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Artificially cloaked viral nanovaccine for cancer immunotherapy
Author / Creator:Fusciello, Manlio ; Fontana, Flavia ; Tähtinen, Siri ; Capasso, Cristian ; Feola, Sara ; Martins, Beatriz ; Chiaro, Jacopo ; Peltonen, Karita ; Ylösmäki, Leena ; Ylösmäki, Erkko ; Hamdan, Firas ; Kari, Otto K. ; Ndika, Joseph ; Alenius, Harri ; Urtti, Arto ; Hirvonen, Jouni T. ; Santos, Hélder A. ; Cerullo, Vincenzo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5747-13, Article 5747
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Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102 - Support for clinical studies on advanced cancer treatment
Author / Creator:Kuryk, Lukasz ; Vassilev, Lotta ; Ranki, Tuuli ; Hemminki, Akseli ; Karioja-Kallio, Aila ; Levälampi, Onerva ; Vuolanto, Antti ; Cerullo, Vincenzo ; Pesonen, Sari
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-08, Vol.12 (8), p.e0182715
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The evolution of adenoviral vectors through genetic and chemical surface modifications
Author / Creator:Capasso, Cristian ; Garofalo, Mariangela ; Hirvinen, Mari ; Cerullo, Vincenzo
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2014-02, Vol.6 (2), p.832-855
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Development of mesothelioma-specific oncolytic immunotherapy enabled by immunopeptidomics of murine and human mesothelioma tumors
Author / Creator:Chiaro, Jacopo ; Antignani, Gabriella ; Feola, Sara ; Feodoroff, Michaela ; Martins, Beatriz ; Cojoc, Hanne ; Russo, Salvatore ; Fusciello, Manlio ; Hamdan, Firas ; Ferrari, Valentina ; Ciampi, Daniele ; Ilonen, Ilkka ; Räsänen, Jari ; Mäyränpää, Mikko ; Partanen, Jukka ; Koskela, Satu ; Honkanen, Jarno ; Halonen, Jussi ; Kuryk, Lukasz ; Rescigno, Maria ; Grönholm, Mikaela ; Branca, Rui M. ; Lehtiö, Janne ; Cerullo, Vincenzo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7056-7056, Article 7056
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An Oncolytic Adenovirus Enhanced for Toll-like Receptor 9 Stimulation Increases Antitumor Immune Responses and Tumor Clearance
Author / Creator:Cerullo, Vincenzo ; Diaconu, Iulia ; Romano, Valentina ; Hirvinen, Mari ; Ugolini, Matteo ; Escutenaire, Sophie ; Holm, Sirkka-Liisa ; Kipar, Anja ; Kanerva, Anna ; Hemminki, Akseli
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2012-11, Vol.20 (11), p.2076-2086
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A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines
Author / Creator:Feola, Sara ; Chiaro, Jacopo ; Martins, Beatriz ; Russo, Salvatore ; Fusciello, Manlio ; Ylösmäki, Erkko ; Bonini, Chiara ; Ruggiero, Eliana ; Hamdan, Firas ; Feodoroff, Michaela ; Antignani, Gabriella ; Viitala, Tapani ; Pesonen, Sari ; Grönholm, Mikaela ; Branca, Rui M M ; Lehtiö, Janne ; Cerullo, Vincenzo
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2022-03, Vol.11
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Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy
Author / Creator:Ylösmäki, Leena ; Polini, Beatrice ; Carpi, Sara ; Martins, Beatriz ; Smertina, Elena ; Feola, Sara ; Fusciello, Manlio ; Peltonen, Karita ; Nieri, Paola ; Ylösmäki, Erkko ; Cerullo, Vincenzo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-10, Vol.14 (10), p.e0224072-e0224072
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Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice
Author / Creator:Leggiero, Eleonora ; Labruna, Giuseppe ; Iaffaldano, Laura ; Lombardo, Barbara ; Greco, Adelaide ; Fiorenza, Dario ; Gramanzini, Matteo ; Montanaro, Donatella ; Baldi, Alfonso ; Cerullo, Vincenzo ; Sacchetti, Lucia ; Pastore, Lucio
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2019-04, Vol.26 (3-4), p.121-130
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Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-...
Author / Creator:Hamdan, Firas ; Ylösmäki, Erkko ; Chiaro, Jacopo ; Giannoula, Yvonne ; Long, Maeve ; Fusciello, Manlio ; Feola, Sara ; Martins, Beatriz ; Feodoroff, Michaela ; Antignani, Gabriella ; Russo, Salvatore ; Kari, Otto ; Lee, Moon Hee ; Järvinen, Petrus ; Nisen, Harry ; Kreutzman, Anna ; Leusen, Jeanette ; Mustjoki, Satu ; McWilliams, Thomas G ; Grönholm, Mikaela ; Cerullo, Vincenzo
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e003000
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Novel personalized cancer vaccine platform based on Bacillus Calmette-Guèrin
Author / Creator:Ylösmäki, Erkko ; Fusciello, Manlio ; Martins, Beatriz ; Feola, Sara ; Hamdan, Firas ; Chiaro, Jacopo ; Ylösmäki, Leena ; Vaughan, Matthew J ; Viitala, Tapani ; Kulkarni, Prasad S ; Cerullo, Vincenzo
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-07, Vol.9 (7), p.e002707
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Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors
Author / Creator:Feola, Sara ; Hamdan, Firas ; Russo, Salvatore ; Chiaro, Jacopo ; Fusciello, Manlio ; Feodoroff, Michaela ; Antignani, Gabriella ; D'Alessio, Federica ; Mölsä, Riikka ; Stigzelius, Virpi ; Bottega, Paolo ; Pesonen, Sari ; Leusen, Jeanette ; Grönholm, Mikaela ; Cerullo, Vincenzo
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2024-03, Vol.12 (3), p.e008342
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Transdermal delivery of PeptiCRAd cancer vaccine using microneedle patches
Author / Creator:D'Amico, Carmine ; Fusciello, Manlio ; Hamdan, Firas ; D'Alessio, Federica ; Bottega, Paolo ; Saklauskaite, Milda ; Russo, Salvatore ; Cerioni, Justin ; Elbadri, Khalil ; Kemell, Marianna ; Hirvonen, Jouni ; Cerullo, Vincenzo ; Santos, Hélder A.
Publisher:China: Elsevier B.V
Journal title:Bioactive materials, 2025-03, Vol.45, p.115-127
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Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site
