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Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4+ cells in vivo
Author / Creator:Wang, Zhaohui ; Wei, Min ; Zhang, Huiping ; Chen, Hongyuan ; Germana, Sharon ; Huang, Christene A. ; Madsen, Joren C. ; Sachs, David H. ; Wang, Zhirui
Publisher:United States: Elsevier B.V
Journal title:Molecular oncology, 2015-08, Vol.9 (7), p.1458-1470
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Anti-CCR4 mAb selectively depletes effector-type FoxP3⁺CD4⁺ regulatory T cells, evoking antitumor immune responses in humans
Author / Creator:Sugiyama, Daisuke ; Nishikawa, Hiroyoshi ; Maeda, Yuka ; Nishioka, Megumi ; Tanemura, Atsushi ; Katayama, Ichiro ; Ezoe, Sachiko ; Kanakura, Yuzuru ; Sato, Eiichi ; Fukumori, Yasuo ; Karbach, Julia ; Jäger, Elke ; Sakaguchi, Shimon
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17945-17950
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Dosing optimization of CCR4 immunotoxin for improved depletion of CCR4+ Treg in nonhuman primates
Author / Creator:Wang, Zhaohui ; Louras, Nathan J. ; Lellouch, Alexandre G. ; Pratts, Shannon G. ; Zhang, Huiping ; Wang, Haoyu ; Huang, Christene A. ; Cetrulo, Curtis L. ; Madsen, Joren C. ; Sachs, David H. ; Wang, Zhirui
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2018-08, Vol.12 (8), p.1374-1382
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Mogamulizumab (Anti-CCR4) in HTLV-1–Associated Myelopathy
Author / Creator:Sato, Tomoo ; Coler-Reilly, Ariella L.G ; Yagishita, Naoko ; Araya, Natsumi ; Inoue, Eisuke ; Furuta, Rie ; Watanabe, Toshiki ; Uchimaru, Kaoru ; Matsuoka, Masao ; Matsumoto, Naoki ; Hasegawa, Yasuhiro ; Yamano, Yoshihisa
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-02, Vol.378 (6), p.529-538
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CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4
Author / Creator:Korbecki, Jan ; Kojder, Klaudyna ; Simińska, Donata ; Bohatyrewicz, Romuald ; Gutowska, Izabela ; Chlubek, Dariusz ; Baranowska-Bosiacka, Irena
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-11, Vol.21 (21), p.8412
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CCR4 as a Therapeutic Target for Cancer Immunotherapy
Author / Creator:Yoshie, Osamu
Publisher:Basel: MDPI AG
Journal title:Cancers, 2021-11, Vol.13 (21), p.5542
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Tumors establish resistance to immunotherapy by regulating T reg recruitment via CCR4
Author / Creator:Marshall, Lisa A ; Marubayashi, Sachie ; Jorapur, Aparna ; Jacobson, Scott ; Zibinsky, Mikhail ; Robles, Omar ; Hu, Dennis Xiaozhou ; Jackson, Jeffrey J ; Pookot, Deepa ; Sanchez, Jerick ; Brovarney, Martin ; Wadsworth, Angela ; Chian, David ; Wustrow, David ; Kassner, Paul D ; Cutler, Gene ; Wong, Brian ; Brockstedt, Dirk G ; Talay, Oezcan
Publisher:England
Journal title:Journal for immunotherapy of cancer, 2020-11, Vol.8 (2), p.e000764
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Trametinib improves Treg selectivity of anti-CCR4 antibody by regulating CCR4 expression in CTLs in oral squamous cell carcinoma
Author / Creator:Ono, Shoya ; Suzuki, Susumu ; Kondo, Yutaro ; Okubo, Ikuko ; Goto, Mitsuo ; Ogawa, Tetsuya ; Kato, Hidefumi ; Ito, Hideaki ; Takahara, Taishi ; Satou, Akira ; Tsuzuki, Toyonori ; Yoshikawa, Kazuhiro ; Nagao, Toru ; Ueda, Ryuzo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-12, Vol.12 (1), p.21678-21678, Article 21678
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Mogamulizumab, an Anti-CCR4 Antibody, Targets Human T-Lymphotropic Virus Type 1-infected CD8⁺ and CD4⁺ T Cells to Treat Associated Myelopathy
Author / Creator:Yamauchi, Junji ; Coler-Reilly, Ariella ; Sato, Tomoo ; Araya, Natsumi ; Yagishita, Naoko ; Ando, Hitoshi ; Kunitomo, Yasuo ; Takahashi, Katsunori ; Tanaka, Yuetsu ; Shibagaki, Yugo ; Nishioka, Kusuki ; Nakajima, Toshihiro ; Hasegawa, Yasuhiro ; Utsunomiya, Atae ; Kimura, Kenjiro ; Yamano, Yoshihisa
Publisher:United States: Oxford University Press
Journal title:The Journal of infectious diseases, 2015-01, Vol.211 (2), p.238-248
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CCL17/CCR4 Axis Promotes Hematoma Clearance via ERK/AP1/SRA‐Mediated Microglial Polarization After Intracerebral Hemorrhage
Author / Creator:Chen, Xianglan ; Wang, Yao ; Jin, Junjie ; Jin, Peng ; Deng, Shuixiang
Publisher:England: John Wiley & Sons, Inc
