-31 transcription factor and vacuolar-type ATPase pathway
Author / Creator:Kim, Youmie ; Nguyen, Thanh-Thanh ; Durning, Daniel J. ; Ishidate, Takao ; Aydemir, Ozkan ; Mello, Craig C. ; Hu, Yan ; Kahn, Theodore W. ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-10, Vol.20 (10), p.e1012611
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The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families
Author / Creator:Schwarz, Erich M ; Hu, Yan ; Antoshechkin, Igor ; Miller, Melanie M ; Sternberg, Paul W ; Aroian, Raffi V
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2015-04, Vol.47 (4), p.416-422
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Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains
Author / Creator:Shaver, Amanda O. ; Wit, Janneke ; Dilks, Clayton M. ; Crombie, Timothy A. ; Li, Hanchen ; Aroian, Raffi V. ; Andersen, Erik C.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-04, Vol.19 (4), p.e1011285-e1011285
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Immune reactivity and host modulatory roles of two novel Haemonchus contortus cathepsin B-like proteases
Author / Creator:Bakshi, Mariam ; Tuo, Wenbin ; Aroian, Raffi V. ; Zarlenga, Dante
Publisher:England: BioMed Central Ltd
Journal title:Parasites & vectors, 2021-11, Vol.14 (1), p.580-580, Article 580
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Nematode ascarosides attenuate mammalian type 2 inflammatory responses
Author / Creator:Shinoda, Kenta ; Choe, Andrea ; Hirahara, Kiyoshi ; Kiuchi, Masahiro ; Kokubo, Kota ; Ichikawa, Tomomi ; Hoki, Jason S. ; Suzuki, Akane S. ; Bose, Neelanjan ; Appleton, Judith A. ; Aroian, Raffi V. ; Schroeder, Frank C. ; Sternberg, Paul W. ; Nakayama, Toshinori
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (9), p.1-10
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Extensive Comparison of the Effect of Anthelmintic Classes on Diverse Nematodes
Author / Creator:Hu, Yan ; Ellis, Brian L ; Yiu, Ying Y ; Miller, Melanie M ; Urban, Joseph F ; Shi, Linda Z ; Aroian, Raffi V ; Hofmann, Andreas
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-07, Vol.8 (7), p.e70702-e70702
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Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes
Author / Creator:Mirza, Zeynep ; Soto, Ernesto R. ; Hu, Yan ; Nguyen, Thanh-Thanh ; Koch, David ; Aroian, Raffi V. ; Ostroff, Gary R.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-06, Vol.25 (13), p.2958
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Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites
Author / Creator:Hoang, Duy ; Flanagan, Kelly ; Ding, Qian ; Cazeault, Nicholas R. ; Li, Hanchen ; Díaz-Valerio, Stefani ; Rus, Florentina ; Darfour, Esther A. ; Kass, Elizabeth ; Petersson, Katherine H. ; Nielsen, Martin K. ; Liesegang, Heiko ; Ostroff, Gary R. ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2024-10, Vol.18 (10), p.e0012611
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Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo
Author / Creator:Bischof, Larry J. ; Kao, Cheng-Yuan ; Los, Ferdinand C. O. ; Gonzalez, Manuel R. ; Shen, Zhouxin ; Briggs, Steven P. ; van der Goot, F. Gisou ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2008-10, Vol.4 (10), p.e1000176
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ArticlesPeer ReviewedFull Text
Hypoxia and the Hypoxic Response Pathway Protect against Pore-Forming Toxins in C. elegans
Author / Creator:Bellier, Audrey ; Chen, Chang-Shi ; Kao, Cheng-Yuan ; Cinar, Hediye N. ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2009-12, Vol.5 (12), p.e1000689-1000689
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Global Functional Analyses of Cellular Responses to Pore-Forming Toxins
Author / Creator:Kao, Cheng-Yuan ; Los, Ferdinand C. O. ; Huffman, Danielle L. ; Wachi, Shinichiro ; Kloft, Nicole ; Husmann, Matthias ; Karabrahimi, Valbona ; Schwartz, Jean-Louis ; Bellier, Audrey ; Ha, Christine ; Sagong, Youn ; Fan, Hui ; Ghosh, Partho ; Hsieh, Mindy ; Hsu, Chih-Shen ; Chen, Li ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2011-03, Vol.7 (3), p.e1001314
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In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites
Author / Creator:Hu, Yan ; Miller, Melanie ; Zhang, Bo ; Nguyen, Thanh-Thanh ; Nielsen, Martin K. ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2018-05, Vol.12 (5), p.e0006506-e0006506
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The New Anthelmintic Tribendimidine is an L-type (Levamisole and Pyrantel) Nicotinic Acetylcholine Receptor Agonist
Author / Creator:Hu, Yan ; Xiao, Shu-Hua ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2009-08, Vol.3 (8), p.e499-e499
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A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection
Author / Creator:Noon, Jason B. ; Schwarz, Erich M. ; Ostroff, Gary R. ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-04, Vol.13 (4), p.e0007345
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Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility
Author / Creator:Hu, Yan ; Platzer, Edward G ; Bellier, Audrey ; Aroian, Raffi V
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (13), p.5955-5960
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Mitogen-Activated Protein Kinase Pathways Defend against Bacterial Pore-Forming Toxins
Author / Creator:Huffman, Danielle L. ; Abrami, Laurence ; Sasik, Roman ; Corbeil, Jacques ; van der Goot, F. Gisou ; Aroian, Raffi V. ; Collier, R. John
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (30), p.10995-11000
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C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens
Author / Creator:Ju, Shouyong ; Chen, Hanqiao ; Wang, Shaoying ; Lin, Jian ; Ma, Yanli ; Aroian, Raffi V. ; Peng, Donghai ; Sun, Ming
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2022-06, Vol.5 (1), p.643-643, Article 643
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Bacillus thuringiensis-derived Cry5B Has Potent Anthelmintic Activity against Ascaris suum
Author / Creator:Urban, Joseph F. ; Hu, Yan ; Miller, Melanie M. ; Scheib, Ulrike ; Yiu, Ying Y. ; Aroian, Raffi V.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2013-06, Vol.7 (6), p.e2263
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Showing 1 to 20 of 53 results

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A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins

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The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole

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Resistance to Cry14A family Bacillus thuringiensis crystal proteins in Caenornabditis elegans operates via the nhr-31 transcription factor and vacuolar-type ATPase pathway

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The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families

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Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains

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Immune reactivity and host modulatory roles of two novel Haemonchus contortus cathepsin B-like proteases

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Nematode ascarosides attenuate mammalian type 2 inflammatory responses

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Extensive Comparison of the Effect of Anthelmintic Classes on Diverse Nematodes

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Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes

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Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites

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Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo

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Hypoxia and the Hypoxic Response Pathway Protect against Pore-Forming Toxins in C. elegans

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Global Functional Analyses of Cellular Responses to Pore-Forming Toxins

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In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites

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The New Anthelmintic Tribendimidine is an L-type (Levamisole and Pyrantel) Nicotinic Acetylcholine Receptor Agonist

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A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection

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Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility

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Mitogen-Activated Protein Kinase Pathways Defend against Bacterial Pore-Forming Toxins

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C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens

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Bacillus thuringiensis-derived Cry5B Has Potent Anthelmintic Activity against Ascaris suum

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