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Pyroptotic macrophages stimulate the SARS-CoV-2-associated cytokine storm
Author / Creator:Zhang, Jinghe ; Wu, Haibo ; Yao, XiaoHong ; Zhang, Dingyu ; Zhou, Yonggang ; Fu, Binqing ; Wang, Wei ; Li, Heng ; Wang, Zhe ; Hu, Ziming ; Ren, Yong ; Sun, Rui ; Tian, Zhigang ; Bian, Xiuwu ; Wei, Haiming
Publisher:China: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2021-05, Vol.18 (5), p.1305-1307
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Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis
Author / Creator:Pan, Xiu-wu ; Xu, Da ; Zhang, Hao ; Zhou, Wang ; Wang, Lin-hui ; Cui, Xin-gang
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Intensive care medicine, 2020-06, Vol.46 (6), p.1114-1116
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Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors
Author / Creator:Han, Huan ; Ma, Qingfeng ; Li, Cong ; Liu, Rui ; Zhao, Li ; Wang, Wei ; Zhang, Pingan ; Liu, Xinghui ; Gao, Guosheng ; Liu, Fang ; Jiang, Yingan ; Cheng, Xiaoming ; Zhu, Chengliang ; Xia, Yuchen
Publisher:United States: Taylor & Francis
Journal title:Emerging microbes & infections, 2020-01, Vol.9 (1), p.1123-1130
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Preliminary predictive criteria for COVID-19 cytokine storm
Author / Creator:Gallucci, Marcello ; Dass, Chandra ; Zhang, Xinyan ; Criner, Gerard J ; Pathak, Abhijit S ; Rastogi, Abhinav ; Satti, Aditi ; Pandya, Aloknath ; Goldberg, Amy ; Kambo, Amy ; Vaidya, Anjali ; Lau, Arthur ; Lawrence, Brent ; Corso, Brittany ; Grabianowski, Carla ; Bakhos, Charles ; Erkmen, Cherie ; Lin, Chih-ru ; Burks, Christopher T ; Raab, Claire ; Simon, Daniele ; Ambrose, David ; Gillman, Debra ; Dominguez, Eduardo ; Randhawa, Ekam ; Randhawa, Ekamjeet ; Male, Eneida ; Narewski, Erin ; Kueppers, Frederich ; Garfield, Jamie ; Criner, Gerard ; Marmolejos, Ginny ; Gordon, Matthew ; Fernandez, Gustavo ; Simborio, Hannah ; Scott, Harwood ; Lee, Iris Jung-won ; Tang, Jessica ; Gonzalez, Jeyssa ; Wu, Jichuan ; Murrett, Jim ; Beros, Joanna ; Travaline, John M. ; Varghese, Jolly ; Senchak, Jordan ; Lambert, Joseph ; Ramzy, Joseph ; Kennedy, Kaitlin ; Ahmed, Karim B ; Shenoy, Karthik ; Brennan, Kathleen ; Kilpatrick, Laurie ; Brent, Lawrence ; Kerper, Margaret ; Marcinkienwicz, Mariola ; Aksoy, Mark ; Wolfson, Marla ; Marron, Robert ; Zantah, Massa ; Gannon, Michael ; Jacobs, Michael ; Mandal, Mira ; Marchetti, Nathaniel ; Xander, Nathaniel ; Nadpara, Neil ; Desai, Nicole ; Shigemura, Norihisa ; Rehbini, Ohoud ; Desai, Parag ; Rali, Parth ; Varghese, Priju ; Dubal, Puja ; Armbruster, Rebecca A ; Thomas, Rogers ; Soans, Rohit ; Petrov, Roman ; Prosniak, Roman ; Bhutani, Ruchi ; Townsend, Ryan ; Krachman, Samuel ; Dhungana, Santosh ; Hoang, Sarah ; Benny, Shelu ; George, Sheril ; Sun, Shuang ; Srivastava-Malhotra, Shubhra ; Spivack, Stephanie ; Priest, Stephen ; Houser, Steven ; Verga, Steven ; Bolla, Sudhir ; Johnson, Sylvia ; Shariff, Tahseen ; Hooper, Thomas ; Reed, Tony S. ; Ku, Tse-Shuen ; Sajjan, Uma ; Chatila, Wissam ; Li, Wuyan ; Dorey-Stein, Zachariah
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2021-01, Vol.80 (1), p.88-95
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SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells
Author / Creator:Patra, Tapas ; Meyer, Keith ; Geerling, Lizzie ; Isbell, T. Scott ; Hoft, Daniel F. ; Brien, James ; Pinto, Amelia K. ; Ray, Ratna B. ; Ray, Ranjit
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-12, Vol.16 (12), p.e1009128-e1009128
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Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform tria...
Author / Creator:Butler, Christopher C ; Dorward, Jienchi ; Yu, Ly-Mee ; Gbinigie, Oghenekome ; Hayward, Gail ; Saville, Benjamin R ; Van Hecke, Oliver ; Berry, Nick ; Detry, Michelle ; Saunders, Christina ; Fitzgerald, Mark ; Harris, Victoria ; Patel, Mahendra G ; de Lusignan, Simon ; Ogburn, Emma ; Evans, Philip H ; Thomas, Nicholas PB ; Hobbs, FD Richard
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2021-03, Vol.397 (10279), p.1063-1074
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Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
