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Giacani, Lorenzo
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: GAL-HAL, 2022, p.4017-4017
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Giacani, Lorenzo
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: GAL-HAL, 2021, p.3998-3999
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Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete
Author / Creator:Romeis, Emily ; Tantalo, Lauren ; Lieberman, Nicole ; Phung, Quynh ; Greninger, Alex ; Giacani, Lorenzo
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2021-07, Vol.17 (7), p.e1009612-e1009612
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Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis
Author / Creator:Romeis, Emily ; Lieberman, Nicole A. P. ; Molini, Barbara ; Tantalo, Lauren C. ; Chung, Benjamin ; Phung, Quynh ; Avendaño, Carlos ; Vorobieva, Anastassia ; Greninger, Alexander L. ; Giacani, Lorenzo
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-03, Vol.19 (3), p.e1011259
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Analysis of host cell binding specificity mediated by the Tp0136 adhesin of the syphilis agent Treponema pallidum subsp. pallidum
Author / Creator:Djokic, Vitomir ; Giacani, Lorenzo ; Parveen, Nikhat
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-05, Vol.13 (5), p.e0007401-e0007401
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The wide utility of rabbits as models of human diseases
Author / Creator:Esteves, Pedro J ; Abrantes, Joana ; Hanna-Mari Baldauf ; BenMohamed, Lbachir ; Chen, Yuxing ; Christensen, Neil ; González-Gallego, Javier ; Giacani, Lorenzo ; Hu, Jiafen ; Kaplan, Gilla ; Keppler, Oliver T ; Knight, Katherine L ; Xiang-Peng, Kong ; Lanning, Dennis K ; Jacques Le Pendu ; Lemos de Matos, Ana ; Liu, Jia ; Liu, Shuying ; Lopes, Ana M ; Lu, Shan ; Lukehart, Sheila ; Manabe, Yukari C ; Neves, Fabiana ; McFadden, Grant ; Pan, Ruimin ; Peng, Xuwen ; Patricia de Sousa-Pereira ; Pinheiro, Ana ; Rahman, Masmudur ; Ruvoën-Clouet, Natalie ; Selvakumar Subbian ; Maria Jesús Tuñón ; van der Loo, Wessel ; Vaine, Michael ; Via, Laura E ; Wang, Shixia ; Mage, Rose
Publisher:Seoul: Springer Nature B.V
Journal title:Experimental & molecular medicine, 2018-05, Vol.50 (5), p.1-10
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Treponema pallidum subsp. pallidum TP0136 Protein Is Heterogeneous among Isolates and Binds Cellular and Plasma Fibronectin via its NH2-Terminal End
Author / Creator:Ke, Wujian ; Molini, Barbara J. ; Lukehart, Sheila A. ; Giacani, Lorenzo
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2015-03, Vol.9 (3), p.e0003662-e0003662
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Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure
Author / Creator:Lin, Michelle J. ; Haynes, Austin M. ; Addetia, Amin ; Lieberman, Nicole A. P. ; Phung, Quynh ; Xie, Hong ; Nguyen, Tien V. ; Molini, Barbara J. ; Lukehart, Sheila A. ; Giacani, Lorenzo ; Greninger, Alexander L.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2021-09, Vol.15 (9), p.e0009753-e0009753
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Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum
Author / Creator:Haynes, Austin M. ; Fernandez, Mark ; Romeis, Emily ; Mitjà, Oriol ; Konda, Kelika A. ; Vargas, Silver K. ; Eguiluz, Maria ; Caceres, Carlos F. ; Klausner, Jeffrey D. ; Giacani, Lorenzo
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2021-01, Vol.15 (1), p.e0008812-e0008812
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Development of a Multilocus Sequence Typing (MLST) scheme for Treponema pallidum subsp. pertenue: Application to yaws in Lihir Island, Papua New Guinea
Author / Creator:Godornes, Charmie ; Giacani, Lorenzo ; Barry, Alyssa E. ; Mitja, Oriol ; Lukehart, Sheila A.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2017-12, Vol.11 (12), p.e0006113-e0006113
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Ulcerative skin lesions among children in Cameroon: It is not always Yaws
Author / Creator:Ndzomo Ngono, Jean-Philippe ; Tchatchouang, Serges ; Noah Tsanga, Mireille Victorine ; Njih Tabah, Earnest ; Tchualeu, Albert ; Asiedu, Kingsley ; Giacani, Lorenzo ; Eyangoh, Sara ; Crucitti, Tania
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2021-02, Vol.15 (2), p.e0009180-e0009180
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ArticlesPeer ReviewedFull Text
B-Cell Epitope Mapping of the Treponema pallidum Tp0435 Immunodominant Lipoprotein for Peptide-Based Syphilis Diagnostics
Author / Creator:Keane, Jessica L. ; Bose, Mahashweta ; Molini, Barbara J. ; Konda, Kelika A. ; Vargas, Silver K. ; Reyes Diaz, Michael ; Caceres, Carlos F. ; Klausner, Jeffrey D. ; Treger, Rebecca S. ; Giacani, Lorenzo
Publisher:Switzerland: MDPI AG
