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The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells
Author / Creator:Curt‐Varesano, Aurélie ; Braun, Laurence ; Ranquet, Caroline ; Hakimi, Mohamed‐Ali ; Bougdour, Alexandre
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cellular microbiology, 2016-02, Vol.18 (2), p.151-167
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Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development
Author / Creator:Manickam, Yogavel ; Malhotra, Nipun ; Mishra, Siddhartha ; Babbar, Palak ; Dusane, Abhishek ; Laleu, Benoît ; Bellini, Valeria ; Hakimi, Mohamed-Ali ; Bougdour, Alexandre ; Sharma, Amit
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2022-03, Vol.18 (3), p.e1010363-e1010363
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Toxoplasma exports dense granule proteins beyond the vacuole to the host cell nucleus and rewires the host genome expression
Author / Creator:Bougdour, Alexandre ; Tardieux, Isabelle ; Hakimi, Mohamed‐Ali
Publisher:England: John Wiley & Sons, Inc
Journal title:Cellular microbiology, 2014-03, Vol.16 (3), p.334-343
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Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii
Author / Creator:Kloehn, Joachim ; Oppenheim, Rebecca D. ; Siddiqui, Ghizal ; De Bock, Pieter-Jan ; Kumar Dogga, Sunil ; Coute, Yohann ; Hakimi, Mohamed-Ali ; Creek, Darren J. ; Soldati-Favre, Dominique
Publisher:England: BioMed Central Ltd
Journal title:BMC biology, 2020-06, Vol.18 (1), p.67-67, Article 67
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Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation
Author / Creator:He, Huan ; Brenier-Pinchart, Marie-Pierre ; Braun, Laurence ; Kraut, Alexandra ; Touquet, Bastien ; Couté, Yohann ; Tardieux, Isabelle ; Hakimi, Mohamed-Ali ; Bougdour, Alexandre
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2018-10, Vol.7
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Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis
Author / Creator:Yogavel, Manickam ; Bougdour, Alexandre ; Mishra, Siddhartha ; Malhotra, Nipun ; Chhibber-Goel, Jyoti ; Bellini, Valeria ; Harlos, Karl ; Laleu, Benoît ; Hakimi, Mohamed-Ali ; Sharma, Amit
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-02, Vol.19 (2), p.e1011124-e1011124
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A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment
Author / Creator:Farhat, Dayana C. ; Swale, Christopher ; Dard, Céline ; Cannella, Dominique ; Ortet, Philippe ; Barakat, Mohamed ; Sindikubwabo, Fabien ; Belmudes, Lucid ; De Bock, Pieter-Jan ; Couté, Yohann ; Bougdour, Alexandre ; Hakimi, Mohamed-Ali
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2020-04, Vol.5 (4), p.570-583
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The Toxoplasma gondii F-Box Protein L2 Functions as a Repressor of Stage Specific Gene Expression
Author / Creator:Baptista, Carlos G. ; Hosking, Sarah ; Gas-Pascual, Elisabet ; Ciampossine, Loic ; Abel, Steven ; Hakimi, Mohamed-Ali ; Jeffers, Victoria ; Le Roch, Karine ; West, Christopher M. ; Blader, Ira J.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-05, Vol.20 (5), p.e1012269
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A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma
Author / Creator:Farhat, Dayana C ; Bowler, Matthew W ; Communie, Guillaume ; Pontier, Dominique ; Belmudes, Lucid ; Mas, Caroline ; Corrao, Charlotte ; Couté, Yohann ; Bougdour, Alexandre ; Lagrange, Thierry ; Hakimi, Mohamed-Ali ; Swale, Christopher
Publisher:Cambridge: eLife Science Publications, Ltd
Journal title:eLife, 2021-07, Vol.10
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A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection
Author / Creator:Dard, Céline ; Swale, Christopher ; Brenier-Pinchart, Marie-Pierre ; Farhat, Dayana C. ; Bellini, Valeria ; Robert, Marie Gladys ; Cannella, Dominique ; Pelloux, Hervé ; Tardieux, Isabelle ; Hakimi, Mohamed-Ali
Publisher:England: BioMed Central Ltd
Journal title:BMC biology, 2021-02, Vol.19 (1), p.25-25, Article 25
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Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis
Author / Creator:Palencia, Andrés ; Bougdour, Alexandre ; Brenier‐Pinchart, Marie‐Pierre ; Touquet, Bastien ; Bertini, Rose‐Laurence ; Sensi, Cristina ; Gay, Gabrielle ; Vollaire, Julien ; Josserand, Véronique ; Easom, Eric ; Freund, Yvonne R ; Pelloux, Hervé ; Rosenthal, Philip J ; Cusack, Stephen ; Hakimi, Mohamed‐Ali
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2017-03, Vol.9 (3), p.385-394
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Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
Author / Creator:Sangaré, Lamba Omar ; Alayi, Tchilabalo Dilezitoko ; Westermann, Benoit ; Hovasse, Agnes ; Sindikubwabo, Fabien ; Callebaut, Isabelle ; Werkmeister, Elisabeth ; Lafont, Frank ; Slomianny, Christian ; Hakimi, Mohamed-Ali ; Van Dorsselaer, Alain ; Schaeffer-Reiss, Christine ; Tomavo, Stanislas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-04, Vol.7 (1), p.11191-11191, Article 11191
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The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-κB signalling via EZH2
Author / Creator:Braun, Laurence ; Brenier-Pinchart, Marie-Pierre ; Hammoudi, Pierre-Mehdi ; Cannella, Dominique ; Kieffer-Jaquinod, Sylvie ; Vollaire, Julien ; Josserand, Véronique ; Touquet, Bastien ; Couté, Yohann ; Tardieux, Isabelle ; Bougdour, Alexandre ; Hakimi, Mohamed-Ali
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2019-07, Vol.4 (7), p.1208-1220
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Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites
