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204 results for Dowsett,+Mitch

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ArticlesPeer ReviewedFull Text
20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years
Author / Creator:Pan, Hongchao ; Gray, Richard ; Braybrooke, Jeremy ; Davies, Christina ; Taylor, Carolyn ; McGale, Paul ; Peto, Richard ; Pritchard, Kathleen I ; Bergh, Jonas ; Dowsett, Mitch ; Hayes, Daniel F
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-11, Vol.377 (19), p.1836-1846
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ArticlesPeer ReviewedFull Text
Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer
Author / Creator:Chopra, Neha ; Tovey, Holly ; Pearson, Alex ; Cutts, Ros ; Toms, Christy ; Proszek, Paula ; Hubank, Michael ; Dowsett, Mitch ; Dodson, Andrew ; Daley, Frances ; Kriplani, Divya ; Gevensleben, Heidi ; Davies, Helen Ruth ; Degasperi, Andrea ; Roylance, Rebecca ; Chan, Stephen ; Tutt, Andrew ; Skene, Anthony ; Evans, Abigail ; Bliss, Judith M. ; Nik-Zainal, Serena ; Turner, Nicholas C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2662-2662, Article 2662
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ArticlesPeer ReviewedFull Text
11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial
Author / Creator:Cameron, David, Prof ; Piccart-Gebhart, Martine J, PhD ; Gelber, Richard D, PhD ; Procter, Marion, PhD ; Goldhirsch, Aron, MD ; de Azambuja, Evandro, MD ; Castro, Gilberto, MD ; Untch, Michael, MD ; Smith, Ian, MD ; Gianni, Luca, MD ; Baselga, Jose, MD ; Al-Sakaff, Nedal, PhD ; Lauer, Sabine, PhD ; McFadden, Eleanor, MA ; Leyland-Jones, Brian, MBBS ; Bell, Richard, MBBS ; Dowsett, Mitch, PhD ; Jackisch, Christian, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-03, Vol.389 (10075), p.1195-1205
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ArticlesPeer ReviewedFull Text
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial
Author / Creator:Cuzick, Jack, Prof ; Sestak, Ivana, PhD ; Baum, Michael, Prof ; Buzdar, Aman, Prof ; Howell, Anthony, Prof ; Dowsett, Mitch, Prof ; Forbes, John F, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2010-12, Vol.11 (12), p.1135-1141
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ArticlesPeer ReviewedFull Text
Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer (POETIC): an open-label, multicentre, parallel-g...
Author / Creator:Smith, Ian, Prof ; Robertson, John, Prof ; Kilburn, Lucy, MSc ; Wilcox, Maggie ; Evans, Abigail, FRCS ; Holcombe, Chris, Prof ; Horgan, Kieran, Prof ; Kirwan, Cliona, Prof ; Mallon, Elizabeth, MBChB ; Sibbering, Mark, FRCS ; Skene, Anthony, FRCS ; Vidya, Raghavan, FRCS ; Cheang, Maggie, PhD ; Banerji, Jane, BSc ; Morden, James, MSc ; Sidhu, Kally, BSc ; Dodson, Andrew, MPhil ; Bliss, Judith M, Prof ; Dowsett, Mitch, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-11, Vol.21 (11), p.1443-1454
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ArticlesPeer ReviewedFull Text
Clinical validity of clinical treatment score 5 (CTS5) for estimating risk of late recurrence in unselected, non-trial patients with early oestrogen receptor-positive breast cancer
Author / Creator:Richman, Juliet ; Ring, Alistair ; Dowsett, Mitch ; Sestak, Ivana
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2021-02, Vol.186 (1), p.115-123
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Newsletter articlesFull Text
Breast Cancer; Estrogen-suppressing drugs substantially reduce breast cancer deaths
Publisher:Atlanta: NewsRx
Journal title:Biotech Business Week, 2015, p.48
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ArticlesPeer ReviewedFull Text
Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer
Author / Creator:Abubakar, Mustapha ; Figueroa, Jonine ; Ali, H. Raza ; Blows, Fiona ; Lissowska, Jolanta ; Caldas, Carlos ; Easton, Douglas F. ; Sherman, Mark E. ; Garcia-Closas, Montserrat ; Dowsett, Mitch ; Pharoah, Paul D.
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2019-09, Vol.32 (9), p.1244-1256
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ArticlesPeer ReviewedFull Text
Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial
Author / Creator:Cuzick, Jack, Prof ; Sestak, Ivana, PhD ; Forbes, John F, Prof ; Dowsett, Mitch, Prof ; Knox, Jill, MSc ; Cawthorn, Simon, MD ; Saunders, Christobel, Prof ; Roche, Nicola, MD ; Mansel, Robert E, Prof ; von Minckwitz, Gunter, MD ; Bonanni, Bernardo, MD ; Palva, Tiina, MD ; Howell, Anthony, Prof
Publisher:Kidlington: Elsevier