Author / Creator:Vanderbeke, L. ; Van Mol, P. ; Van Herck, Y. ; De Smet, F. ; Humblet-Baron, S. ; Martinod, K. ; Antoranz, A. ; Arijs, I. ; Boeckx, B. ; Bosisio, F. M. ; Casaer, M. ; Dauwe, D. ; De Wever, W. ; Dooms, C. ; Dreesen, E. ; Emmaneel, A. ; Filtjens, J. ; Gouwy, M. ; Gunst, J. ; Hermans, G. ; Jansen, S. ; Lagrou, K. ; Liston, A. ; Lorent, N. ; Meersseman, P. ; Mercier, T. ; Neyts, J. ; Odent, J. ; Panovska, D. ; Penttila, P. A. ; Pollet, E. ; Proost, P. ; Qian, J. ; Quintelier, K. ; Raes, J. ; Rex, S. ; Saeys, Y. ; Sprooten, J. ; Tejpar, S. ; Testelmans, D. ; Thevissen, K. ; Van Buyten, T. ; Vandenhaute, J. ; Van Gassen, S. ; Velásquez Pereira, L. C. ; Vos, R. ; Weynand, B. ; Wilmer, A. ; Yserbyt, J. ; Garg, A. D. ; Matthys, P. ; Wouters, C. ; Lambrechts, D. ; Wauters, E. ; Wauters, J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4117-4117, Article 4117
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ArticlesPeer ReviewedFull Text
Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study
Author / Creator:Ramiro, Sofia ; Mostard, Rémy L M ; Magro-Checa, César ; van Dongen, Christel M P ; Dormans, Tom ; Buijs, Jacqueline ; Gronenschild, Michiel ; de Kruif, Martijn D ; van Haren, Eric H J ; van Kraaij, Tom ; Leers, Mathie P G ; Peeters, Ralph ; Wong, Dennis R ; Landewé, Robert B M
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2020-09, Vol.79 (9), p.1143-1151
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The microbial coinfection in COVID-19
Author / Creator:Chen, Xi ; Liao, Binyou ; Cheng, Lei ; Peng, Xian ; Xu, Xin ; Li, Yuqing ; Hu, Tao ; Li, Jiyao ; Zhou, Xuedong ; Ren, Biao
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Applied microbiology and biotechnology, 2020-09, Vol.104 (18), p.7777-7785
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The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”
Author / Creator:Meftahi, Gholam Hossein ; Jangravi, Zohreh ; Sahraei, Hedayat ; Bahari, Zahra
Publisher:Cham: Springer International Publishing
Journal title:Inflammation research, 2020-09, Vol.69 (9), p.825-839
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The Janus kinase 1/2 inhibitor ruxolitinib in COVID-19 with severe systemic hyperinflammation
Author / Creator:La Rosée, F. ; Bremer, H. C. ; Gehrke, I. ; Kehr, A. ; Hochhaus, A. ; Birndt, S. ; Fellhauer, M. ; Henkes, M. ; Kumle, B. ; Russo, S. G. ; La Rosée, P.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2020-07, Vol.34 (7), p.1805-1815
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IP-10 and MCP-1 as biomarkers associated with disease severity of COVID-19
Author / Creator:Chen, Yu ; Wang, Jinglan ; Liu, Chenxi ; Su, Longxiang ; Zhang, Dong ; Fan, Junping ; Yang, Yanli ; Xiao, Meng ; Xie, Jing ; Xu, Yingchun ; Li, Yongzhe ; Zhang, Shuyang
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2020-10, Vol.26 (1), p.97-97, Article 97
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COVID-19 and the role of chronic inflammation in patients with obesity
Author / Creator:Chiappetta, Sonja ; Sharma, Arya M. ; Bottino, Vincenzo ; Stier, Christine
Publisher:London: Nature Publishing Group UK
Journal title:International Journal of Obesity, 2020-08, Vol.44 (8), p.1790-1792
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Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients
Author / Creator:Chen, Liting ; Long, Xiaolu ; Xu, Qian ; Tan, Jiaqi ; Wang, Gaoxiang ; Cao, Yang ; Wei, Jia ; Luo, Hui ; Zhu, Hui ; Huang, Liang ; Meng, Fankai ; Huang, Lifang ; Wang, Na ; Zhou, Xiaoxi ; Zhao, Lei ; Chen, Xing ; Mao, Zekai ; Chen, Caixia ; Li, Zhen ; Sun, Ziyong ; Zhao, Jianping ; Wang, Daowen ; Huang, Gang ; Wang, Wei ; Zhou, Jianfeng
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2020-09, Vol.17 (9), p.992-994
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Mini-Review on the Roles of Vitamin C, Vitamin D, and Selenium in the Immune System against COVID-19
Author / Creator:Bae, Minkyung ; Kim, Hyeyoung
Publisher:Switzerland
Journal title:Molecules (Basel, Switzerland), 2020-11, Vol.25 (22)
