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ArticlesPeer ReviewedFull Text
Global chemical effects of the microbiome include new bile-acid conjugations
Author / Creator:Quinn, Robert A. ; Melnik, Alexey V. ; Vrbanac, Alison ; Fu, Ting ; Patras, Kathryn A. ; Christy, Mitchell P. ; Bodai, Zsolt ; Belda-Ferre, Pedro ; Tripathi, Anupriya ; Chung, Lawton K. ; Downes, Michael ; Welch, Ryan D. ; Quinn, Melissa ; Humphrey, Greg ; Panitchpakdi, Morgan ; Weldon, Kelly C. ; Aksenov, Alexander ; da Silva, Ricardo ; Avila-Pacheco, Julian ; Clish, Clary ; Bae, Sena ; Mallick, Himel ; Franzosa, Eric A. ; Lloyd-Price, Jason ; Bussell, Robert ; Thron, Taren ; Nelson, Andrew T. ; Wang, Mingxun ; Leszczynski, Eric ; Vargas, Fernando ; Gauglitz, Julia M. ; Meehan, Michael J. ; Gentry, Emily ; Arthur, Timothy D. ; Komor, Alexis C. ; Poulsen, Orit ; Boland, Brigid S. ; Chang, John T. ; Sandborn, William J. ; Lim, Meerana ; Garg, Neha ; Lumeng, Julie C. ; Xavier, Ramnik J. ; Kazmierczak, Barbara I. ; Jain, Ruchi ; Egan, Marie ; Rhee, Kyung E. ; Ferguson, David ; Raffatellu, Manuela ; Vlamakis, Hera ; Haddad, Gabriel G. ; Siegel, Dionicio ; Huttenhower, Curtis ; Mazmanian, Sarkis K. ; Evans, Ronald M. ; Nizet, Victor ; Knight, Rob ; Dorrestein, Pieter C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-03, Vol.579 (7797), p.123-129
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Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism
Author / Creator:Wahlström, Annika ; Brumbaugh, Ariel ; Sjöland, Wilhelm ; Olsson, Lisa ; Wu, Hao ; Henricsson, Marcus ; Lundqvist, Annika ; Makki, Kassem ; Hazen, Stanley L. ; Bergström, Göran ; Marschall, Hanns-Ulrich ; Fischbach, Michael A. ; Bäckhed, Fredrik
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-05, Vol.15 (1), p.4276-4276, Article 4276
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Farnesoid X receptor is essential for normal glucose homeostasis
Author / Creator:Ma, Ke ; Saha, Pradip K ; Chan, Lawrence ; Moore, David D
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2006-04, Vol.116 (4), p.1102-1109
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Dysregulation of bile acids increases the risk for preterm birth in pregnant women
Author / Creator:You, Sangmin ; Cui, Ai-Min ; Hashmi, Syed F. ; Zhang, Xinmu ; Nadolny, Christina ; Chen, Yuan ; Chen, Qiwen ; Bush, Xin ; Hurd, Zachary ; Ali, Winifer ; Qin, Gang ; Deng, Ruitang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-04, Vol.11 (1), p.2111-15, Article 2111
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Deletion of Intestinal SHP Impairs Short-term Response to Cholic Acid Challenge in Male Mice
Author / Creator:Nguyen, James T ; Riessen, Ryan ; Zhang, Tongyu ; Kieffer, Collin ; Anakk, Sayeepriyadarshini
Publisher:US: Oxford University Press
Journal title:Endocrinology (Philadelphia), 2021-08, Vol.162 (8), p.1
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The clinical and biochemical effectiveness and safety of cholic acid treatment for bile acid synthesis defects: a systematic review
Author / Creator:Polak, Yasmin ; van Dussen, Laura ; Kemper, E Marleen ; Vaz, Frédéric M ; Klouwer, Femke C C ; Engelen, Marc ; Hollak, Carla E M
Publisher:England: BioMed Central Ltd
Journal title:Orphanet journal of rare diseases, 2024-12, Vol.19 (1), p.466-16, Article 466
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Dietary raffinose ameliorates hepatic lipid accumulation induced by cholic acid via modulation of enterohepatic bile acid circulation in rats
Author / Creator:Maegawa, Kenta ; Koyama, Haruka ; Fukiya, Satoru ; Yokota, Atsushi ; Ueda, Koichiro ; Ishizuka, Satoshi
Publisher:Cambridge, UK: Cambridge University Press
Journal title:British journal of nutrition, 2022-06, Vol.127 (11), p.1621-1630
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Loss of Hepatic Small Heterodimer Partner Elevates Ileal Bile Acids and Alters Cell Cycle-related Genes in Male Mice
Author / Creator:Shaw, Ryan Philip Henry ; Kolyvas, Peter ; Dang, Nathanlown ; Hyon, Angela ; Bailey, Keith ; Anakk, Sayeepriyadarshini
Publisher:US: Oxford University Press
Journal title:Endocrinology (Philadelphia), 2022-06, Vol.163 (6), p.1
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Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid
Author / Creator:Vico-Oton, Eduard ; Volet, Colin ; Jacquemin, Nicolas ; Dong, Yuan ; Hapfelmeier, Siegfried ; Meibom, Karin Lederballe ; Bernier-Latmani, Rizlan
Publisher:England: BioMed Central Ltd
Journal title:BMC microbiology, 2024-08, Vol.24 (1), p.286-20, Article 286
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ArticlesPeer ReviewedFull Text
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis
Author / Creator:Theofilopoulos, Spyridon ; Wang, Yuqin ; Kitambi, Satish Srinivas ; Sacchetti, Paola ; Sousa, Kyle M ; Bodin, Karl ; Kirk, Jayne ; Saltó, Carmen ; Gustafsson, Magnus ; Toledo, Enrique M ; Karu, Kersti ; Gustafsson, Jan-Åke ; Steffensen, Knut R ; Ernfors, Patrik ; Sjövall, Jan ; Griffiths, William J ; Arenas, Ernest
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2013-02, Vol.9 (2), p.126-133
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ArticlesPeer ReviewedFull Text
A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis
Author / Creator:Sakuma, Takafumi ; Nakamura, Masato ; Chiba, Tetsuhiro ; Iwanaga, Terunao ; Kan, Motoyasu ; Kojima, Ryuta ; Ao, Junjie ; Ma, Yaojia ; Unozawa, Hidemi ; Fujita, Naoto ; Kanayama, Kengo ; Kanzaki, Hiroaki ; Koroki, Keisuke ; Kobayashi, Kazufumi ; Nakagawa, Ryo ; Kanogawa, Naoya ; Kiyono, Soichiro ; Kondo, Takayuki ; Saito, Tomoko ; Ogasawara, Sadahisa ; Nakamoto, Shingo ; Muroyama, Ryosuke ; Kato, Jun ; Kishimoto, Takashi ; Kato, Naoya
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2022-10, Vol.102 (10), p.1150-1157
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ArticlesPeer ReviewedFull Text
Hypocholesterolaemic effect of dietary inclusion of two putative probiotic bile salt hydrolase-producing Lactobacillus plantarum strains in Sprague–Dawley rats
Author / Creator:Kumar, Rajesh ; Grover, Sunita ; Batish, Virender Kumar
Publisher:Cambridge, UK: Cambridge University Press
Journal title:British journal of nutrition, 2011-02, Vol.105 (4), p.561-573
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Crystal structure of the multidrug resistance regulator RamR complexed with bile acids
Author / Creator:Yamasaki, Suguru ; Nakashima, Ryosuke ; Sakurai, Keisuke ; Baucheron, Sylvie ; Giraud, Etienne ; Doublet, Benoît ; Cloeckaert, Axel ; Nishino, Kunihiko
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-01, Vol.9 (1), p.177-177, Article 177
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Hepatic Vps33b deficiency aggravates cholic acid-induced cholestatic liver injury in male mice
Author / Creator:Fu, Kai-li ; Chen, Pan ; Zhou, Yan-ying ; Jiang, Yi-ming ; Gao, Yue ; Zhang, Hui-zhen ; Guan, Li-huan ; Wang, Cong-hui ; Liu, Jun-ling ; Huang, Min ; Bi, Hui-chang
Publisher:Singapore: Springer Singapore
Journal title:Acta pharmacologica Sinica, 2022-04, Vol.43 (4), p.933-940
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ArticlesPeer ReviewedFull Text
Lactiplantibacillus plantarum PGB02 Improved Serum Cholesterol Profile by Tweaking Genes Involved in Cholesterol Homeostasis in Male Swiss Albino Mice
Author / Creator:Dhameliya, Hiren A. ; Solanki, Jyoti D. ; Patel, Dhaval T. ; George, Linz-buoy ; Thakkar, Vasudev R. ; Subramanian, R. B.
Publisher:New York: Springer US
Journal title:Applied biochemistry and biotechnology, 2023-05, Vol.195 (5), p.3180-3193
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ArticlesPeer ReviewedFull Text
Farnesoid X receptor and bile acids regulate vitamin A storage
Author / Creator:Saeed, Ali ; Yang, Jing ; Heegsma, Janette ; Groen, Albert K. ; van Mil, Saskia W. C. ; Paulusma, Coen C. ; Zhou, Lu ; Wang, Bangmao ; Faber, Klaas Nico
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-12, Vol.9 (1), p.19493-11, Article 19493
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ArticlesPeer ReviewedFull Text
The bile acid metabolome in umbilical cord blood and meconium of healthy newborns: distinct characteristics and implications
Author / Creator:Lu, Chunxia ; Gao, Zhiyong ; Zhang, Siqi ; Du, Ke ; Xu, Die ; Dong, Wenbin ; Zhang, Yujiao ; Lei, Xiaoping
Publisher:United States: PeerJ. Ltd
Journal title:PeerJ (San Francisco, CA), 2024-12, Vol.12, p.e18506, Article e18506
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Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuc...
Author / Creator:Petrov, Petar D. ; Fernández-Murga, Leonor ; Conde, Isabel ; Martínez-Sena, Teresa ; Guzmán, Carla ; Castell, José Vicente ; Jover, Ramiro
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2020-02, Vol.94 (2), p.589-607
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Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid
Author / Creator:Wu, Kang ; Liu, Yi ; Xia, Jie ; Liu, Jiale ; Wang, Kai ; Liang, Huijun ; Xu, Fengli ; Liu, Dina ; Nie, Dan ; Tang, Xin ; Huang, Ailong ; Chen, Chang ; Tang, Ni
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2024-01, Vol.11 (2), p.e2304408-n/a
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Transmembrane Polar Relay Drives the Allosteric Regulation for ABCG5/G8 Sterol Transporter
Author / Creator:Xavier, Bala M ; Zein, Aiman A ; Venes, Angelica ; Wang, Junmei ; Lee, Jyh-Yeuan
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-11, Vol.21 (22), p.8747
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Showing 1 to 20 of 89 results