Journal title:CNS neuroscience & therapeutics, 2025-02, Vol.31 (2), p.e70288-n/a
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Novel interaction between CCR4 and CAF1 in rice CCR4–NOT deadenylase complex
Author / Creator:Chou, Wei-Lun ; Chung, Yue-Lin ; Fang, Jhen-Cheng ; Lu, Chung-An
Publisher:Dordrecht: Springer Netherlands
Journal title:Plant molecular biology, 2017-01, Vol.93 (1-2), p.79-96
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Targeting Monocyte Derived CCL17 Attenuates Murine Crescentic Glomerulonephritis by Affecting Renal CCR4+ Regulatory T-Cell Recruitment
Author / Creator:Song, Ning ; Paust, Hans-Joachim ; Asada, Nariaki ; Peters, Anett ; Kaffke, Anna ; Krebs, Christian F. ; Panzer, Ulf ; Riedel, Jan-Hendrik
Publisher:Basel, Switzerland: S. Karger AG
Journal title:American journal of nephrology, 2024-04, Vol.55 (2), p.214-224
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HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells
Author / Creator:Araya, Natsumi ; Sato, Tomoo ; Ando, Hitoshi ; Tomaru, Utano ; Yoshida, Mari ; Coler-Reilly, Ariella ; Yagishita, Naoko ; Yamauchi, Junji ; Hasegawa, Atsuhiko ; Kannagi, Mari ; Hasegawa, Yasuhiro ; Takahashi, Katsunori ; Kunitomo, Yasuo ; Tanaka, Yuetsu ; Nakajima, Toshihiro ; Nishioka, Kusuki ; Utsunomiya, Atae ; Jacobson, Steven ; Yamano, Yoshihisa
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-08, Vol.124 (8), p.3431-3442
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Immunohistochemistry for CCR4 C‐terminus predicts CCR4 mutations and mogamulizumab efficacy in adult T‐cell leukemia/lymphoma
Author / Creator:Fujii, Keiichiro ; Sakamoto, Yuma ; Masaki, Ayako ; Murase, Takayuki ; Tashiro, Yukie ; Yonekura, Kentaro ; Utsunomiya, Atae ; Ito, Asahi ; Kusumoto, Shigeru ; Iida, Shinsuke ; Ueda, Ryuzo ; Ishida, Takashi ; Inagaki, Hiroshi
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:The journal of pathology. Clinical research, 2021-01, Vol.7 (1), p.52-60
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The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity
Author / Creator:Scheu, Stefanie ; Ali, Shafaqat ; Ruland, Christina ; Arolt, Volker ; Alferink, Judith
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-11, Vol.18 (11), p.2306
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A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer
Author / Creator:Berlato, Chiara ; Khan, Moddasar N. ; Schioppa, Tiziana ; Thompson, Richard ; Maniati, Eleni ; Montfort, Anne ; Jangani, Maryam ; Canosa, Monica ; Kulbe, Hagen ; Hagemann, Urs B. ; Duncan, Alexander R. ; Fletcher, Laura ; Wilkinson, Robert W. ; Powles, Thomas ; Quezada, Sergio A. ; Balkwill, Frances R.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-03, Vol.127 (3), p.801-813
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Retraction Note: CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling
Author / Creator:Al-haidari, Amr A. ; Syk, Ingvar ; Jirström, Karin ; Thorlacius, Henrik
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:International journal of colorectal disease, 2023-06, Vol.38 (1), p.165-165, Article 165
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Ischemic stroke outcome after promoting CD4+CD25+ Treg cell migration through CCR4 overexpression in a tMCAO animal model
Author / Creator:Lee, Seowoo ; Kim, Jiwon ; You, Je Sung ; Hyun, Young-Min ; Kim, Jong Youl ; Lee, Jong Eun
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-05, Vol.14 (1), p.10201-10201, Article 10201
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Skin-resident dendritic cells mediate postoperative pain via CCR4 on sensory neurons
Author / Creator:Silva, Jaqueline Raymondi ; Iftinca, Mircea ; Gomes, Francisco I. Fernandes ; Segal, Julia P. ; Smith, Olivia M. A. ; Bannerman, Courtney A. ; Mendes, Atlante Silva ; Defaye, Manon ; Robinson, Madeline E. C. ; Gilron, Ian ; Cunha, Thiago Mattar ; Altier, Christophe ; Ghasemloua, Nader
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (4), p.1-10
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CC Chemokine Receptor 4 (CCR4) as a Possible New Target for Therapy
Author / Creator:Bogacka, Joanna ; Pawlik, Katarzyna ; Ciapała, Katarzyna ; Ciechanowska, Agata ; Mika, Joanna
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-12, Vol.23 (24), p.15638
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Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4+ cells in vivo

