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CARIDHA, DIANA awarded government contract
Publisher:Washington: Federal Information & News Dispatch, LLC
Journal title:U.S. Department of Defense Information / FIND, 2018
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ArticlesPeer ReviewedFull Text
The metabolism of primaquine to its active metabolite is dependent on CYP 2D6
Author / Creator:Pybus, Brandon S ; Marcsisin, Sean R ; Jin, Xiannu ; Deye, Gregory ; Sousa, Jason C ; Li, Qigui ; Caridha, Diana ; Zeng, Qiang ; Reichard, Gregory A ; Ockenhouse, Christian ; Bennett, Jason ; Walker, Larry A ; Ohrt, Colin ; Melendez, Victor
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2013-06, Vol.12 (1), p.212-212, Article 212
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Direct Comparison of the Efficacy and Safety of Oral Treatments with Oleylphosphocholine (OlPC) and Miltefosine in a Mouse Model of L. major Cutaneous Leishmaniasis
Author / Creator:Fortin, Anny ; Caridha, Diana P. ; Leed, Susan ; Ngundam, Franklyn ; Sena, Jenell ; Bosschaerts, Tom ; Parriott, Sandi ; Hickman, Mark R. ; Hudson, Thomas H. ; Grogl, Max
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2014-09, Vol.8 (9), p.e3144
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ArticlesPeer ReviewedFull Text
Plerixafor for pathogen‐agnostic treatment in murine thigh infection and zebrafish sepsis
Author / Creator:Evans, Martin O. ; Smith, Darren M. ; Kress, Adrian T. ; Nadeau, Robert J. ; Selig, Daniel J. ; Caridha, Diana ; Racharaks, Ratanachat ; Langowski, Thomas ; Madejczyk, Michael S. ; Carbaugh, Chance ; Saunders, David ; Widder, Mark ; De Meese, Jason ; Lee, Patricia J. ; DeLuca, Jesse P.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2024-07, Vol.17 (7), p.e13876-n/a
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Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria
Author / Creator:Caridha, Diana ; Hickman, Mark ; Xie, Lisa ; Ngundam, Franklyn ; Milner, Erin ; Schenk, Amanda ; Butler, Kirk ; Nugent, Dylan ; Lee, Patricia ; Roncal, Norma ; Leed, Susan ; Hosford, Eve ; Lee, Jangwoo ; Sciotti, Richard J. ; Reichard, Gregory ; Black, Chad ; Kreishman-Deitrick, Mara ; Li, Qigui ; Vesely, Brian
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2019-02, Vol.18 (1), p.38-38, Article 38
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ArticlesPeer ReviewedFull Text
Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols
Author / Creator:Milner, Erin ; McCalmont, William ; Bhonsle, Jayendra ; Caridha, Diana ; Cobar, Jose ; Gardner, Sean ; Gerena, Lucia ; Goodine, Duane ; Lanteri, Charlotte ; Melendez, Victor ; Roncal, Norma ; Sousa, Jason ; Wipf, Peter ; Dow, Geoffrey Stuart
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2010-02, Vol.9 (1), p.51-51, Article 51
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ArticlesPeer ReviewedFull Text
Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites
Author / Creator:Li, Qigui ; Xie, Lisa ; Caridha, Diana ; Zeng, Qiang ; Zhang, Jing ; Roncal, Norma ; Zhang, Ping ; Vuong, Chau ; Potter, Brittney ; Sousa, Jason ; Marcsisin, Sean ; Read, Lisa ; Hickman, Mark
Publisher:Egypt: Hindawi Limiteds
Journal title:Malaria Research and Treatment, 2017, Vol.2017, p.1-10-008
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ArticlesPeer ReviewedFull Text
Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice
Author / Creator:Dow, Geoffrey S ; Milner, Erin ; Bathurst, Ian ; Bhonsle, Jayendra ; Caridha, Diana ; Gardner, Sean ; Gerena, Lucia ; Kozar, Michael ; Lanteri, Charlotte ; Mannila, Anne ; McCalmont, William ; Moon, Jay ; Read, Kevin D ; Norval, Suzanne ; Roncal, Norma ; Shackleford, David M ; Sousa, Jason ; Steuten, Jessica ; White, Karen L ; Zeng, Qiang ; Charman, Susan A
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2011-06, Vol.10 (1), p.150-150, Article 150
