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ArticlesPeer ReviewedFull Text
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
Author / Creator:Yachida, Shinichi ; Jones, Siân ; Bozic, Ivana ; Antal, Tibor ; Leary, Rebecca ; Fu, Baojin ; Kamiyama, Mihoko ; Hruban, Ralph H. ; Eshleman, James R. ; Nowak, Martin A. ; Velculescu, Victor E. ; Kinzler, Kenneth W. ; Vogelstein, Bert ; Iacobuzio-Donahue, Christine A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-10, Vol.467 (7319), p.1114-1117
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Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing
Author / Creator:Lokhandwala, Parvez M ; Tseng, Li-Hui ; Rodriguez, Erika ; Zheng, Gang ; Pallavajjalla, Aparna ; Gocke, Christopher D ; Eshleman, James R ; Lin, Ming-Tseh
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2019-07, Vol.19 (1), p.665-665, Article 665
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Clinical detection and categorization of uncommon and concomitant mutations involving BRAF
Author / Creator:Zheng, Gang ; Tseng, Li-Hui ; Chen, Guoli ; Haley, Lisa ; Illei, Peter ; Gocke, Christopher D ; Eshleman, James R ; Lin, Ming-Tseh
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2015-10, Vol.15 (1), p.779-779, Article 779
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The genetics of ductal adenocarcinoma of the pancreas in the year 2020: dramatic progress, but far to go
Author / Creator:Thompson, Elizabeth D. ; Roberts, Nicholas J. ; Wood, Laura D. ; Eshleman, James R. ; Goggins, Michael G. ; Kern, Scott E. ; Klein, Alison P. ; Hruban, Ralph H.
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2020-12, Vol.33 (12), p.2544-2563
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Clinical validation of KRAS, BRAF, and EGFR mutation detection using next-generation sequencing
Author / Creator:Lin, Ming-Tseh ; Mosier, Stacy L ; Thiess, Michele ; Beierl, Katie F ; Debeljak, Marija ; Tseng, Li-Hui ; Chen, Guoli ; Yegnasubramanian, Srinivasan ; Ho, Hao ; Cope, Leslie ; Wheelan, Sarah J ; Gocke, Christopher D ; Eshleman, James R
Publisher:England: Oxford University Press
Journal title:American journal of clinical pathology, 2014-06, Vol.141 (6), p.856-866
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ArticlesPeer ReviewedFull Text
Fundamentals of pyrosequencing
Author / Creator:Harrington, Colleen T ; Lin, Elaine I ; Olson, Matthew T ; Eshleman, James R
Publisher:United States: College of American Pathologists
Journal title:Archives of pathology & laboratory medicine (1976), 2013-09, Vol.137 (9), p.1296-1303
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Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas
Author / Creator:Dal Molin, Marco ; Matthaei, Hanno ; Wu, Jian ; Blackford, Amanda ; Debeljak, Marija ; Rezaee, Neda ; Wolfgang, Christopher L. ; Butturini, Giovanni ; Salvia, Roberto ; Bassi, Claudio ; Goggins, Michael G. ; Kinzler, Kenneth W. ; Vogelstein, Bert ; Eshleman, James R. ; Hruban, Ralph H. ; Maitra, Anirban
Publisher:Boston: Springer US
Journal title:Annals of surgical oncology, 2013-11, Vol.20 (12), p.3802-3808
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Islands of genomic stability in the face of genetically unstable metastatic cancer
Author / Creator:Bowland, Kirsten ; Lai, Jiaying ; Skaist, Alyza ; Zhang, Yan ; Teh, Selina Shiqing K ; Roberts, Nicholas J ; Thompson, Elizabeth ; Wheelan, Sarah J ; Hruban, Ralph H ; Karchin, Rachel ; Bailey, Matthew H ; Iacobuzio-Donahue, Christine A ; Eshleman, James R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-12, Vol.19 (12), p.e0298490
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ArticlesFull Text
Cytosine Deamination Is a Major Cause of Baseline Noise in Next-Generation Sequencing
Author / Creator:Chen, Guoli ; Mosier, Stacy ; Gocke, Christopher D. ; Lin, Ming-Tseh ; Eshleman, James R.
Publisher:Cham: Springer International Publishing
Journal title:Molecular diagnosis & therapy, 2014-10, Vol.18 (5), p.587-593
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Mutant proteins as cancer-specific biomarkers
Author / Creator:Wang, Qing ; Chaerkady, Raghothama ; Wu, Jian ; Hwang, Hee Jung ; Papadopoulos, Nick ; Kopelovich, Levy ; Maitra, Anirban ; Matthaei, Hanno ; Eshleman, James R ; Hruban, Ralph H ; Kinzler, Kenneth W ; Pandey, Akhilesh ; Vogelstein, Bert
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (6), p.2444-2449
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ArticlesPeer ReviewedFull Text
Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers
Author / Creator:Haley, Lisa ; Tseng, Li-Hui ; Zheng, Gang ; Dudley, Jonathan ; Anderson, Derek A ; Azad, Nilofer S ; Gocke, Christopher D ; Eshleman, James R ; Lin, Ming-Tseh
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2015-10, Vol.28 (10), p.1390-1399
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ArticlesPeer ReviewedFull Text
Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion
Author / Creator:Jeong, Yea Ji ; Knutsdottir, Hildur ; Shojaeian, Fatemeh ; Lerner, Michael G ; Wissler, Maria F ; Henriet, Elodie ; Ng, Tammy ; Datta, Shalini ; Navarro-Serer, Bernat ; Chianchiano, Peter ; Kinny-Köster, Benedict ; Zimmerman, Jacquelyn W ; Stein-O'Brien, Genevieve ; Gaida, Matthias M ; Eshleman, James R ; Lin, Ming-Tseh ; Fertig, Elana J ; Ewald, Andrew J ; Bader, Joel S ; Wood, Laura D
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2023-04, Vol.133 (8), p.1-15
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ArticlesPeer ReviewedFull Text
Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool
Author / Creator:Carter, Jamal ; Tseng, Li-Hui ; Zheng, Gang ; Dudley, Jonathan ; Illei, Peter ; Gocke, Christopher D. ; Eshleman, James R. ; Lin, Ming-Tseh
Publisher:Oxford, UK: Oxford University Press
Journal title:American journal of clinical pathology, 2015-10, Vol.144 (4), p.620-628
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ArticlesPeer ReviewedFull Text
Haploinsufficiency of Telomerase Reverse Transcriptase Leads to Anticipation in Autosomal Dominant Dyskeratosis Congenita
Author / Creator:Mary Armanios ; Chen, Jiunn-Liang ; Yen-Pei Christy Chang ; Brodsky, Robert A. ; Anita Hawkins ; Griffin, Constance A. ; James R. Eshleman ; Cohen, Alan R. ; Chakravarti, Aravinda ; Hamosh, Ada ; Greider, Carol W.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2005-11, Vol.102 (44), p.15960-15964
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ArticlesPeer ReviewedFull Text
Test Feasibility of Next-Generation Sequencing Assays in Clinical Mutation Detection of Small Biopsy and Fine Needle Aspiration Specimens
Author / Creator:Zheng, Gang ; Tsai, Harrison ; Tseng, Li-Hui ; Illei, Peter ; Gocke, Christopher D. ; Eshleman, James R. ; Netto, George ; Lin, Ming-Tseh
Publisher:England: Oxford University Press
Journal title:American journal of clinical pathology, 2016-05, Vol.145 (5), p.696-702
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IDH1 and IDH2 mutations in lung adenocarcinomas: Evidences of subclonal evolution
Author / Creator:Rodriguez, Erika F. ; De Marchi, Federico ; Lokhandwala, Parvez M. ; Belchis, Deborah ; Xian, Rena ; Gocke, Christopher D. ; Eshleman, James R. ; Illei, Peter ; Li, Ming‐Tseh
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2020-06, Vol.9 (12), p.4386-4394
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protein therapeutic modality founded on molecular regulation
Author / Creator:Wright, Chapman M ; Wright, R. Clay ; Eshleman, James R ; Ostermeier, Marc
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16206-16211
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ArticlesPeer ReviewedFull Text
Analytical Validation of SOD2 Genotyping
Author / Creator:Debeljak, Marija ; Riel, Stacy ; Lin, Ming-Tseh ; Eshleman, James R ; Paller, Channing J
Publisher:Switzerland: MDPI AG
Journal title:Methods and protocols, 2022-12, Vol.6 (1), p.4
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ArticlesPeer ReviewedFull Text
Advancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy
Author / Creator:Wright, R Clay ; Khakhar, Arjun ; Eshleman, James R ; Ostermeier, Marc
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-11, Vol.9 (11), p.e114032
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ArticlesPeer ReviewedFull Text
Familial and sporadic pancreatic cancer share the same molecular pathogenesis
Author / Creator:Norris, Alexis L. ; Roberts, Nicholas J. ; Jones, Siân ; Wheelan, Sarah J. ; Papadopoulos, Nickolas ; Vogelstein, Bert ; Kinzler, Kenneth W. ; Hruban, Ralph H. ; Klein, Alison P. ; Eshleman, James R.
Publisher:Dordrecht: Springer Netherlands
Journal title:Familial cancer, 2015-03, Vol.14 (1), p.95-103
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Distant metastasis occurs late during the genetic evolution of pancreatic cancer

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Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing

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Clinical detection and categorization of uncommon and concomitant mutations involving BRAF

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The genetics of ductal adenocarcinoma of the pancreas in the year 2020: dramatic progress, but far to go

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Clinical validation of KRAS, BRAF, and EGFR mutation detection using next-generation sequencing

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Fundamentals of pyrosequencing

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Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

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Islands of genomic stability in the face of genetically unstable metastatic cancer

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Cytosine Deamination Is a Major Cause of Baseline Noise in Next-Generation Sequencing

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Mutant proteins as cancer-specific biomarkers

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Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers

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Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion

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Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool

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Haploinsufficiency of Telomerase Reverse Transcriptase Leads to Anticipation in Autosomal Dominant Dyskeratosis Congenita

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Test Feasibility of Next-Generation Sequencing Assays in Clinical Mutation Detection of Small Biopsy and Fine Needle Aspiration Specimens

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IDH1 and IDH2 mutations in lung adenocarcinomas: Evidences of subclonal evolution

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protein therapeutic modality founded on molecular regulation

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Analytical Validation of SOD2 Genotyping

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Advancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy

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Familial and sporadic pancreatic cancer share the same molecular pathogenesis

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