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ArticlesPeer ReviewedFull Text
Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
Author / Creator:Strowitzki, Moritz ; Cummins, Eoin ; Taylor, Cormac
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2019-04, Vol.8 (5), p.384
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Regulation of IL-1β–induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways
Author / Creator:Scholz, Carsten C. ; Cavadas, Miguel A. S. ; Tambuwala, Murtaza M. ; Hams, Emily ; Rodríguez, Javier ; von Kriegsheim, Alex ; Cotter, Philip ; Bruning, Ulrike ; Fallon, Padraic G. ; Cheong, Alex ; Cummins, Eoin P. ; Taylor, Cormac T.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (46), p.18490-18495
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Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity
Author / Creator:Cummins, Eoin P. ; Berra, Edurne ; Comerford, Katrina M. ; Ginouves, Amandine ; Fitzgerald, Kathleen T. ; Seeballuck, Fergal ; Godson, Catherine ; Nielsen, Jens E. ; Moynagh, Paul ; Pouyssegur, Jacques ; Taylor, Cormac T.
Publisher:National Acad Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (48), p.18154-18159
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FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1
Author / Creator:Scholz, Carsten C. ; Rodriguez, Javier ; Pickel, Christina ; Burr, Stephen ; Fabrizio, Jacqueline-alba ; Nolan, Karen A. ; Spielmann, Patrick ; Cavadas, Miguel A. S. ; Crifo, Bianca ; Halligan, Doug N. ; Nathan, James A. ; Peet, Daniel J. ; Wenger, Roland H. ; Von Kriegsheim, Alex ; Cummins, Eoin P. ; Taylor, Cormac T.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2016-01, Vol.14 (1), p.e1002347
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REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia
Author / Creator:Cavadas, Miguel A. S. ; Mesnieres, Marion ; Crifo, Bianca ; Manresa, Mario C. ; Selfridge, Andrew C. ; Scholz, Carsten C. ; Cummins, Eoin P. ; Cheong, Alex ; Taylor, Cormac T.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-12, Vol.5 (1), p.17851-17851, Article 17851
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REST is a hypoxia-responsive transcriptional repressor
Author / Creator:Cavadas, Miguel A. S. ; Mesnieres, Marion ; Crifo, Bianca ; Manresa, Mario C. ; Selfridge, Andrew C. ; Keogh, Ciara E. ; Fabian, Zsolt ; Scholz, Carsten C. ; Nolan, Karen A. ; Rocha, Liliane M. A. ; Tambuwala, Murtaza M. ; Brown, Stuart ; Wdowicz, Anita ; Corbett, Danielle ; Murphy, Keith J. ; Godson, Catherine ; Cummins, Eoin P. ; Taylor, Cormac T. ; Cheong, Alex
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-08, Vol.6 (1), p.31355, Article 31355
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PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells
Author / Creator:O'Hagan, Kathleen A ; Cocchiglia, Sinead ; Zhdanov, Alexander V ; Tambawala, Murtaza M ; Cummins, Eoin P ; Monfared, Mona ; Agbor, Terence A ; Garvey, John F ; Papkovsky, Dmitri B ; Taylor, Cormac T ; Allan, Bernard B
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (7), p.2188-2193
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ArticlesPeer ReviewedFull Text
Hypoxia-dependent regulation of inflammatory pathways in immune cells
Author / Creator:Taylor, Cormac T. ; Doherty, Glen ; Fallon, Padraic G. ; Cummins, Eoin P.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-10, Vol.126 (10), p.3716-3724
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Carbon dioxide-sensing in organisms and its implications for human disease
Author / Creator:Cummins, Eoin P ; Selfridge, Andrew C ; Sporn, Peter H ; Sznajder, Jacob I ; Taylor, Cormac T
Publisher:Basel: Springer-Verlag
Journal title:Cellular and molecular life sciences : CMLS, 2014-03, Vol.71 (5), p.831-845
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ArticlesPeer ReviewedFull Text
Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia
Author / Creator:Phelan, David E. ; Reddan, Ben ; Shigemura, Masahiko ; Sznajder, Jacob I. ; Crean, Daniel ; Cummins, Eoin P.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-03, Vol.25 (5), p.2852
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ArticlesPeer ReviewedFull Text
Hypoxia-responsive transcription factors
Author / Creator:Cummins, Eoin P. ; Taylor, Cormac T.
Publisher:Germany: Springer Nature B.V
Journal title:Pflügers Archiv, 2005-09, Vol.450 (6), p.363-371
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Hydroxylases as therapeutic targets in inflammatory bowel disease
Author / Creator:Cummins, Eoin P ; Doherty, Glen A ; Taylor, Cormac T
Publisher:New York: Nature Publishing Group US
Journal title:Laboratory investigation, 2013-04, Vol.93 (4), p.378-383
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ArticlesPeer ReviewedFull Text
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion
Author / Creator:McGettrick, Anne F. ; Corcoran, Sarah E. ; Barry, Paul J. G. ; McFarland, Jennifer ; Crès, Cécile ; Curtis, Anne M. ; Franklin, Edward ; Corr, Sinéad C. ; Mok, K. Hun ; Cummins, Eoin P. ; Taylor, Cormac T. ; O’Neill, Luke A. J. ; Nolan, Derek P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (48), p.E7778-E7787
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ArticlesPeer ReviewedFull Text
Hypoxia Activates NF-κB–Dependent Gene Expression Through the Canonical Signaling Pathway