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ArticlesPeer ReviewedFull Text
Animal Models in Regulatory Breakpoint Determination: Review of New Drug Applications of Approved Antibiotics from 2014–2022
Author / Creator:Selig, Daniel ; Caridha, Diana ; Evans, Martin ; Kress, Adrian ; Lanteri, Charlotte ; Ressner, Roseanne ; DeLuca, Jesse
Publisher:Switzerland: MDPI AG
Journal title:Journal of personalized medicine, 2024-01, Vol.14 (1), p.111
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ArticlesPeer ReviewedFull Text
Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections
Author / Creator:Li, Qigui ; O’Neil, Michael ; Xie, Lisa ; Caridha, Diana ; Zeng, Qiang ; Zhang, Jing ; Pybus, Brandon ; Hickman, Mark ; Melendez, Victor
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2014-04, Vol.13 (1), p.141-141, Article 141
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ArticlesPeer ReviewedFull Text
Use of In Vivo Imaging System Technology in Leishmania major BALB/c Mouse Ear Infection Studies
Author / Creator:Cawlfield, Alicia ; Vesely, Brian ; Ngundam, Franklyn ; Butler, Kirk ; Nugent, Dylan ; Rowland, Tobin ; Caridha, Diana
Publisher:England: Entomological Society of America
Journal title:Journal of medical entomology, 2018-02, Vol.55 (2), p.429-435
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ArticlesPeer ReviewedFull Text
An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections
Author / Creator:Parker, Erica N. ; Cain, Brett N. ; Hajian, Behnoush ; Ulrich, Rebecca J. ; Geddes, Emily J. ; Barkho, Sulyman ; Lee, Hyang Yeon ; Williams, John D. ; Raynor, Malik ; Caridha, Diana ; Zaino, Angela ; Shekhar, Mrinal ; Muñoz, Kristen A. ; Rzasa, Kara M. ; Temple, Emily R. ; Hunt, Diana ; Jin, Xiannu ; Vuong, Chau ; Pannone, Kristina ; Kelly, Aya M. ; Mulligan, Michael P. ; Lee, Katie K. ; Lau, Gee W. ; Hung, Deborah T. ; Hergenrother, Paul J.
Publisher:United States: American Chemical Society
Journal title:ACS central science, 2022-08, Vol.8 (8), p.1145-1158
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ArticlesPeer ReviewedFull Text
Comparative Susceptibility of Different Mouse Strains to Liver-Stage Infection With Plasmodium berghei Sporozoites Assessed Using In Vivo Imaging
Author / Creator:Li, Qigui ; Xie, Lisa ; Caridha, Diana ; Roncal, Norma ; Zeng, Qiang ; Zhang, Jing ; Zhang, Ping ; Hickman, Mark ; Read, Lisa
Publisher:England: Oxford University Press
Journal title:Military medicine, 2017-03, Vol.182 (S1), p.360-368
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ArticlesPeer ReviewedFull Text
Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds
Author / Creator:Marcsisin, Sean R ; Sousa, Jason C ; Reichard, Gregory A ; Caridha, Diana ; Zeng, Qiang ; Roncal, Norma ; McNulty, Ronan ; Careagabarja, Julio ; Sciotti, Richard J ; Bennett, Jason W ; Zottig, Victor E ; Deye, Gregory ; Li, Qigui ; Read, Lisa ; Hickman, Mark ; Nanayakkara, N P Dhammika ; Walker, Larry A ; Smith, Bryan ; Melendez, Victor ; Pybus, Brandon S
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2014-01, Vol.13 (1), p.2-2, Article 2
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ArticlesPeer ReviewedFull Text
Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei
Author / Creator:Milner, Erin E. ; Berman, Jonathan ; Caridha, Diana ; Dickson, Samuel P. ; Hickman, Mark ; Lee, Patricia J. ; Marcsisin, Sean R. ; Read, Lisa T. ; Roncal, Norma ; Vesely, Brian A. ; Xie, Lisa H. ; Zhang, Jing ; Zhang, Ping ; Li, Qigui
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2016-12, Vol.15 (1), p.588-588, Article 588
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Correction to “An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections”
