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ArticlesPeer ReviewedFull Text
Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial
Author / Creator:Hodi, Frank Stephen, MD ; Chiarion-Sileni, Vanna, MD ; Gonzalez, Rene, Prof ; Grob, Jean-Jacques, Prof ; Rutkowski, Piotr, Prof ; Cowey, Charles Lance, MD ; Lao, Christopher D, MD ; Schadendorf, Dirk, Prof ; Wagstaff, John, Prof ; Dummer, Reinhard, MD ; Ferrucci, Pier Francesco, MD ; Smylie, Michael, MD ; Hill, Andrew, MD ; Hogg, David, MD ; Marquez-Rodas, Ivan, Prof ; Jiang, Joel, PhD ; Rizzo, Jasmine, MD ; Larkin, James, FRCP ; Wolchok, Jedd D, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-11, Vol.19 (11), p.1480-1492
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ArticlesPeer ReviewedFull Text
Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial
Author / Creator:Eggermont, Alexander M M, Prof ; Chiarion-Sileni, Vanna, MD ; Grob, Jean-Jacques, Prof ; Dummer, Reinhard, Prof ; Wolchok, Jedd D, MD ; Schmidt, Henrik, MD ; Hamid, Omid, MD ; Robert, Caroline, Prof ; Ascierto, Paolo A, Prof ; Richards, Jon M, MD ; Lebbé, Céleste, Prof ; Ferraresi, Virginia, MD ; Smylie, Michael, MD ; Weber, Jeffrey S, MD ; Maio, Michele, MD ; Konto, Cyril, MD ; Hoos, Axel, MD ; de Pril, Veerle, MSc ; Gurunath, Ravichandra Karra, MD ; de Schaetzen, Gaetan, PhD ; Suciu, Stefan, PhD ; Testori, Alessandro, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-05, Vol.16 (5), p.522-530
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ArticlesPeer ReviewedFull Text
Dabrafenib in BRAF -mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
Author / Creator:Hauschild, Axel, Prof ; Grob, Jean-Jacques, Prof ; Demidov, Lev V, Prof ; Jouary, Thomas, MD ; Gutzmer, Ralf, MD ; Millward, Michael, MD ; Rutkowski, Piotr, PhD ; Blank, Christian U, PhD ; Miller, Wilson H, PhD ; Kaempgen, Eckhart, PhD ; Martín-Algarra, Salvador, PhD ; Karaszewska, Boguslawa, MD ; Mauch, Cornelia, Prof ; Chiarion-Sileni, Vanna, MD ; Martin, Anne-Marie, PhD ; Swann, Suzanne, PhD ; Haney, Patricia, BSN ; Mirakhur, Beloo, PhD ; Guckert, Mary E, MSN ; Goodman, Vicki, MD ; Chapman, Paul B, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2012-07, Vol.380 (9839), p.358-365
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ArticlesPeer ReviewedFull Text
Comparison of dabrafenib and trametinib combination therapy with vemurafenib monotherapy on health-related quality of life in patients with unresectable or metastatic cutaneous BRAF Val600-mutation-po...
Author / Creator:Grob, Jean Jacques, Prof ; Amonkar, Mayur M, PhD ; Karaszewska, Boguslawa, MD ; Schachter, Jacob, Prof ; Dummer, Reinhard, Prof ; Mackiewicz, Andrzej, Prof ; Stroyakovskiy, Daniil, MD ; Drucis, Kamil, MD ; Grange, Florent, MD ; Chiarion-Sileni, Vanna, MD ; Rutkowski, Piotr, Prof ; Lichinitser, Mikhail, Prof ; Levchenko, Evgeny, MD ; Wolter, Pascal, MD ; Hauschild, Axel, Prof ; Long, Georgina V, MD ; Nathan, Paul, MD ; Ribas, Antoni, Prof ; Flaherty, Keith, MD ; Sun, Peng, PhD ; Legos, Jeffrey J, PhD ; McDowell, Diane Opatt, MD ; Mookerjee, Bijoyesh, MD ; Schadendorf, Dirk, Prof ; Robert, Caroline, MD
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2015-10, Vol.16 (13), p.1389-1398
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ArticlesPeer ReviewedFull Text
Health-related quality of life with adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): secondary outcomes of a multinational, randomised, double...
Author / Creator:Coens, Corneel, MSc ; Suciu, Stefan, PhD ; Chiarion-Sileni, Vanna, MD ; Grob, Jean-Jacques, Prof ; Dummer, Reinhard, Prof ; Wolchok, Jedd D, MD ; Schmidt, Henrik, MD ; Hamid, Omid, MD ; Robert, Caroline, Prof ; Ascierto, Paolo A, Prof ; Richards, Jon M, MD ; Lebbé, Celeste, Prof ; Ferraresi, Virginia, MD ; Smylie, Michael, MD ; Weber, Jeffrey S, MD ; Maio, Michele, MD ; Bottomley, Andrew, PhD ; Kotapati, Srividya, PharmD ; de Pril, Veerle ; Testori, Alessandro, MD ; Eggermont, Alexander M M, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-03, Vol.18 (3), p.393-403
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ArticlesPeer ReviewedFull Text
Atezolizumab, vemurafenib, and cobimetinib in patients with melanoma with CNS metastases (TRICOTEL): a multicentre, open-label, single-arm, phase 2 study
Author / Creator:Dummer, Reinhard, Prof ; Queirolo, Paola, MD ; Gerard Duhard, Pauline, PharmD ; Hu, Youyou, PhD ; Wang, Dao, PhD ; de Azevedo, Sergio Jobim, MD ; Robert, Caroline, Prof ; Ascierto, Paolo Antonio, Prof ; Chiarion-Sileni, Vanna, MD ; Pronzato, Paolo, MD ; Spagnolo, Francesco, MD ; Mujika Eizmendi, Karmele, MD ; Liszkay, Gabriella, Prof ; de la Cruz Merino, Luis, MD ; Tawbi, Hussein, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2023-12, Vol.24 (12), p.e461-e471
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ArticlesPeer ReviewedFull Text
