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ArticlesPeer ReviewedFull Text
Exonuclease-enhanced prime editors
Author / Creator:Truong, Dong-Jiunn Jeffery ; Geilenkeuser, Julian ; Wendel, Stephanie Victoria ; Wilming, Julius Clemens Heinrich ; Armbrust, Niklas ; Binder, Eva Maria Hildegard ; Santl, Tobias Heinrich ; Siebenhaar, Annika ; Gruber, Christoph ; Phlairaharn, Teeradon ; Živanić, Milica ; Westmeyer, Gil Gregor
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2024-03, Vol.21 (3), p.455-464
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DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
Author / Creator:Vanpouille-Box, Claire ; Alard, Amandine ; Aryankalayil, Molykutty J. ; Sarfraz, Yasmeen ; Diamond, Julie M. ; Schneider, Robert J. ; Inghirami, Giorgio ; Coleman, C. Norman ; Formenti, Silvia C. ; Demaria, Sandra
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-06, Vol.8 (1), p.15618-15618, Article 15618
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Biallelic mutations in the 3′ exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing
Author / Creator:Lardelli, Rea M ; Schaffer, Ashleigh E ; Eggens, Veerle R C ; Zaki, Maha S ; Grainger, Stephanie ; Sathe, Shashank ; Van Nostrand, Eric L ; Schlachetzki, Zinayida ; Rosti, Basak ; Akizu, Naiara ; Scott, Eric ; Silhavy, Jennifer L ; Heckman, Laura Dean ; Rosti, Rasim Ozgur ; Dikoglu, Esra ; Gregor, Anne ; Guemez-Gamboa, Alicia ; Musaev, Damir ; Mande, Rohit ; Widjaja, Ari ; Shaw, Tim L ; Markmiller, Sebastian ; Marin-Valencia, Isaac ; Davies, Justin H ; de Meirleir, Linda ; Kayserili, Hulya ; Altunoglu, Umut ; Freckmann, Mary Louise ; Warwick, Linda ; Chitayat, David ; Blaser, Susan ; Çağlayan, Ahmet Okay ; Bilguvar, Kaya ; Per, Huseyin ; Fagerberg, Christina ; Christesen, Henrik T ; Kibaek, Maria ; Aldinger, Kimberly A ; Manchester, David ; Matsumoto, Naomichi ; Muramatsu, Kazuhiro ; Saitsu, Hirotomo ; Shiina, Masaaki ; Ogata, Kazuhiro ; Foulds, Nicola ; Dobyns, William B ; Chi, Neil C ; Traver, David ; Spaccini, Luigina ; Bova, Stefania Maria ; Gabriel, Stacey B ; Gunel, Murat ; Valente, Enza Maria ; Nassogne, Marie-Cecile ; Bennett, Eric J ; Yeo, Gene W ; Baas, Frank ; Lykke-Andersen, Jens ; Gleeson, Joseph G
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-03, Vol.49 (3), p.457-464
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A specific domain within the 3′ untranslated region of Usutu virus confers resistance to the exonuclease ISG20
Author / Creator:Zoladek, Jim ; El Kazzi, Priscila ; Caval, Vincent ; Vivet-Boudou, Valérie ; Cannac, Marion ; Davies, Emma L. ; Rossi, Soléna ; Bribes, Inès ; Rouilly, Lucile ; Simonin, Yannick ; Jouvenet, Nolwenn ; Decroly, Etienne ; Paillart, Jean-Christophe ; Wilson, Sam J. ; Nisole, Sébastien
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.8528-15, Article 8528
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Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA
Author / Creator:Lubas, Michal ; Damgaard, Christian K ; Tomecki, Rafal ; Cysewski, Dominik ; Jensen, Torben Heick ; Dziembowski, Andrzej
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2013-07, Vol.32 (13), p.1855-1868
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ArticlesPeer ReviewedFull Text
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus
Author / Creator:Lee-Kirsch, Min Ae ; Gong, Maolian ; Chowdhury, Dipanjan ; Senenko, Lydia ; Engel, Kerstin ; Lee, Young-Ae ; de Silva, Udesh ; Bailey, Suzanna L ; Witte, Torsten ; Vyse, Timothy J ; Kere, Juha ; Pfeiffer, Christiane ; Harvey, Scott ; Wong, Andrew ; Koskenmies, Sari ; Hummel, Oliver ; Rohde, Klaus ; Schmidt, Reinhold E ; Dominiczak, Anna F ; Gahr, Manfred ; Hollis, Thomas ; Perrino, Fred W ; Lieberman, Judy ; Hübner, Norbert
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2007-09, Vol.39 (9), p.1065-1067
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ArticlesPeer ReviewedFull Text
C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy
Author / Creator:Richards, Anna ; van den Maagdenberg, Arn M J M ; Jen, Joanna C ; Kavanagh, David ; Bertram, Paula ; Spitzer, Dirk ; Liszewski, M Kathryn ; Barilla-LaBarca, Maria-Louise ; Terwindt, Gisela M ; Kasai, Yumi ; McLellan, Mike ; Grand, Mark Gilbert ; Vanmolkot, Kaate R J ; de Vries, Boukje ; Wan, Jijun ; Kane, Michael J ; Mamsa, Hafsa ; Schäfer, Ruth ; Stam, Anine H ; Haan, Joost ; de Jong, Paulus T V M ; Storimans, Caroline W ; van Schooneveld, Mary J ; Oosterhuis, Jendo A ; Gschwendter, Andreas ; Dichgans, Martin ; Kotschet, Katya E ; Hodgkinson, Suzanne ; Hardy, Todd A ; Delatycki, Martin B ; Hajj-Ali, Rula A ; Kothari, Parul H ; Nelson, Stanley F ; Frants, Rune R ; Baloh, Robert W ; Ferrari, Michel D ; Atkinson, John P
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2007-09, Vol.39 (9), p.1068-1070
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ArticlesPeer ReviewedFull Text
Human 5′ → 3′ exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites
Author / Creator:West, Steven ; Gromak, Natalia ; Proudfoot, Nick J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2004-11, Vol.432 (7016), p.522-525
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ArticlesPeer ReviewedFull Text
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus
Author / Creator:Crow, Yanick J ; Hayward, Bruce E ; Parmar, Rekha ; Robins, Peter ; Leitch, Andrea ; Ali, Manir ; Black, Deborah N ; van Bokhoven, Hans ; Brunner, Han G ; Hamel, Ben C ; Corry, Peter C ; Cowan, Frances M ; Frints, Suzanne G ; Klepper, Joerg ; Livingston, John H ; Lynch, Sally Ann ; Massey, Roger F ; Meritet, Jean François ; Michaud, Jacques L ; Ponsot, Gerard ; Voit, Thomas ; Lebon, Pierre ; Bonthron, David T ; Jackson, Andrew P ; Barnes, Deborah E ; Lindahl, Tomas
