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Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial
Author / Creator:Qin, Shukui ; Chen, Minshan ; Kudo, Masatoshi ; Yopp, Adam C ; Wang, Lu ; Tak, Won Young ; Lian, Qinshu ; Spahn, Jessica H ; Wang, Yulei ; Chow, Pierce K H ; Poursoltan, Pirooz ; Kiberu, Andrew ; Chittajallu, Renuka ; Sood, Siddarth ; Stauber, Rudolf ; Peck-Radosavljevic, Markus ; Decaestecker, Jochen ; Verset, Gontran ; Cunha Júnior, Ademar ; Faria, Luiza ; Asselah, Jamil ; Brahmania, Mayur ; Li, Qiang ; Chen, Zhendong ; Zhao, Haitao ; Liu, Hongming ; Wu, Feixiang ; Zheng, Qichang ; Li, Haitao ; Wen, Tianfu ; Qin, Shukui ; Liu, Yunpeng ; Chen, Minshan ; Bai, Yuxian ; Zhao, Hong ; Yin, Tao ; Ding, Youming ; Jia, Weidong ; Xia, Yongxiang ; Xia, Qiang ; Guzmán, Adrián ; Corrales, Luis ; Kubala, Eugen ; Blanc, Jean Frederic ; Borg, Christophe ; Decaens, Thomas ; Uguen, Thomas ; Heurgue, Alexandra ; Trojan, Joerg ; Gonzalez-Carmona, Maria Angeles ; Schotten, Clemens ; Kandulski, Arne ; Yau, Thomas ; Scartozzi, Mario ; Leonardi, Francesco ; Ghidini, Michele ; Kudo, Masatoshi ; Koga, Hironori ; Kawamura, Yusuke ; Hasegawa, Kiyoshi ; Marusawa, Hiroyuki ; Hayashi, Hiromitsu ; Lee, Han Chu ; Paik, Seung Woon ; Kim, Do Young ; Jeong, Sook-Hyang ; Kim, Hyeyeong ; Yoon, Seung Kew ; Yoon, Jung-Hwan ; Villalobos, Ricardo ; Martinez Rodriguez, Jorge Luis ; Oyervides Juarez, Victor ; Hernández, Carlos Alberto ; de Vos-Geelen, Judith ; Gane, Edward ; Torres Mattos, Cesar ; Alyasova, Anna ; Sekacheva, Marina ; Ledin, Evgeny ; Toh, Han Chong ; Lopez Lopez, Carlos ; Muñoz Martin, Andres Jesus ; Reig Monzón, Maria ; Delgado Mingorance, Ignacio ; Minguez Rosique, Beatriz ; Huang, Yi-Hsiang ; Huang, Jee-Fu ; Su, Wei-Wen ; Maneenil, Kunlatida ; Harputluoglu, Hakan ; Buchschacher, Gary ; Xiong, Henry ; Patel, Mital ; Li, Daneng ; Brooks, Gabriel ; Patel, Reema ; Kardosh, Adel ; Shah, Ashesh ; Burris III, Howard ; Hsiehchen, David
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2023-11, Vol.402 (10415), p.1835-1847
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Evolving therapeutic landscape of advanced hepatocellular carcinoma
Author / Creator:Yang, Chen ; Zhang, Hailin ; Zhang, Linmeng ; Zhu, Andrew X. ; Bernards, René ; Qin, Wenxin ; Wang, Cun
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Gastroenterology & hepatology, 2023-04, Vol.20 (4), p.203-222
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Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial
Author / Creator:Rini, Brian I ; Powles, Thomas ; Atkins, Michael B ; Escudier, Bernard ; McDermott, David F ; Suarez, Cristina ; Bracarda, Sergio ; Stadler, Walter M ; Donskov, Frede ; Lee, Jae Lyun ; Hawkins, Robert ; Ravaud, Alain ; Alekseev, Boris ; Staehler, Michael ; Uemura, Motohide ; De Giorgi, Ugo ; Mellado, Begoña ; Porta, Camillo ; Melichar, Bohuslav ; Gurney, Howard ; Bedke, Jens ; Choueiri, Toni K ; Parnis, Francis ; Khaznadar, Tarik ; Thobhani, Alpa ; Li, Shi ; Piault-Louis, Elisabeth ; Frantz, Gretchen ; Huseni, Mahrukh ; Schiff, Christina ; Green, Marjorie C ; Motzer, Robert J
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2019-06, Vol.393 (10189), p.2404-2415
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Management of Glioblastoma: State of the Art and Future Directions
Author / Creator:Tan, Aaron C ; Ashley, David M ; López, Giselle Y ; Malinzak, Michael ; Friedman, Henry S ; Khasraw, Mustafa
