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ArticlesPeer ReviewedFull Text
Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy
Author / Creator:Comoglio, Paolo M. ; Trusolino, Livio ; Boccaccio, Carla
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2018-06, Vol.18 (6), p.341-358
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Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-l...
Author / Creator:Sartore-Bianchi, Andrea, MD ; Trusolino, Livio, MD ; Martino, Cosimo, PhD ; Bencardino, Katia, MD ; Lonardi, Sara, MD ; Bergamo, Francesca, MD ; Zagonel, Vittorina, MD ; Leone, Francesco, MD ; Depetris, Ilaria, MD ; Martinelli, Erika, MD ; Troiani, Teresa, MD ; Ciardiello, Fortunato, Prof ; Racca, Patrizia, MD ; Bertotti, Andrea, MD ; Siravegna, Giulia, MSc ; Torri, Valter, MD ; Amatu, Alessio, MD ; Ghezzi, Silvia, MSc ; Marrapese, Giovanna, PhD ; Palmeri, Laura, MD ; Valtorta, Emanuele, PhD ; Cassingena, Andrea, MSc ; Lauricella, Calogero, PhD ; Vanzulli, Angelo, MD ; Regge, Daniele, MD ; Veronese, Silvio, MSc ; Comoglio, Paolo M, Prof ; Bardelli, Alberto, PhD ; Marsoni, Silvia, Dr ; Siena, Salvatore, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.738-746
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Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition
Author / Creator:Verginelli, Federica ; Pisacane, Alberto ; Gambardella, Gennaro ; D’Ambrosio, Antonio ; Candiello, Ermes ; Ferrio, Marco ; Panero, Mara ; Casorzo, Laura ; Benvenuti, Silvia ; Cascardi, Eliano ; Senetta, Rebecca ; Geuna, Elena ; Ballabio, Andrea ; Montemurro, Filippo ; Sapino, Anna ; Comoglio, Paolo M. ; Boccaccio, Carla
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.2498-16, Article 2498
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Wild-type p53 controls cell motility and invasion by dual regulation of MET expression
Author / Creator:Hwang, Chang-Il ; Matoso, Andres ; Corney, David C ; Flesken-Nikitin, Andrea ; Körner, Stefanie ; Wang, Wei ; Boccaccio, Carla ; Thorgeirsson, Snorri S ; Comoglio, Paolo M ; Hermeking, Heiko ; Nikitin, Alexander Yu
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (34), p.14240-14245
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hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers
Author / Creator:Martinelli, Ilaria ; Modica, Chiara ; Chiriaco, Cristina ; Basilico, Cristina ; Hughes, James M. ; Corso, Simona ; Giordano, Silvia ; Comoglio, Paolo M. ; Vigna, Elisa
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2022-03, Vol.41 (1), p.112-17, Article 112
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MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells
Author / Creator:De Bacco, Francesca ; D'Ambrosio, Antonio ; Casanova, Elena ; Orzan, Francesca ; Neggia, Roberta ; Albano, Raffaella ; Verginelli, Federica ; Cominelli, Manuela ; Poliani, Pietro L ; Luraghi, Paolo ; Reato, Gigliola ; Pellegatta, Serena ; Finocchiaro, Gaetano ; Perera, Timothy ; Garibaldi, Elisabetta ; Gabriele, Pietro ; Comoglio, Paolo M ; Boccaccio, Carla
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2016-05, Vol.8 (5), p.550-568
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Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary
Author / Creator:Brundu, Serena ; Napolitano, Virginia ; Franzolin, Giulia ; Lo Cascio, Ettore ; Mastrantonio, Roberta ; Sardo, Gabriele ; Cascardi, Eliano ; Verginelli, Federica ; Sarnataro, Sergio ; Gambardella, Gennaro ; Pisacane, Alberto ; Arcovito, Alessandro ; Boccaccio, Carla ; Comoglio, Paolo M ; Giraudo, Enrico ; Tamagnone, Luca
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2023-03, Vol.15 (3), p.e16104-n/a
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A receptor-antibody hybrid hampering MET-driven metastatic spread
Author / Creator:Modica, Chiara ; Basilico, Cristina ; Chiriaco, Cristina ; Borrelli, Nicla ; Comoglio, Paolo M. ; Vigna, Elisa
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2021-01, Vol.40 (1), p.32-12, Article 32
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MicroRNA 483‐3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis
Author / Creator:Candiello, Ermes ; Reato, Gigliola ; Verginelli, Federica ; Gambardella, Gennaro ; D′Ambrosio, Antonio ; Calandra, Noemi ; Orzan, Francesca ; Iuliano, Antonella ; Albano, Raffaella ; Sassi, Francesco ; Luraghi, Paolo ; Comoglio, Paolo M. ; Bertotti, Andrea ; Trusolino, Livio ; Boccaccio, Carla
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2023-07, Vol.17 (7), p.1280-1301
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ArticlesPeer ReviewedFull Text
MET signalling: principles and functions in development, organ regeneration and cancer
Author / Creator:Trusolino, Livio ; Bertotti, Andrea ; Comoglio, Paolo M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2010-12, Vol.11 (12), p.834-848
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Cancer of Unknown Primary (CUP): genetic evidence for a novel nosological entity? A case report
Author / Creator:Benvenuti, Silvia ; Milan, Melissa ; Geuna, Elena ; Pisacane, Alberto ; Senetta, Rebecca ; Gambardella, Gennaro ; Stella, Giulia M ; Montemurro, Filippo ; Sapino, Anna ; Boccaccio, Carla ; Comoglio, Paolo M
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2020-07, Vol.12 (7), p.e11756-n/a
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ArticlesPeer ReviewedFull Text
Correction: hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers
Author / Creator:Martinelli, Ilaria ; Modica, Chiara ; Chiriaco, Cristina ; Basilico, Cristina ; Hughes, James M. ; Corso, Simona ; Giordano, Silvia ; Comoglio, Paolo M. ; Vigna, Elisa
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2022-05, Vol.41 (1), p.180-1, Article 180
