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ArticlesPeer ReviewedFull Text
Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection
Author / Creator:Mentzer, Alexander J. ; O’Connor, Daniel ; Bibi, Sagida ; Chelysheva, Irina ; Clutterbuck, Elizabeth A. ; Demissie, Tesfaye ; Dinesh, Tanya ; Edwards, Nick J. ; Felle, Sally ; Feng, Shuo ; Flaxman, Amy L. ; Karp-Tatham, Eleanor ; Li, Grace ; Liu, Xinxue ; Marchevsky, Natalie ; Godfrey, Leila ; Makinson, Rebecca ; Bull, Maireid B. ; Fowler, Jamie ; Alamad, Bana ; Malinauskas, Tomas ; Chong, Amanda Y. ; Sanders, Katherine ; Shaw, Robert H. ; Voysey, Merryn ; Snape, Matthew D. ; Pollard, Andrew J. ; Lambe, Teresa ; Knight, Julian C.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2023-01, Vol.29 (1), p.147-157
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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial
Author / Creator:Emary, Katherine R W ; Golubchik, Tanya ; Aley, Parvinder K ; Ariani, Cristina V ; Angus, Brian ; Bibi, Sagida ; Blane, Beth ; Bonsall, David ; Cicconi, Paola ; Charlton, Sue ; Clutterbuck, Elizabeth A ; Collins, Andrea M ; Cox, Tony ; Darton, Thomas C ; Dold, Christina ; Douglas, Alexander D ; Duncan, Christopher J A ; Ewer, Katie J ; Flaxman, Amy L ; Faust, Saul N ; Ferreira, Daniela M ; Feng, Shuo ; Finn, Adam ; Folegatti, Pedro M ; Fuskova, Michelle ; Galiza, Eva ; Goodman, Anna L ; Green, Catherine M ; Green, Christopher A ; Greenland, Melanie ; Hallis, Bassam ; Heath, Paul T ; Hay, Jodie ; Hill, Helen C ; Jenkin, Daniel ; Kerridge, Simon ; Lazarus, Rajeka ; Libri, Vincenzo ; Lillie, Patrick J ; Ludden, Catherine ; Marchevsky, Natalie G ; Minassian, Angela M ; McGregor, Alastair C ; Mujadidi, Yama F ; Phillips, Daniel J ; Plested, Emma ; Pollock, Katrina M ; Robinson, Hannah ; Smith, Andrew ; Song, Rinn ; Snape, Matthew D ; Sutherland, Rebecca K ; Thomson, Emma C ; Toshner, Mark ; Turner, David P J ; Vekemans, Johan ; Villafana, Tonya L ; Williams, Christopher J ; Hill, Adrian V S ; Lambe, Teresa ; Gilbert, Sarah C ; Voysey, Merryn ; Ramasamy, Maheshi N ; Pollard, Andrew J
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2021-04, Vol.397 (10282), p.1351-1362
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A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial
Author / Creator:Folegatti, Pedro M. ; Harrison, Kate ; Preciado-Llanes, Lorena ; Lopez, Fernando Ramos ; Bittaye, Mustapha ; Kim, Young Chan ; Flaxman, Amy ; Bellamy, Duncan ; Makinson, Rebecca ; Sheridan, Jonathan ; Azar, Sasha R. ; Campos, Rafael Kroon ; Tilley, Mark ; Tran, Nguyen ; Jenkin, Daniel ; Poulton, Ian ; Lawrie, Alison ; Roberts, Rachel ; Berrie, Eleanor ; Rossi, Shannan L. ; Hill, Adrian ; Ewer, Katie J. ; Reyes-Sandoval, Arturo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4636-4636, Article 4636
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Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse
Author / Creator:Flaxman, Amy ; Sebastian, Sarah ; Appelberg, Sofia ; Cha, Kuan M ; Ulaszewska, Marta ; Purushotham, Jyothi ; Gilbride, Ciaran ; Sharpe, Hannah ; Spencer, Alexandra J ; Bibi, Sagida ; Wright, Daniel ; Schmidt, Isabel ; Dowall, Stuart ; Easterbrook, Linda ; Findlay-Wilson, Stephen ; Gilbert, Sarah ; Mirazimi, Ali ; Lambe, Teresa
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-06, Vol.20 (6), p.e1012262
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Methods for Measuring T-Cell Memory to Vaccination: From Mouse to Man
Author / Creator:Flaxman, Amy ; Ewer, Katie J
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2018-07, Vol.6 (3), p.43
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A Multi-Filovirus Vaccine Candidate: Co-Expression of Ebola, Sudan, and Marburg Antigens in a Single Vector
Author / Creator:Sebastian, Sarah ; Flaxman, Amy ; Cha, Kuan M ; Ulaszewska, Marta ; Gilbride, Ciaran ; Sharpe, Hannah ; Wright, Edward ; Spencer, Alexandra J ; Dowall, Stuart ; Hewson, Roger ; Gilbert, Sarah ; Lambe, Teresa
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2020-05, Vol.8 (2), p.241
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Efficacy and Safety of a Modified Vaccinia Ankara-NP+M1 Vaccine Combined with QIV in People Aged 65 and Older: A Randomised Controlled Clinical Trial (INVICTUS)
Author / Creator:Butler, Chris ; Ellis, Chris ; Folegatti, Pedro ; Swayze, Hannah ; Allen, Julie ; Bussey, Louise ; Bellamy, Duncan ; Lawrie, Alison ; Eagling-Vose, Elizabeth ; Yu, Ly-Mee ; Shanyinde, Milensu ; Mair, Catherine ; Flaxman, Amy ; Ewer, Katie ; Gilbert, Sarah ; Evans, Thomas
