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ArticlesPeer ReviewedFull Text
Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity
Author / Creator:Dumauthioz, Nina ; Tschumi, Benjamin ; Wenes, Mathias ; Marti, Bastien ; Wang, Haiping ; Franco, Fabien ; Li, Wenhui ; Lopez-Mejia, Isabel C. ; Fajas, Lluis ; Ho, Ping-Chih ; Donda, Alena ; Romero, Pedro ; Zhang, Lianjun
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2021-07, Vol.18 (7), p.1761-1771
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The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes
Author / Creator:Lacroix, Matthieu ; Linares, Laetitia K. ; Rueda-Rincon, Natalia ; Bloch, Katarzyna ; Di Michele, Michela ; De Blasio, Carlo ; Fau, Caroline ; Gayte, Laurie ; Blanchet, Emilie ; Mairal, Aline ; Derua, Rita ; Cardona, Fernando ; Beuzelin, Diane ; Annicotte, Jean-Sebastien ; Pirot, Nelly ; Torro, Adeline ; Tinahones, Francisco J. ; Bernex, Florence ; Bertrand-Michel, Justine ; Langin, Dominique ; Fajas, Lluis ; Swinnen, Johannes V. ; Le Cam, Laurent
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7037-7037, Article 7037
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Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR
Author / Creator:Castellano-Castillo, Daniel ; Denechaud, Pierre-Damien ; Fajas, Lluis ; Moreno-Indias, Isabel ; Oliva-Olivera, Wilfredo ; Tinahones, Francisco ; Queipo-Ortuño, María Isabel ; Cardona, Fernando
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-04, Vol.14 (4), p.e0215083
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E2F transcription factor-1 regulates oxidative metabolism
Author / Creator:Blanchet, Emilie ; Annicotte, Jean-Sébastien ; Lagarrigue, Sylviane ; Aguilar, Victor ; Clapé, Cyrielle ; Chavey, Carine ; Fritz, Vanessa ; Casas, François ; Apparailly, Florence ; Auwerx, Johan ; Fajas, Lluis
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2011-09, Vol.13 (9), p.1146-1152
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miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice
Author / Creator:Clapé, Cyrielle ; Fritz, Vanessa ; Henriquet, Corinne ; Apparailly, Florence ; Fernandez, Pedro Luis ; Iborra, François ; Avancès, Christophe ; Villalba, Martin ; Culine, Stéphane ; Fajas, Lluis
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-10, Vol.4 (10), p.e7542-e7542
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CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer
Author / Creator:Ziegler, Dorian V. ; Parashar, Kanishka ; Leal-Esteban, Lucia ; López-Alcalá, Jaime ; Castro, Wilson ; Zanou, Nadège ; Martinez-Carreres, Laia ; Huber, Katharina ; Berney, Xavier Pascal ; Malagón, María M. ; Roger, Catherine ; Berger, Marie-Agnès ; Gouriou, Yves ; Paone, Giulia ; Gallart-Ayala, Hector ; Sflomos, George ; Ronchi, Carlos ; Ivanisevic, Julijana ; Brisken, Cathrin ; Rieusset, Jennifer ; Irving, Melita ; Fajas, Lluis
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-01, Vol.16 (1), p.541-23, Article 541
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CDK4 is an essential insulin effector in adipocytes
Author / Creator:Lagarrigue, Sylviane ; Lopez-Mejia, Isabel C ; Denechaud, Pierre-Damien ; Escoté, Xavier ; Castillo-Armengol, Judit ; Jimenez, Veronica ; Chavey, Carine ; Giralt, Albert ; Lai, Qiuwen ; Zhang, Lianjun ; Martinez-Carreres, Laia ; Delacuisine, Brigitte ; Annicotte, Jean-Sébastien ; Blanchet, Emilie ; Huré, Sébastien ; Abella, Anna ; Tinahones, Francisco J ; Vendrell, Joan ; Dubus, Pierre ; Bosch, Fatima ; Kahn, C Ronald ; Fajas, Lluis
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-01, Vol.126 (1), p.335-348
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Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs
Author / Creator:Yildiz, Ece ; El Alam, Gaby ; Perino, Alessia ; Jalil, Antoine ; Denechaud, Pierre-Damien ; Huber, Katharina ; Fajas, Lluis ; Auwerx, Johan ; Sorrentino, Giovanni ; Schoonjans, Kristina
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2023-03, Vol.12
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CDK4 is an essential insulin effector in adipocytes
