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ArticlesPeer ReviewedFull Text
MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients
Author / Creator:Dwir, Daniella ; Giangreco, Basilio ; Xin, Lijing ; Tenenbaum, Liliane ; Cabungcal, Jan-Harry ; Steullet, Pascal ; Goupil, Audrey ; Cleusix, Martine ; Jenni, Raoul ; Chtarto, Abdelwahed ; Baumann, Philipp S. ; Klauser, Paul ; Conus, Philippe ; Tirouvanziam, Rabindra ; Cuenod, Michel ; Do, Kim Q.
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2020-11, Vol.25 (11), p.2889-2904
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Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia
Author / Creator:Khadimallah, Ines ; Jenni, Raoul ; Cabungcal, Jan-Harry ; Cleusix, Martine ; Fournier, Margot ; Beard, Elidie ; Klauser, Paul ; Knebel, Jean-François ; Murray, Micah M. ; Retsa, Chrysa ; Siciliano, Milena ; Spencer, Kevin M. ; Steullet, Pascal ; Cuenod, Michel ; Conus, Philippe ; Do, Kim Q.
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2022-02, Vol.27 (2), p.1192-1204
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N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis
Author / Creator:Conus, Philippe ; Seidman, Larry J ; Fournier, Margot ; Xin, Lijing ; Cleusix, Martine ; Baumann, Philipp S ; Ferrari, Carina ; Cousins, Ann ; Alameda, Luis ; Gholam-Rezaee, Mehdi ; Golay, Philippe ; Jenni, Raoul ; Woo, T -U Wilson ; Keshavan, Matcheri S ; Eap, Chin B ; Wojcik, Joanne ; Cuenod, Michel ; Buclin, Thierry ; Gruetter, Rolf ; Do, Kim Q
Publisher:United States: Oxford University Press
Journal title:Schizophrenia bulletin, 2018-03, Vol.44 (2), p.317-327
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Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psyc...
Author / Creator:Dwir, Daniella ; Cabungcal, Jan-Harry ; Xin, Lijing ; Giangreco, Basilio ; Parietti, Enea ; Cleusix, Martine ; Jenni, Raoul ; Klauser, Paul ; Conus, Philippe ; Cuénod, Michel ; Steullet, Pascal ; Do, Kim Q
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2021-11, Vol.47 (6), p.1782-1794
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Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis
Author / Creator:Pistis, Giorgio ; Vázquez-Bourgon, Javier ; Fournier, Margot ; Jenni, Raoul ; Cleusix, Martine ; Papiol, Sergi ; Smart, Sophie E. ; Pardiñas, Antonio F. ; Walters, James T. R. ; MacCabe, James H. ; Kutalik, Zoltán ; Conus, Philippe ; Crespo-Facorro, Benedicto ; Q Do, Kim
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2022-12, Vol.27 (12), p.5135-5143
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White matter microstructure alterations in early psychosis and schizophrenia
Author / Creator:Pavan, Tommaso ; Alemán-Gómez, Yasser ; Jenni, Raoul ; Steullet, Pascal ; Schilliger, Zoé ; Dwir, Daniella ; Cleusix, Martine ; Alameda, Luis ; Do, Kim Q. ; Conus, Philippe ; Hagmann, Patric ; Klauser, Paul ; Jelescu, Ileana
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2025-05, Vol.15 (1), p.179-10, Article 179
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Topology predicts long-term functional outcome in early psychosis
Author / Creator:Fournier, Margot ; Scolamiero, Martina ; Gholam-Rezaee, Mehdi M. ; Cleusix, Martine ; Jenni, Raoul ; Ferrari, Carina ; Golay, Philippe ; Baumann, Philipp S. ; Cuenod, Michel ; Conus, Philippe ; Do, Kim Q. ; Hess, Kathryn
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2021-09, Vol.26 (9), p.5335-5346
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N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial
Author / Creator:Klauser, Paul ; Xin, Lijing ; Fournier, Margot ; Griffa, Alessandra ; Cleusix, Martine ; Jenni, Raoul ; Cuenod, Michel ; Gruetter, Rolf ; Hagmann, Patric ; Conus, Philippe ; Baumann, Philipp S. ; Do, Kim Q.
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2018-10, Vol.8 (1), p.220-8, Article 220
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Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging
Author / Creator:Griffa, Alessandra ; Baumann, Philipp S. ; Klauser, Paul ; Mullier, Emeline ; Cleusix, Martine ; Jenni, Raoul ; van den Heuvel, Martijn P. ; Do, Kim Q. ; Conus, Philippe ; Hagmann, Patric
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2019-02, Vol.9 (1), p.62-62, Article 62
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M16. PROFILING GLUTAMATE AND D-SERINE PATHWAYS IN TREATMENT RESISTANT EARLY PSYCHOSIS PATIENTS
Author / Creator:Camporesi, Sara ; Khadimallah, Ines ; Fournier, Margot ; Golay, Philippe ; Xin, Lijing ; Baumann, Philipp S ; Cleusix, Martine ; Jenni, Raoul ; Ramain, Julie ; Restellini, Romeo ; Hashimoto, Kenji ; Cuenod, Michel ; Conus, Philippe ; Do, Kim Q
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2020-04, Vol.46 (Supplement_1), p.S139-S139