Publisher:Basel: MDPI AG
Journal title:Vaccines (Basel), 2021-08, Vol.9 (8), p.851
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ArticlesPeer ReviewedFull Text
Safety and Immunogenicity of the Heterosubtypic Influenza A Vaccine MVA-NP+M1 Manufactured on the AGE1.CR.pIX Avian Cell Line
Author / Creator:Folegatti, Pedro M ; Bellamy, Duncan ; Flaxman, Amy ; Mair, Catherine ; Ellis, Chris ; Ramon, Raquel L ; Ramos Lopez, Fernando ; Mitton, Celia ; Baker, Megan ; Poulton, Ian ; Lawrie, Alison ; Roberts, Rachel ; Minassian, Angela ; Ewer, Katie J ; Evans, Thomas G ; Hill, Adrian V S ; Gilbert, Sarah C
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2019-03, Vol.7 (1), p.33
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ArticlesPeer ReviewedFull Text
Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies
Author / Creator:Folegatti, Pedro M ; Flaxman, Amy ; Jenkin, Daniel ; Makinson, Rebecca ; Kingham-Page, Lucy ; Bellamy, Duncan ; Ramos Lopez, Fernando ; Sheridan, Jonathan ; Poulton, Ian ; Aboagye, Jeremy ; Tran, Nguyen ; Mitton, Celia ; Roberts, Rachel ; Lawrie, Alison M ; Hill, Adrian V S ; Ewer, Katie J ; Gilbert, Sarah
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2021-03, Vol.9 (3), p.262
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ArticlesPeer ReviewedFull Text
Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax
Author / Creator:Cabral-Miranda, Gustavo ; Heath, Matthew D ; Mohsen, Mona O ; Gomes, Ariane C ; Engeroff, Paul ; Flaxman, Amy ; Leoratti, Fabiana M S ; El-Turabi, Aadil ; Reyes-Sandoval, Arturo ; Skinner, Murray A ; Kramer, Matthias F ; Bachmann, Martin F
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2017-05, Vol.5 (2), p.10
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ArticlesPeer ReviewedFull Text
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
Author / Creator:van Doremalen, Neeltje ; Lambe, Teresa ; Spencer, Alexandra ; Belij-Rammerstorfer, Sandra ; Purushotham, Jyothi N. ; Port, Julia R. ; Avanzato, Victoria A. ; Bushmaker, Trenton ; Flaxman, Amy ; Ulaszewska, Marta ; Feldmann, Friederike ; Allen, Elizabeth R. ; Sharpe, Hannah ; Schulz, Jonathan ; Holbrook, Myndi ; Okumura, Atsushi ; Meade-White, Kimberly ; Pérez-Pérez, Lizzette ; Edwards, Nick J. ; Wright, Daniel ; Bissett, Cameron ; Gilbride, Ciaran ; Williamson, Brandi N. ; Rosenke, Rebecca ; Long, Dan ; Ishwarbhai, Alka ; Kailath, Reshma ; Rose, Louisa ; Morris, Susan ; Powers, Claire ; Lovaglio, Jamie ; Hanley, Patrick W. ; Scott, Dana ; Saturday, Greg ; de Wit, Emmie ; Gilbert, Sarah C. ; Munster, Vincent J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-10, Vol.586 (7830), p.578-582
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ArticlesPeer ReviewedFull Text
Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial
Author / Creator:Datoo, Mehreen S ; Natama, Magloire H ; Somé, Athanase ; Traoré, Ousmane ; Rouamba, Toussaint ; Bellamy, Duncan ; Yameogo, Prisca ; Valia, Daniel ; Tegneri, Moubarak ; Ouedraogo, Florence ; Soma, Rachidatou ; Sawadogo, Seydou ; Sorgho, Faizatou ; Derra, Karim ; Rouamba, Eli ; Orindi, Benedict ; Ramos Lopez, Fernando ; Flaxman, Amy ; Cappuccini, Federica ; Kailath, Reshma ; Elias, Sean ; Mukhopadhyay, Ekta ; Noe, Andres ; Cairns, Matthew ; Lawrie, Alison ; Roberts, Rachel ; Valéa, Innocent ; Sorgho, Hermann ; Williams, Nicola ; Glenn, Gregory ; Fries, Louis ; Reimer, Jenny ; Ewer, Katie J ; Shaligram, Umesh ; Hill, Adrian V S ; Tinto, Halidou
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2021-05, Vol.397 (10287), p.1809-1818
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ArticlesPeer ReviewedFull Text
Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial
Author / Creator:Folegatti, Pedro M ; Bittaye, Mustapha ; Flaxman, Amy ; Lopez, Fernando Ramos ; Bellamy, Duncan ; Kupke, Alexandra ; Mair, Catherine ; Makinson, Rebecca ; Sheridan, Jonathan ; Rohde, Cornelius ; Halwe, Sandro ; Jeong, Yuji ; Park, Young-Shin ; Kim, Jae-Ouk ; Song, Manki ; Boyd, Amy ; Tran, Nguyen ; Silman, Daniel ; Poulton, Ian ; Datoo, Mehreen ; Marshall, Julia ; Themistocleous, Yrene ; Lawrie, Alison ; Roberts, Rachel ; Berrie, Eleanor ; Becker, Stephan ; Lambe, Teresa ; Hill, Adrian ; Ewer, Katie ; Gilbert, Sarah
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2020-07, Vol.20 (7), p.816-826
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The safety and immunogenicity of a bivalent conjugate vaccine against Salmonella enterica Typhi and Paratyphi A in healthy Indian adults: a phase 1, randomised, active-controlled, double-blind trial