Journal title:The Lancet (British edition), 2014-03, Vol.383 (9922), p.1041-1048
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ArticlesPeer ReviewedFull Text
HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity
Author / Creator:Hanna, Wedad M ; Rüschoff, Josef ; Bilous, Michael ; Coudry, Renata A ; Dowsett, Mitch ; Osamura, Robert Y ; Penault-Llorca, Frédérique ; van de Vijver, Marc ; Viale, Giuseppe
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2014-01, Vol.27 (1), p.4-18
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ArticlesPeer ReviewedFull Text
Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities
Author / Creator:Pancholi, Sunil ; Ribas, Ricardo ; Simigdala, Nikiana ; Schuster, Eugene ; Nikitorowicz-Buniak, Joanna ; Ressa, Anna ; Gao, Qiong ; Leal, Mariana Ferreira ; Bhamra, Amandeep ; Thornhill, Allan ; Morisset, Ludivine ; Montaudon, Elodie ; Sourd, Laura ; Fitzpatrick, Martin ; Altelaar, Maarten ; Johnston, Stephen R. ; Marangoni, Elisabetta ; Dowsett, Mitch ; Martin, Lesley-Ann
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-06, Vol.39 (25), p.4781-4797
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ArticlesPeer ReviewedFull Text
Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in...
Author / Creator:Sgroi, Dennis C, Prof ; Sestak, Ivana, PhD ; Cuzick, Jack, Prof ; Zhang, Yi, PhD ; Schnabel, Catherine A, PhD ; Schroeder, Brock, PhD ; Erlander, Mark G, PhD ; Dunbier, Anita, PhD ; Sidhu, Kally, BSc ; Lopez-Knowles, Elena, PhD ; Goss, Paul E, Prof ; Dowsett, Mitch, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-10, Vol.14 (11), p.1067-1076
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ArticlesPeer ReviewedFull Text
Digital mammographic density and breast cancer risk: a case-control study of six alternative density assessment methods
Author / Creator:Eng, Amanda ; Gallant, Zoe ; Shepherd, John ; McCormack, Valerie ; Li, Jingmei ; Dowsett, Mitch ; Vinnicombe, Sarah ; Allen, Steve ; dos-Santos-Silva, Isabel
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2014-09, Vol.16 (5), p.439-439, Article 439
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ArticlesPeer ReviewedFull Text
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update
Author / Creator:Wolff, Antonio C ; Hammond, M Elizabeth H ; Hicks, David G ; Dowsett, Mitch ; McShane, Lisa M ; Allison, Kimberly H ; Allred, Donald C ; Bartlett, John M S ; Bilous, Michael ; Fitzgibbons, Patrick ; Hanna, Wedad ; Jenkins, Robert B ; Mangu, Pamela B ; Paik, Soonmyung ; Perez, Edith A ; Press, Michael F ; Spears, Patricia A ; Vance, Gail H ; Viale, Giuseppe ; Hayes, Daniel F
Publisher:United States: College of American Pathologists
Journal title:Archives of pathology & laboratory medicine (1976), 2014-02, Vol.138 (2), p.241-256
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ArticlesPeer ReviewedFull Text
Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data
Author / Creator:Cuzick, Jack, Prof ; Sestak, Ivana, PhD ; Bonanni, Bernardo, MD ; Costantino, Joseph P, DrPH ; Cummings, Steve, MD ; DeCensi, Andrea, Prof ; Dowsett, Mitch, Prof ; Forbes, John F, Prof ; Ford, Leslie, MD ; LaCroix, Andrea Z, Prof ; Mershon, John, MD ; Mitlak, Bruce H, MD ; Powles, Trevor, Prof ; Veronesi, Umberto, Prof ; Vogel, Victor, Prof ; Wickerham, D Lawrence, MD
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2013-05, Vol.381 (9880), p.1827-1834
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ArticlesPeer ReviewedFull Text
Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer
Author / Creator:Simigdala, Nikiana ; Gao, Qiong ; Pancholi, Sunil ; Roberg-Larsen, Hanne ; Zvelebil, Marketa ; Ribas, Ricardo ; Folkerd, Elizabeth ; Thompson, Andrew ; Bhamra, Amandeep ; Dowsett, Mitch ; Martin, Lesley-Ann
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2016-06, Vol.18 (1), p.58-58, Article 58
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ArticlesPeer ReviewedFull Text
2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial
Author / Creator:Goldhirsch, Aron, Prof ; Gelber, Richard D, Prof ; Piccart-Gebhart, Martine J, Prof ; de Azambuja, Evandro, MD ; Procter, Marion, MSci ; Suter, Thomas M, Prof ; Jackisch, Christian, Prof ; Cameron, David, Prof ; Weber, Harald A, MD ; Heinzmann, Dominik, PhD ; Lago, Lissandra Dal, MD ; McFadden, Eleanor, MA ; Dowsett, Mitch, Prof ; Untch, Michael, Prof ; Gianni, Luca, MD ; Bell, Richard, Prof ; Köhne, Claus-Henning, Prof ; Vindevoghel, Anita, MD ; Andersson, Michael, MD ; Brunt, A Murray, MD ; Otero-Reyes, Douglas, MD ; Song, Santai, MD ; Smith, Ian, Prof ; Leyland-Jones, Brian, PhD ; Baselga, Jose, Prof
