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ArticlesPeer ReviewedFull Text
Ischemia and reperfusion—from mechanism to translation
Author / Creator:Eltzschig, Holger K ; Eckle, Tobias
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2011-11, Vol.17 (11), p.1391-1401
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ArticlesPeer ReviewedFull Text
Hypoxia signaling in human diseases and therapeutic targets
Author / Creator:Lee, Jae W. ; Ko, Junsuk ; Ju, Cynthia ; Eltzschig, Holger K.
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2019, 51(0), , pp.1-13
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ArticlesPeer ReviewedFull Text
Hypoxia and inflammation are two sides of the same coin
Author / Creator:Bartels, Karsten ; Grenz, Almut ; Eltzschig, Holger K.
Publisher:United States: NATIONAL ACADEMY OF SCIENCES
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (46), p.18351-18352
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ArticlesPeer ReviewedFull Text
Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain
Author / Creator:Zhu, Shouan ; Zhu, Jianxi ; Zhen, Gehua ; Hu, Yihe ; An, Senbo ; Li, Yusheng ; Zheng, Qin ; Chen, Zhiyong ; Yang, Ya ; Wan, Mei ; Skolasky, Richard Leroy ; Cao, Yong ; Wu, Tianding ; Gao, Bo ; Yang, Mi ; Gao, Manman ; Kuliwaba, Julia ; Ni, Shuangfei ; Wang, Lei ; Wu, Chuanlong ; Findlay, David ; Eltzschig, Holger K. ; Ouyang, Hong Wei ; Crane, Janet ; Zhou, Feng-Quan ; Guan, Yun ; Dong, Xinzhong ; Cao, Xu
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-03, Vol.129 (3), p.1076-1093
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ArticlesPeer ReviewedFull Text
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine
Author / Creator:Niemann, Birte ; Haufs-Brusberg, Saskia ; Puetz, Laura ; Feickert, Martin ; Jaeckstein, Michelle Y. ; Hoffmann, Anne ; Zurkovic, Jelena ; Heine, Markus ; Trautmann, Eva-Maria ; Müller, Christa E. ; Tönjes, Anke ; Schlein, Christian ; Jafari, Azin ; Eltzschig, Holger K. ; Gnad, Thorsten ; Blüher, Matthias ; Krahmer, Natalie ; Kovacs, Peter ; Heeren, Joerg ; Pfeifer, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-09, Vol.609 (7926), p.361-368
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ArticlesPeer ReviewedFull Text
Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury
Author / Creator:Koeppen, Michael ; Lee, Jae W. ; Seo, Seong-Wook ; Brodsky, Kelley S. ; Kreth, Simone ; Yang, Ivana V. ; Buttrick, Peter M. ; Eckle, Tobias ; Eltzschig, Holger K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-02, Vol.9 (1), p.816-13, Article 816
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ArticlesPeer ReviewedFull Text
Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells
Author / Creator:Hadi, Tarik ; Boytard, Ludovic ; Silvestro, Michele ; Alebrahim, Dornazsadat ; Jacob, Samson ; Feinstein, Jordyn ; Barone, Krista ; Spiro, Wes ; Hutchison, Susan ; Simon, Russell ; Rateri, Debra ; Pinet, Florence ; Fenyo, David ; Adelman, Mark ; Moore, Kathryn J. ; Eltzschig, Holger K. ; Daugherty, Alan ; Ramkhelawon, Bhama
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-11, Vol.9 (1), p.5022-16, Article 5022
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ArticlesPeer ReviewedFull Text
HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium
Author / Creator:Eckle, Tobias ; Brodsky, Kelley ; Bonney, Megan ; Packard, Thomas ; Han, Jun ; Borchers, Christoph H. ; Mariani, Thomas J. ; Kominsky, Douglas J. ; Mittelbronn, Michel ; Eltzschig, Holger K.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2013-09, Vol.11 (9), p.e1001665-e1001665
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ArticlesPeer ReviewedFull Text
Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
Author / Creator:Clambey, Eric T ; McNamee, Eóin N ; Westrich, Joseph A ; Glover, Louise E ; Campbell, Eric L ; Jedlicka, Paul ; de Zoeten, Edwin F ; Cambier, John C ; Stenmark, Kurt R ; Colgan, Sean P ; Eltzschig, Holger K
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.E2784-E2793
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ArticlesPeer ReviewedFull Text
MicroRNAs in mucosal inflammation
Author / Creator:Neudecker, Viola ; Yuan, Xiaoyi ; Bowser, Jessica L. ; Eltzschig, Holger K.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of molecular medicine (Berlin, Germany), 2017-09, Vol.95 (9), p.935-949
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ArticlesPeer ReviewedFull Text
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity
Author / Creator:Evans, Christopher M. ; Raclawska, Dorota S. ; Ttofali, Fani ; Liptzin, Deborah R. ; Fletcher, Ashley A. ; Harper, Daniel N. ; McGing, Maggie A. ; McElwee, Melissa M. ; Williams, Olatunji W. ; Sanchez, Elizabeth ; Roy, Michelle G. ; Kindrachuk, Kristen N. ; Wynn, Thomas A. ; Eltzschig, Holger K. ; Blackburn, Michael R. ; Tuvim, Michael J. ; Janssen, William J. ; Schwartz, David A. ; Dickey, Burton F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-02, Vol.6 (1), p.6281-6281, Article 6281
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ArticlesPeer ReviewedFull Text
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia
Author / Creator:Eckle, Tobias ; Hartmann, Katherine ; Bonney, Stephanie ; Reithel, Susan ; Mittelbronn, Michel ; Walker, Lori A ; Lowes, Brian D ; Han, Jun ; Borchers, Christoph H ; Buttrick, Peter M ; Kominsky, Douglas J ; Colgan, Sean P ; Eltzschig, Holger K
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2012-05, Vol.18 (5), p.774-782
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ArticlesPeer ReviewedFull Text
Impact of perioperative organ injury on morbidity and mortality in 28 million surgical patients
Author / Creator:Kork, Felix ; Liang, Yafen ; Ginde, Adit A. ; Yuan, Xiaoyi ; Rossaint, Rolf ; Liu, Hongfang ; Evers, Alex S. ; Eltzschig, Holger K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-04, Vol.16 (1), p.3366-9, Article 3366
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ArticlesPeer ReviewedFull Text