Publisher:Atlanta: Wiley Subscription Services, Inc
Journal title:CA: a cancer journal for clinicians, 2020-07, Vol.70 (4), p.299
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Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer
Author / Creator:Prager, Gerald W. ; Taieb, Julien ; Fakih, Marwan ; Ciardiello, Fortunato ; Van Cutsem, Eric ; Elez, Elena ; Cruz, Felipe M. ; Wyrwicz, Lucjan ; Stroyakovskiy, Daniil ; Pápai, Zsuzsanna ; Poureau, Pierre-Guillaume ; Liposits, Gabor ; Cremolini, Chiara ; Bondarenko, Igor ; Modest, Dominik P. ; Benhadji, Karim A. ; Amellal, Nadia ; Leger, Catherine ; Vidot, Loïck ; Tabernero, Josep
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-05, Vol.388 (18), p.1657-1667
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Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic Oncology Group 240)
Author / Creator:Tewari, Krishnansu S ; Sill, Michael W ; Penson, Richard T ; Huang, Helen ; Ramondetta, Lois M ; Landrum, Lisa M ; Oaknin, Ana ; Reid, Thomas J ; Leitao, Mario M ; Michael, Helen E ; DiSaia, Philip J ; Copeland, Larry J ; Creasman, William T ; Stehman, Frederick B ; Brady, Mark F ; Burger, Robert A ; Thigpen, J Tate ; Birrer, Michael J ; Waggoner, Steven E ; Moore, David H ; Look, Katherine Y ; Koh, Wui-Jin ; Monk, Bradley J
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-10, Vol.390 (10103), p.1654-1663
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ArticlesPeer ReviewedFull Text
Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma
Author / Creator:McDermott, David F. ; Huseni, Mahrukh A. ; Atkins, Michael B. ; Motzer, Robert J. ; Rini, Brian I. ; Escudier, Bernard ; Fong, Lawrence ; Joseph, Richard W. ; Pal, Sumanta K. ; Reeves, James A. ; Sznol, Mario ; Hainsworth, John ; Rathmell, W. Kimryn ; Stadler, Walter M. ; Hutson, Thomas ; Gore, Martin E. ; Ravaud, Alain ; Bracarda, Sergio ; Suárez, Cristina ; Danielli, Riccardo ; Gruenwald, Viktor ; Choueiri, Toni K. ; Nickles, Dorothee ; Jhunjhunwala, Suchit ; Piault-Louis, Elisabeth ; Thobhani, Alpa ; Qiu, Jiaheng ; Chen, Daniel S. ; Hegde, Priti S. ; Schiff, Christina ; Fine, Gregg D. ; Powles, Thomas
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-06, Vol.24 (6), p.749-757
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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...
Author / Creator:Cremolini, Chiara, MD ; Loupakis, Fotios, PhD ; Antoniotti, Carlotta, MD ; Lupi, Cristiana, BSc ; Sensi, Elisa, PhD ; Lonardi, Sara, MD ; Mezi, Silvia, MD ; Tomasello, Gianluca, MD ; Ronzoni, Monica, MD ; Zaniboni, Alberto, MD ; Tonini, Giuseppe, Prof ; Carlomagno, Chiara, PhD ; Allegrini, Giacomo, MD ; Chiara, Silvana, MD ; D'Amico, Mauro, MD ; Granetto, Cristina, MD ; Cazzaniga, Marina, MD ; Boni, Luca, MD ; Fontanini, Gabriella, Prof ; Falcone, Alfredo, Prof
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2015-10, Vol.16 (13), p.1306-1315
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Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma
Author / Creator:Wallin, Jeffrey J. ; Bendell, Johanna C. ; Funke, Roel ; Sznol, Mario ; Korski, Konstanty ; Jones, Suzanne ; Hernandez, Genevive ; Mier, James ; He, Xian ; Hodi, F. Stephen ; Denker, Mitchell ; Leveque, Vincent ; Cañamero, Marta ; Babitski, Galina ; Koeppen, Hartmut ; Ziai, James ; Sharma, Neeraj ; Gaire, Fabien ; Chen, Daniel S. ; Waterkamp, Daniel ; Hegde, Priti S. ; McDermott, David F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-08, Vol.7 (1), p.12624-12624, Article 12624
