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ArticlesPeer ReviewedFull Text
Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection
Author / Creator:Theriot, Casey M. ; Koenigsknecht, Mark J. ; Carlson, Paul E. ; Hatton, Gabrielle E. ; Nelson, Adam M. ; Li, Bo ; Huffnagle, Gary B. ; Z. Li, Jun ; Young, Vincent B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-01, Vol.5 (1), p.3114-3114, Article 3114
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Secretion of Clostridium difficile Toxins A and B Requires the Holin-like Protein TcdE
Author / Creator:Govind, Revathi ; Dupuy, Bruno
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2012-06, Vol.8 (6), p.e1002727
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Bile acid-independent protection against Clostridioides difficile infection
Author / Creator:Aguirre, Andrea Martinez ; Yalcinkaya, Nazli ; Wu, Qinglong ; Swennes, Alton ; Tessier, Mary Elizabeth ; Roberts, Paul ; Miyajima, Fabio ; Savidge, Tor ; Sorg, Joseph A.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2021-10, Vol.17 (10), p.e1010015
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Pleiotropic roles of Clostridium difficile sin locus
Author / Creator:Girinathan, Brintha Parasumanna ; Ou, Junjun ; Dupuy, Bruno ; Govind, Revathi
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2018-03, Vol.14 (3), p.e1006940
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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
Author / Creator:Van Gorp, Hanne ; Saavedra, Pedro H. V. ; de Vasconcelos, Nathalia M. ; Van Opdenbosch, Nina ; Vande Walle, Lieselotte ; Matusiak, Magdalena ; Prencipe, Giusi ; Insalaco, Antonella ; Van Hauwermeiren, Filip ; Demon, Dieter ; Bogaert, Delfien J. ; Dullaers, Melissa ; De Baere, Elfride ; Hochepied, Tino ; Dehoorne, Joke ; Vermaelen, Karim Y. ; Haerynck, Filomeen ; De Benedetti, Fabrizio ; Lamkanfi, Mohamed
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (50), p.14384-14389
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Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
Author / Creator:Chen, Peng ; Tao, Liang ; Wang, Tianyu ; Zhang, Jie ; He, Aina ; Lam, Kwok-ho ; Liu, Zheng ; He, Xi ; Perry, Kay ; Dong, Min ; Jin, Rongsheng
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-05, Vol.360 (6389), p.664-669
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Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection
Author / Creator:Francis, Michael B. ; Allen, Charlotte A. ; Shrestha, Ritu ; Sorg, Joseph A.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2013-05, Vol.9 (5), p.e1003356
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Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection
Author / Creator:Zackular, Joseph P ; Moore, Jessica L ; Jordan, Ashley T ; Juttukonda, Lillian J ; Noto, Michael J ; Nicholson, Maribeth R ; Crews, Jonathan D ; Semler, Matthew W ; Zhang, Yaofang ; Ware, Lorraine B ; Washington, M Kay ; Chazin, Walter J ; Caprioli, Richard M ; Skaar, Eric P
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2016-11, Vol.22 (11), p.1330-1334
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Clostridioides difficile ferrosome organelles combat nutritional immunity
Author / Creator:Pi, Hualiang ; Sun, Rong ; McBride, James R. ; Kruse, Angela R. S. ; Gibson-Corley, Katherine N. ; Krystofiak, Evan S. ; Nicholson, Maribeth R. ; Spraggins, Jeffrey M. ; Zhou, Qiangjun ; Skaar, Eric P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-11, Vol.623 (7989), p.1009-1016
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C. difficile exploits a host metabolite produced during toxin-mediated disease
Author / Creator:Pruss, Kali M. ; Sonnenburg, Justin L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-05, Vol.593 (7858), p.261-265
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Host immunity modulates the efficacy of microbiota transplantation for treatment of Clostridioides difficile infection
Author / Creator:Littmann, Eric R. ; Lee, Jung-Jin ; Denny, Joshua E. ; Alam, Zahidul ; Maslanka, Jeffrey R. ; Zarin, Isma ; Matsuda, Rina ; Carter, Rebecca A. ; Susac, Bože ; Saffern, Miriam S. ; Fett, Bryton ; Mattei, Lisa M. ; Bittinger, Kyle ; Abt, Michael C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.755-15, Article 755
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ArticlesPeer ReviewedFull Text
Food for thought—The link between Clostridioides difficile metabolism and pathogenesis
Author / Creator:Marshall, Andrew ; McGrath, John W. ; Graham, Robert ; McMullan, Geoff
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-01, Vol.19 (1), p.e1011034
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Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens
Author / Creator:Yuan, Yifeng ; Zallot, Rémi ; Grove, Tyler L. ; Payan, Daniel J. ; Martin-Verstraete, Isabelle ; Šepić, Sara ; Balamkundu, Seetharamsingh ; Neelakandan, Ramesh ; Gadi, Vinod K. ; Liu, Chuan-Fa ; Swairjo, Manal A. ; Dedon, Peter C. ; Almo, Steven C. ; Gerlt, John A. ; de Crécy-Lagard, Valérie
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.19126-19135
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Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism
