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ArticlesPeer ReviewedFull Text
H₂S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase
Author / Creator:Yang, Guangdong ; Wu, Lingyun ; Jiang, Bo ; Yang, Wei ; Qi, Jiansong ; Cao, Kun ; Meng, Qinghe ; Mustafa, Asif K ; Mu, Weitong ; Zhang, Shengming ; Snyder, Solomon H ; Wang, Rui
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-10, Vol.322 (5901), p.587-590
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Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease
Author / Creator:Paul, Bindu D. ; Sbodio, Juan I. ; Xu, Risheng ; Vandiver, M. Scott ; Cha, Jiyoung Y. ; Snowman, Adele M. ; Snyder, Solomon H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-05, Vol.509 (7498), p.96-100
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Cystathionine‑γ‑lyase promotes the metastasis of breast cancer via the VEGF signaling pathway
Author / Creator:Wang, Lupeng ; Shi, Haimei ; Liu, Ya ; Zhang, Weiyuan ; Duan, Xiaofang ; Li, Ming ; Shi, Xiaoyan ; Wang, Tianxiao
Publisher:Athens: Spandidos Publications UK Ltd
Journal title:International journal of oncology, 2019-08, Vol.55 (2), p.473-487
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Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism
Author / Creator:Araki, Shoma ; Takata, Tsuyoshi ; Ono, Katsuhiko ; Sawa, Tomohiro ; Kasamatsu, Shingo ; Ihara, Hideshi ; Kumagai, Yoshito ; Akaike, Takaaki ; Watanabe, Yasuo ; Tsuchiya, Yukihiro
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-06, Vol.24 (12), p.9982
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Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators—Inhibitors of Bacterial Cystathionine γ-Lyase
Author / Creator:Kuzovlev, Andrey S. ; Zybalov, Mikhail D. ; Golovin, Andrey V. ; Gureev, Maxim A. ; Kasatkina, Mariia A. ; Biryukov, Mikhail V. ; Belik, Albina R. ; Silonov, Sergey A. ; Yunin, Maxim A. ; Zigangirova, Nailya A. ; Reshetnikov, Vasiliy V. ; Isakova, Yulia E. ; Porozov, Yuri B. ; Ivanov, Roman A.
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2023-11, Vol.24 (22), p.16331
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Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation
Author / Creator:Echizen, Honami ; Hanaoka, Kenjiro ; Shimamoto, Kazuhito ; Hibi, Ryota ; Toma-Fukai, Sachiko ; Ohno, Hisashi ; Sasaki, Eita ; Komatsu, Toru ; Ueno, Tasuku ; Tsuchiya, Yukihiro ; Watanabe, Yasuo ; Otsuka, Takao ; Saito, Hiroaki ; Nagatoishi, Satoru ; Tsumoto, Kouhei ; Kojima, Hirotatsu ; Okabe, Takayoshi ; Shimizu, Toshiyuki ; Urano, Yasuteru
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-09, Vol.13 (1), p.16456-16456, Article 16456
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Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa
Author / Creator:Pedretti, Marco ; Fernández-Rodríguez, Carmen ; Conter, Carolina ; Oyenarte, Iker ; Favretto, Filippo ; di Matteo, Adele ; Dominici, Paola ; Petrosino, Maria ; Martinez-Chantar, Maria Luz ; Majtan, Tomas ; Astegno, Alessandra ; Martínez-Cruz, Luis Alfonso
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-04, Vol.14 (1), p.9364-9364, Article 9364
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Honokiol ameliorates angiotensin II‐induced hypertension and endothelial dysfunction by inhibiting HDAC6‐mediated cystathionine γ‐lyase degradation
Author / Creator:Chi, Zhexi ; Le, Truc Phan Hoang ; Lee, Sang Ki ; Guo, Erling ; Kim, Dongsoo ; Lee, Sanha ; Seo, Seung‐Yong ; Lee, Sook Young ; Kim, Jae Hyung ; Lee, Sang Yoon
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-09, Vol.24 (18), p.10663-10676
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Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function
Author / Creator:CHEN, LIANGYU ; LI, XINXING ; LIU, LIBO ; YU, BO ; XUE, YIXUE ; LIU, YUNHUI
Publisher:Greece: D.A. Spandidos
Journal title:Oncology reports, 2015-03, Vol.33 (3), p.1465-1474
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Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma
Author / Creator:Zhang, Qianqian ; Gao, Yingran ; Zhang, Yanxia ; Jing, Mirong ; Wang, Di ; Wang, Yizhen ; Khattak, Saadullah ; Qi, Huiwen ; Cai, Chunbo ; Zhang, Jing ; Ngowi, Ebenezeri Erasto ; Khan, Nazeer Hussain ; Li, Tao ; Ji, Ailing ; Jiang, Qiying ; Ji, Xinying ; Li, Yanzhang ; Wu, Dongdong
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2022-12, Vol.41 (49), p.5238-5252
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6-Bromoindole- and 6-Bromoindazole-Based Inhibitors of Bacterial Cystathionine γ-Lyase Containing 3-Aminothiophene-2-Carboxylate Moiety
Author / Creator:Novikov, Roman A. ; Platonov, Dmitry N. ; Belyy, Alexander Yu ; Potapov, Konstantin V. ; Novikov, Maxim A. ; Tomilov, Yury V. ; Kechko, Olga I. ; Seregina, Tatiana A. ; Zemskaya, Anastasia S. ; Solyev, Pavel N. ; Mitkevich, Vladimir A.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-01, Vol.30 (2), p.388
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Synthesis of the Indole-Based Inhibitors of Bacterial Cystathionine γ-Lyase NL1-NL3
Author / Creator:Potapov, Konstantin V. ; Novikov, Roman A. ; Novikov, Maxim A. ; Solyev, Pavel N. ; Tomilov, Yury V. ; Kochetkov, Sergey N. ; Makarov, Alexander A. ; Mitkevich, Vladimir A.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-04, Vol.28 (8), p.3568
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Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis
Author / Creator:Matoba, Yasuyuki ; Noda, Masafumi ; Yoshida, Tomoki ; Oda, Kosuke ; Ezumi, Yuka ; Yasutake, Chiaki ; Izuhara-Kihara, Hisae ; Danshiitsoodol, Narandarai ; Kumagai, Takanori ; Sugiyama, Masanori
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.14886-14886, Article 14886
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E2β Stimulates Ovine Uterine Artery Endothelial Cell H2S Production in vitro by Estrogen Receptor-Dependent Upregulation of Cystathionine β-Synthase and Cystathionine γ -Lyase Expression
Author / Creator:Lechuga, Thomas J ; Qi, Qian-rong ; Kim, Theresa ; Magness, Ronald R ; Chen, Dong-bao
Publisher:United States: Society for the Study of Reproduction
Journal title:Biology of reproduction, 2019-02, Vol.100 (2), p.514-522
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Downregulation of cystathionine β‐synthase and cystathionine γ‐lyase expression stimulates inflammation in kidney ischemia–reperfusion injury
Author / Creator:Wang, Pengqi ; Isaak, Cara K. ; Siow, Yaw L. ; O, Karmin
Publisher:United States: John Wiley & Sons, Inc
Journal title:Physiological reports, 2014-12, Vol.2 (12), p.e12251-n/a
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Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase—An Animal Model of Cystathioninuria
Author / Creator:Akahoshi, Noriyuki ; Handa, Hiroki ; Takemoto, Rintaro ; Kamata, Shotaro ; Yoshida, Masahide ; Onaka, Tatsushi ; Ishii, Isao
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-07, Vol.20 (14), p.3507
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Tyrosol Attenuates High Fat Diet-Induced Hepatic Oxidative Stress: Potential Involvement of Cystathionine β-Synthase and Cystathionine γ-Lyase
Author / Creator:Sarna, Lindsei K. ; Sid, Victoria ; Wang, Pengqi ; Siow, Yaw L. ; House, James D. ; O, Karmin
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Lipids, 2016-05, Vol.51 (5), p.583-590
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Cystathionine-γ-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis
Author / Creator:Wu, Weijun ; Qin, Ming ; Jia, Wanwan ; Huang, Zheng ; Li, Zhongzheng ; Yang, Di ; Huang, Mengwei ; Xiao, Chenxi ; Long, Fen ; Mao, Jianchun ; Moore, Philip K. ; Liu, Xinhua ; Zhu, Yi Zhun
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2019-08, Vol.16 (8), p.694-705
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Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation
Author / Creator:Cornwell, Alex ; Fedotova, Samantha ; Cowan, Sara ; Badiei, Alireza
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022-12, Vol.17 (12), p.e0278910
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Involvement of NF‐κB in the upregulation of cystathionine‐γ‐lyase, a hydrogen sulfide‐forming enzyme, and bladder pain accompanying cystitis in mice
Author / Creator:Ozaki, Tomoka ; Tsubota, Maho ; Sekiguchi, Fumiko ; Kawabata, Atsufumi
Publisher:Australia: Wiley Subscription Services, Inc
Journal title:Clinical and experimental pharmacology & physiology, 2018-04, Vol.45 (4), p.355-361
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H₂S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase

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Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease

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Cystathionine‑γ‑lyase promotes the metastasis of breast cancer via the VEGF signaling pathway

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Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism

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Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators—Inhibitors of Bacterial Cystathionine γ-Lyase

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Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation

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Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa

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Honokiol ameliorates angiotensin II‐induced hypertension and endothelial dysfunction by inhibiting HDAC6‐mediated cystathionine γ‐lyase degradation

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Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function

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Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma

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6-Bromoindole- and 6-Bromoindazole-Based Inhibitors of Bacterial Cystathionine γ-Lyase Containing 3-Aminothiophene-2-Carboxylate Moiety

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Synthesis of the Indole-Based Inhibitors of Bacterial Cystathionine γ-Lyase NL1-NL3

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Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis

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E2β Stimulates Ovine Uterine Artery Endothelial Cell H2S Production in vitro by Estrogen Receptor-Dependent Upregulation of Cystathionine β-Synthase and Cystathionine γ -Lyase Expression

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Downregulation of cystathionine β‐synthase and cystathionine γ‐lyase expression stimulates inflammation in kidney ischemia–reperfusion injury

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Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase—An Animal Model of Cystathioninuria

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Tyrosol Attenuates High Fat Diet-Induced Hepatic Oxidative Stress: Potential Involvement of Cystathionine β-Synthase and Cystathionine γ-Lyase

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Cystathionine-γ-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis

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Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation

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Involvement of NF‐κB in the upregulation of cystathionine‐γ‐lyase, a hydrogen sulfide‐forming enzyme, and bladder pain accompanying cystitis in mice

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