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Efficacy and tolerability of bevacizumab in patients with severe Covid-19
Author / Creator:Pang, Jiaojiao ; Xu, Feng ; Aondio, Gianmarco ; Li, Yu ; Fumagalli, Alberto ; Lu, Ming ; Valmadre, Giuseppe ; Wei, Jie ; Bian, Yuan ; Canesi, Margherita ; Damiani, Giovanni ; Zhang, Yuan ; Yu, Dexin ; Chen, Jun ; Ji, Xiang ; Sui, Wenhai ; Wang, Bailu ; Wu, Shuo ; Kovacs, Attila ; Revera, Miriam ; Wang, Hao ; Jing, Xu ; Zhang, Ying ; Chen, Yuguo ; Cao, Yihai
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.814-814, Article 814
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Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab–bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study
Author / Creator:Zeng, Qinghe, MSc ; Klein, Christophe, MSc ; Caruso, Stefano, PhD ; Maille, Pascale, MSc ; Allende, Daniela S, MD ; Mínguez, Beatriz, MD ; Iavarone, Massimo, MD ; Ningarhari, Massih, PhD ; Casadei-Gardini, Andrea, MD ; Pedica, Federica, Prof ; Rimini, Margherita, MD ; Perbellini, Riccardo, MD ; Boulagnon-Rombi, Camille, PhD ; Heurgué, Alexandra, MD ; Maggioni, Marco, MD ; Rela, Mohamed, Prof ; Vij, Mukul, MD ; Baulande, Sylvain, PhD ; Legoix, Patricia, MSc ; Lameiras, Sonia, MSc ; Bruges, Léa, MD ; Gnemmi, Viviane, PhD ; Nault, Jean-Charles, Prof ; Campani, Claudia, MD ; Rhee, Hyungjin, Prof ; Park, Young Nyun, Prof ; Iñarrairaegui, Mercedes, MD ; Garcia-Porrero, Guillermo, MD ; Argemi, Josepmaria, MD ; Sangro, Bruno, Prof ; D'Alessio, Antonio, MD ; Scheiner, Bernhard, MD ; Pinato, David James, MD ; Pinter, Matthias, MD ; Paradis, Valérie, Prof ; Beaufrère, Aurélie, MD ; Peter, Simon, PhD ; Rimassa, Lorenza, MD ; Di Tommaso, Luca, Prof ; Vogel, Arndt, Prof ; Michalak, Sophie, MD ; Boursier, Jérôme, Prof ; Loménie, Nicolas, PhD ; Ziol, Marianne, Prof ; Calderaro, Julien, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2023-12, Vol.24 (12), p.1411-1422
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Real-World Data for Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma: How Does Adherence to the IMbrave150 Trial Inclusion Criteria Impact Prognosis?
Author / Creator:Rimini, Margherita ; Persano, Mara ; Tada, Toshifumi ; Suda, Goki ; Shimose, Shigeo ; Kudo, Masatoshi ; Cheon, Jaekyung ; Finkelmeier, Fabian ; Lim, Ho Yeong ; Presa, José ; Masi, Gianluca ; Yoo, Changhoon ; Lonardi, Sara ; Piscaglia, Fabio ; Kumada, Takashi ; Sakamoto, Naoya ; Iwamoto, Hideki ; Aoki, Tomoko ; Chon, Hong Jae ; Himmelsbach, Vera ; Pressiani, Tiziana ; Montes, Margarida ; Vivaldi, Caterina ; Soldà, Caterina ; Hiraoka, Atsushi ; Sho, Takuya ; Niizeki, Takashi ; Nishida, Naoshi ; Steup, Christoph ; Hirooka, Masashi ; Kariyama, Kazuya ; Tani, Joji ; Atsukawa, Masanori ; Takaguchi, Koichi ; Itobayashi, Ei ; Fukunishi, Shinya ; Tsuji, Kunihiko ; Ishikawa, Toru ; Tajiri, Kazuto ; Ochi, Hironori ; Yasuda, Satoshi ; Toyoda, Hidenori ; Ogawa, Chikara ; Nishimura, Takashi ; Hatanaka, Takeshi ; Kakizaki, Satoru ; Shimada, Noritomo ; Kawata, Kazuhito ; Tada, Fujimasa ; Ohama, Hideko ; Nouso, Kazuhiro ; Morishita, Asahiro ; Tsutsui, Akemi ; Nagano, Takuya ; Itokawa, Norio ; Okubo, Tomomi ; Arai, Taeang ; Imai, Michitaka ; Kosaka, Hisashi ; Naganuma, Atsushi ; Koizumi, Yohei ; Nakamura, Shinichiro ; Kaibori, Masaki ; Iijima, Hiroko ; Hiasa, Yoichi ; Burgio, Valentina ; Rimassa, Lorenza ; Scartozzi, Mario ; Cascinu, Stefano ; Casadei-Gardini, Andrea
