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ArticlesPeer ReviewedFull Text
The p53-caspase-2 axis in the cell cycle and DNA damage response
Author / Creator:Lim, Yoon ; Dorstyn Loretta ; Kumar, Sharad
Publisher:Seoul: Springer Nature B.V
Journal title:Experimental & molecular medicine, 2021-04, Vol.53 (4), p.517-527
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ArticlesPeer ReviewedFull Text
Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
Author / Creator:Lim, Yoon ; De Bellis Dylan ; Sandow, Jarrod J ; Capalbo Luisa ; D’Avino Pier Paolo ; Murphy, James M ; Webb, Andrew I ; Dorstyn Loretta ; Kumar, Sharad
Publisher:Rome: Nature Publishing Group
Journal title:Cell death and differentiation, 2021-01, Vol.28 (1), p.349-366
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ArticlesPeer ReviewedFull Text
The 9th Barossa Meeting: Cell Signalling in Cancer Medicine
Author / Creator:Dorstyn Loretta ; Tvorogov Denis ; Malek Shiva ; Robinson, Nirmal
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2020-03, Vol.11 (3)
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ArticlesPeer ReviewedFull Text
Understanding Developmental Cell Death Using Drosophila as a Model System
Author / Creator:Umargamwala, Ruchi ; Manning, Jantina ; Dorstyn, Loretta ; Denton, Donna ; Kumar, Sharad
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-02, Vol.13 (4), p.347
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ArticlesPeer ReviewedFull Text
tumor suppressor function for caspase-2
Author / Creator:Ho, Lien Ha ; Taylor, Robyn ; Dorstyn, Loretta ; Cakouros, Dimitrios ; Bouillet, Philippe ; Kumar, Sharad
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (13), p.5336-5341
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ArticlesPeer ReviewedFull Text
Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice
Author / Creator:Puccini, Joseph ; Shalini, Sonia ; Voss, Anne K. ; Gatei, Magtouf ; Wilson, Claire H. ; Hiwase, Devendra K. ; Lavin, Martin F. ; Dorstyn, Loretta ; Kumar, Sharad
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (49), p.19920-19925
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ArticlesPeer ReviewedFull Text
Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling
Author / Creator:Dorstyn Loretta ; Hackett-Jones, Emily ; Nikolic Andrej ; Norris, Murray D ; Lim, Yoon ; Toubia, John ; Haber, Michelle ; Kumar, Sharad
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2019-01, Vol.10 (2)
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ArticlesPeer ReviewedFull Text
Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice
Author / Creator:Dawar, Swati ; Shahrin, Nur Hezrin ; Sladojevic, Nikolina ; D'Andrea, Richard J ; Dorstyn, Loretta ; Hiwase, Devendra K ; Kumar, Sharad
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2016-12, Vol.7 (12), p.e2509-e2509
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ArticlesPeer ReviewedFull Text
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons
Author / Creator:Howitt, Jason ; Putz, Ulrich ; Lackovic, Jenny ; Doan, Anh ; Dorstyn, Loretta ; Cheng, Hong ; Yang, Baoli ; Chan-Ling, Tailoi ; Silke, John ; Kumar, Sharad ; Tan, Seong-Seng
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (36), p.15489-15494
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ArticlesPeer ReviewedFull Text
DRONC, an ecdysone-inducible Drosophila caspase
Author / Creator:Dorstyn, L ; Colussi, P.A ; Quinn, L.M ; Richardson, H ; Kumar, S
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-04, Vol.96 (8), p.4307-4312
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ArticlesPeer ReviewedFull Text
New insights into apoptosome structure and function
Author / Creator:Dorstyn, Loretta ; Akey, Christopher W ; Kumar, Sharad
Publisher:Rome: Nature Publishing Group
Journal title:Cell death and differentiation, 2018-07, Vol.25 (7), p.1194-1208
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ArticlesPeer ReviewedFull Text
p53 accumulation following cytokinesis failure in the absence of caspase-2
Author / Creator:Lim, Yoon ; De Bellis, Dylan ; Dorstyn, Loretta ; Kumar, Sharad
Publisher:Rome: Nature Publishing Group
Journal title:Cell death and differentiation, 2018-11, Vol.25 (11), p.2050-2052
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ArticlesPeer ReviewedFull Text
Understanding Developmental Cell Death Using IDrosophila/I as a Model System
Author / Creator:Umargamwala, Ruchi ; Manning, Jantina ; Dorstyn, Loretta ; Denton, Donna ; Kumar, Sharad
Publisher:MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-02, Vol.13 (4)
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ArticlesPeer ReviewedFull Text
Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity
Author / Creator:Wilson, Claire H ; Nikolic, Andrej ; Kentish, Stephen J ; Keller, Marianne ; Hatzinikolas, George ; Dorstyn, Loretta ; Page, Amanda J ; Kumar, Sharad
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2017-10, Vol.8 (10), p.e3136-e3136
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ArticlesPeer ReviewedFull Text
Divalent Metal Transporter 1 (DMT1) Regulation by Ndfip 1 Prevents Metal Toxicity in Human Neurons
Author / Creator:Howitt, Jason ; Putz, Ulrich ; Lackovic, Jenny ; Doan, Anh ; Dorstyn, Loretta ; Cheng, Hong ; Yang, Baoli ; Chan-Ling, Tailoi ; Silke, John ; Kumar, Sharad ; Tan, Seong-Seng ; Rouault, Tracey A.
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (36), p.15489-15494
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ArticlesFull Text
Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
Author / Creator:Kumar, Sharad ; Lim, Yoon ; De Bellis, Dylan ; Sandow, Jarrod J ; Capalbo, Luisa ; D'avino, Pier Paolo ; Murphy, James M ; Webb, Andrew I ; Dorstyn, Loretta
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-03
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The p53-caspase-2 axis in the cell cycle and DNA damage response

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Phosphorylation by Aurora B kinase regulates caspase-2 activity and function

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The 9th Barossa Meeting: Cell Signalling in Cancer Medicine

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Understanding Developmental Cell Death Using Drosophila as a Model System

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tumor suppressor function for caspase-2

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Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice

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Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling

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Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice

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Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons

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DRONC, an ecdysone-inducible Drosophila caspase

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New insights into apoptosome structure and function

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p53 accumulation following cytokinesis failure in the absence of caspase-2

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Understanding Developmental Cell Death Using IDrosophila/I as a Model System

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Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity

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Divalent Metal Transporter 1 (DMT1) Regulation by Ndfip 1 Prevents Metal Toxicity in Human Neurons

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Phosphorylation by Aurora B kinase regulates caspase-2 activity and function

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