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ArticlesPeer ReviewedFull Text
Autophagy as a modulator of cell death machinery
Author / Creator:Noguchi Masayuki ; Hirata Noriyuki ; Tanaka, Tsutomu ; Suizu Futoshi ; Nakajima, Hiroshi ; Chiorini, John A
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2020-07, Vol.11 (7)
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Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren’s disease
Author / Creator:Nakamura, Hiroyuki ; Tanaka, Tsutomu ; Ji, Youngmi ; Zheng, Changyu ; Afione, Sandra A. ; Warner, Blake M. ; Oliveira, Fabiola Reis ; Motta, Ana Carolina F. ; Rocha, Eduardo M. ; Noguchi, Masayuki ; Atsumi, Tatsuya ; Chiorini, John A.
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLOS ONE, 2023-02, Vol.18 (2), p.e0282227
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Aquaporin gene therapy corrects Sjögren’s syndrome phenotype in mice
Author / Creator:Lai, Zhennan ; Yin, Hongen ; Cabrera-Pérez, Javier ; Guimaro, Maria C. ; Afione, Sandra ; Michael, Drew G. ; Glenton, Patricia ; Patel, Ankur ; Swaim, William D. ; Zheng, Changyu ; Nguyen, Cuong Q. ; Nyberg, Fred ; Chiorini, John A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (20), p.5694-5699
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ArticlesPeer ReviewedFull Text
Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy
Author / Creator:Nakamura, Hiroyuki ; Tanaka, Tsutomu ; Zheng, Changyu ; Afione, Sandra A. ; Warner, Blake M. ; Noguchi, Masayuki ; Atsumi, Tatsuya ; Chiorini, John A.
Publisher:London: Springer Science and Business Media LLC
Journal title:Scientific Reports, 2022-11, Vol.12 (1), p.18570-13, Article 18570
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Lysosome-associated membrane protein 3 misexpression in salivary glands induces a Sjögren’s syndrome-like phenotype in mice
Author / Creator:Nakamura, Hiroyuki ; Tanaka, Tsutomu ; Pranzatelli, Thomas ; Ji, Youngmi ; Yin, Hongen ; Perez, Paola ; Afione, Sandra A ; Jang, Shyh-Ing ; Goldsmith, Corrine ; Zheng, Chang Yu ; Swaim, William D ; Warner, Blake M ; Hirata, Noriyuki ; Noguchi, Masayuki ; Atsumi, Tatsuya ; Chiorini, John A
Publisher:United States: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2021-08, Vol.80 (8), p.1031-1039
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LAMP3 induces apoptosis and autoantigen release in Sjögren’s syndrome patients
Author / Creator:Tanaka, Tsutomu ; Warner, Blake M. ; Odani, Toshio ; Ji, Youngmi ; Mo, Ying-Qian ; Nakamura, Hiroyuki ; Jang, Shyh-Ing ; Yin, Hongen ; Michael, Drew G. ; Hirata, Noriyuki ; Suizu, Futoshi ; Ishigaki, Satoko ; Oliveira, Fabiola Reis ; Motta, Ana Carolina F. ; Ribeiro-Silva, Alfredo ; Rocha, Eduardo M. ; Atsumi, Tatsuya ; Noguchi, Masayuki ; Chiorini, John A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.15169, Article 15169
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ArticlesPeer ReviewedFull Text
Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjögren’s syndrome
Author / Creator:Mo, Ying-Qian ; Nakamura, Hiroyuki ; Tanaka, Tsutomu ; Odani, Toshio ; Perez, Paola ; Ji, Youngmi ; French, Benjamin N ; Pranzatelli, Thomas Jf ; Michael, Drew G ; Yin, Hongen ; Chow, Susan S ; Khalaj, Maryam ; Afione, Sandra A ; Zheng, Changyu ; Oliveira, Fabiola Reis ; Motta, Ana Carolina F ; Ribeiro-Silva, Alfredo ; Rocha, Eduardo M ; Nguyen, Cuong Q ; Noguchi, Masayuki ; Atsumi, Tatsuya ; Warner, Blake M ; Chiorini, John A
Publisher:United States: American Society for Clinical Investigation
Journal title:Journal of Clinical Investigation, 2022-03, Vol.132 (6)
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ArticlesPeer ReviewedFull Text
LAMP3 transfer via extracellular particles induces apoptosis in Sjögren’s disease
Author / Creator:Tanaka, Tsutomu ; Nakamura, Hiroyuki ; Tran, Duy T. ; Warner, Blake M. ; Wang, Yan ; Atsumi, Tatsuya ; Noguchi, Masayuki ; Chiorini, John A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-02, Vol.13 (1), p.2595-15, Article 2595
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ArticlesPeer ReviewedFull Text
ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference
Author / Creator:Pranzatelli, Thomas J. F. ; Michael, Drew G. ; Chiorini, John A.
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2018-07, Vol.19 (1), p.563-13, Article 563
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ArticlesPeer ReviewedFull Text
Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction
Author / Creator:Baum, Bruce J ; Alevizos, Ilias ; Zheng, Changyu ; Cotrim, Ana P ; Liu, Shuying ; McCullagh, Linda ; Goldsmith, Corinne M ; Burbelo, Peter D ; Citrin, Deborah E ; Mitchell, James B ; Nottingham, Liesl K ; Rudy, Susan F ; Van Waes, Carter ; Whatley, Millie A ; Brahim, Jaime S ; Chiorini, John A ; Danielides, Stamatina ; Turner, R. James ; Patronas, Nicholas J ; Chen, Clara C ; Nikolov, Nikolay P ; Illei, Gabor G
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19403-19407
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ArticlesPeer ReviewedFull Text
Btbd7 Regulates Epithelial Cell Dynamics and Branching Morphogenesis
Author / Creator:Onodera, Tomohiro ; Sakai, Takayoshi ; Hsu, Jeff Chi-feng ; Matsumoto, Kazue ; Chiorini, John A ; Yamada, Kenneth M
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-07, Vol.329 (5991), p.562-565
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ArticlesPeer ReviewedFull Text
Inhibition of bone morphogenetic protein 6 receptors ameliorates Sjögren’s syndrome in mice
Author / Creator:Yin, Hongen ; Kalra, Lovika ; Lai, Zhennan ; Guimaro, Maria C. ; Aber, Lauren ; Warner, Blake M. ; Michael, Drew ; Zhang, Nan ; Cabrera-Perez, Javier ; Karim, Arif ; Swaim, William D. ; Afione, Sandra ; Voigt, Alexandria ; Nguyen, Cuong Q. ; Yu, Paul B. ; Bloch, Donald B. ; Chiorini, John A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-02, Vol.10 (1), p.2967, Article 2967
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ArticlesPeer ReviewedFull Text
In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors
Author / Creator:Crispino, Giulia ; Galindo Ramirez, Fabian ; Campioni, Matteo ; Zorzi, Veronica ; Praetorius, Mark ; Di Pasquale, Giovanni ; Chiorini, John A. ; Mammano, Fabio
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.6567-13, Article 6567
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BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice
Author / Creator:Crispino, Giulia ; Di Pasquale, Giovanni ; Scimemi, Pietro ; Rodriguez, Laura ; Galindo Ramirez, Fabian ; De Siati, Romolo Daniele ; Santarelli, Rosa Maria ; Arslan, Edoardo ; Bortolozzi, Mario ; Chiorini, John A. ; Mammano, Fabio
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e23279
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Pathogenic effect of interleukin-17A in induction of Sjögren's syndrome-like disease using adenovirus-mediated gene transfer
Author / Creator:Nguyen, Cuong Q ; Yin, Hongen ; Lee, Byung Ha ; Carcamo, Wendy C ; Chiorini, John A ; Peck, Ammon B
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2010-12, Vol.12 (6), p.R220-R220, Article R220
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IL17: potential therapeutic target in Sjögren's syndrome using adenovirus-mediated gene transfer
Author / Creator:Nguyen, Cuong Q ; Yin, Hongen ; Lee, Byung Ha ; Chiorini, John A ; Peck, Ammon B
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2011-01, Vol.91 (1), p.54-62
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Correction to: ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference
Author / Creator:Pranzatelli, Thomas J. F. ; Michae, Drew G. ; Chiorini, John A.
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2019-01, Vol.20 (1), p.44-1, Article 44
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Coordinated control of connexin 26 and connexin 30 at the regulatory and functional level in the inner ear
Author / Creator:Ortolano, Saida ; Di Pasquale, Giovanni ; Crispino, Giulia ; Anselmi, Fabio ; Mammano, Fabio ; Chiorini, John A
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (48), p.18776-18781
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Identification of PDGFR as a receptor for AAV-5 transduction
Author / Creator:Pasquale, Giovanni Di ; Davidson, Beverly L ; Stein, Colleen S ; Martins, Inês ; Scudiero, Dominic ; Monks, Anne ; Chiorini, John A
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2003-10, Vol.9 (10), p.1306-1312
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Clinical and laboratory evaluation of sicca complaints: distinctive aspects of primary, secondary and non-Sjogren syndrome
Author / Creator:de Oliveira, Fabíola Reis ; Motta, Ana Carolina F. ; Módulo, Carolina Maria ; Garcia, Denny Marcos ; Chiorini, John A. ; Louzada-Junior, Paulo ; Rocha, Eduardo Melani
Publisher:BMC
Journal title:Advances in rheumatology (London, England), 2022-07, Vol.62 (1), p.23-13, Article 23
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Showing 1 to 20 of 76 results