Journal title:Diagnostics (Basel), 2025-06, Vol.15 (11), p.1443
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Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster
Author / Creator:Arora, Natasha ; Schuenemann, Verena J. ; Jäger, Günter ; Peltzer, Alexander ; Seitz, Alexander ; Herbig, Alexander ; Strouhal, Michal ; Grillová, Linda ; Sánchez-Busó, Leonor ; Kühnert, Denise ; Bos, Kirsten I. ; Davis, Leyla Rivero ; Mikalová, Lenka ; Bruisten, Sylvia ; Komericki, Peter ; French, Patrick ; Grant, Paul R. ; Pando, María A. ; Vaulet, Lucía Gallo ; Fermepin, Marcelo Rodríguez ; Martinez, Antonio ; Centurion Lara, Arturo ; Giacani, Lorenzo ; Norris, Steven J. ; Šmajs, David ; Bosshard, Philipp P. ; González-Candelas, Fernando ; Nieselt, Kay ; Krause, Johannes ; Bagheri, Homayoun C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2016-12, Vol.2 (1), p.16245-16245, Article 16245
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Fine Analysis of Genetic Diversity of the tpr Gene Family among Treponemal Species, Subspecies and Strains
Author / Creator:Centurion-Lara, Arturo ; Giacani, Lorenzo ; Godornes, Charmie ; Molini, Barbara J. ; Brinck Reid, Tara ; Lukehart, Sheila A.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2013-05, Vol.7 (5), p.e2222-e2222
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Sequencing of Treponema pallidum subsp. pallidum from isolate UZ1974 using Anti-Treponemal Antibodies Enrichment: First complete whole genome sequence obtained directly from human clinical material
Author / Creator:Grillová, Linda ; Giacani, Lorenzo ; Mikalová, Lenka ; Strouhal, Michal ; Strnadel, Radim ; Marra, Christina ; Centurion-Lara, Arturo ; Poveda, Lucy ; Russo, Giancarlo ; Čejková, Darina ; Vašků, Vladimír ; Oppelt, Jan ; Šmajs, David
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-08, Vol.13 (8), p.e0202619-e0202619
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Whole Genome Sequence of the Treponema pallidum subsp. endemicum Strain Bosnia A: The Genome Is Related to Yaws Treponemes but Contains Few Loci Similar to Syphilis Treponemes
Author / Creator:Štaudová, Barbora ; Strouhal, Michal ; Zobaníková, Marie ; Čejková, Darina ; Fulton, Lucinda L. ; Chen, Lei ; Giacani, Lorenzo ; Centurion-Lara, Arturo ; Bruisten, Sylvia M. ; Sodergren, Erica ; Weinstock, George M. ; Šmajs, David
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2014-11, Vol.8 (11), p.e3261-e3261
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Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: study protocol
Author / Creator:Osias, Ethan ; Hung, Phoebe ; Giacani, Lorenzo ; Stafylis, Chrysovalantis ; Konda, Kelika A. ; Vargas, Silver K. ; Reyes-Díaz, E. Michael ; Comulada, W. Scott ; Haake, David A. ; Haynes, Austin M. ; Caceres, Carlos F. ; Klausner, Jeffrey D.
Publisher:London: BioMed Central Ltd
Journal title:BMC infectious diseases, 2020-06, Vol.20 (1), p.1-444, Article 444
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Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws
Author / Creator:Giacani, Lorenzo ; Bernstein, Lawrence R. ; Haynes, Austin M. ; Godornes, B. Charmie ; Ciccarese, Giulia ; Drago, Francesco ; Parodi, Aurora ; Valdevit, Sefora ; Anselmi, Luca ; Tomasini, Carlo Francesco ; Baca, Arthur M.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-01, Vol.13 (1), p.e0007076-e0007076
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Author Correction: The wide utility of rabbits as models of human diseases
Author / Creator:Esteves, Pedro J. ; Abrantes, Joana ; Baldauf, Hanna-Mari ; BenMohamed, Lbachir ; Chen, Yuxing ; Christensen, Neil ; González-Gallego, Javier ; Giacani, Lorenzo ; Hu, Jiafen ; Kaplan, Gilla ; Keppler, Oliver T. ; Knight, Katherine L. ; Kong, Xiang-Peng ; Lanning, Dennis K. ; Le Pendu, Jacques ; de Matos, Ana Lemos ; Liu, Jia ; Liu, Shuying ; Lopes, Ana M. ; Lu, Shan ; Lukehart, Sheila ; Manabe, Yukari C. ; Neves, Fabiana ; McFadden, Grant ; Pan, Ruimin ; Peng, Xuwen ; de Sousa-Pereira, Patricia ; Pinheiro, Ana ; Rahman, Masmudur ; Ruvoën-Clouet, Natalie ; Subbian, Selvakumar ; Tuñón, Maria Jesús ; van der Loo, Wessel ; Vaine, Michael ; Via, Laura E. ; Wang, Shixia ; Mage, Rose
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2019, 51(0), , pp.1-1
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Footprint of Positive Selection in Treponema pallidum subsp. pallidum Genome Sequences Suggests Adaptive Microevolution of the Syphilis Pathogen
Author / Creator:Giacani, Lorenzo ; Chattopadhyay, Sujay ; Centurion-Lara, Arturo ; Jeffrey, Brendan M. ; Le, Hoavan T. ; Molini, Barbara J. ; Lukehart, Sheila A. ; Sokurenko, Evgeni V. ; Rockey, Daniel D.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2012-06, Vol.6 (6), p.e1698-e1698
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Giacani, Lorenzo