Author / Creator:Lopes, Alessandra ; Feola, Sara ; Ligot, Sophie ; Fusciello, Manlio ; Vandermeulen, Gaëlle ; Préat, Véronique ; Cerullo, Vincenzo
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2019-07, Vol.7 (1), p.174-174, Article 174
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Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus
Author / Creator:Ahtiainen, Laura ; Mirantes, Cristina ; Jahkola, Tiina ; Escutenaire, Sophie ; Diaconu, Iulia ; Osterlund, Pamela ; Kanerva, Anna ; Cerullo, Vincenzo ; Hemminki, Akseli
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-11, Vol.5 (11), p.e13859-e13859
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Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles
Author / Creator:Lázaro-Ibáñez, Elisa ; Neuvonen, Maarit ; Takatalo, Maarit ; Thanigai Arasu, Uma ; Capasso, Cristian ; Cerullo, Vincenzo ; Rhim, Johng S. ; Rilla, Kirsi ; Yliperttula, Marjo ; Siljander, Pia R.-M.
Publisher:Sweden: Taylor & Francis
Journal title:Journal of extracellular vesicles, 2017-12, Vol.6 (1), p.1354645-n/a
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Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity
Author / Creator:Hirvinen, Mari ; Capasso, Cristian ; Guse, Kilian ; Garofalo, Mariangela ; Vitale, Andrea ; Ahonen, Marko ; Kuryk, Lukasz ; Vähä-Koskela, Markus ; Hemminki, Akseli ; Fortino, Vittorio ; Greco, Dario ; Cerullo, Vincenzo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Oncolytics, 2016, Vol.3 (C), p.16002-16002, Article 16002
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Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes
Author / Creator:Ruan, Merry Zc ; Cerullo, Vincenzo ; Cela, Racel ; Clarke, Chris ; Lundgren-Akerlund, Evy ; Barry, Michael A ; Lee, Brendan Hl
Publisher:United States: Elsevier Limited
Journal title:Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16008-16008, Article 16008
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Beyond Gene Delivery: Strategies to Engineer the Surfaces of Viral Vectors
Author / Creator:Capasso, Cristian ; Hirvinen, Mari ; Cerullo, Vincenzo
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2013-12, Vol.1 (1), p.3-16
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ArticlesPeer ReviewedFull Text
Combinatorial treatment with oncolytic adenovirus and helper-dependent adenovirus augments adenoviral cancer gene therapy
Author / Creator:Farzad, Lisa ; Cerullo, Vincenzo ; Yagyu, Shigeki ; Bertin, Terry ; Hemminki, Akseli ; Rooney, Cliona ; Lee, Brendan ; Suzuki, Masataka
Publisher:Milwaukee: Elsevier Limited
Journal title:Molecular therapy. Oncolytics, 2014-01, Vol.1, p.14008
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Calcium gluconate in phosphate buffered saline increases gene delivery with adenovirus type 5
Author / Creator:Ahonen, Marko T ; Diaconu, Iulia ; Pesonen, Sari ; Kanerva, Anna ; Baumann, Marc ; Parviainen, Suvi T ; Spiller, Brad ; Cerullo, Vincenzo ; Hemminki, Akseli
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-09, Vol.5 (9), p.e13103
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Showing 1 to 20 of 74 results

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Artificially cloaked viral nanovaccine for cancer immunotherapy

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Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102 - Support for clinical studies on advanced cancer treatment

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The evolution of adenoviral vectors through genetic and chemical surface modifications

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Development of mesothelioma-specific oncolytic immunotherapy enabled by immunopeptidomics of murine and human mesothelioma tumors

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An Oncolytic Adenovirus Enhanced for Toll-like Receptor 9 Stimulation Increases Antitumor Immune Responses and Tumor Clearance

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A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines

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Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy

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Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

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Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-...

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Novel personalized cancer vaccine platform based on Bacillus Calmette-Guèrin

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Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors

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Transdermal delivery of PeptiCRAd cancer vaccine using microneedle patches

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Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site

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Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus

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Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles

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Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

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Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes

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Beyond Gene Delivery: Strategies to Engineer the Surfaces of Viral Vectors

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Combinatorial treatment with oncolytic adenovirus and helper-dependent adenovirus augments adenoviral cancer gene therapy

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Calcium gluconate in phosphate buffered saline increases gene delivery with adenovirus type 5

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