Author / Creator:Sindikubwabo, Fabien ; Ding, Shuai ; Hussain, Tahir ; Ortet, Philippe ; Barakat, Mohamed ; Baumgarten, Sebastian ; Cannella, Dominique ; Palencia, Andrés ; Bougdour, Alexandre ; Belmudes, Lucid ; Couté, Yohann ; Tardieux, Isabelle ; Botté, Cyrille Y ; Scherf, Artur ; Hakimi, Mohamed-ali
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-11, Vol.6
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A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection
Author / Creator:Sakura, Takaya ; Sindikubwabo, Fabien ; Oesterlin, Lena K. ; Bousquet, Hugo ; Slomianny, Christian ; Hakimi, Mohamed-Ali ; Langsley, Gordon ; Tomavo, Stanislas
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-12, Vol.6 (1), p.38842-38842, Article 38842
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Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for Toxoplasma gondii Proliferation
Author / Creator:Wang, Jiachen ; Dixon, Stacy E. ; Ting, Li-Min ; Liu, Ting-Kai ; Jeffers, Victoria ; Croken, Matthew M. ; Calloway, Myrasol ; Cannella, Dominique ; Ali Hakimi, Mohamed ; Kim, Kami ; Sullivan, William J.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2014-01, Vol.10 (1), p.e1003830
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A Complex Small RNA Repertoire Is Generated by a Plant/Fungal-Like Machinery and Effected by a Metazoan-Like Argonaute in the Single-Cell Human Parasite Toxoplasma gondii
Author / Creator:Braun, Laurence ; Cannella, Dominique ; Ortet, Philippe ; Barakat, Mohamed ; Sautel, Céline F. ; Kieffer, Sylvie ; Garin, Jérôme ; Bastien, Olivier ; Voinnet, Olivier ; Hakimi, Mohamed-Ali
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2010-05, Vol.6 (5), p.e1000920-e1000920
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Assembly of the Novel Five-Component Apicomplexan Multi-Aminoacyl-tRNA Synthetase Complex Is Driven by the Hybrid Scaffold Protein Tg-p43
Author / Creator:van Rooyen, Jason M. ; Murat, Jean-Benjamin ; Hammoudi, Pierre-Mehdi ; Kieffer-Jaquinod, Sylvie ; Coute, Yohann ; Sharma, Amit ; Pelloux, Hervé ; Belrhali, Hassan ; Hakimi, Mohamed-Ali
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-02, Vol.9 (2), p.e89487-e89487
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UAP56 associates with DRM2 and is localized to chromatin in Arabidopsis
Author / Creator:Azevedo, Jacinthe ; Picart, Claire ; Dureau, Laurent ; Pontier, Dominique ; Jaquinod‐Kieffer, Sylvie ; Hakimi, Mohamed‐Ali ; Lagrange, Thierry
Publisher:England: John Wiley & Sons, Inc
Journal title:FEBS open bio, 2019-05, Vol.9 (5), p.973-985
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A Core-BRAF35 Complex Containing Histone Deacetylase Mediates Repression of Neuronal-Specific Genes
Author / Creator:Hakimi, Mohamed-Ali ; Bochar, Daniel A. ; Chenoweth, Josh ; Lane, William S. ; Mandel, Gail ; Shiekhattar, Ramin
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (11), p.7420-7425
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Showing 1 to 20 of 47 results

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The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells

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Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development

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Toxoplasma exports dense granule proteins beyond the vacuole to the host cell nucleus and rewires the host genome expression

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Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii

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Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation

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Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis

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A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment

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The Toxoplasma gondii F-Box Protein L2 Functions as a Repressor of Stage Specific Gene Expression

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A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma

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A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection

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Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

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Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

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The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-κB signalling via EZH2

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Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites

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A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection

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Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for Toxoplasma gondii Proliferation

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A Complex Small RNA Repertoire Is Generated by a Plant/Fungal-Like Machinery and Effected by a Metazoan-Like Argonaute in the Single-Cell Human Parasite Toxoplasma gondii

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Assembly of the Novel Five-Component Apicomplexan Multi-Aminoacyl-tRNA Synthetase Complex Is Driven by the Hybrid Scaffold Protein Tg-p43

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UAP56 associates with DRM2 and is localized to chromatin in Arabidopsis

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A Core-BRAF35 Complex Containing Histone Deacetylase Mediates Repression of Neuronal-Specific Genes

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