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34 results for Cannabinoid+Receptor+Agonists+-+chemistry

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ArticlesPeer ReviewedFull Text
Crystal structures of agonist-bound human cannabinoid receptor CB 1
Author / Creator:Hua, Tian ; Vemuri, Kiran ; Nikas, Spyros P ; Laprairie, Robert B ; Wu, Yiran ; Qu, Lu ; Pu, Mengchen ; Korde, Anisha ; Jiang, Shan ; Ho, Jo-Hao ; Han, Gye Won ; Ding, Kang ; Li, Xuanxuan ; Liu, Haiguang ; Hanson, Michael A ; Zhao, Suwen ; Bohn, Laura M ; Makriyannis, Alexandros ; Stevens, Raymond C ; Liu, Zhi-Jie
Publisher:England
Journal title:Nature (London), 2017-07, Vol.547 (7664), p.468
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Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products
Author / Creator:An, Dongchen ; Peigneur, Steve ; Hendrickx, Louise Antonia ; Tytgat, Jan
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-07, Vol.21 (14), p.5064
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A Guide to Targeting the Endocannabinoid System in Drug Design
Author / Creator:Stasiulewicz, Adam ; Znajdek, Katarzyna ; Grudzień, Monika ; Pawiński, Tomasz ; Sulkowska, And Joanna I
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-04, Vol.21 (8), p.2778
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CB1 Cannabinoid Receptor Signaling and Biased Signaling
Author / Creator:Leo, Luciana M ; Abood, Mary E
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-09, Vol.26 (17), p.5413
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Cannabimimetic plants: are they new cannabinoidergic modulators?
Author / Creator:Kumar, Amit ; Premoli, Marika ; Aria, Francesca ; Bonini, Sara Anna ; Maccarinelli, Giuseppina ; Gianoncelli, Alessandra ; Memo, Maurizio ; Mastinu, Andrea
Publisher:Berlin/Heidelberg: Springer Science + Business Media
Journal title:Planta, 2019-06, Vol.249 (6), p.1681-1694
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Cannabidiol binding and negative allosteric modulation at the cannabinoid type 1 receptor in the presence of delta-9-tetrahydrocannabinol: An In Silico study
Author / Creator:Chung, Hery ; Fierro, Angélica ; Pessoa-Mahana, C David
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-07, Vol.14 (7), p.e0220025-e0220025
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Structure-activity relationships for 5F-MDMB-PICA and its 5F-pentylindole analogs to induce cannabinoid-like effects in mice
Author / Creator:Glatfelter, Grant C ; Partilla, John S ; Baumann, Michael H
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2022-03, Vol.47 (4), p.924-932
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Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB 2 receptor
Author / Creator:Patel, Monica ; Grimsey, Natasha L ; Banister, Samuel D ; Finlay, David B ; Glass, Michelle
Publisher:United States
Journal title:Pharmacology research & perspectives, 2023-12, Vol.11 (6), p.e01157
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Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects
Author / Creator:Tummino, Tia A. ; Iliopoulos-Tsoutsouvas, Christos ; Braz, Joao M. ; O’Brien, Evan S. ; Stein, Reed M. ; Craik, Veronica ; Tran, Ngan K. ; Ganapathy, Suthakar ; Liu, Fangyu ; Shiimura, Yuki ; Tong, Fei ; Ho, Thanh C. ; Radchenko, Dmytro S. ; Moroz, Yurii S. ; Rosado, Sian Rodriguez ; Bhardwaj, Karnika ; Benitez, Jorge ; Liu, Yongfeng ; Kandasamy, Herthana ; Normand, Claire ; Semache, Meriem ; Sabbagh, Laurent ; Glenn, Isabella ; Irwin, John J. ; Kumar, Kaavya Krishna ; Makriyannis, Alexandros ; Basbaum, Allan I. ; Shoichet, Brian K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2237-19
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Terpenoids, Cannabimimetic Ligands, beyond the Cannabis Plant
Author / Creator:Gonçalves, Elaine C D ; Baldasso, Gabriela M ; Bicca, Maíra A ; Paes, Rodrigo S ; Capasso, Raffaele ; Dutra, Rafael C
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-03, Vol.25 (7), p.1567
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Assessment of select synthetic cannabinoid receptor agonist bias and selectivity between the type 1 and type 2 cannabinoid receptor
Author / Creator:Zagzoog, Ayat ; Brandt, Asher L. ; Black, Tallan ; Kim, Eunhyun D. ; Burkart, Riley ; Patel, Mikin ; Jin, Zhiyun ; Nikolaeva, Maria ; Laprairie, Robert B.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-05, Vol.11 (1), p.10611-18, Article 10611
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CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency
Author / Creator:Smoum, Reem ; Baraghithy, Saja ; Chourasia, Mukesh ; Breuer, Aviva ; Mussai, Naama ; Attar-Namdar, Malka ; Kogan, Natalya M. ; Raphael, Bitya ; Bolognini, Daniele ; Cascio, Maria G. ; Marini, Pietro ; Pertwee, Roger G. ; Shurki, Avital ; Mechoulam, Raphael ; Bab, Itai
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (28), p.8774-8779
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Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists
Author / Creator:Omar, Abdelsattar M ; Aljahdali, Anfal S ; Safo, Martin K ; Mohamed, Gamal A ; Ibrahim, Sabrin R M
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.44
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In vitro characterization of the pyrazole-carrying synthetic cannabinoid receptor agonist 5F-3,5-AB-PFUPPYCA and its structural analogs
Author / Creator:Deventer, Marie H. ; Norman, Caitlyn ; Reid, Robert ; McKenzie, Craig ; Nic Daéid, Niamh ; Stove, Christophe P.
Publisher:Ireland: Elsevier B.V
Journal title:Forensic science international, 2023-02, Vol.343, p.111565, Article 111565
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Translational potential of allosteric modulators targeting the cannabinoid CB 1 receptor
Author / Creator:Lu, Dai ; Immadi, Sri Sujana ; Wu, Zhixing ; Kendall, Debra A
Publisher:United States
Journal title:Acta pharmacologica Sinica, 2019-03, Vol.40 (3), p.324
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N -[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Dea...
Author / Creator:Gianquinto, Eleonora ; Sodano, Federica ; Rolando, Barbara ; Kostrzewa, Magdalena ; Allarà, Marco ; Mahmoud, Ali Mokhtar ; Kumar, Poulami ; Spyrakis, Francesca ; Ligresti, Alessia ; Chegaev, Konstantin
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-11, Vol.27 (23), p.8152
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Structure-Based Virtual Screening and Molecular Dynamics Simulation Assessments of Depsidones as Possible Selective Cannabinoid Receptor Type 2 Agonists
Author / Creator:Mohamed, Gamal A ; Omar, Abdelsattar M ; AlKharboush, Dana F ; Fallatah, Mona A ; Sindi, Ikhlas A ; El-Agamy, Dina S ; Ibrahim, Sabrin R M
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1761
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“Spice”-related deaths in and around Munich, Germany: A retrospective look at the role of synthetic cannabinoid receptor agonists in our post-mortem cases over a seven-year period (2014–2020)
Author / Creator:Groth, Olwen ; Roider, Gabriele ; Angerer, Verena ; Schäper, Jan ; Graw, Matthias ; Musshoff, Frank ; Auwärter, Volker
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:International journal of legal medicine, 2023-07, Vol.137 (4), p.1059-1069
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Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells
Author / Creator:Gado, Francesca ; Ferrisi, Rebecca ; Di Somma, Sarah ; Napolitano, Fabiana ; Mohamed, Kawthar A ; Stevenson, Lesley A ; Rapposelli, Simona ; Saccomanni, Giuseppe ; Portella, Giuseppe ; Pertwee, Roger G ; Laprairie, Robert B ; Malfitano, Anna Maria ; Manera, Clementina
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-05, Vol.27 (9), p.3019
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Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells
Author / Creator:Capozzi, Antonella ; Caissutti, Daniela ; Mattei, Vincenzo ; Gado, Francesca ; Martellucci, Stefano ; Longo, Agostina ; Recalchi, Serena ; Manganelli, Valeria ; Riitano, Gloria ; Garofalo, Tina ; Sorice, Maurizio ; Manera, Clementina ; Misasi, Roberta
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-12, Vol.27 (1), p.64
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Crystal structures of agonist-bound human cannabinoid receptor CB 1