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2006-08, Vol.38 (8), p.917-920
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ArticlesPeer ReviewedFull Text
Exonuclease 1
Author / Creator:Feng, Ming-tao ; Cao, Yi-qun ; Li, De-heng ; Chen, Xin ; Chen, Lei ; Gao, Yang ; Li, Liang- dong ; Zhou, Chang-shuai
Publisher:Dove Medical Press Limited
Journal title:OncoTargets and therapy, 2021-04, Vol.14, p.1033
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ArticlesPeer ReviewedFull Text
Kinetic Features of 3′-5′ Exonuclease Activity of Human AP-Endonuclease APE1
Author / Creator:Kuznetsova, Alexandra A. ; Fedorova, Olga S. ; Kuznetsov, Nikita A.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-08, Vol.23 (9), p.2101
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A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28–let-7 pathway
Author / Creator:Chang, Hao-Ming ; Triboulet, Robinson ; Thornton, James E. ; Gregory, Richard I.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-05, Vol.497 (7448), p.244-248
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Reference EntriesFull Text
exonuclease
Publisher:Oxford University Press
Journal title:A Dictionary of Biomedicine, 2019
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Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication
Author / Creator:Li, You ; Masaki, Takahiro ; Yamane, Daisuke ; McGivern, David R. ; Lemon, Stanley M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (5), p.1881-1886
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Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression
Author / Creator:Hastie, Kathryn M ; Kimberlin, Christopher R ; Zandonatti, Michelle A ; MacRae, Ian J ; Saphire, Erica Ollmann
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (6), p.2396-2401
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Reference EntriesFull Text
exonuclease
Publisher:Oxford University Press
Journal title:A Dictionary of Biology, 2019
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ArticlesPeer ReviewedFull Text
The 3′–5′ exonucleases
Author / Creator:Shevelev, Igor V. ; Hübscher, Ulrich
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2002-05, Vol.3 (5), p.364-376
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One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
Author / Creator:Subissi, Lorenzo ; Posthuma, Clara C ; Collet, Axelle ; Zevenhoven-Dobbe, Jessika C ; Gorbalenya, Alexander E ; Decroly, Etienne ; Snijder, Eric J ; Canard, Bruno ; Imbert, Isabelle
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (37), p.E3900-E3909
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Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease
Author / Creator:Akiyama, Benjamin M. ; Laurence, Hannah M. ; Massey, Aaron R. ; Costantino, David A. ; Xie, Xuping ; Yang, Yujiao ; Shi, Pei-Yong ; Nix, Jay C. ; Beckham, J. David ; Kieft, Jeffrey S.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6316), p.1148-1152
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The CRISPR Associated Protein Cas4 Is a 5′ to 3′ DNA Exonuclease with an Iron-Sulfur Cluster
Author / Creator:Zhang, Jing ; Kasciukovic, Taciana ; White, Malcolm F.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-10, Vol.7 (10), p.e47232-e47232
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Showing 1 to 20 of 4,068 results

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Exonuclease-enhanced prime editors

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DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

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Biallelic mutations in the 3′ exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing

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A specific domain within the 3′ untranslated region of Usutu virus confers resistance to the exonuclease ISG20

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Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA

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Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus

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C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy

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Human 5′ → 3′ exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

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Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

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Exonuclease 1

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Kinetic Features of 3′-5′ Exonuclease Activity of Human AP-Endonuclease APE1

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A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28–let-7 pathway

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exonuclease

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Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication

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Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression

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exonuclease

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The 3′–5′ exonucleases

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One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

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Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease

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The CRISPR Associated Protein Cas4 Is a 5′ to 3′ DNA Exonuclease with an Iron-Sulfur Cluster

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