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142 results for Fluorenes+-+pharmacology

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Structure-based inhibitors targeting the alpha-helical domain of the Spiroplasma melliferum histone-like HU protein
Author / Creator:Agapova, Yuliya K. ; Altukhov, Dmitry A. ; Timofeev, Vladimir I. ; Stroylov, Victor S. ; Mityanov, Vitaly S. ; Korzhenevskiy, Dmitry A. ; Vlaskina, Anna V. ; Smirnova, Eugenia V. ; Bocharov, Eduard V. ; Rakitina, Tatiana V.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.15128, Article 15128
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Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CL pro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates [version 2; peer review: 3 appro...
Author / Creator:Chen, Yu Wai ; Yiu, Chin-Pang Bennu ; Wong, Kwok-Yin
Publisher:England: Faculty of 1000 Ltd
Journal title:F1000 research, 2020, Vol.9, p.129
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Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, pha...
Author / Creator:Ogutu, Bernhards ; Yeka, Adoke ; Kusemererwa, Sylvia ; Thompson, Ricardo ; Tinto, Halidou ; Toure, Andre Offianan ; Uthaisin, Chirapong ; Verma, Amar ; Kibuuka, Afizi ; Lingani, Moussa ; Lourenço, Carlos ; Mombo-Ngoma, Ghyslain ; Nduba, Videlis ; N'Guessan, Tiacoh Landry ; Nassa, Guétawendé Job Wilfried ; Nyantaro, Mary ; Tina, Lucas Otieno ; Singh, Piyoosh K ; El Gaaloul, Myriam ; Marrast, Anne Claire ; Chikoto, Havana ; Csermak, Katalin ; Demin, Ivan ; Mehta, Dheeraj ; Pathan, Rashidkhan ; Risterucci, Celine ; Su, Guoqin ; Winnips, Cornelis ; Kaguthi, Grace ; Fofana, Bakary ; Grobusch, Martin Peter
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2023-09, Vol.23 (9), p.1051-1061
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Pamiparib: First Approval
Author / Creator:Markham, Anthony
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2021-07, Vol.81 (11), p.1343-1348
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Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax infection in Ethiopia: A randomized controlled trial
Author / Creator:Abreha, Tesfay ; Hwang, Jimee ; Thriemer, Kamala ; Tadesse, Yehualashet ; Girma, Samuel ; Melaku, Zenebe ; Assef, Ashenafi ; Kassa, Moges ; Chatfield, Mark D. ; Landman, Keren Z. ; Chenet, Stella M. ; Lucchi, Naomi W. ; Udhayakumar, Venkatachalam ; Zhou, Zhiyong ; Shi, Ya Ping ; Kachur, S. Patrick ; Jima, Daddi ; Kebede, Amha ; Solomon, Hiwot ; Mekasha, Addis ; Alemayehu, Bereket Hailegiorgis ; Malone, Joseph L. ; Dissanayake, Gunewardena ; Teka, Hiwot ; Auburn, Sarah ; von Seidlein, Lorenz ; Price, Ric N.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2017-05, Vol.14 (5), p.e1002299-e1002299
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Effects of polycyclic aromatic hydrocarbons on the proliferation and differentiation of placental cells
Author / Creator:Jo, Yun Sung ; Ko, Hyun Sun ; Kim, Ah Young ; Jo, Ha Gyeong ; Kim, Woo Jung ; Choi, Sae Kyung
Publisher:England: BioMed Central Ltd
Journal title:Reproductive biology and endocrinology, 2022-03, Vol.20 (1), p.47-47, Article 47
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Clinical Pharmacokinetics and Pharmacodynamics of Ledipasvir/Sofosbuvir, a Fixed-Dose Combination Tablet for the Treatment of Hepatitis C
Author / Creator:German, Polina ; Mathias, Anita ; Brainard, Diana ; Kearney, Brian P.
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2016-11, Vol.55 (11), p.1337-1351
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Changing Antimalarial Drug Resistance Patterns Identified by Surveillance at Three Sites in Uganda
Author / Creator:Tumwebaze, Patrick ; Tukwasibwe, Stephen ; Taylor, Aimee ; Conrad, Melissa ; Ruhamyankaka, Emmanuel ; Asua, Victor ; Walakira, Andrew ; Nankabirwa, Joaniter ; Yeka, Adoke ; Staedke, Sarah G. ; Greenhouse, Bryan ; Nsobya, Samuel L. ; Kamya, Moses R. ; Dorsey, Grant ; Rosenthal, Philip J.
Publisher:US: Oxford University Press
Journal title:The Journal of infectious diseases, 2017-02, Vol.215 (4), p.631-635
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Analysis of the susceptibility of refractory hepatitis C virus resistant to nonstructural 5A inhibitors
Author / Creator:Toyodome, Ai ; Mawatari, Seiichi ; Eguchi, Hiromi ; Takeda, Midori ; Kumagai, Kotaro ; Taniyama, Ohki ; Ijuin, Sho ; Sakae, Haruka ; Tabu, Kazuaki ; Oda, Kohei ; Ikeda, Masanori ; Ido, Akio
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-07, Vol.14 (1), p.16363-9, Article 16363
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Plasmodium falciparum Drug Resistance Phenotype as Assessed by Patient Antimalarial Drug Levels and Its Association With pfmdr1 Polymorphisms
Author / Creator:Malmberg, Maja ; Ferreira, Pedro E. ; Tarning, Joel ; Ursing, Johan ; Ngasala, Billy ; Björkman, Anders ; Mårtensson, Andreas ; Gil, José P.
Publisher:United States: Oxford University Press
Journal title:The Journal of infectious diseases, 2013-03, Vol.207 (5), p.842-847
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Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis
