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ArticlesPeer ReviewedFull Text
Precise tuning of gene expression levels in mammalian cells
Author / Creator:Michaels, Yale S. ; Barnkob, Mike B. ; Barbosa, Hector ; Baeumler, Toni A. ; Thompson, Mary K. ; Andre, Violaine ; Colin-York, Huw ; Fritzsche, Marco ; Gileadi, Uzi ; Sheppard, Hilary M. ; Knapp, David J. H. F. ; Milne, Thomas A. ; Cerundolo, Vincenzo ; Fulga, Tudor A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-02, Vol.10 (1), p.818-818, Article 818
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Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model
Author / Creator:Philippou, Yiannis ; Sjoberg, Hanna T. ; Murphy, Emma ; Alyacoubi, Said ; Jones, Keaton I. ; Gordon-Weeks, Alex N. ; Phyu, Su ; Parkes, Eileen E. ; Gillies McKenna, W. ; Lamb, Alastair D. ; Gileadi, Uzi ; Cerundolo, Vincenzo ; Scheiblin, David A. ; Lockett, Stephen J. ; Wink, David A. ; Mills, Ian G. ; Hamdy, Freddie C. ; Muschel, Ruth J. ; Bryant, Richard J.
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-09, Vol.123 (7), p.1089-1100
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ArticlesPeer ReviewedFull Text
Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors
Author / Creator:Kandasamy, Matheswaran ; Gileadi, Uzi ; Rijal, Pramila ; Tan, Tiong Kit ; Lee, Lian N ; Chen, Jili ; Prota, Gennaro ; Klenerman, Paul ; Townsend, Alain ; Cerundolo, Vincenzo
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2023-01, Vol.12
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ArticlesPeer ReviewedFull Text
Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models
Author / Creator:Lau, Vivian W. C. ; Mead, Gracie J. ; Varyova, Zofia ; Mazet, Julie M. ; Krishnan, Anagha ; Roberts, Edward W. ; Prota, Gennaro ; Gileadi, Uzi ; Midwood, Kim S. ; Cerundolo, Vincenzo ; Gérard, Audrey
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-01, Vol.16 (1), p.2-19, Article 2
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ArticlesPeer ReviewedFull Text
A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus
Author / Creator:Hutchinson, Sarah ; Sims, Stuart ; O'Hara, Geraldine ; Silk, Jon ; Gileadi, Uzi ; Cerundolo, Vincenzo ; Klenerman, Paul
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-02, Vol.6 (2), p.e14646-e14646
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ArticlesPeer ReviewedFull Text
Assessing the safety, tolerability and efficacy of PLGA-based immunomodulatory nanoparticles in patients with advanced NY-ESO-1-positive cancers: a first-in-human phase I open-label dose-escalation st...
Author / Creator:Creemers, Jeroen H A ; Pawlitzky, Inka ; Grosios, Konstantina ; Gileadi, Uzi ; Middleton, Mark R ; Gerritsen, Winald R ; Mehra, Niven ; Rivoltini, Licia ; Walters, Ian ; Figdor, Carl G ; Ottevanger, Petronella B ; de Vries, I Jolanda M
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2021-11, Vol.11 (11), p.e050725-e050725
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ArticlesPeer ReviewedFull Text
Addendum: Precise tuning of gene expression levels in mammalian cells
Author / Creator:Michaels, Yale S. ; Barnkob, Mike B. ; Barbosa, Hector ; Baeumler, Toni A. ; Thompson, Mary K. ; Andre, Violaine ; Colin-York, Huw ; Fritzsche, Marco ; Gileadi, Uzi ; Sheppard, Hilary M. ; Knapp, David J. H. F. ; Milne, Thomas A. ; Cerundolo, Vincenzo ; Fulga, Tudor A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-06, Vol.10 (1), p.2622-2622, Article 2622
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Publisher Correction: Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells
Author / Creator:Barnkob, Mike B. ; Michaels, Yale S. ; André, Violaine ; Macklin, Philip S. ; Gileadi, Uzi ; Valvo, Salvatore ; Rei, Margarida ; Kulicke, Corinna ; Chen, Ji-Li ; Jain, Vitul ; Woodcock, Victoria K. ; Colin-York, Huw ; Hadjinicolaou, Andreas V. ; Kong, Youxin ; Mayya, Viveka ; Mazet, Julie M. ; Mead, Gracie-Jennah ; Bull, Joshua A. ; Rijal, Pramila ; Pugh, Christopher W. ; Townsend, Alain R. ; Gérard, Audrey ; Olsen, Lars R. ; Fritzsche, Marco ; Fulga, Tudor A. ; Dustin, Michael L. ; Jones, E. Yvonne ; Cerundolo, Vincenzo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-04, Vol.15 (1), p.3448-3448, Article 3448
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ArticlesPeer ReviewedFull Text
Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells
Author / Creator:Barnkob, Mike B. ; Michaels, Yale S. ; André, Violaine ; Macklin, Philip S. ; Gileadi, Uzi ; Valvo, Salvatore ; Rei, Margarida ; Kulicke, Corinna ; Chen, Ji-Li ; Jain, Vitul ; Woodcock, Victoria K. ; Colin-York, Huw ; Hadjinicolaou, Andreas V. ; Kong, Youxin ; Mayya, Viveka ; Mazet, Julie M. ; Mead, Gracie-Jennah ; Bull, Joshua A. ; Rijal, Pramila ; Pugh, Christopher W. ; Townsend, Alain R. ; Gérard, Audrey ; Olsen, Lars R. ; Fritzsche, Marco ; Fulga, Tudor A. ; Dustin, Michael L. ; Jones, E. Yvonne ; Cerundolo, Vincenzo
Publisher:London: Springer Nature
Journal title:Nature communications, 2024-04, Vol.15 (1), p.3173-18, Article 3173
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ArticlesPeer ReviewedFull Text
712 IMPORT-201 (IMP-MEL): a phase 1 first-in-human dose finding/randomized phase 2 study of a novel iNKT agonist (PORT-2) and pembrolizumab for advanced melanoma and non-small cell lung cancer (NSCLC)
Author / Creator:Coupe, Nicholas ; Pinato, David J ; Fairchild, Justin ; Poe, Russell ; Browne, Carri ; Innaimo, Steven ; Thompson, David ; Gileadi, Uzi ; Santo, Carmela De ; Kramer, Robert ; Walters, Ian ; Middleton, Mark R