Publisher:Cham: Springer International Publishing
Journal title:Targeted oncology, 2023-03, Vol.18 (2), p.221-233
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FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial
Author / Creator:Heinemann, Volker ; von Weikersthal, Ludwig Fischer ; Decker, Thomas ; Kiani, Alexander ; Kaiser, Florian ; Al-Batran, Salah-Edin ; Heintges, Tobias ; Lerchenmüller, Christoph ; Kahl, Christoph ; Seipelt, Gernot ; Kullmann, Frank ; Moehler, Markus ; Scheithauer, Werner ; Held, Swantje ; Miller-Phillips, Lisa ; Modest, Dominik Paul ; Jung, Andreas ; Kirchner, Thomas ; Stintzing, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2021-02, Vol.124 (3), p.587-594
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Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases
Author / Creator:Frentzas, Sophia ; Simoneau, Eve ; Bridgeman, Victoria L ; Vermeulen, Peter B ; Foo, Shane ; Kostaras, Eleftherios ; Nathan, Mark R ; Wotherspoon, Andrew ; Gao, Zu-hua ; Shi, Yu ; Van den Eynden, Gert ; Daley, Frances ; Peckitt, Clare ; Tan, Xianming ; Salman, Ayat ; Lazaris, Anthoula ; Gazinska, Patrycja ; Berg, Tracy J ; Eltahir, Zak ; Ritsma, Laila ; van Rheenen, Jacco ; Khashper, Alla ; Brown, Gina ; Nyström, Hanna ; Sund, Malin ; Van Laere, Steven ; Loyer, Evelyne ; Dirix, Luc ; Cunningham, David ; Metrakos, Peter ; Reynolds, Andrew R
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2016-11, Vol.22 (11), p.1294-1302
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Visual acuity outcomes and anti-VEGF therapy intensity in diabetic macular oedema: a real-world analysis of 28 658 patient eyes
Author / Creator:Ciulla, Thomas A ; Pollack, John S ; Williams, David F
Publisher:England: BMJ Publishing Group LTD
Journal title:British journal of ophthalmology, 2021-02, Vol.105 (2), p.216-221
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PARP Inhibitors in Ovarian Cancer: A Review
Author / Creator:O’Malley, David M. ; Krivak, Thomas C. ; Kabil, Nashwa ; Munley, Jiefen ; Moore, Kathleen N.
Publisher:Cham: Springer International Publishing
Journal title:Targeted oncology, 2023-07, Vol.18 (4), p.471-503
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Adjuvant chemotherapy with or without bevacizumab in patients with resected non-small-cell lung cancer (E1505): an open-label, multicentre, randomised, phase 3 trial
Author / Creator:Wakelee, Heather A ; Dahlberg, Suzanne E ; Keller, Steven M ; Tester, William J ; Gandara, David R ; Graziano, Stephen L ; Adjei, Alex A ; Leighl, Natasha B ; Aisner, Seena C ; Rothman, Jan M ; Patel, Jyoti D ; Sborov, Mark D ; McDermott, Sean R ; Perez-Soler, Roman ; Traynor, Anne M ; Butts, Charles ; Evans, Tracey ; Shafqat, Atif ; Chapman, Andrew E ; Kasbari, Samer S ; Horn, Leora ; Ramalingam, Suresh S ; Schiller, Joan H
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-12, Vol.18 (12), p.1610-1623
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Current Targeted Therapy for Metastatic Colorectal Cancer
Author / Creator:Ohishi, Tomokazu ; Kaneko, Mika K. ; Yoshida, Yukihiro ; Takashima, Atsuo ; Kato, Yukinari ; Kawada, Manabu
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-01, Vol.24 (2), p.1702
