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Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
Author / Creator:Coni, Sonia ; Serrao, Silvia Maria ; Yurtsever, Zuleyha Nihan ; Di Magno, Laura ; Bordone, Rosa ; Bertani, Camilla ; Licursi, Valerio ; Ianniello, Zaira ; Infante, Paola ; Moretti, Marta ; Petroni, Marialaura ; Guerrieri, Francesca ; Fatica, Alessandro ; Macone, Alberto ; De Smaele, Enrico ; Di Marcotullio, Lucia ; Giannini, Giuseppe ; Maroder, Marella ; Agostinelli, Enzo ; Canettieri, Gianluca
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-12, Vol.11 (12), p.1045-1045, Article 1045
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Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons
Author / Creator:Akman, Muhlis ; Belisario, Dimas Carolina ; Salaroglio, Iris Chiara ; Kopecka, Joanna ; Donadelli, Massimo ; De Smaele, Enrico ; Riganti, Chiara
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2021-01, Vol.40 (1), p.28-28, Article 28
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Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes
Author / Creator:De Blasio, Carlo ; Verma, Nagendra ; Moretti, Marta ; Cialfi, Samantha ; Zonfrilli, Azzurra ; Franchitto, Matteo ; Truglio, Federica ; De Smaele, Enrico ; Ichijo, Hidenori ; Naguro, Isao ; Screpanti, Isabella ; Talora, Claudio
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2021-04, Vol.7 (1), p.1-8, Article 75
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The emerging role of the KCTD proteins in cancer
Author / Creator:Angrisani, Annapaola ; Di Fiore, Annamaria ; De Smaele, Enrico ; Moretti, Marta
Publisher:England: BioMed Central
Journal title:Cell communication and signaling, 2021-05, Vol.19 (1), p.56-56, Article 56
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Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance
Author / Creator:Belisario, Dimas Carolina ; Kopecka, Joanna ; Pasino, Martina ; Akman, Muhlis ; De Smaele, Enrico ; Donadelli, Massimo ; Riganti, Chiara
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-12, Vol.9 (12), p.2598
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Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells
Author / Creator:Po, Agnese ; Citarella, Anna ; Catanzaro, Giuseppina ; Besharat, Zein Mersini ; Trocchianesi, Sofia ; Gianno, Francesca ; Sabato, Claudia ; Moretti, Marta ; De Smaele, Enrico ; Vacca, Alessandra ; Fiori, Micol Eleonora ; Ferretti, Elisabetta
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-08, Vol.10 (1), p.13988, Article 13988
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SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment
Author / Creator:Molfetta, Rosa ; Lecce, Mario ; Milito, Nadia D. ; Putro, Erisa ; Pietropaolo, Giuseppe ; Marangio, Caterina ; Scarno, Gianluca ; Moretti, Marta ; De Smaele, Enrico ; Santini, Tiziana ; Bernardini, Giovanni ; Sciumè, Giuseppe ; Santoni, Angela ; Paolini, Rossella
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2023-09, Vol.14 (9), p.616-616, Article 616
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Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
Author / Creator:Infante, Paola ; Faedda, Roberta ; Bernardi, Flavia ; Bufalieri, Francesca ; Lospinoso Severini, Ludovica ; Alfonsi, Romina ; Mazzà, Daniela ; Siler, Mariangela ; Coni, Sonia ; Po, Agnese ; Petroni, Marialaura ; Ferretti, Elisabetta ; Mori, Mattia ; De Smaele, Enrico ; Canettieri, Gianluca ; Capalbo, Carlo ; Maroder, Marella ; Screpanti, Isabella ; Kool, Marcel ; Pfister, Stefan M. ; Guardavaccaro, Daniele ; Gulino, Alberto ; Di Marcotullio, Lucia
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-03, Vol.9 (1), p.976-17, Article 976
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ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Author / Creator:Bufalieri, Francesca ; Infante, Paola ; Bernardi, Flavia ; Caimano, Miriam ; Romania, Paolo ; Moretti, Marta ; Lospinoso Severini, Ludovica ; Talbot, Julie ; Melaiu, Ombretta ; Tanori, Mirella ; Di Magno, Laura ; Bellavia, Diana ; Capalbo, Carlo ; Puget, Stéphanie ; De Smaele, Enrico ; Canettieri, Gianluca ; Guardavaccaro, Daniele ; Busino, Luca ; Peschiaroli, Angelo ; Pazzaglia, Simonetta ; Giannini, Giuseppe ; Melino, Gerry ; Locatelli, Franco ; Gulino, Alberto ; Ayrault, Olivier ; Fruci, Doriana ; Di Marcotullio, Lucia
