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ArticlesPeer ReviewedFull Text
Deep learning enables rapid identification of potent DDR1 kinase inhibitors
Author / Creator:Zhavoronkov, Alex ; Ivanenkov, Yan A. ; Aliper, Alex ; Veselov, Mark S. ; Aladinskiy, Vladimir A. ; Aladinskaya, Anastasiya V. ; Terentiev, Victor A. ; Polykovskiy, Daniil A. ; Kuznetsov, Maksim D. ; Asadulaev, Arip ; Volkov, Yury ; Zholus, Artem ; Shayakhmetov, Rim R. ; Zhebrak, Alexander ; Minaeva, Lidiya I. ; Zagribelnyy, Bogdan A. ; Lee, Lennart H. ; Soll, Richard ; Madge, David ; Xing, Li ; Guo, Tao ; Aspuru-Guzik, Alán
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2019-09, Vol.37 (9), p.1038-1040
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Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion
Author / Creator:Sun, Xiujie ; Wu, Bogang ; Chiang, Huai-Chin ; Deng, Hui ; Zhang, Xiaowen ; Xiong, Wei ; Liu, Junquan ; Rozeboom, Aaron M. ; Harris, Brent T. ; Blommaert, Eline ; Gomez, Antonio ; Garcia, Roderic Espin ; Zhou, Yufan ; Mitra, Payal ; Prevost, Madeleine ; Zhang, Deyi ; Banik, Debarati ; Isaacs, Claudine ; Berry, Deborah ; Lai, Catherine ; Chaldekas, Krysta ; Latham, Patricia S. ; Brantner, Christine A. ; Popratiloff, Anastas ; Jin, Victor X. ; Zhang, Ningyan ; Hu, Yanfen ; Pujana, Miguel Angel ; Curiel, Tyler J. ; An, Zhiqiang ; Li, Rong
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-11, Vol.599 (7886), p.673-678
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Identification of DDR1 Inhibitors from Marine Compound Library Based on Pharmacophore Model and Scaffold Hopping
Author / Creator:Hu, Honghui ; Tao, Jiahua ; Luo, Lianxiang
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-01, Vol.26 (3), p.1099
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Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations
Author / Creator:Shariati, Maryam ; Evans, Kurt W. ; Zheng, Xiaofeng ; Bristow, Christopher A. ; Ng, Patrick Kwok-Shing ; Rizvi, Yasmeen Q. ; Tapia, Coya ; Yang, Fei ; Carugo, Alessandro ; Heffernan, Timothy P. ; Peoples, Michael D. ; Tripathy, Debu ; Meric-Bernstam, Funda
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-07, Vol.40 (26), p.4425-4439
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DDR1 promotes breast tumor growth by suppressing antitumor immunity
Author / Creator:Zhong, Xing ; Zhang, Weiwei ; Sun, Tianhao
Publisher:Greece: Spandidos Publications
Journal title:Oncology reports, 2019-12, Vol.42 (6), p.2844-2854
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Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy
Author / Creator:Chou, Hsin-Chaio ; Chen, Chung-Hwan ; Chou, Liang-Yin ; Cheng, Tsung-Lin ; Kang, Lin ; Chuang, Shu-Chun ; Lin, Yi-Shan ; Ho, Mei-Ling ; Wang, Yan-Hsiung ; Lin, Sung-Yen ; Wang, Chau-Zen
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-10, Vol.21 (19), p.6991
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Targeting of DDR1 with antibody‐drug conjugates has antitumor effects in a mouse model of colon carcinoma
Author / Creator:Tao, Yiran ; Wang, Ruixue ; Lai, Qinhuai ; Wu, Mengdan ; Wang, Yuxi ; Jiang, Xiaohua ; Zeng, Lishi ; Zhou, Shijie ; Li, Zhongping ; Yang, Tinghan ; Yao, Yuqin ; Wu, Yangping ; Yu, Lin ; Fu, Yuyin ; Lai, Weirong ; Peng, Yujia ; Lu, Ying ; Zhang, Zhixiong ; Guo, Cuiyu ; Zhang, Guangbing ; Gou, Lantu ; Yang, Jinliang
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2019-09, Vol.13 (9), p.1855-1873
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Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation
Author / Creator:Denny, William A ; Flanagan, Jack U
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2021-11, Vol.11 (11), p.1671
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Targeting Discoidin Domain Receptor 1 (DDR1) Signaling and Its Crosstalk with β 1 -integrin Emerges as a Key Factor for Breast Cancer Chemosensitization upon Collagen Type 1 Binding
Author / Creator:Baltes, Fabian ; Caspers, Julia ; Henze, Svenja ; Schlesinger, Martin ; Bendas, Gerd
Publisher:Switzerland
Journal title:International journal of molecular sciences, 2020-07, Vol.21 (14)
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Deep learning enables rapid identification of potent DDR1 kinase inhibitors

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Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion

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Identification of DDR1 Inhibitors from Marine Compound Library Based on Pharmacophore Model and Scaffold Hopping

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Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations

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DDR1 promotes breast tumor growth by suppressing antitumor immunity

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Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy

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Targeting of DDR1 with antibody‐drug conjugates has antitumor effects in a mouse model of colon carcinoma

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Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation

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Targeting Discoidin Domain Receptor 1 (DDR1) Signaling and Its Crosstalk with β 1 -integrin Emerges as a Key Factor for Breast Cancer Chemosensitization upon Collagen Type 1 Binding

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