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Global chemical effects of the microbiome include new bile-acid conjugations

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Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism

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Farnesoid X receptor is essential for normal glucose homeostasis

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Dysregulation of bile acids increases the risk for preterm birth in pregnant women

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Deletion of Intestinal SHP Impairs Short-term Response to Cholic Acid Challenge in Male Mice

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The clinical and biochemical effectiveness and safety of cholic acid treatment for bile acid synthesis defects: a systematic review

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Dietary raffinose ameliorates hepatic lipid accumulation induced by cholic acid via modulation of enterohepatic bile acid circulation in rats

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Loss of Hepatic Small Heterodimer Partner Elevates Ileal Bile Acids and Alters Cell Cycle-related Genes in Male Mice

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Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid

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Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

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A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis

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Hypocholesterolaemic effect of dietary inclusion of two putative probiotic bile salt hydrolase-producing Lactobacillus plantarum strains in Sprague–Dawley rats

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Crystal structure of the multidrug resistance regulator RamR complexed with bile acids

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Hepatic Vps33b deficiency aggravates cholic acid-induced cholestatic liver injury in male mice

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Lactiplantibacillus plantarum PGB02 Improved Serum Cholesterol Profile by Tweaking Genes Involved in Cholesterol Homeostasis in Male Swiss Albino Mice

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Farnesoid X receptor and bile acids regulate vitamin A storage

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The bile acid metabolome in umbilical cord blood and meconium of healthy newborns: distinct characteristics and implications

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Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuc...

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Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid

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Transmembrane Polar Relay Drives the Allosteric Regulation for ABCG5/G8 Sterol Transporter

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