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3304-15, Article 3304
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β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells
Author / Creator:Miele, Evelina ; Po, Agnese ; Begalli, Federica ; Antonucci, Laura ; Mastronuzzi, Angela ; Marras, Carlo Efisio ; Carai, Andrea ; Cucchi, Danilo ; Abballe, Luana ; Besharat, Zein Mersini ; Catanzaro, Giuseppina ; Infante, Paola ; Di Marcotullio, Lucia ; Canettieri, Gianluca ; De Smaele, Enrico ; Screpanti, Isabella ; Locatelli, Franco ; Ferretti, Elisabetta
Publisher:England: BioMed Central
Journal title:BMC cancer, 2017-07, Vol.17 (1), p.488-488, Article 488
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Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Author / Creator:Coni, Sonia ; Mancuso, Anna Barbara ; Di Magno, Laura ; Sdruscia, Giulia ; Manni, Simona ; Serrao, Silvia Maria ; Rotili, Dante ; Spiombi, Eleonora ; Bufalieri, Francesca ; Petroni, Marialaura ; Kusio-Kobialka, Monika ; De Smaele, Enrico ; Ferretti, Elisabetta ; Capalbo, Carlo ; Mai, Antonello ; Niewiadomski, Pawel ; Screpanti, Isabella ; Di Marcotullio, Lucia ; Canettieri, Gianluca
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.44079-44079, Article 44079
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Foxm1 controls a pro-stemness microRNA network in neural stem cells
Author / Creator:Besharat, Zein Mersini ; Abballe, Luana ; Cicconardi, Francesco ; Bhutkar, Arjun ; Grassi, Luigi ; Le Pera, Loredana ; Moretti, Marta ; Chinappi, Mauro ; D’Andrea, Daniel ; Mastronuzzi, Angela ; Ianari, Alessandra ; Vacca, Alessandra ; De Smaele, Enrico ; Locatelli, Franco ; Po, Agnese ; Miele, Evelina ; Ferretti, Elisabetta
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.3523-14, Article 3523
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Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy
Author / Creator:Coni, Sonia ; Antonucci, Laura ; D'Amico, Davide ; Di Magno, Laura ; Infante, Paola ; De Smaele, Enrico ; Giannini, Giuseppe ; Di Marcotullio, Lucia ; Screpanti, Isabella ; Gulino, Alberto ; Canettieri, Gianluca
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-06, Vol.8 (6), p.e65718-e65718
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Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitro and in vivo
Author / Creator:Bei, Roberto ; Benvenuto, Monica ; Focaccetti, Chiara ; Fazi, Sara ; Moretti, Marta ; Nardozi, Daniela ; Angiolini, Valentina ; Ciuffa, Sara ; Cifaldi, Loredana ; Carrano, Raffaele ; Palumbo, Camilla ; Miele, Martino Tony ; Bei, Riccardo ; Barillari, Giovanni ; Manzari, Vittorio ; De Smaele, Enrico ; Modesti, Andrea ; Masuelli, Laura
Publisher:London: BioMed Central Ltd
Journal title:Journal of translational medicine, 2022-06, Vol.20 (1), p.1-286, Article 286
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Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth
Author / Creator:Miele, Evelina ; Po, Agnese ; Mastronuzzi, Angela ; Carai, Andrea ; Besharat, Zein Mersini ; Pediconi, Natalia ; Abballe, Luana ; Catanzaro, Giuseppina ; Sabato, Claudia ; De Smaele, Enrico ; Canettieri, Gianluca ; Di Marcotullio, Lucia ; Vacca, Alessandra ; Mai, Antonello ; Levrero, Massimo ; Pfister, Stefan M. ; Kool, Marcel ; Giangaspero, Felice ; Locatelli, Franco ; Ferretti, Elisabetta
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2021-02, Vol.15 (2), p.523-542
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From single gene analysis to single cell profiling: a new era for precision medicine
Author / Creator:Di Martino, Maria Teresa ; Meschini, Stefania ; Scotlandi, Katia ; Riganti, Chiara ; De Smaele, Enrico ; Zazzeroni, Francesca ; Donadelli, Massimo ; Leonetti, Carlo ; Caraglia, Michele
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2020-03, Vol.39 (1), p.48-48, Article 48
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SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation