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2013-09, Vol.382 (9897), p.1021-1028
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ArticlesPeer ReviewedFull Text
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
Author / Creator:Weigelt, Britta, PhD ; Mackay, Alan, BSc ; A'hern, Roger, MSc ; Natrajan, Rachael, PhD ; Tan, David SP, MD ; Dowsett, Mitch, Prof ; Ashworth, Alan, Prof ; Reis-Filho, Jorge S, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2010-04, Vol.11 (4), p.339-349
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ArticlesPeer ReviewedFull Text
Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance
Author / Creator:Martin, Lesley-Ann ; Ribas, Ricardo ; Simigdala, Nikiana ; Schuster, Eugene ; Pancholi, Sunil ; Tenev, Tencho ; Gellert, Pascal ; Buluwela, Laki ; Harrod, Alison ; Thornhill, Allan ; Nikitorowicz-Buniak, Joanna ; Bhamra, Amandeep ; Turgeon, Marc-Olivier ; Poulogiannis, George ; Gao, Qiong ; Martins, Vera ; Hills, Margaret ; Garcia-Murillas, Isaac ; Fribbens, Charlotte ; Patani, Neill ; Li, Zheqi ; Sikora, Matthew J. ; Turner, Nicholas ; Zwart, Wilbert ; Oesterreich, Steffi ; Carroll, Jason ; Ali, Simak ; Dowsett, Mitch
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1865-15, Article 1865
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ArticlesPeer ReviewedFull Text
Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treat...
Author / Creator:Bianchini, Giampaolo ; Kiermaier, Astrid ; Bianchi, Giulia Valeria ; Im, Young-Hyuck ; Pienkowski, Tadeusz ; Liu, Mei-Ching ; Tseng, Ling-Ming ; Dowsett, Mitch ; Zabaglo, Lila ; Kirk, Sarah ; Szado, Tania ; Eng-Wong, Jennifer ; Amler, Lukas C ; Valagussa, Pinuccia ; Gianni, Luca
Publisher:England: BioMed Central
Journal title:Breast cancer research : BCR, 2017-02, Vol.19 (1), p.16-16, Article 16
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20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

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Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer

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11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial

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Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial

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Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer (POETIC): an open-label, multicentre, parallel-g...

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Clinical validity of clinical treatment score 5 (CTS5) for estimating risk of late recurrence in unselected, non-trial patients with early oestrogen receptor-positive breast cancer

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Breast Cancer; Estrogen-suppressing drugs substantially reduce breast cancer deaths

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Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer

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Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial

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HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity

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Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

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Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in...

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Digital mammographic density and breast cancer risk: a case-control study of six alternative density assessment methods

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Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update

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Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data

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Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer

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2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial

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Breast cancer molecular profiling with single sample predictors: a retrospective analysis

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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

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Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treat...

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