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Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis
Author / Creator:Alameda, Luis ; Fournier, Margot ; Khadimallah, Ines ; Griffa, Alessandra ; Cleusix, Martine ; Jenni, Raoul ; Ferrari, Carina ; Klauser, Paul ; Baumann, Philipp S. ; Cuenod, Michel ; Hagmann, Patric ; Conus, Philippe ; Do, Kim Q.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (49), p.12495-12500
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Multimodal Magnetic Resonance Imaging Depicts Widespread and Subregion Specific Anomalies in the Thalamus of Early-Psychosis and Chronic Schizophrenia Patients
Author / Creator:Alemán-Gómez, Yasser ; Baumgartner, Thomas ; Klauser, Paul ; Cleusix, Martine ; Jenni, Raoul ; Hagmann, Patric ; Conus, Philippe ; Do, Kim Q ; Bach Cuadra, Meritxell ; Baumann, Philipp S ; Steullet, Pascal
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2023-01, Vol.49 (1), p.196-207
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Characterization of early psychosis patients carrying a genetic vulnerability to redox dysregulation: a computational analysis of mechanism-based gene expression profile in fibroblasts
Author / Creator:Giangreco, Basilio ; Dwir, Daniella ; Klauser, Paul ; Jenni, Raoul ; Golay, Philippe ; Cleusix, Martine ; Baumann, Philipp S. ; Cuénod, Michel ; Conus, Philippe ; Toni, Nicolas ; Do, Kim Q.
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2023-05, Vol.28 (5), p.1983-1994
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Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis
Author / Creator:Seitz-Holland, Johanna ; Alemán-Gómez, Yasser ; Cho, Kang Ik K. ; Pasternak, Ofer ; Cleusix, Martine ; Jenni, Raoul ; Baumann, Philipp S. ; Klauser, Paul ; Conus, Philippe ; Hagmann, Patric ; Do, Kim Q. ; Kubicki, Marek ; Dwir, Daniella
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2024-06, Vol.49 (7), p.1140-1150
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N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study
Author / Creator:Mullier, Emeline ; Roine, Timo ; Griffa, Alessandra ; Xin, Lijing ; Baumann, Philipp S ; Klauser, Paul ; Cleusix, Martine ; Jenni, Raoul ; Alemàn-Gómez, Yasser ; Gruetter, Rolf ; Conus, Philippe ; Do, Kim Q ; Hagmann, Patric
Publisher:England: Oxford University Press
Journal title:The international journal of neuropsychopharmacology, 2019-08, Vol.22 (8), p.478-487
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Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex
Author / Creator:Rigucci, Silvia ; Xin, Lijing ; Klauser, Paul ; Baumann, Philipp S. ; Alameda, Luis ; Cleusix, Martine ; Jenni, Raoul ; Ferrari, Carina ; Pompili, Maurizio ; Gruetter, Rolf ; Do, Kim Q. ; Conus, Philippe
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2018-01, Vol.235 (1), p.13-22
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S164. “AT-RISK MENTAL STATES” PROGRAM IN LAUSANNE: INFLUENCE OF RECRUITMENT STRATEGIES ON THE RATE OF FALSE POSITIVES
Author / Creator:Solida, Alessandra ; Cleusix, Martine ; Zorzi, Carline ; Ferrari, Carina ; Do, Kim Q ; Conus, Philippe
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2018-04, Vol.44 (suppl_1), p.S389-S389
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S69. CLINICAL HIGH RISK STATE: STRATIFICATION BASED ON CLINICAL PROFILE AND REDOX STATUS
Author / Creator:Cleusix, Martine ; Khadimallah, Ines ; Toffel, Elodie ; Klauser, Paul ; Do, Kim Q ; von Plessen, Kerstin ; Conus, Philippe ; Solida, Alessandra
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2020-05, Vol.46 (Supplement_1), p.S60-S60
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T160. HIGH-RESOLUTION WHOLE BRAIN MR SPECTROSCOPIC IMAGING IN YOUTHS AT CLINICAL HIGH RISK FOR PSYCHOSIS: A PILOT STUDY
Author / Creator:Klauser, Paul ; Klauser, Antoine ; Cleusix, Martine ; Ledoux, Jean-Baptiste ; von Plessen, Kerstin ; Lazeyras, Francois ; Hagmann, Patric ; Conus, Philipp ; Solida, Alessandra ; Do, Kim
Publisher:US: Oxford University Press
Journal title:Schizophrenia bulletin, 2020-05, Vol.46 (Supplement_1), p.S292-S292
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Correction: MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients
Author / Creator:Dwir, Daniella ; Giangreco, Basilio ; Xin, Lijing ; Tenenbaum, Liliane ; Cabungcal, Jan-Harry ; Steullet, Pascal ; Goupil, Audrey ; Cleusix, Martine ; Jenni, Raoul ; Chtarto, Abdelwahed ; Baumann, Philipp S. ; Klauser, Paul ; Conus, Philippe ; Tirouvanziam, Rabindra ; Cuenod, Michel ; Do, Kim Q.
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2020-11, Vol.25 (11), p.3105-3105
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MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients

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Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia

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N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis

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Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psyc...

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Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis

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White matter microstructure alterations in early psychosis and schizophrenia

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Topology predicts long-term functional outcome in early psychosis

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N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial

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Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging

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M16. PROFILING GLUTAMATE AND D-SERINE PATHWAYS IN TREATMENT RESISTANT EARLY PSYCHOSIS PATIENTS

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Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis

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Multimodal Magnetic Resonance Imaging Depicts Widespread and Subregion Specific Anomalies in the Thalamus of Early-Psychosis and Chronic Schizophrenia Patients

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Characterization of early psychosis patients carrying a genetic vulnerability to redox dysregulation: a computational analysis of mechanism-based gene expression profile in fibroblasts

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Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis

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N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study

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Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex

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S164. “AT-RISK MENTAL STATES” PROGRAM IN LAUSANNE: INFLUENCE OF RECRUITMENT STRATEGIES ON THE RATE OF FALSE POSITIVES

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S69. CLINICAL HIGH RISK STATE: STRATIFICATION BASED ON CLINICAL PROFILE AND REDOX STATUS

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T160. HIGH-RESOLUTION WHOLE BRAIN MR SPECTROSCOPIC IMAGING IN YOUTHS AT CLINICAL HIGH RISK FOR PSYCHOSIS: A PILOT STUDY

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Correction: MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients

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