Author / Creator:Bordin, Fabio ; Terriaca, Gloria ; Apostolico, Adriano ; Di Fiore, Annamaria ; Mir, Faranak Taj ; Bellardinelli, Sara ; Bufalieri, Francesca ; Bordone, Rosa ; Bellardinilli, Francesca ; Giannini, Giuseppe ; Canettieri, Gianluca ; Di Marcotullio, Lucia ; Ferretti, Elisabetta ; Moretti, Marta ; De Smaele, Enrico
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2024-12, Vol.10 (1), p.498-12, Article 498
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Gadd45β mediates the NF-κB suppression of JNK signalling by targeting MKK7/JNKK2
Author / Creator:Papa, Salvatore ; Zazzeroni, Francesca ; Bubici, Concetta ; Jayawardena, Shanthi ; Alvarez, Kellean ; Matsuda, Shuji ; Nguyen, Dung U. ; Pham, Can G. ; Nelsbach, Andreas H. ; Melis, Tiziana ; Smaele, Enrico De ; Tang, Wei-Jen ; D'Adamio, Luciano ; Franzoso, Guido
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2004-02, Vol.6 (2), p.146-153
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Microbiological Profiles of Dental Implants in Metabolic Syndrome Patients: A Case-Control Study
Author / Creator:Di Murro, Bianca ; Moretti, Marta ; De Smaele, Enrico ; Letizia, Claudio ; Lubrano, Carla ; Passarelli, Pier Carmine ; D’Addona, Antonio ; Pompa, Giorgio ; Papi, Piero
Publisher:Switzerland: MDPI AG
Journal title:Antibiotics (Basel), 2021-04, Vol.10 (4), p.452
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RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
Author / Creator:Di Marcotullio, Lucia ; Ferretti, Elisabetta ; De Smaele, Enrico ; Argenti, Beatrice ; Mincione, Claudia ; Zazzeroni, Francesca ; Gallo, Rita ; Masuelli, Laura ; Napolitano, Maddalena ; Maroder, Marella ; Modesti, Andrea ; Giangaspero, Felice ; Screpanti, Isabella ; Alesse, Edoardo ; Gulino, Alberto
Publisher:Washington: National Acad Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (29), p.10833-10838
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Showing 1 to 20 of 56 results

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Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation

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Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons

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Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes

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The emerging role of the KCTD proteins in cancer

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Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance

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Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells

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SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment

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Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis

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ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

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β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells

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Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma

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Foxm1 controls a pro-stemness microRNA network in neural stem cells

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Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy

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Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitro and in vivo

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Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth

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From single gene analysis to single cell profiling: a new era for precision medicine

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SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation

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Gadd45β mediates the NF-κB suppression of JNK signalling by targeting MKK7/JNKK2

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Microbiological Profiles of Dental Implants in Metabolic Syndrome Patients: A Case-Control Study

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RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

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