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Books
Marco Polo : the incredible journey / Robin Brown ; foreword by Jeremy Catto.
Author / Creator:Brown, Robin, 1937-
Publisher:Stroud : Sutton, 2005.
Date:2005.
Call Numbers:N910.92/40
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ArticlesPeer ReviewedFull Text
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds
Author / Creator:Stefanachi, Angela ; Leonetti, Francesco ; Pisani, Leonardo ; Catto, Marco ; Carotti, Angelo
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-01, Vol.23 (2), p.250
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Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease
Author / Creator:Hafez, Donia E. ; Dubiel, Mariam ; La Spada, Gabriella ; Catto, Marco ; Reiner-Link, David ; Syu, Yu-Ting ; Abdel-Halim, Mohammad ; Hwang, Tsong-Long ; Stark, Holger ; Abadi, Ashraf H.
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2175821-2175821
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A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)
Author / Creator:Leuci, Rosalba ; Brunetti, Leonardo ; Laghezza, Antonio ; Piemontese, Luca ; Carrieri, Antonio ; Pisani, Leonardo ; Tortorella, Paolo ; Catto, Marco ; Loiodice, Fulvio
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-01, Vol.27 (3), p.958
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Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases
Author / Creator:Purgatorio, Rosa ; Gambacorta, Nicola ; Samarelli, Francesco ; Lopopolo, Gianfranco ; de Candia, Modesto ; Catto, Marco ; Nicolotti, Orazio ; Altomare, Cosimo D.
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-07, Vol.27 (13), p.4269
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First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease
Author / Creator:Purgatorio, Rosa ; Gambacorta, Nicola ; de Candia, Modesto ; Catto, Marco ; Rullo, Mariagrazia ; Pisani, Leonardo ; Nicolotti, Orazio ; Altomare, Cosimo D.
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-08, Vol.26 (17), p.5208
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Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity
Author / Creator:Paolino, Marco ; de Candia, Modesto ; Purgatorio, Rosa ; Catto, Marco ; Saletti, Mario ; Tondo, Anna Rita ; Nicolotti, Orazio ; Cappelli, Andrea ; Brizzi, Antonella ; Mugnaini, Claudia ; Corelli, Federico ; Altomare, Cosimo D.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-08, Vol.28 (15), p.5857
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Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease
Author / Creator:Piemontese, Luca ; Vitucci, Gabriele ; Catto, Marco ; Laghezza, Antonio ; Perna, Filippo Maria ; Rullo, Mariagrazia ; Loiodice, Fulvio ; Capriati, Vito ; Solfrizzo, Michele
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-08, Vol.23 (9), p.2182
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Synthesis of Novel Benzo[b][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors
Author / Creator:Kulikova, Larisa N. ; Raesi, Ghulam Reza ; Levickaya, Daria D. ; Purgatorio, Rosa ; Spada, Gabriella La ; Catto, Marco ; Altomare, Cosimo D. ; Voskressensky, Leonid G.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1662
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ArticlesPeer ReviewedFull Text
N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases
Author / Creator:Bautista-Aguilera, Óscar M. ; Alonso, José M. ; Catto, Marco ; Iriepa, Isabel ; Knez, Damijan ; Gobec, Stanislav ; Marco-Contelles, José
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-11, Vol.27 (21), p.7437
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ArticlesPeer ReviewedFull Text
First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer’s Disease
Author / Creator:Guieu, Benjamin ; Lecoutey, Cedric ; Legay, Rémi ; Davis, Audrey ; Sopkova de Oliveira Santos, Jana ; Altomare, Cosimo Damiano ; Catto, Marco ; Rochais, Christophe ; Dallemagne, Patrick
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-01, Vol.26 (1), p.80
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Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity
Author / Creator:Titov, Alexander A. ; Purgatorio, Rosa ; Obydennik, Arina Y. ; Listratova, Anna V. ; Borisova, Tatiana N. ; de Candia, Modesto ; Catto, Marco ; Altomare, Cosimo D. ; Varlamov, Alexey V. ; Voskressensky, Leonid G.
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-09, Vol.27 (19), p.6276
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ArticlesPeer ReviewedFull Text
Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer’s Disease
Author / Creator:Purgatorio, Rosa ; Gambacorta, Nicola ; Catto, Marco ; de Candia, Modesto ; Pisani, Leonardo ; Espargaró, Alba ; Sabaté, Raimon ; Cellamare, Saverio ; Nicolotti, Orazio ; Altomare, Cosimo
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-12, Vol.25 (23), p.5773
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Searching for Multi-Targeting Neurotherapeutics against Alzheimer’s: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif
Author / Creator:Pisani, Leonardo ; Farina, Roberta ; Soto-Otero, Ramon ; Denora, Nunzio ; Mangiatordi, Giuseppe ; Nicolotti, Orazio ; Mendez-Alvarez, Estefania ; Altomare, Cosimo ; Catto, Marco ; Carotti, Angelo
Publisher:Switzerland: MDPI
Journal title:Molecules (Basel, Switzerland), 2016-03, Vol.21 (3), p.362-362
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ArticlesPeer ReviewedFull Text
Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity
Author / Creator:Purgatorio, Rosa ; De Candia, Modesto ; De Palma, Annalisa ; De Santis, Francesco ; Pisani, Leonardo ; Campagna, Francesco ; Cellamare, Saverio ; Altomare, Cosimo Damiano ; Catto, Marco
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-06, Vol.23 (7), p.1544
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A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics
Author / Creator:Purgatorio, Rosa ; Boccarelli, Angelina ; Pisani, Leonardo ; de Candia, Modesto ; Catto, Marco ; Altomare, Cosimo
Publisher:Switzerland: MDPI AG
Journal title:Antioxidants, 2024-01, Vol.13 (1), p.133
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Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer’s Disease Potential
Author / Creator:Nevskaya, Alisa A. ; Anikina, Lada V. ; Purgatorio, Rosa ; Catto, Marco ; Nicolotti, Orazio ; de Candia, Modesto ; Pisani, Leonardo ; Borisova, Tatiana N. ; Miftyakhova, Almira R. ; Varlamov, Aleksey V. ; Nevskaya, Elena Yu ; Borisov, Roman S. ; Voskressensky, Leonid G. ; Altomare, Cosimo D.
Publisher:Switzerland: MDPI
Journal title:Molecules (Basel, Switzerland), 2021-01, Vol.26 (2), p.359
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ArticlesPeer ReviewedFull Text
Design, Synthesis and 5-HT1A Binding Affinity of N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)tricyclo[3.3.1.13,7]decan-1-amine and N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-3,5-dimethyl-tricy...
Author / Creator:Zoidis, Grigoris ; Loza, María Isabel ; Catto, Marco
Publisher:Basel: MDPI AG
Journal title:MolBank, 2022-03, Vol.2022 (1), p.M1353
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Nature-Inspired 1-Phenylpyrrolo[2,1-a]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance
Author / Creator:Nevskaya, Alisa A. ; Purgatorio, Rosa ; Borisova, Tatiana N. ; Varlamov, Alexey V. ; Anikina, Lada V. ; Obydennik, Arina Yu ; Nevskaya, Elena Yu ; Niso, Mauro ; Colabufo, Nicola A. ; Carrieri, Antonio ; Catto, Marco ; de Candia, Modesto ; Voskressensky, Leonid G. ; Altomare, Cosimo D.
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2024-04, Vol.17 (4), p.539
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ArticlesPeer ReviewedFull Text
Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease
Author / Creator:Carocci, Alessia ; Barbarossa, Alexia ; Leuci, Rosalba ; Carrieri, Antonio ; Brunetti, Leonardo ; Laghezza, Antonio ; Catto, Marco ; Limongelli, Francesco ; Chaves, Sílvia ; Tortorella, Paolo ; Altomare, Cosimo Damiano ; Santos, Maria Amélia ; Loiodice, Fulvio ; Piemontese, Luca
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2022-08, Vol.11 (9), p.1631
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Showing 1 to 20 of 34 results

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Marco Polo : the incredible journey / Robin Brown ; foreword by Jeremy Catto.

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Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds

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Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease

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A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)

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Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases

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First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease

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Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity

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Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease

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Synthesis of Novel Benzo[b][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors

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N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

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First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer’s Disease

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Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity

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Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer’s Disease

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Searching for Multi-Targeting Neurotherapeutics against Alzheimer’s: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif

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Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity

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A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics

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Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer’s Disease Potential

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Design, Synthesis and 5-HT1A Binding Affinity of N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)tricyclo[3.3.1.13,7]decan-1-amine and N-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-3,5-dimethyl-tricy...

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Nature-Inspired 1-Phenylpyrrolo[2,1-a]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance

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Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease

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