Author / Creator:Parker, Erica N. ; Cain, Brett N. ; Hajian, Behnoush ; Ulrich, Rebecca J. ; Geddes, Emily J. ; Barkho, Sulyman ; Lee, Hyang Yeon ; Williams, John D. ; Raynor, Malik ; Caridha, Diana ; Zaino, Angela ; Rohde, Jason M. ; Zak, Mark ; Shekhar, Mrinal ; Muñoz, Kristen A. ; Rzasa, Kara M. ; Temple, Emily R. ; Hunt, Diana ; Jin, Xiannu ; Vuong, Chau ; Pannone, Kristina ; Kelly, Aya M. ; Mulligan, Michael P. ; Lee, Katie K. ; Lau, Gee W. ; Hung, Deborah T. ; Hergenrother, Paul J.
Publisher:American Chemical Society
Journal title:ACS central science, 2022-09, Vol.8 (9), p.1362-1362
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ArticlesPeer ReviewedFull Text
Direct Comparison of the Efficacy and Safety of Oral Treatments with Oleylphosphocholine (OlPC) and Miltefosine in a Mouse Model of L. major Cutaneous Leishmaniasis: e3144
Author / Creator:tin, Anny ; Caridha, Diana P ; Leed, Susan ; Ngundam, Franklyn ; Sena, Jenell ; Bosschaerts, Tom ; Parriott, Sandi ; Hickman, Mark R ; Hudson, Thomas H ; Grogl, Max
Publisher:San Francisco: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2014-09, Vol.8 (9)
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ArticlesPeer ReviewedFull Text
Gene expressions in Jurkat cells poisoned by a sulphur mustard vesicant and the induction of apoptosis
Author / Creator:Zhang, Peng ; Ng, Patrick ; Caridha, Diana ; Leach, Richard A ; Asher, Ludmila V ; Novak, Mark J ; Smith, William J ; Zeichner, Steven L ; Chiang, Peter K
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:British journal of pharmacology, 2002-09, Vol.137 (2), p.245-252
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CARIDHA, DIANA awarded government contract

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The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

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Direct Comparison of the Efficacy and Safety of Oral Treatments with Oleylphosphocholine (OlPC) and Miltefosine in a Mouse Model of L. major Cutaneous Leishmaniasis

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Plerixafor for pathogen‐agnostic treatment in murine thigh infection and zebrafish sepsis

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Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

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Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

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Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

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Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice

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Animal Models in Regulatory Breakpoint Determination: Review of New Drug Applications of Approved Antibiotics from 2014–2022

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Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections

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Use of In Vivo Imaging System Technology in Leishmania major BALB/c Mouse Ear Infection Studies

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An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections

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Comparative Susceptibility of Different Mouse Strains to Liver-Stage Infection With Plasmodium berghei Sporozoites Assessed Using In Vivo Imaging

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Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

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Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei

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Correction to “An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections”

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Direct Comparison of the Efficacy and Safety of Oral Treatments with Oleylphosphocholine (OlPC) and Miltefosine in a Mouse Model of L. major Cutaneous Leishmaniasis: e3144

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Gene expressions in Jurkat cells poisoned by a sulphur mustard vesicant and the induction of apoptosis

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