Author / Creator:Kulkarni, Prasad S ; Potey, Anirudha Vyankatesh ; Bharati, Sandesh ; Kunhihitlu, Anil ; Narasimha, Bharath ; Yallapa, Sindhu ; Dharmadhikari, Abhijeet ; Gavade, Vinay ; Kamat, Chandrashekhar D ; Mallya, Asha ; Sarma, Annamraju D ; Goel, Sunil ; Pisal, Sambhaji S ; Poonawalla, Cyrus S ; Venkatesan, Rajaram ; Jones, Elizabeth ; Flaxman, Amy ; Kim, Young Chan ; Pollard, Andrew J ; McLean, Florence ; Pantazi, Eirini ; Dinesh, Tanya ; Atherton, Rachel ; Day, Nicole ; Park, Juyeon ; Sahoo, Sarthak
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2024-04, Vol.403 (10436), p.1554-1562
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ArticlesPeer ReviewedFull Text
Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation
Author / Creator:Das, Sudip ; Lindemann, Claudia ; Young, Bernadette C. ; Muller, Julius ; Österreich, Babett ; Ternette, Nicola ; Winkler, Ann-Cathrin ; Paprotka, Kerstin ; Reinhardt, Richard ; Förstner, Konrad U. ; Allen, Elizabeth ; Flaxman, Amy ; Yamaguchi, Yuko ; Rollier, Christine S. ; van Diemen, Pauline ; Blättner, Sebastian ; Remmele, Christian W. ; Selle, Martina ; Dittrich, Marcus ; Müller, Tobias ; Vogel, Jörg ; Ohlsen, Knut ; Crook, Derrick W. ; Massey, Ruth ; Wilson, Daniel J. ; Rudel, Thomas ; Wyllie, David H. ; Fraunholz, Martin J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (22), p.E3101-E3110
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ArticlesPeer ReviewedFull Text
Divergent trajectories of antiviral memory after SARS-CoV-2 infection
Author / Creator:Tomic, Adriana ; Skelly, Donal T. ; Ogbe, Ane ; O’Connor, Daniel ; Pace, Matthew ; Adland, Emily ; Alexander, Frances ; Ali, Mohammad ; Allott, Kirk ; Azim Ansari, M. ; Belij-Rammerstorfer, Sandra ; Bibi, Sagida ; Blackwell, Luke ; Brown, Anthony ; Brown, Helen ; Cavell, Breeze ; Clutterbuck, Elizabeth A. ; de Silva, Thushan ; Eyre, David ; Lumley, Sheila ; Flaxman, Amy ; Grist, James ; Hackstein, Carl-Philipp ; Halkerston, Rachel ; Harding, Adam C. ; Hill, Jennifer ; James, Tim ; Jay, Cecilia ; Johnson, Síle A. ; Kronsteiner, Barbara ; Lie, Yolanda ; Linder, Aline ; Longet, Stephanie ; Marinou, Spyridoula ; Matthews, Philippa C. ; Mellors, Jack ; Petropoulos, Christos ; Rongkard, Patpong ; Sedik, Cynthia ; Silva-Reyes, Laura ; Smith, Holly ; Stockdale, Lisa ; Taylor, Stephen ; Thomas, Stephen ; Tipoe, Timothy ; Turtle, Lance ; Vieira, Vinicius Adriano ; Wrin, Terri ; Pollard, Andrew J. ; Lambe, Teresa ; Conlon, Chris P. ; Jeffery, Katie ; Travis, Simon ; Goulder, Philip ; Frater, John ; Mentzer, Alex J. ; Stafford, Lizzie ; Carroll, Miles W. ; James, William S. ; Klenerman, Paul ; Barnes, Eleanor ; Dold, Christina ; Dunachie, Susanna J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1251-1251, Article 1251
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Heterogeneous early immune responses to the S. aureus EapH2 antigen induced by gastrointestinal tract colonisation impact the response to subsequent vaccination
Author / Creator:Flaxman, Amy ; Yamaguchi, Yuko ; van Diemen, Pauline M. ; Rollier, Christine ; Allen, Elizabeth ; Elshina, Elizaveta ; Wyllie, David H.
Publisher:Netherlands: Elsevier Ltd
Journal title:Vaccine, 2019-01, Vol.37 (3), p.494-501
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Vaccination with the Staphylococcus aureus secreted proteins EapH1 and EapH2 impacts both S. aureus carriage and invasive disease
Author / Creator:Elshina, Elizaveta ; Allen, Elizabeth R. ; Flaxman, Amy ; van Diemen, Pauline M. ; Milicic, Anita ; Rollier, Christine S. ; Yamaguchi, Yuko ; Wyllie, David H.
Publisher:Netherlands: Elsevier Ltd
Journal title:Vaccine, 2019-01, Vol.37 (3), p.502-509
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Population variation in anti- S. aureus IgG isotypes influences surface protein A mediated immune subversion
Author / Creator:Whitehouse, Julia ; Flaxman, Amy ; Rollier, Christine ; O'Shea, Matthew K ; Fallowfield, Joanne ; Lindsay, Michael ; Gunner, Frances ; Knox, Kyle ; Wyllie, David H ; Yamaguchi, Yuko
Publisher:Netherlands: Elsevier Ltd
Journal title:Vaccine, 2016-04, Vol.34 (15), p.1792-1799
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Jeopardy. 11 Oct. 2022
Author / Creator:Flaxman, Amy M
Publisher:Nexus: The International Henry Miller Journal
Journal title:Nexus : the international Henry Miller journal, 2024-01, Vol.15, p.236
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Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection

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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial

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A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial

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Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse

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Methods for Measuring T-Cell Memory to Vaccination: From Mouse to Man

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A Multi-Filovirus Vaccine Candidate: Co-Expression of Ebola, Sudan, and Marburg Antigens in a Single Vector

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Efficacy and Safety of a Modified Vaccinia Ankara-NP+M1 Vaccine Combined with QIV in People Aged 65 and Older: A Randomised Controlled Clinical Trial (INVICTUS)

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Safety and Immunogenicity of the Heterosubtypic Influenza A Vaccine MVA-NP+M1 Manufactured on the AGE1.CR.pIX Avian Cell Line

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Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

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Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax

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ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

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Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial

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Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial

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The safety and immunogenicity of a bivalent conjugate vaccine against Salmonella enterica Typhi and Paratyphi A in healthy Indian adults: a phase 1, randomised, active-controlled, double-blind trial

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Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation

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Divergent trajectories of antiviral memory after SARS-CoV-2 infection

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Heterogeneous early immune responses to the S. aureus EapH2 antigen induced by gastrointestinal tract colonisation impact the response to subsequent vaccination

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Vaccination with the Staphylococcus aureus secreted proteins EapH1 and EapH2 impacts both S. aureus carriage and invasive disease

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Population variation in anti- S. aureus IgG isotypes influences surface protein A mediated immune subversion

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Jeopardy. 11 Oct. 2022

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