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ArticlesPeer ReviewedFull Text
Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling
Author / Creator:Liss, Martin ; Radke, Michael H. ; Eckhard, Jamina ; Neuenschwander, Martin ; Dauksaite, Vita ; von Kries, Jens-Peter ; Gotthardt, Michael
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-06, Vol.13 (6), p.e0198492-e0198492
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Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450
Author / Creator:Cerella, C ; Muller, F ; Gaigneaux, A ; Radogna, F ; Viry, E ; Chateauvieux, S ; Dicato, M ; Diederich, M
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2015-06, Vol.6 (6), p.e1782-e1782
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Predictability in the evolution of Orthopteran cardenolide insensitivity
Author / Creator:Yang, Lu ; Ravikanthachari, Nitin ; Mariño-Pérez, Ricardo ; Deshmukh, Riddhi ; Wu, Mariana ; Rosenstein, Adam ; Kunte, Krushnamegh ; Song, Hojun ; Andolfatto, Peter
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2019-07, Vol.374 (1777), p.20180246-20180246
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New Structures, Spectrometric Quantification, and Inhibitory Properties of Cardenolides from Asclepias curassavica Seeds
Author / Creator:Rubiano-Buitrago, Paola ; Pradhan, Shrikant ; Paetz, Christian ; Rowland, Hannah M.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.105
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Pro-Apoptotic and Pro-Autophagic Properties of Cardenolides from Aerial Parts of Pergularia tomentosa
Author / Creator:Martucciello, Stefania ; Paolella, Gaetana ; Romanelli, Antonio Massimiliano ; Sposito, Silvia ; Meola, Lucia ; Cerulli, Antonietta ; Masullo, Milena ; Piacente, Sonia ; Caputo, Ivana
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-07, Vol.27 (15), p.4874
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Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigms
Author / Creator:Eid, Shehab ; Zhao, Wenda ; Williams, Declan ; Nasser, Zahra ; Griffin, Jennifer ; Nagorny, Pavel ; Schmitt-Ulms, Gerold
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-09, Vol.19 (9), p.e0308821
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Identification of steroidal cardenolides from Calotropis procera as novel HIV-1 PR inhibitors: A molecular docking & molecular dynamics simulation study
Author / Creator:Swapna, Kandagatla ; Srujana, M. ; Mamidala, Estari
Publisher:India: Scientific Scholar
Journal title:Indian journal of medical research (New Delhi, India : 1994), 2024-07, Vol.160 (1), p.78-86, Article 78
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Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma
Author / Creator:Radogna, F ; Cerella, C ; Gaigneaux, A ; Christov, C ; Dicato, M ; Diederich, M
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2016-07, Vol.35 (29), p.3839-3853
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Elucidation of the mechanism of anti-herpes action of two novel semisynthetic cardenolide derivatives
Author / Creator:Boff, Laurita ; Schneider, Naira Fernanda Zanchett ; Munkert, Jennifer ; Ottoni, Flaviano Melo ; Ramos, Gabriela Silva ; Kreis, Wolfgang ; Braga, Fernão Castro ; Alves, Ricardo José ; de Pádua, Rodrigo Maia ; Simões, Cláudia Maria Oliveira
Publisher:Austria: Springer Nature B.V
Journal title:Archives of virology, 2020-06, Vol.165 (6), p.1385-1396
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Cytotoxicity of Oleandrin Is Mediated by Calcium Influx and by Increased Manganese Uptake in Saccharomyces cerevisiae Cells
Author / Creator:Ruta, Lavinia L. ; Popa, Claudia V. ; Farcasanu, Ileana C.
Publisher:Switzerland: MDPI
Journal title:Molecules (Basel, Switzerland), 2020-09, Vol.25 (18), p.4259
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The cardiac glycoside oleandrin induces apoptosis in human colon cancer cells via the mitochondrial pathway
Author / Creator:Pan, Li ; Zhang, Yuming ; Zhao, Wanlu ; Zhou, Xia ; Wang, Chunxia ; Deng, Fan
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2017-07, Vol.80 (1), p.91-100
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Semisynthetic Cardenolides Acting as Antiviral Inhibitors of Influenza A Virus Replication by Preventing Polymerase Complex Formation
Author / Creator:Boff, Laurita ; Schreiber, André ; da Rocha Matos, Aline ; Del Sarto, Juliana ; Brunotte, Linda ; Munkert, Jennifer ; Melo Ottoni, Flaviano ; Silva Ramos, Gabriela ; Kreis, Wolfgang ; Castro Braga, Fernão ; José Alves, Ricardo ; Maia de Pádua, Rodrigo ; Maria Oliveira Simões, Cláudia ; Ludwig, Stephan
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-10, Vol.25 (20), p.4853
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ArticlesPeer ReviewedFull Text
Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na+,K+-ATPase and ion channels on lung cancer cells
Author / Creator:Schneider, Naira Fernanda Zanchett ; Menegaz, Danusa ; Dagostin, Andre Luiz Andreotti ; Persich, Lara ; Rocha, Sayonarah C. ; Ramos, Ana Carolina Pacheco ; Cortes, Vanessa Faria ; Fontes, Carlos Frederico Leite ; de Pádua, Rodrigo Maia ; Munkert, Jennifer ; Kreis, Wolfgang ; Braga, Fernão Castro ; Barbosa, Leandro A. ; Silva, Fátima Regina Mena Barreto ; Simões, Cláudia Maria Oliveira
Publisher:New York: Springer US
Journal title:Molecular and cellular biochemistry, 2021-04, Vol.476 (4), p.1825-1848
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ArticlesPeer ReviewedFull Text
Calotropin and corotoxigenin 3-O-glucopyranoside from the desert milkweed Asclepias subulata inhibit the Na + /K + -ATPase activity
Author / Creator:Meneses-Sagrero, Salvador E. ; Rascón-Valenzuela, Luisa A. ; García-Ramos, Juan C. ; Vilegas, Wagner ; Arvizu-Flores, Aldo A. ; Sotelo-Mundo, Rogerio R. ; Robles-Zepeda, Ramon E.
Publisher:United States: PeerJ, Inc
Journal title:PeerJ (San Francisco, CA), 2022-06, Vol.10, p.e13524-e13524, Article e13524
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ArticlesPeer ReviewedFull Text
Negative regulation of thyroid adenoma-associated protein (THADA) in the cardiac glycoside-induced anti-cancer effect
Author / Creator:Katoh, Mizuki ; Fujii, Takuto ; Tabuchi, Yoshiaki ; Shimizu, Takahiro ; Sakai, Hideki
Publisher:Japan
Journal title:The journal of physiological sciences, 2024, Vol.74 (1), p.23
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Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway
Author / Creator:Ma, Yunlong ; Zhu, Bin ; Liu, Xiaoguang ; Yu, Huilei ; Yong, Lei ; Liu, Xiao ; Shao, Jia ; Liu, Zhongjun
Publisher:England: BioMed Central
Journal title:Journal of experimental & clinical cancer research, 2015-10, Vol.34, p.115-115
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Efficacy of oleandrin and PBI-05204 against bovine viruses of importance to commercial cattle health
Author / Creator:Newman, Robert A. ; Chase, Christopher C.L. ; Matos, Jose R. ; Abdelsalam, Karim ; Buterbaugh, Robin ; Van Holland, Sonja ; Abdelaal, Hadia ; Woolum, Amelia ; Jagannadha Sastry, K
Publisher:London, England: SAGE Publications
Journal title:Antiviral chemistry & chemotherapy, 2022, Vol.30, p.204020662211039-20402066221103960
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Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery
Author / Creator:Li, Hairi ; Zhou, Hongyan ; Wang, Dong ; Qiu, Jinsong ; Zhou, Yu ; Li, Xiangqiang ; Rosenfeld, Michael G ; Ding, Sheng ; Fu, Xiang-Dong
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4609-4614
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TARGETING THE α 1 SUBUNIT OF THE SODIUM PUMP TO COMBAT GLIOBLASTOMA CELLS
Author / Creator:Lefranc, Florence ; Mijatovic, Tatjana ; Kondo, Yasuko ; Sauvage, Sébastien ; Roland, Isabelle ; Debeir, Olivier ; Krstic, Danijela ; Vasic, Vesna ; Gailly, Philippe ; Kondo, Seiji ; Blanco, Gustavo ; Kiss, Robert
Publisher:United States: Wolters Kluwer Health, Inc
Journal title:Neurosurgery, 2008-01, Vol.62 (1), p.211-222
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Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment
Author / Creator:Ma, Yunlong ; Zhu, Bin ; Yong, Lei ; Song, Chunyu ; Liu, Xiao ; Yu, Huilei ; Wang, Peng ; Liu, Zhongjun ; Liu, Xiaoguang
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2016-11, Vol.17 (11), p.1950-1950
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Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