Author / Creator:Lagarrigue, Sylviane ; Lopez-Mejia, Isabel C ; Denechaud, Pierre-Damien ; Escoté, Xavier ; Castillo-Armengol, Judit ; Jimenez, Veronica ; Chavey, Carine ; Giralt, Albert ; Lai, Qiuwen ; Zhang, Lianjun ; Martinez-Carreres, Laia ; Delacuisine, Brigitte ; Annicotte, Jean-Sébastien ; Blanchet, Emilie ; Huré, Sébastien ; Abella, Anna ; Tinahones, Francisco J ; Vendrell, Joan ; Dubus, Pierre ; Bosch, Fatima ; Kahn, C Ronald ; Fajas, Lluis
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-07, Vol.132 (13)
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The CDK4–pRB–E2F1 pathway controls insulin secretion
Author / Creator:Annicotte, Jean-Sébastien ; Blanchet, Emilie ; Chavey, Carine ; Iankova, Irena ; Costes, Safia ; Assou, Said ; Teyssier, Jacques ; Dalle, Stéphane ; Sardet, Claude ; Fajas, Lluis
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2009-08, Vol.11 (8), p.1017-1023
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Oxidative stress‐induced FAK activation contributes to uterine serous carcinoma aggressiveness
Author / Creator:Lopez‐Mejia, Isabel C. ; Pijuan, Jordi ; Navaridas, Raúl ; Santacana, Maria ; Gatius, Sònia ; Velasco, Ana ; Castellà, Gerard ; Panosa, Anaïs ; Cabiscol, Elisa ; Pinyol, Miquel ; Coll, Laura ; Bonifaci, Núria ; Peña, Laura Plata ; Vidal, August ; Villanueva, Alberto ; Gari, Eloi ; Llobet‐Navàs, David ; Fajas, Lluis ; Matias‐Guiu, Xavier ; Yeramian, Andrée
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2023-01, Vol.17 (1), p.98-118
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Chromatin immunoprecipitation improvements for the processing of small frozen pieces of adipose tissue
Author / Creator:Castellano-Castillo, Daniel ; Denechaud, Pierre-Damien ; Moreno-Indias, Isabel ; Tinahones, Francisco ; Fajas, Lluis ; Queipo-Ortuño, María Isabel ; Cardona, Fernando
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-02, Vol.13 (2), p.e0192314-e0192314
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The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway
Author / Creator:Khan, Abrar Ul Haq ; Allende-Vega, Nerea ; Gitenay, Delphine ; Gerbal-Chaloin, Sabine ; Gondeau, Claire ; Vo, Dang-Nghiem ; Belkahla, Sana ; Orecchioni, Stefania ; Talarico, Giovanna ; Bertolini, Francesco ; Bozic, Milica ; Valdivielso, Jose M. ; Bejjani, Fabienne ; Jariel, Isabelle ; Lopez-Mejia, Isabel C. ; Fajas, Lluis ; Lecellier, Charles-Henri ; Hernandez, Javier ; Daujat, Martine ; Villalba, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-09, Vol.7 (1), p.10654-15, Article 10654
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The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene
Author / Creator:Annicotte, Jean-Sébastien ; Chavey, Carine ; Servant, Nadège ; Teyssier, Jacques ; Bardin, Aurélie ; Licznar, Anne ; Badia, Eric ; Pujol, Pascal ; Vignon, Françoise ; Maudelonde, Thierry ; Lazennec, Gwendal ; Cavailles, Vincent ; Fajas, Lluis
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2005-12, Vol.24 (55), p.8167-8175
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Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging
Author / Creator:Bertrand, Christelle ; Blanchet, Emilie ; Pessemesse, Laurence ; Annicotte, Jean Sébastien ; Feillet-Coudray, Christine ; Chabi, Béatrice ; Levin, Jonathan ; Fajas, Lluis ; Cabello, Gérard ; Wrutniak-Cabello, Chantal ; Casas, François
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e75111-e75111
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Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure
Author / Creator:Dali-Youcef, Nassim ; Mataki, Chikage ; Coste, Agnès ; Messaddeq, Nadia ; Giroud, Sylvain ; Blanc, Stéphane ; Koehl, Christian ; Champy, Marie-France ; Chambon, Pierre ; Fajas, Lluis ; Metzger, Daniel ; Schoonjans, Kristina ; Auwerx, Johan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (25), p.10703-10708
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Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation
Author / Creator:Khan, Abrar Ul Haq ; Salehi, Hamideh ; Alexia, Catherine ; Valdivielso, Jose M ; Bozic, Milica ; Lopez-Mejia, Isabel C ; Fajas, Lluis ; Gerbal-Chaloin, Sabine ; Daujat-Chavanieu, Martine ; Gitenay, Delphine ; Villalba, Martin
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-04, Vol.11 (9), p.1392
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The RIP140 gene is a transcriptional target of E2F1
Author / Creator:Docquier, Aurélie ; Augereau, Patrick ; Lapierre, Marion ; Harmand, Pierre-Olivier ; Badia, Eric ; Annicotte, Jean-Sébastien ; Fajas, Lluis ; Cavaillès, Vincent
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-05, Vol.7 (5), p.e35839-e35839
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The Transcriptional Coactivator Peroxisome Proliferator–Activated Receptor (PPAR)γ Coactivator-1α and the Nuclear Receptor PPARα Control the Expression of Glycerol Kinase and Metabolism Genes Independ...
Author / Creator:Mazzucotelli, Anne ; Viguerie, Nathalie ; Tiraby, Claire ; Annicotte, Jean-Sébastien ; Mairal, Aline ; Klimcakova, Eva ; Lepin, Emmanuelle ; Delmar, Paul ; Dejean, Sébastien ; Tavernier, Geneviève ; Lefort, Corinne ; Hidalgo, Juan ; Pineau, Thierry ; Fajas, Lluis ; Clément, Karine ; Langin, Dominique
Publisher:United States: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2007-10, Vol.56 (10), p.2467-2475
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PPARγ controls cell proliferation and apoptosis in an RB-dependent manner
Author / Creator:Fajas, Lluis ; Egler, Viviane ; Reiter, Raphael ; Miard, Stéphanie ; Lefebvre, Anne-Marie ; Auwerx, Johan
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2003-07, Vol.22 (27), p.4186-4193
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Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity

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The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes

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Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR

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E2F transcription factor-1 regulates oxidative metabolism

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miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice

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CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer

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CDK4 is an essential insulin effector in adipocytes

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Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs

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CDK4 is an essential insulin effector in adipocytes

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The CDK4–pRB–E2F1 pathway controls insulin secretion

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Oxidative stress‐induced FAK activation contributes to uterine serous carcinoma aggressiveness

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Chromatin immunoprecipitation improvements for the processing of small frozen pieces of adipose tissue

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The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway

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The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene

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Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging

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Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure

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Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation

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The RIP140 gene is a transcriptional target of E2F1

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The Transcriptional Coactivator Peroxisome Proliferator–Activated Receptor (PPAR)γ Coactivator-1α and the Nuclear Receptor PPARα Control the Expression of Glycerol Kinase and Metabolism Genes Independ...

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PPARγ controls cell proliferation and apoptosis in an RB-dependent manner

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