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ArticlesPeer ReviewedFull Text
Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition
Author / Creator:Corso, Simona ; Ghiso, Elena ; Cepero, Virna ; Sierra, J RAFAEL ; Migliore, Cristina ; Bertotti, Andrea ; Trusolino, Livio ; Comoglio, Paolo M ; Giordano, Silvia
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2010-05, Vol.9 (1), p.121-121
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ArticlesPeer ReviewedFull Text
Prevention of hypoxia by myoglobin expression in human tumor cells promotes differentiation and inhibits metastasis
Author / Creator:Galluzzo, Maria ; Pennacchietti, Selma ; Rosano, Stefania ; Comoglio, Paolo M. ; Michieli, Paolo
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2009-04, Vol.119 (4), p.865-875
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Correction: Magic-Factor 1, a Partial Agonist of Met, Induces Muscle Hypertrophy by Protecting Myogenic Progenitors from Apoptosis
Author / Creator:Cassano, Marco ; Biressi, Stefano ; Finan, Amanda ; Benedetti, Laura ; Omes, Claudia ; Boratto, Renata ; Martin, Frank ; Allegretti, Marcello ; Broccoli, Vania ; Cusella De Angelis, Gabriella ; Comoglio, Paolo M. ; Basilico, Cristina ; Torrente, Yvan ; Michieli, Paolo ; Cossu, Giulio ; Sampaolesi, Maurilio
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-07, Vol.14 (7), p.e0220357
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ArticlesPeer ReviewedFull Text
Drug development of MET inhibitors: targeting oncogene addiction and expedience
Author / Creator:Comoglio, Paolo M. ; Giordano, Silvia ; Trusolino, Livio
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2008-06, Vol.7 (6), p.504-516
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Ab-Induced Ectodomain Shedding Mediates Hepatocyte Growth Factor Receptor down-Regulation and Hampers Biological Activity
Author / Creator:Petrelli, Annalisa ; Circosta, Paola ; Granziero, Luisa ; Mazzone, Massimiliano ; Pisacane, Alberto ; Fenoglio, Silvia ; Comoglio, Paolo M. ; Giordano, Silvia
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (13), p.5090-5095
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ArticlesPeer ReviewedFull Text
Invasive growth: a MET-driven genetic programme for cancer and stem cells
Author / Creator:Boccaccio, Carla ; Comoglio, Paolo M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2006-08, Vol.6 (8), p.637-645
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ArticlesPeer ReviewedFull Text
Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence
Author / Creator:Martin, Valentina ; Corso, Simona ; Comoglio, Paolo M. ; Giordano, Silvia
Publisher:United States: Elsevier B.V
Journal title:Molecular oncology, 2014-12, Vol.8 (8), p.1561-1574
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ArticlesPeer ReviewedFull Text
The Met tyrosine kinase receptor in development and cancer
Author / Creator:Gentile, Alessandra ; Trusolino, Livio ; Comoglio, Paolo M.
Publisher:Boston: Springer US
Journal title:Cancer and metastasis reviews, 2008-03, Vol.27 (1), p.85-94
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Showing 1 to 20 of 76 results

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Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy

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Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-l...

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Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition

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Wild-type p53 controls cell motility and invasion by dual regulation of MET expression

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hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers

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MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells

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Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary

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A receptor-antibody hybrid hampering MET-driven metastatic spread

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MicroRNA 483‐3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis

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MET signalling: principles and functions in development, organ regeneration and cancer

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Cancer of Unknown Primary (CUP): genetic evidence for a novel nosological entity? A case report

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Correction: hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers

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Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition

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Prevention of hypoxia by myoglobin expression in human tumor cells promotes differentiation and inhibits metastasis

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Correction: Magic-Factor 1, a Partial Agonist of Met, Induces Muscle Hypertrophy by Protecting Myogenic Progenitors from Apoptosis

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Drug development of MET inhibitors: targeting oncogene addiction and expedience

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Ab-Induced Ectodomain Shedding Mediates Hepatocyte Growth Factor Receptor down-Regulation and Hampers Biological Activity

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Invasive growth: a MET-driven genetic programme for cancer and stem cells

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Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence

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The Met tyrosine kinase receptor in development and cancer

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