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Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450

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Predictability in the evolution of Orthopteran cardenolide insensitivity

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New Structures, Spectrometric Quantification, and Inhibitory Properties of Cardenolides from Asclepias curassavica Seeds

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Pro-Apoptotic and Pro-Autophagic Properties of Cardenolides from Aerial Parts of Pergularia tomentosa

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Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigms

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Identification of steroidal cardenolides from Calotropis procera as novel HIV-1 PR inhibitors: A molecular docking & molecular dynamics simulation study

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Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma

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Elucidation of the mechanism of anti-herpes action of two novel semisynthetic cardenolide derivatives

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Cytotoxicity of Oleandrin Is Mediated by Calcium Influx and by Increased Manganese Uptake in Saccharomyces cerevisiae Cells

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The cardiac glycoside oleandrin induces apoptosis in human colon cancer cells via the mitochondrial pathway

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Semisynthetic Cardenolides Acting as Antiviral Inhibitors of Influenza A Virus Replication by Preventing Polymerase Complex Formation

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Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na+,K+-ATPase and ion channels on lung cancer cells

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Calotropin and corotoxigenin 3-O-glucopyranoside from the desert milkweed Asclepias subulata inhibit the Na + /K + -ATPase activity

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Negative regulation of thyroid adenoma-associated protein (THADA) in the cardiac glycoside-induced anti-cancer effect

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Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway

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Efficacy of oleandrin and PBI-05204 against bovine viruses of importance to commercial cattle health

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Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery

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TARGETING THE α 1 SUBUNIT OF THE SODIUM PUMP TO COMBAT GLIOBLASTOMA CELLS

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Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment

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