Author / Creator:Oliver, Kathryn M. ; Garvey, John F. ; Ng, Chin Teck ; Veale, Douglas J. ; Fearon, Ursula ; Cummins, Eoin P. ; Taylor, Cormac T.
Publisher:Mary Ann Liebert, Inc
Journal title:Antioxidants & redox signaling, 2009-09, Vol.11 (9), p.2057-2064
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ArticlesPeer ReviewedFull Text
Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases
Author / Creator:Oliver, Kathryn M ; Taylor, Cormac T ; Cummins, Eoin P
Publisher:BioMed Central Ltd
Journal title:Arthritis research & therapy, 2009-01, Vol.11 (1), p.215-215
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HIF-2α - a mediator of stem cell altruism?
Author / Creator:Cummins, Eoin P
Publisher:England: BioMed Central
Journal title:Stem cell research & therapy, 2012-12, Vol.3 (6), p.52-52, Article 52
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ArticlesPeer ReviewedFull Text
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1a and glycolysis in macrophages as a mechanism of innate immune evasion
Author / Creator:McGettrick, Anne F ; Corcoran, Sarah E ; Barry, Paul JG ; McFarland, Jennifer ; Crès, Cécile ; Curtis, Anne M ; Franklin, Edward ; Corr, Sinéad C ; Mok, K Hun ; Cummins, Eoin P ; Taylor, Cormac T ; O'Neill, Luke AJ ; Nolan, Derek P
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (48), p.E7778-E7778
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ArticlesPeer ReviewedFull Text
FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1: e1002347
Author / Creator:Scholz, Carsten C ; Rodriguez, Javier ; Pickel, Christina ; Burr, Stephen ; Fabrizio, Jacqueline-alba ; Nolan, Karen A ; Spielmann, Patrick ; Cavadas, Miguel AS ; Crifo, Bianca ; Halligan, Doug N ; Nathan, James A ; Peet, Daniel J ; Wenger, Roland H ; Kriegsheim, Alex Von ; Cummins, Eoin P ; Taylor, Cormac T
Publisher:San Francisco: Public Library of Science
Journal title:PLoS biology, 2016-01, Vol.14 (1)
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ArticlesPeer ReviewedFull Text
Regulation of IL-1[Beta]-induced NF-[kappa]B by hydroxylases links key hypoxic and inflammatory signaling pathways
Author / Creator:Scholz, Carsten C ; Cavadas, Miguel A S ; Tambuwala, Murtaza M ; Hams, Emily ; Rodríguez, Javier ; von Kriegsheim, Alex ; Cotter, Philip ; Bruning, Ulrike ; Fallon, Padraic G ; Cheong, Alex ; Cummins, Eoin P ; Taylor, Cormac T
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (46), p.18490
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ArticlesPeer ReviewedFull Text
Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases
Author / Creator:Oliver, Kathryn M ; Taylor, Cormac T ; Cummins, Eoin P
Publisher:England: National Library of Medicine - MEDLINE Abstracts
Journal title:Arthritis research & therapy, 2009, Vol.11 (1), p.215
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Showing 1 to 20 of 29 results

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Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?

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Regulation of IL-1β–induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways

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Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity

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FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

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REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia

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REST is a hypoxia-responsive transcriptional repressor

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PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells

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Hypoxia-dependent regulation of inflammatory pathways in immune cells

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Carbon dioxide-sensing in organisms and its implications for human disease

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Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia

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Hypoxia-responsive transcription factors

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Hydroxylases as therapeutic targets in inflammatory bowel disease

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Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion

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Hypoxia Activates NF-κB–Dependent Gene Expression Through the Canonical Signaling Pathway

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Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases

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HIF-2α - a mediator of stem cell altruism?

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Trypanosoma brucei metabolite indolepyruvate decreases HIF-1a and glycolysis in macrophages as a mechanism of innate immune evasion

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FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1: e1002347

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Regulation of IL-1[Beta]-induced NF-[kappa]B by hydroxylases links key hypoxic and inflammatory signaling pathways

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Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases

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