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Autophagy as a modulator of cell death machinery

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Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren’s disease

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Aquaporin gene therapy corrects Sjögren’s syndrome phenotype in mice

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Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy

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Lysosome-associated membrane protein 3 misexpression in salivary glands induces a Sjögren’s syndrome-like phenotype in mice

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LAMP3 induces apoptosis and autoantigen release in Sjögren’s syndrome patients

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Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjögren’s syndrome

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LAMP3 transfer via extracellular particles induces apoptosis in Sjögren’s disease

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ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference

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Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

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Btbd7 Regulates Epithelial Cell Dynamics and Branching Morphogenesis

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Inhibition of bone morphogenetic protein 6 receptors ameliorates Sjögren’s syndrome in mice

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In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors

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BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice

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Pathogenic effect of interleukin-17A in induction of Sjögren's syndrome-like disease using adenovirus-mediated gene transfer

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IL17: potential therapeutic target in Sjögren's syndrome using adenovirus-mediated gene transfer

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Correction to: ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference

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Coordinated control of connexin 26 and connexin 30 at the regulatory and functional level in the inner ear

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Identification of PDGFR as a receptor for AAV-5 transduction

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Clinical and laboratory evaluation of sicca complaints: distinctive aspects of primary, secondary and non-Sjogren syndrome

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