RETRACTED: Atezolizumab, vemurafenib, and cobimetinib in patients with melanoma with CNS metastases (TRICOTEL): a multicentre, open-label, single-arm, phase 2 study
Author / Creator:Dummer, Reinhard, Prof ; Queirolo, Paola, MD ; Abajo Guijarro, Ana Maria, PhD ; Hu, Youyou, PhD ; Wang, Dao, PhD ; de Azevedo, Sergio Jobim, MD ; Robert, Caroline, Prof ; Ascierto, Paolo Antonio, Prof ; Chiarion-Sileni, Vanna, MD ; Pronzato, Paolo, MD ; Spagnolo, Francesco, MD ; Mujika Eizmendi, Karmele, MD ; Liszkay, Gabriella, Prof ; de la Cruz Merino, Luis, MD ; Tawbi, Hussein, Prof
Publisher:Elsevier Ltd
Journal title:The lancet oncology, 2022-09, Vol.23 (9), p.1145-1155
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ArticlesPeer ReviewedFull Text
Adjuvant dabrafenib plus trametinib versus placebo in patients with resected, BRAFV600-mutant, stage III melanoma (COMBI-AD): exploratory biomarker analyses from a randomised, phase 3 trial
Author / Creator:Dummer, Reinhard, Prof ; Brase, Jan C, PhD ; Garrett, James, PhD ; Campbell, Catarina D, PhD ; Gasal, Eduard, MD ; Squires, Matthew, PhD ; Gusenleitner, Daniel, PhD ; Santinami, Mario, MD ; Atkinson, Victoria, MD ; Mandalà, Mario, MD ; Chiarion-Sileni, Vanna, MD ; Flaherty, Keith, MD ; Larkin, James, Prof ; Robert, Caroline, Prof ; Kefford, Richard, Prof ; Kirkwood, John M, Prof ; Hauschild, Axel, Prof ; Schadendorf, Dirk, Prof ; Long, Georgina V, Prof
Publisher:Elsevier Ltd
Journal title:The lancet oncology, 2020-03, Vol.21 (3), p.358-372
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ArticlesPeer ReviewedFull Text
Dabrafenib plus trametinib in patients with BRAFV600 -mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial
Author / Creator:Davies, Michael A, Dr ; Saiag, Philippe, Prof ; Robert, Caroline, Prof ; Grob, Jean-Jacques, Prof ; Flaherty, Keith T, Prof ; Arance, Ana, MD ; Chiarion-Sileni, Vanna, MD ; Thomas, Luc, Prof ; Lesimple, Thierry, MD ; Mortier, Laurent, Prof ; Moschos, Stergios J, MD ; Hogg, David, MD ; Márquez-Rodas, Iván, Prof ; Del Vecchio, Michele, Prof ; Lebbé, Céleste, Prof ; Meyer, Nicolas, Prof ; Zhang, Ying, PhD ; Huang, Yingjie, MD ; Mookerjee, Bijoyesh, MD ; Long, Georgina V, Prof
Publisher:London: Elsevier Ltd
Journal title:The lancet oncology, 2017-07, Vol.18 (7), p.863-873
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ArticlesPeer ReviewedFull Text
Vemurafenib in patients with BRAFV600 mutated metastatic melanoma: an open-label, multicentre, safety study
Author / Creator:Larkin, James, Dr ; Del Vecchio, Michele, MD ; Ascierto, Paolo A, MD ; Krajsova, Ivana, MD ; Schachter, Jacob, Prof ; Neyns, Bart, MD ; Espinosa, Enrique, MD ; Garbe, Claus, Prof ; Sileni, Vanna Chiarion, MD ; Gogas, Helen, MD ; Miller, Wilson H, MD ; Mandalà, Mario, MD ; Hospers, Geke A P, Prof ; Arance, Ana, MD ; Queirolo, Paola, Prof ; Hauschild, Axel, Prof ; Brown, Michael P, PhD ; Mitchell, Lada, PhD ; Veronese, Luisa, MD ; Blank, Christian U, Dr
Publisher:Elsevier Ltd
Journal title:The lancet oncology, 2014-04, Vol.15 (4), p.436-444
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Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial

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Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial

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Dabrafenib in BRAF -mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

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Comparison of dabrafenib and trametinib combination therapy with vemurafenib monotherapy on health-related quality of life in patients with unresectable or metastatic cutaneous BRAF Val600-mutation-po...

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Health-related quality of life with adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): secondary outcomes of a multinational, randomised, double...

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Atezolizumab, vemurafenib, and cobimetinib in patients with melanoma with CNS metastases (TRICOTEL): a multicentre, open-label, single-arm, phase 2 study

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RETRACTED: Atezolizumab, vemurafenib, and cobimetinib in patients with melanoma with CNS metastases (TRICOTEL): a multicentre, open-label, single-arm, phase 2 study

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Adjuvant dabrafenib plus trametinib versus placebo in patients with resected, BRAFV600-mutant, stage III melanoma (COMBI-AD): exploratory biomarker analyses from a randomised, phase 3 trial

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Dabrafenib plus trametinib in patients with BRAFV600 -mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial

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Vemurafenib in patients with BRAFV600 mutated metastatic melanoma: an open-label, multicentre, safety study

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