Assessment of a multimodal analgesia protocol to allow the implementation of enhanced recovery after cardiac surgery: Retrospective analysis of patient outcomes
Author / Creator:Markham, Travis, MD ; Wegner, Robert, MD ; Hernandez, Nadia, MD ; Lee, Jae W., MD ; Choi, Warren, MD ; Eltzschig, Holger K., MD, PhD ; Zaki, John, MD
Publisher:United States: Elsevier Inc
Journal title:Journal of clinical anesthesia, 2019-05, Vol.54, p.76-80
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ArticlesPeer ReviewedFull Text
Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease
Author / Creator:Poth, Jens M. ; Brodsky, Kelley ; Ehrentraut, Heidi ; Grenz, Almut ; Eltzschig, Holger K.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Journal of molecular medicine (Berlin, Germany), 2013-02, Vol.91 (2), p.183-193
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ArticlesPeer ReviewedFull Text
Selective Deletion of the A1 Adenosine Receptor Abolishes Heart-Rate Slowing Effects of Intravascular Adenosine In Vivo
Author / Creator:Koeppen, Michael ; Eckle, Tobias ; Eltzschig, Holger K.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-08, Vol.4 (8), p.e6784-e6784
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ArticlesPeer ReviewedFull Text
Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent
Author / Creator:Song, Anren ; Zhang, Yujin ; Han, Leng ; Yegutkin, Gennady G. ; Liu, Hong ; Sun, Kaiqi ; D’Alessandro, Angelo ; Li, Jessica ; Karmouty-Quintana, Harry ; Iriyama, Takayuki ; Weng, Tingting ; Zhao, Shushan ; Wang, Wei ; Wu, Hongyu ; Nemkov, Travis ; Subudhi, Andrew W. ; Jameson-Van Houten, Sonja ; Julian, Colleen G. ; Lovering, Andrew T. ; Hansen, Kirk C. ; Zhang, Hong ; Bogdanov, Mikhail ; Dowhan, William ; Jin, Jianping ; Kellems, Rodney E. ; Eltzschig, Holger K. ; Blackburn, Michael ; Roach, Robert C. ; Xia, Yang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.14108-14108, Article 14108
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ArticlesPeer ReviewedFull Text
HIF-2α-dependent induction of miR-29a restrains TH1 activity during T cell dependent colitis
Author / Creator:Czopik, Agnieszka K. ; McNamee, Eóin N. ; Vaughn, Victoria ; Huang, Xiangsheng ; Bang, In Hyuk ; Clark, Trent ; Wang, Yanyu ; Ruan, Wei ; Nguyen, Tom ; Masterson, Joanne C. ; Tak, Eunyoung ; Frank, Sandra ; Collins, Colm B. ; Li, Howard ; Rodriguez-Aguayo, Cristian ; Lopez-Berestein, Gabriel ; Gerich, Mark E. ; Furuta, Glenn T. ; Yuan, Xiaoyi ; Sood, Anil K. ; de Zoeten, Edwin F. ; Eltzschig, Holger K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-09, Vol.15 (1), p.8042-17, Article 8042
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ArticlesPeer ReviewedFull Text
Adora2b Adenosine Receptor Engagement Enhances Regulatory T Cell Abundance during Endotoxin-Induced Pulmonary Inflammation
Author / Creator:Ehrentraut, Heidi ; Westrich, Joseph A. ; Eltzschig, Holger K. ; Clambey, Eric T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e32416
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ArticlesPeer ReviewedFull Text
Adenosine metabolized from extracellular ATP ameliorates organ injury by triggering A2BR signaling
Author / Creator:Kelestemur, Taha ; Németh, Zoltán H. ; Pacher, Pal ; Beesley, Jennet ; Robson, Simon C. ; Eltzschig, Holger K. ; Haskó, György
Publisher:London: BioMed Central Ltd
Journal title:Respiratory research, 2023-07, Vol.24 (1), p.1-186, Article 186
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Showing 1 to 20 of 144 results

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Ischemia and reperfusion—from mechanism to translation

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Hypoxia signaling in human diseases and therapeutic targets

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Hypoxia and inflammation are two sides of the same coin

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Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain

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Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine

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Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury

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Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells

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HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium

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Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

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MicroRNAs in mucosal inflammation

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The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

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Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

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Impact of perioperative organ injury on morbidity and mortality in 28 million surgical patients

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Assessment of a multimodal analgesia protocol to allow the implementation of enhanced recovery after cardiac surgery: Retrospective analysis of patient outcomes

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Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease

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Selective Deletion of the A1 Adenosine Receptor Abolishes Heart-Rate Slowing Effects of Intravascular Adenosine In Vivo

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Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent

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HIF-2α-dependent induction of miR-29a restrains TH1 activity during T cell dependent colitis

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Adora2b Adenosine Receptor Engagement Enhances Regulatory T Cell Abundance during Endotoxin-Induced Pulmonary Inflammation

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Adenosine metabolized from extracellular ATP ameliorates organ injury by triggering A2BR signaling

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