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Giacani, Lorenzo

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Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

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Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis

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Analysis of host cell binding specificity mediated by the Tp0136 adhesin of the syphilis agent Treponema pallidum subsp. pallidum

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The wide utility of rabbits as models of human diseases

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Treponema pallidum subsp. pallidum TP0136 Protein Is Heterogeneous among Isolates and Binds Cellular and Plasma Fibronectin via its NH2-Terminal End

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Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure

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Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum

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Development of a Multilocus Sequence Typing (MLST) scheme for Treponema pallidum subsp. pertenue: Application to yaws in Lihir Island, Papua New Guinea

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Ulcerative skin lesions among children in Cameroon: It is not always Yaws

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B-Cell Epitope Mapping of the Treponema pallidum Tp0435 Immunodominant Lipoprotein for Peptide-Based Syphilis Diagnostics

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Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster

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Fine Analysis of Genetic Diversity of the tpr Gene Family among Treponemal Species, Subspecies and Strains

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Sequencing of Treponema pallidum subsp. pallidum from isolate UZ1974 using Anti-Treponemal Antibodies Enrichment: First complete whole genome sequence obtained directly from human clinical material

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Whole Genome Sequence of the Treponema pallidum subsp. endemicum Strain Bosnia A: The Genome Is Related to Yaws Treponemes but Contains Few Loci Similar to Syphilis Treponemes

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Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: study protocol

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Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws

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Author Correction: The wide utility of rabbits as models of human diseases

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Footprint of Positive Selection in Treponema pallidum subsp. pallidum Genome Sequences Suggests Adaptive Microevolution of the Syphilis Pathogen

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