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Anti-CCR4 mAb selectively depletes effector-type FoxP3⁺CD4⁺ regulatory T cells, evoking antitumor immune responses in humans

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Dosing optimization of CCR4 immunotoxin for improved depletion of CCR4+ Treg in nonhuman primates

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Mogamulizumab (Anti-CCR4) in HTLV-1–Associated Myelopathy

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CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4

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CCR4 as a Therapeutic Target for Cancer Immunotherapy

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Tumors establish resistance to immunotherapy by regulating T reg recruitment via CCR4

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Trametinib improves Treg selectivity of anti-CCR4 antibody by regulating CCR4 expression in CTLs in oral squamous cell carcinoma

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Mogamulizumab, an Anti-CCR4 Antibody, Targets Human T-Lymphotropic Virus Type 1-infected CD8⁺ and CD4⁺ T Cells to Treat Associated Myelopathy

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CCL17/CCR4 Axis Promotes Hematoma Clearance via ERK/AP1/SRA‐Mediated Microglial Polarization After Intracerebral Hemorrhage

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Novel interaction between CCR4 and CAF1 in rice CCR4–NOT deadenylase complex

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Targeting Monocyte Derived CCL17 Attenuates Murine Crescentic Glomerulonephritis by Affecting Renal CCR4+ Regulatory T-Cell Recruitment

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HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

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Immunohistochemistry for CCR4 C‐terminus predicts CCR4 mutations and mogamulizumab efficacy in adult T‐cell leukemia/lymphoma

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The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity

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A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

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Retraction Note: CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling

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Ischemic stroke outcome after promoting CD4+CD25+ Treg cell migration through CCR4 overexpression in a tMCAO animal model

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Skin-resident dendritic cells mediate postoperative pain via CCR4 on sensory neurons

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CC Chemokine Receptor 4 (CCR4) as a Possible New Target for Therapy

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