Author / Creator:Kloprogge, Frank ; Workman, Lesley ; Borrmann, Steffen ; Tékété, Mamadou ; Lefèvre, Gilbert ; Hamed, Kamal ; Piola, Patrice ; Ursing, Johan ; Kofoed, Poul Erik ; Mårtensson, Andreas ; Ngasala, Billy ; Björkman, Anders ; Ashton, Michael ; Friberg Hietala, Sofia ; Aweeka, Francesca ; Parikh, Sunil ; Mwai, Leah ; Davis, Timothy M. E. ; Karunajeewa, Harin ; Salman, Sam ; Checchi, Francesco ; Fogg, Carole ; Newton, Paul N. ; Mayxay, Mayfong ; Deloron, Philippe ; Faucher, Jean François ; Nosten, François ; Ashley, Elizabeth A. ; McGready, Rose ; van Vugt, Michele ; Proux, Stephane ; Price, Ric N. ; Karbwang, Juntra ; Ezzet, Farkad ; Bakshi, Rajesh ; Stepniewska, Kasia ; White, Nicholas J. ; Guerin, Philippe J. ; Barnes, Karen I. ; Tarning, Joel
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2018-06, Vol.15 (6), p.e1002579
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Isolation, Structure Elucidation and Biological Evaluation of Lomaiviticins F–H, Dimeric Benzofluorene Glycosides from Marine-Derived Micromonospora sp. Bacterium
Author / Creator:Zhang, Fan ; Wang, Wenhui ; Braun, Doug R. ; Ananiev, Gene E. ; Liao, Weiting ; Harper, Mary Kay ; Rajski, Scott R. ; Bugni, Tim S.
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2025-02, Vol.23 (2), p.65
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ArticlesPeer ReviewedFull Text
Raptinal bypasses BAX, BAK, and BOK for mitochondrial outer membrane permeabilization and intrinsic apoptosis
Author / Creator:Heimer, Sina ; Knoll, Gertrud ; Schulze-Osthoff, Klaus ; Ehrenschwender, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-07, Vol.10 (8), p.556-13, Article 556
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Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A
Author / Creator:Woo, Christina M. ; Li, Zhenwu ; Paulson, Eric K. ; Herzon, Seth B.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (11), p.2851-2856
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Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations
Author / Creator:Thomford, Nicholas Ekow ; Kellermann, Tracy ; Biney, Robert Peter ; Dixon, Charné ; Nyarko, Samuel Badu ; Ateko, Richmond Owusu ; Ekor, Martins ; Kyei, George B.
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2024-04, Vol.23 (1), p.125-125, Article 125
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Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs
Author / Creator:Bousema, Teun ; Okell, Lucy ; Shekalaghe, Seif ; Griffin, Jamie T ; Omar, Sabah ; Sawa, Patrick ; Sutherland, Colin ; Sauerwein, Robert ; Ghani, Azra C ; Drakeley, Chris
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2010-05, Vol.9 (1), p.136-136, Article 136
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Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine for Treating Uncomplicated Malaria in African Children: A Randomised, Non-Inferiority Trial
Author / Creator:Bassat, Quique ; Mulenga, Modest ; Tinto, Halidou ; Piola, Patrice ; Borrmann, Steffen ; Menéndez, Clara ; Nambozi, Michael ; Valéa, Innocent ; Nabasumba, Carolyn ; Sasi, Philip ; Bacchieri, Antonella ; Corsi, Marco ; Ubben, David ; Talisuna, Ambrose ; D'Alessandro, Umberto
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-11, Vol.4 (11), p.e7871-e7871
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Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin
Author / Creator:Sidhu, Amar Bir Singh ; Uhlemann, Anne-Catrin ; Valderramos, Stephanie G. ; Valderramos, Juan-Carlos ; Krishna, Sanjeev ; Fidock, David A.
Publisher:Chicago, IL: The University of Chicago Press
Journal title:The Journal of infectious diseases, 2006-08, Vol.194 (4), p.528-535
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Joint effects of phenol, chlorophenol pesticide, phthalate, and polycyclic aromatic hydrocarbon on bone mineral density: comparison of four statistical models
Author / Creator:Di, Dongsheng ; Zhang, Ruyi ; Zhou, Haolong ; Wei, Muhong ; Cui, Yuan ; Zhang, Jianli ; Yuan, Tingting ; Liu, Qian ; Zhou, Tingting ; Wang, Qi
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Environmental science and pollution research international, 2023-07, Vol.30 (33), p.80001-80013
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Ledipasvir-Sofosbuvir Plus Ribavirin in Treatment-Naive Patients With Hepatitis C Virus Genotype 3 Infection: An Open-Label Study
Author / Creator:Feld, Jordan J. ; Ramji, Alnoor ; Shafran, Stephen D. ; Willems, Bernard ; Marotta, Paul ; Huchet, Emmanuelle ; Vachon, Marie-Louise ; Svarovskaia, Evguenia S. ; Huang, K. C. ; Hyland, Robert H. ; Yun, Chohee ; Massetto, Benedetta ; Brainard, Diana M. ; McHutchison, John G. ; Tam, Edward ; Bailey, Robert ; Cooper, Curtis ; Yoshida, Eric M. ; Greenbloom, Susan ; Elkhashab, Magdy ; Borgia, Sergio ; Swain, Mark G.
Publisher:United States: Oxford University Press
Journal title:Clinical infectious diseases, 2017-07, Vol.65 (1), p.13-19
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Structure-based inhibitors targeting the alpha-helical domain of the Spiroplasma melliferum histone-like HU protein