Author / Creator:Fachi, J. L. ; Pral, L. P. ; dos Santos, J. A. C. ; Codo, A. C. ; de Oliveira, S. ; Felipe, J. S. ; Zambom, F. F. F. ; Câmara, N. O. S. ; Vieira, P. M. M. M. ; Colonna, M. ; Vinolo, M. A. R.
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2021-07, Vol.14 (4), p.828-841
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ArticlesPeer ReviewedFull Text
Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B
Author / Creator:Yuan, Pengfei ; Zhang, Hongmin ; Cai, Changzu ; Zhu, Shiyou ; Zhou, Yuexin ; Yang, Xiaozhou ; He, Ruina ; Li, Chan ; Guo, Shengjie ; Li, Shan ; Huang, Tuxiong ; Perez-Cordon, Gregorio ; Feng, Hanping ; Wei, Wensheng
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2015-02, Vol.25 (2), p.157-168
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ArticlesPeer ReviewedFull Text
NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens
Author / Creator:Keyburn, Anthony L ; Boyce, John D ; Vaz, Paola ; Bannam, Trudi L ; Ford, Mark E ; Parker, Dane ; Di Rubbo, Antonio ; Rood, Julian I ; Moore, Robert J
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2008-02, Vol.4 (2), p.e26
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Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology
Author / Creator:Pan, Zhenrui ; Zhang, Yuanyuan ; Luo, Jianhua ; Li, Danyang ; Zhou, Yao ; He, Liuqing ; Yang, Qi ; Dong, Min ; Tao, Liang
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2021-01, Vol.17 (1), p.e1009197
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Intestinal calcium and bile salts facilitate germination of Clostridium difficile spores
Author / Creator:Kochan, Travis J. ; Somers, Madeline J. ; Kaiser, Alyssa M. ; Shoshiev, Michelle S. ; Hagan, Ada K. ; Hastie, Jessica L. ; Giordano, Nicole P. ; Smith, Ashley D. ; Schubert, Alyxandria M. ; Carlson, Paul E. ; Hanna, Philip C.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2017-07, Vol.13 (7), p.e1006443
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Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection
Author / Creator:Nabukhotna, Kateryna ; Kordus, Shannon L. ; Shupe, John A. ; Cano Rodríguez, Rubén ; Smith, Anna ; Bohannon, Julia K. ; Washington, M. Kay ; Lacy, D. Borden
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-09, Vol.20 (9), p.e1012568
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Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection
Author / Creator:Brown, Jillian R.-M. ; Flemer, Burkhardt ; Joyce, Susan A. ; Zulquernain, Akbar ; Sheehan, Donal ; Shanahan, Fergus ; O’Toole, Paul W.
Publisher:England: BioMed Central Ltd
Journal title:BMC gastroenterology, 2018-08, Vol.18 (1), p.131-15, Article 131
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Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

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Secretion of Clostridium difficile Toxins A and B Requires the Holin-like Protein TcdE

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Bile acid-independent protection against Clostridioides difficile infection

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Pleiotropic roles of Clostridium difficile sin locus

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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

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Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B

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Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection

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Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection

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Clostridioides difficile ferrosome organelles combat nutritional immunity

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C. difficile exploits a host metabolite produced during toxin-mediated disease

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Host immunity modulates the efficacy of microbiota transplantation for treatment of Clostridioides difficile infection

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Food for thought—The link between Clostridioides difficile metabolism and pathogenesis

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Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens

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Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism

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Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B

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NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens

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Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology

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Intestinal calcium and bile salts facilitate germination of Clostridium difficile spores

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Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection

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Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection

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