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A807-A807
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ArticlesPeer ReviewedFull Text
Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation
Author / Creator:Salio, Mariolina ; Ghadbane, Hemza ; Dushek, Omer ; Shepherd, Dawn ; Cypen, Jeremy ; Gileadi, Uzi ; Aichinger, Michael C ; Napolitani, Giorgio ; Qi, Xiaoyang ; van der Merwe, P Anton ; Wojno, Justyna ; Veerapen, Natacha ; Cox, Liam R ; Besra, Gurdyal S ; Yuan, Weiming ; Cresswell, Peter ; Cerundolo, Vincenzo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (49), p.E4753-E4761
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ArticlesPeer ReviewedFull Text
Generation and characterization of HLA-A2 transgenic mice expressing the human TCR 1G4 specific for the HLA-A2 restricted NY-ESO-1157-165 tumor-specific peptide
Author / Creator:Shenderov, Eugene ; Kandasamy, Matheswaran ; Gileadi, Uzi ; Chen, Jili ; Shepherd, Dawn ; Gibbs, James ; Prota, Gennaro ; Silk, Jonathan D ; Yewdell, Jonathan W ; Cerundolo, Vincenzo
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-06, Vol.9 (6)
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ArticlesPeer ReviewedFull Text
Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial receptor LYVE-1
Author / Creator:Johnson, Louise A ; Banerji, Suneale ; Lawrance, William ; Gileadi, Uzi ; Prota, Gennaro ; Holder, Kayla A ; Roshorm, Yaowaluck M ; Hanke, Tomáš ; Cerundolo, Vincenzo ; Gale, Nicholas W ; Jackson, David G
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2017-07, Vol.18 (7), p.762-770
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ArticlesPeer ReviewedFull Text
Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells
Author / Creator:Bedard, Melissa ; Shrestha, Dilip ; Priestman, David A. ; Wang, Yuting ; Schneider, Falk ; Matute, Juan D. ; Iyer, Shankar S. ; Gileadi, Uzi ; Prota, Gennaro ; Kandasamy, Matheswaran ; Veerapen, Natacha ; Besra, Gurdyal ; Fritzsche, Marco ; Zeissig, Sebastian ; Shevchenko, Andrej ; Christianson, John C. ; Platt, Frances M. ; Eggeling, Christian ; Blumberg, Richard S. ; Salio, Mariolina ; Cerundolo, Vincenzo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (47), p.23671-23681
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ArticlesPeer ReviewedFull Text
Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8 + T cells
Author / Creator:Barnkob, Mike B ; Michaels, Yale S ; André, Violaine ; Macklin, Philip S ; Gileadi, Uzi ; Valvo, Salvatore ; Rei, Margarida ; Kulicke, Corinna ; Chen, Ji-Li ; Jain, Vitul ; Woodcock, Victoria K ; Colin-York, Huw ; Hadjinicolaou, Andreas V ; Kong, Youxin ; Mayya, Viveka ; Mazet, Julie M ; Mead, Gracie-Jennah ; Bull, Joshua A ; Rijal, Pramila ; Pugh, Christopher W ; Townsend, Alain R ; Gérard, Audrey ; Olsen, Lars R ; Fritzsche, Marco ; Fulga, Tudor A ; Dustin, Michael L ; Jones, E Yvonne ; Cerundolo, Vincenzo
Publisher:England: Nature Publishing Group UK
Journal title:Nature communications, 2024-04, Vol.15 (1), p.3173-3173
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Conference ProceedingsPeer ReviewedFull Text
745 IMP-MEL: a phase 1 first-in-human dose-finding study of a novel invariant natural killer T-cell agonist (iNKT) IMM60 in advanced melanoma and non-small-cell lung cancer (NSCLC)
Author / Creator:Coupe, Nicholas ; Walters, Ian ; Fairchild, Justin ; Parkes, Matthew ; Thompson, David ; Kramer, Robert ; Gileadi, Uzi ; Middleton, Mark
Publisher:London: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A778-A778
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ArticlesPeer ReviewedFull Text
Generation and characterization of HLA-A2 transgenic mice expressing the human TCR 1G4 specific for the HLA-A2 restricted NY-ESO-1 157-165 tumor-specific peptide
Author / Creator:Shenderov, Eugene ; Kandasamy, Matheswaran ; Gileadi, Uzi ; Chen, Jili ; Shepherd, Dawn ; Gibbs, James ; Prota, Gennaro ; Silk, Jonathan D ; Yewdell, Jonathan W ; Cerundolo, Vincenzo
Publisher:England
Journal title:Journal for immunotherapy of cancer, 2021-06, Vol.9 (6), p.e002544
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ArticlesPeer ReviewedFull Text
Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy
Author / Creator:Silk, Jonathan D ; Hermans, Ian F ; Gileadi, Uzi ; Chong, Tsung Wen ; Shepherd, Dawn ; Salio, Mariolina ; Mathew, Bini ; Schmidt, Richard R ; Lunt, Sarah Jane ; Williams, Kaye J ; Stratford, Ian J ; Harris, Adrian L ; Cerundolo, Vincenzo
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2004-12, Vol.114 (12), p.1800-1811
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ArticlesPeer ReviewedFull Text
Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia
Author / Creator:Armitage, Andrew E. ; Lim, Pei Jin ; Frost, Joe N. ; Pasricha, Sant-Rayn ; Soilleux, Elizabeth J. ; Evans, Emma ; Morovat, Alireza ; Santos, Ana ; Diaz, Rebeca ; Biggs, Daniel ; Davies, Benjamin ; Gileadi, Uzi ; Robbins, Peter A. ; Lakhal-Littleton, Samira ; Drakesmith, Hal
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Journal of innate immunity, 2016-01, Vol.8 (5), p.517-528
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ArticlesPeer ReviewedFull Text
A Dominant Role for the Immunoproteasome in CD8.sup.+ T Cell Responses to Murine Cytomegalovirus
Author / Creator:Hutchinson, Sarah ; Sims, Stuart ; O'Hara, Geraldine ; Silk, Jon ; Gileadi, Uzi ; Cerundolo, Vincenzo ; Klenerman, Paul
Publisher:Public Library of Science
Journal title:PloS one, 2011-02, Vol.6 (2), p.e14646
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Precise tuning of gene expression levels in mammalian cells