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Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CL pro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates [version 2; peer review: 3 appro...

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Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, pha...

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Pamiparib: First Approval

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Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax infection in Ethiopia: A randomized controlled trial

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Effects of polycyclic aromatic hydrocarbons on the proliferation and differentiation of placental cells

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Clinical Pharmacokinetics and Pharmacodynamics of Ledipasvir/Sofosbuvir, a Fixed-Dose Combination Tablet for the Treatment of Hepatitis C

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Changing Antimalarial Drug Resistance Patterns Identified by Surveillance at Three Sites in Uganda

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Analysis of the susceptibility of refractory hepatitis C virus resistant to nonstructural 5A inhibitors

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Plasmodium falciparum Drug Resistance Phenotype as Assessed by Patient Antimalarial Drug Levels and Its Association With pfmdr1 Polymorphisms

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Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

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Isolation, Structure Elucidation and Biological Evaluation of Lomaiviticins F–H, Dimeric Benzofluorene Glycosides from Marine-Derived Micromonospora sp. Bacterium

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Raptinal bypasses BAX, BAK, and BOK for mitochondrial outer membrane permeabilization and intrinsic apoptosis

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Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A

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Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations

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Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs

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Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine for Treating Uncomplicated Malaria in African Children: A Randomised, Non-Inferiority Trial

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Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin

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Joint effects of phenol, chlorophenol pesticide, phthalate, and polycyclic aromatic hydrocarbon on bone mineral density: comparison of four statistical models

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Ledipasvir-Sofosbuvir Plus Ribavirin in Treatment-Naive Patients With Hepatitis C Virus Genotype 3 Infection: An Open-Label Study

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