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Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer
Author / Creator:Li, Jing ; Ohmura, Shunya ; Marchetto, Aruna ; Orth, Martin F. ; Imle, Roland ; Dallmayer, Marlene ; Musa, Julian ; Knott, Maximilian M. L. ; Hölting, Tilman L. B. ; Stein, Stefanie ; Funk, Cornelius M. ; Sastre, Ana ; Alonso, Javier ; Bestvater, Felix ; Kasan, Merve ; Romero-Pérez, Laura ; Hartmann, Wolfgang ; Ranft, Andreas ; Banito, Ana ; Dirksen, Uta ; Kirchner, Thomas ; Cidre-Aranaz, Florencia ; Grünewald, Thomas G. P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-09, Vol.12 (1), p.5356-5356, Article 5356
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Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma
Author / Creator:Hering, Marvin ; Madi, Alaa ; Sandhoff, Roger ; Ma, Sicong ; Wu, Jingxia ; Mieg, Alessa ; Richter, Karsten ; Mohr, Kerstin ; Knabe, Nora ; Stichling, Diana ; Poschet, Gernot ; Bestvater, Felix ; Frank, Larissa ; Utikal, Jochen ; Umansky, Viktor ; Cui, Guoliang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-07, Vol.15 (1), p.6067-18, Article 6067
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A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis
Author / Creator:Grimm, Elisabeth ; van der Hoeven, Franciscus ; Sardella, Donato ; Willig, Katrin I. ; Engel, Ulrike ; Veits, Nisha ; Engel, Robert ; Cavalcanti-Adam, Elisabetta Ada ; Bestvater, Felix ; Bordoni, Luca ; Jennemann, Richard ; Schönig, Kai ; Schiessl, Ina Maria ; Sandhoff, Roger
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2022-09, Vol.17 (9), p.e0273660-e0273660
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Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
Author / Creator:Ohmura, Shunya ; Marchetto, Aruna ; Orth, Martin F. ; Li, Jing ; Jabar, Susanne ; Ranft, Andreas ; Vinca, Endrit ; Ceranski, Katharina ; Carreño-Gonzalez, Martha J. ; Romero-Pérez, Laura ; Wehweck, Fabienne S. ; Musa, Julian ; Bestvater, Felix ; Knott, Maximilian M. L. ; Hölting, Tilman L. B. ; Hartmann, Wolfgang ; Dirksen, Uta ; Kirchner, Thomas ; Cidre-Aranaz, Florencia ; Grünewald, Thomas G. P.
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2021-07, Vol.20 (1), p.97-97, Article 97
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Challenges and Contradictions of Metal Nano-Particle Applications for Radio-Sensitivity Enhancement in Cancer Therapy
Author / Creator:Pagáčová, Eva ; Štefančíková, Lenka ; Schmidt-Kaler, Franz ; Hildenbrand, Georg ; Vičar, Tomáš ; Depeš, Daniel ; Lee, Jin-Ho ; Bestvater, Felix ; Lacombe, Sandrine ; Porcel, Erika ; Roux, Stéphane ; Wenz, Frederik ; Kopečná, Olga ; Falková, Iva ; Hausmann, Michael ; Falk, Martin
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-01, Vol.20 (3), p.588
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Challenges for Super-Resolution Localization Microscopy and Biomolecular Fluorescent Nano-Probing in Cancer Research
Author / Creator:Hausmann, Michael ; Ilić, Nataša ; Pilarczyk, Götz ; Lee, Jin-Ho ; Logeswaran, Abiramy ; Borroni, Aurora ; Krufczik, Matthias ; Theda, Franziska ; Waltrich, Nadine ; Bestvater, Felix ; Hildenbrand, Georg ; Cremer, Christoph ; Blank, Michael
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-09, Vol.18 (10), p.2066
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Dose enhancement effects of gold nanoparticles specifically targeting RNA in breast cancer cells
Author / Creator:Hildenbrand, Georg ; Metzler, Philipp ; Pilarczyk, Götz ; Bobu, Vladimir ; Kriz, Wilhelm ; Hosser, Hiltraud ; Fleckenstein, Jens ; Krufczik, Matthias ; Bestvater, Felix ; Wenz, Frederik ; Hausmann, Michael
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-01, Vol.13 (1), p.e0190183-e0190183
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Recruitment of 53BP1 Proteins for DNA Repair and Persistence of Repair Clusters Differ for Cell Types as Detected by Single Molecule Localization Microscopy
Author / Creator:Bobkova, Elizaveta ; Depes, Daniel ; Lee, Jin-Ho ; Jezkova, Lucie ; Falkova, Iva ; Pagacova, Eva ; Kopecna, Olga ; Zadneprianetc, Mariia ; Bacikova, Alena ; Kulikova, Elena ; Smirnova, Elena ; Bulanova, Tatiana ; Boreyko, Alla ; Krasavin, Evgeny ; Wenz, Frederik ; Bestvater, Felix ; Hildenbrand, Georg ; Hausmann, Michael ; Falk, Martin
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-11, Vol.19 (12), p.3713
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Nano-Architecture of Persistent Focal DNA Damage Regions in the Minipig Epidermis Weeks after Acute γ-Irradiation
Author / Creator:Scherthan, Harry ; Geiger, Beatrice ; Ridinger, David ; Müller, Jessica ; Riccobono, Diane ; Bestvater, Felix ; Port, Matthias ; Hausmann, Michael
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-10, Vol.13 (10), p.1518
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Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells
Author / Creator:Dobešová, Lucie ; Gier, Theresa ; Kopečná, Olga ; Pagáčová, Eva ; Vičar, Tomáš ; Bestvater, Felix ; Toufar, Jiří ; Bačíková, Alena ; Kopel, Pavel ; Fedr, Radek ; Hildenbrand, Georg ; Falková, Iva ; Falk, Martin ; Hausmann, Michael
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2022-01, Vol.14 (1), p.166
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Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma
Author / Creator:Jin, Jia Xiang ; Fuchslocher, Fabia ; Carreno‐Gonzalez, Martha ; Zahnow, Felina ; Ceranski, A. Katharina ; Will, Rainer ; Helm, Dominic ; Bestvater, Felix ; Banito, Ana ; Imle, Roland ; Ohmura, Shunya ; Cidre‐Aranaz, Florencia ; Grünewald, Thomas G. P.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer communications (London, England), 2025-05, Vol.45 (5), p.494-499
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Alanyl-Glutamine Restores Tight Junction Organization after Disruption by a Conventional Peritoneal Dialysis Fluid
Author / Creator:Bartosova, Maria ; Herzog, Rebecca ; Ridinger, David ; Levai, Eszter ; Jenei, Hanna ; Zhang, Conghui ; González Mateo, Guadalupe T. ; Marinovic, Iva ; Hackert, Thilo ; Bestvater, Felix ; Hausmann, Michael ; López Cabrera, Manuel ; Kratochwill, Klaus ; Zarogiannis, Sotirios G. ; Schmitt, Claus Peter
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2020-08, Vol.10 (8), p.1178
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ArticlesPeer ReviewedFull Text
Quantitative Analysis of Nucleic Acid Hybridization on Magnetic Particles and Quantum Dot-Based Probes
Author / Creator:Lim, Sun Hee ; Bestvater, Felix ; Buchy, Philippe ; Mardy, Sek ; Yu, Alexey Dan Chin
Publisher:Switzerland: MDPI AG
Journal title:Sensors (Basel, Switzerland), 2009-07, Vol.9 (7), p.5590-5599
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Blockade of Glycosphingolipid Synthesis Inhibits Cell Cycle and Spheroid Growth of Colon Cancer Cells In Vitro and Experimental Colon Cancer Incidence In Vivo
Author / Creator:Jennemann, Richard ; Volz, Martina ; Bestvater, Felix ; Schmidt, Claudia ; Richter, Karsten ; Kaden, Sylvia ; Müthing, Johannes ; Gröne, Hermann-Josef ; Sandhoff, Roger
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-10, Vol.22 (19), p.10539
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An Experimental Workflow for Studying Barrier Integrity, Permeability, and Tight Junction Composition and Localization in a Single Endothelial Cell Monolayer: Proof of Concept
Author / Creator:Bartosova, Maria ; Ridinger, David ; Marinovic, Iva ; Heigwer, Jana ; Zhang, Conghui ; Levai, Eszter ; Westhoff, Jens H. ; Schaefer, Franz ; Terjung, Stefan ; Hildenbrand, Georg ; Krunic, Damir ; Bestvater, Felix ; Hausmann, Michael ; Schmitt, Claus Peter ; Zarogiannis, Sotirios G.
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-08, Vol.22 (15), p.8178
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Nanostructure of Clustered DNA Damage in Leukocytes after In-Solution Irradiation with the Alpha Emitter Ra-223
Author / Creator:Scherthan, Harry ; Lee, Jin-Ho ; Maus, Emanuel ; Schumann, Sarah ; Muhtadi, Razan ; Chojowski, Robert ; Port, Matthias ; Lassmann, Michael ; Bestvater, Felix ; Hausmann, Michael
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2019-11, Vol.11 (12), p.1877
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Localisation Microscopy of Breast Epithelial ErbB-2 Receptors and Gap Junctions: Trafficking after γ-Irradiation, Neuregulin-1β, and Trastuzumab Application
Author / Creator:Pilarczyk, Götz ; Nesnidal, Ines ; Gunkel, Manuel ; Bach, Margund ; Bestvater, Felix ; Hausmann, Michael
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-02, Vol.18 (2), p.362-362
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CD73 Overexpression in Podocytes: A Novel Marker of Podocyte Injury in Human Kidney Disease
Author / Creator:Popovic, Zoran V. ; Bestvater, Felix ; Krunic, Damir ; Krämer, Bernhard K. ; Bergner, Raoul ; Löffler, Christian ; Hocher, Berthold ; Marx, Alexander ; Porubsky, Stefan
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-07, Vol.22 (14), p.7642
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Spatial Arrangements of Connexin43 in Cancer Related Cells and Re-Arrangements under Treatment Conditions: Investigations on the Nano-Scale by Super-Resolution Localization Light Microscopy
Author / Creator:Pilarczyk, Götz ; Papenfuß, Franziska ; Bestvater, Felix ; Hausmann, Michael
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2019-03, Vol.11 (3), p.301
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Localization Microscopy Analyses of MRE11 Clusters in 3D-Conserved Cell Nuclei of Different Cell Lines
Author / Creator:Eryilmaz, Marion ; Schmitt, Eberhard ; Krufczik, Matthias ; Theda, Franziska ; Lee, Jin-Ho ; Cremer, Christoph ; Bestvater, Felix ; Schaufler, Wladimir ; Hausmann, Michael ; Hildenbrand, Georg
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2018-01, Vol.10 (1), p.25
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Showing 1 to 20 of 26 results