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Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model

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Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors

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Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models

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A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus

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Assessing the safety, tolerability and efficacy of PLGA-based immunomodulatory nanoparticles in patients with advanced NY-ESO-1-positive cancers: a first-in-human phase I open-label dose-escalation st...

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Addendum: Precise tuning of gene expression levels in mammalian cells

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Publisher Correction: Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

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Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

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712 IMPORT-201 (IMP-MEL): a phase 1 first-in-human dose finding/randomized phase 2 study of a novel iNKT agonist (PORT-2) and pembrolizumab for advanced melanoma and non-small cell lung cancer (NSCLC)

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Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation

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Generation and characterization of HLA-A2 transgenic mice expressing the human TCR 1G4 specific for the HLA-A2 restricted NY-ESO-1157-165 tumor-specific peptide

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Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial receptor LYVE-1

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Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells

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Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8 + T cells

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745 IMP-MEL: a phase 1 first-in-human dose-finding study of a novel invariant natural killer T-cell agonist (iNKT) IMM60 in advanced melanoma and non-small-cell lung cancer (NSCLC)

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Generation and characterization of HLA-A2 transgenic mice expressing the human TCR 1G4 specific for the HLA-A2 restricted NY-ESO-1 157-165 tumor-specific peptide

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Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy

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Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia

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A Dominant Role for the Immunoproteasome in CD8.sup.+ T Cell Responses to Murine Cytomegalovirus

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