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Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products

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A Guide to Targeting the Endocannabinoid System in Drug Design

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CB1 Cannabinoid Receptor Signaling and Biased Signaling

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Cannabimimetic plants: are they new cannabinoidergic modulators?

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Cannabidiol binding and negative allosteric modulation at the cannabinoid type 1 receptor in the presence of delta-9-tetrahydrocannabinol: An In Silico study

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Structure-activity relationships for 5F-MDMB-PICA and its 5F-pentylindole analogs to induce cannabinoid-like effects in mice

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Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB 2 receptor

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Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects

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Terpenoids, Cannabimimetic Ligands, beyond the Cannabis Plant

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Assessment of select synthetic cannabinoid receptor agonist bias and selectivity between the type 1 and type 2 cannabinoid receptor

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CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency

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Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists

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In vitro characterization of the pyrazole-carrying synthetic cannabinoid receptor agonist 5F-3,5-AB-PFUPPYCA and its structural analogs

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Translational potential of allosteric modulators targeting the cannabinoid CB 1 receptor

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N -[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Dea...

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Structure-Based Virtual Screening and Molecular Dynamics Simulation Assessments of Depsidones as Possible Selective Cannabinoid Receptor Type 2 Agonists

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“Spice”-related deaths in and around Munich, Germany: A retrospective look at the role of synthetic cannabinoid receptor agonists in our post-mortem cases over a seven-year period (2014–2020)

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Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells

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Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells

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