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Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer

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Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma

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A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis

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Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma

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Challenges and Contradictions of Metal Nano-Particle Applications for Radio-Sensitivity Enhancement in Cancer Therapy

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Challenges for Super-Resolution Localization Microscopy and Biomolecular Fluorescent Nano-Probing in Cancer Research

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Dose enhancement effects of gold nanoparticles specifically targeting RNA in breast cancer cells

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Recruitment of 53BP1 Proteins for DNA Repair and Persistence of Repair Clusters Differ for Cell Types as Detected by Single Molecule Localization Microscopy

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Nano-Architecture of Persistent Focal DNA Damage Regions in the Minipig Epidermis Weeks after Acute γ-Irradiation

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Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells

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Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma

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Alanyl-Glutamine Restores Tight Junction Organization after Disruption by a Conventional Peritoneal Dialysis Fluid

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Quantitative Analysis of Nucleic Acid Hybridization on Magnetic Particles and Quantum Dot-Based Probes

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Blockade of Glycosphingolipid Synthesis Inhibits Cell Cycle and Spheroid Growth of Colon Cancer Cells In Vitro and Experimental Colon Cancer Incidence In Vivo

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An Experimental Workflow for Studying Barrier Integrity, Permeability, and Tight Junction Composition and Localization in a Single Endothelial Cell Monolayer: Proof of Concept

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Nanostructure of Clustered DNA Damage in Leukocytes after In-Solution Irradiation with the Alpha Emitter Ra-223

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Localisation Microscopy of Breast Epithelial ErbB-2 Receptors and Gap Junctions: Trafficking after γ-Irradiation, Neuregulin-1β, and Trastuzumab Application

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CD73 Overexpression in Podocytes: A Novel Marker of Podocyte Injury in Human Kidney Disease

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Spatial Arrangements of Connexin43 in Cancer Related Cells and Re-Arrangements under Treatment Conditions: Investigations on the Nano-Scale by Super-Resolution Localization Light Microscopy

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Localization Microscopy Analyses of MRE11 Clusters in 3D-Conserved Cell Nuclei of Different Cell Lines

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