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Hypoxia, HIF-1α, and COVID-19: from pathogenic factors to potential therapeutic targets
Author / Creator:Serebrovska, Zoya O. ; Chong, Elisa Y. ; Serebrovska, Tetiana V. ; Tumanovska, Lesia V. ; Xi, Lei
Publisher:Singapore: Springer Singapore
Journal title:Acta pharmacologica Sinica, 2020-12, Vol.41 (12), p.1539-1546
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COVID 19: a clue from innate immunity
Author / Creator:Birra, Domenico ; Benucci, Maurizio ; Landolfi, Luigi ; Merchionda, Anna ; Loi, Gabriella ; Amato, Patrizia ; Licata, Gaetano ; Quartuccio, Luca ; Triggiani, Massimo ; Moscato, Paolo
Publisher:New York: Springer US
Journal title:Immunologic research, 2020-06, Vol.68 (3), p.161-168
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After 62 years of regulating immunity, dexamethasone meets COVID-19
Author / Creator:Cain, Derek W. ; Cidlowski, John A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2020-10, Vol.20 (10), p.587-588
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SARS-CoV-2 infection and overactivation of Nlrp3 inflammasome as a trigger of cytokine “storm” and risk factor for damage of hematopoietic stem cells
Author / Creator:Ratajczak, Mariusz Z. ; Kucia, Magda
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2020-07, Vol.34 (7), p.1726-1729
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Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure—a cautionary case series
Author / Creator:Stallmach, Andreas ; Kortgen, Andreas ; Gonnert, Falk ; Coldewey, Sina M. ; Reuken, Philipp ; Bauer, Michael
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2020-07, Vol.24 (1), p.444-3, Article 444
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Pyroptotic macrophages stimulate the SARS-CoV-2-associated cytokine storm

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Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis

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Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

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Preliminary predictive criteria for COVID-19 cytokine storm

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SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells

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Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform tria...

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Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

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Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study

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The microbial coinfection in COVID-19

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The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

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The Janus kinase 1/2 inhibitor ruxolitinib in COVID-19 with severe systemic hyperinflammation

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IP-10 and MCP-1 as biomarkers associated with disease severity of COVID-19

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COVID-19 and the role of chronic inflammation in patients with obesity

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Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients

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Mini-Review on the Roles of Vitamin C, Vitamin D, and Selenium in the Immune System against COVID-19

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Hypoxia, HIF-1α, and COVID-19: from pathogenic factors to potential therapeutic targets

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COVID 19: a clue from innate immunity

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After 62 years of regulating immunity, dexamethasone meets COVID-19

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SARS-CoV-2 infection and overactivation of Nlrp3 inflammasome as a trigger of cytokine “storm” and risk factor for damage of hematopoietic stem cells

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Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure—a cautionary case series

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