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Impact of macular fluid volume fluctuations on visual acuity during anti-VEGF therapy in eyes with nAMD
Author / Creator:Chakravarthy, Usha ; Havilio, Moshe ; Syntosi, Annie ; Pillai, Natasha ; Wilkes, Emily ; Benyamini, Gidi ; Best, Catherine ; Sagkriotis, Alexandros
Publisher:London: Nature Publishing Group UK
Journal title:Eye (London), 2021-11, Vol.35 (11), p.2983-2990
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The role of bevacizumab in the treatment of glioblastoma
Author / Creator:Diaz, Roberto Jose ; Ali, Sheikh ; Qadir, Mehreen Gull ; De La Fuente, Macarena I. ; Ivan, Michael E. ; Komotar, Ricardo J.
Publisher:New York: Springer US
Journal title:Journal of neuro-oncology, 2017-07, Vol.133 (3), p.455-467
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Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial

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Evolving therapeutic landscape of advanced hepatocellular carcinoma

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Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial

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Management of Glioblastoma: State of the Art and Future Directions

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Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer

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Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic Oncology Group 240)

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Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma

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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...

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Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma

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Efficacy and tolerability of bevacizumab in patients with severe Covid-19

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Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab–bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study

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Real-World Data for Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma: How Does Adherence to the IMbrave150 Trial Inclusion Criteria Impact Prognosis?

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FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

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Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases

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Visual acuity outcomes and anti-VEGF therapy intensity in diabetic macular oedema: a real-world analysis of 28 658 patient eyes

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PARP Inhibitors in Ovarian Cancer: A Review

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Adjuvant chemotherapy with or without bevacizumab in patients with resected non-small-cell lung cancer (E1505): an open-label, multicentre, randomised, phase 3 trial

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Current Targeted Therapy for Metastatic Colorectal Cancer

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Impact of macular fluid volume fluctuations on visual acuity during anti-VEGF therapy in eyes with nAMD

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The role of bevacizumab in the treatment of glioblastoma

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