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ArticlesPeer ReviewedFull Text
10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer
Author / Creator:Hamdy, Freddie C ; Donovan, Jenny L ; Lane, J. Athene ; Mason, Malcolm ; Metcalfe, Chris ; Holding, Peter ; Davis, Michael ; Peters, Tim J ; Turner, Emma L ; Martin, Richard M ; Oxley, Jon ; Robinson, Mary ; Staffurth, John ; Walsh, Eleanor ; Bollina, Prasad ; Catto, James ; Doble, Andrew ; Doherty, Alan ; Gillatt, David ; Kockelbergh, Roger ; Kynaston, Howard ; Paul, Alan ; Powell, Philip ; Prescott, Stephen ; Rosario, Derek J ; Rowe, Edward ; Neal, David E
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2016-10, Vol.375 (15), p.1415-1424
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Prevention and early detection of prostate cancer
Author / Creator:Cuzick, Jack, Prof ; Thorat, Mangesh A, MBBS ; Andriole, Gerald, Prof ; Brawley, Otis W, Prof ; Brown, Powel H, Prof ; Culig, Zoran, MD ; Eeles, Rosalind A, Prof ; Ford, Leslie G, MD ; Hamdy, Freddie C, Prof ; Holmberg, Lars, Prof ; Ilic, Dragan, PhD ; Key, Timothy J, Prof ; Vecchia, Carlo La, Prof ; Lilja, Hans, Prof ; Marberger, Michael, Prof ; Meyskens, Frank L, Prof ; Minasian, Lori M, MD ; Parker, Chris, MD ; Parnes, Howard L, MD ; Perner, Sven, Prof ; Rittenhouse, Harry, PhD ; Schalken, Jack, Prof ; Schmid, Hans-Peter, Prof ; Schmitz-Dräger, Bernd J, Prof ; Schröder, Fritz H, Prof ; Stenzl, Arnulf, Prof ; Tombal, Bertrand, Prof ; Wilt, Timothy J, Prof ; Wolk, Alicja, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-10, Vol.15 (11), p.e484-e492
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Active monitoring, radical prostatectomy, or radiotherapy for localised prostate cancer: study design and diagnostic and baseline results of the ProtecT randomised phase 3 trial
Author / Creator:Lane, J Athene, PhD ; Donovan, Jenny L, Prof ; Davis, Michael, MSc ; Walsh, Eleanor, MSc ; Dedman, Daniel, MSc ; Down, Liz, BSc ; Turner, Emma L, PhD ; Mason, Malcolm D, Prof ; Metcalfe, Chris, PhD ; Peters, Tim J, Prof ; Martin, Richard M, PhD ; Neal, David E, Prof ; Hamdy, Freddie C, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-09, Vol.15 (10), p.1109-1118
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Automated quality assessment of large digitised histology cohorts by artificial intelligence
Author / Creator:Haghighat, Maryam ; Browning, Lisa ; Sirinukunwattana, Korsuk ; Malacrino, Stefano ; Khalid Alham, Nasullah ; Colling, Richard ; Cui, Ying ; Rakha, Emad ; Hamdy, Freddie C. ; Verrill, Clare ; Rittscher, Jens
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-03, Vol.12 (1), p.5002-5002, Article 5002
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Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers
Author / Creator:Erickson, Andrew ; Figiel, Sandy ; Rajakumar, Timothy ; Rao, Srinivasa ; Yin, Wencheng ; Doultsinos, Dimitrios ; Magnussen, Anette ; Singh, Reema ; Poulose, Ninu ; Bryant, Richard J. ; Cussenot, Olivier ; Hamdy, Freddie C. ; Woodcock, Dan ; Mills, Ian G. ; Lamb, Alastair D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2025-01, Vol.20 (1), p.e0316475
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Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells
Author / Creator:Sekar, Aashika ; Leiblich, Aaron ; Wainwright, S. Mark ; Mendes, Cláudia C. ; Sarma, Dhruv ; Hellberg, Josephine E. E. U. ; Gandy, Carina ; Goberdhan, Deborah C. I. ; Hamdy, Freddie C. ; Wilson, Clive
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2023-06, Vol.19 (6), p.e1010815-e1010815
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Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of tissue heterogeneity on genomic signatures
Author / Creator:Figiel, Sandy ; Yin, Wencheng ; Doultsinos, Dimitrios ; Erickson, Andrew ; Poulose, Ninu ; Singh, Reema ; Magnussen, Anette ; Anbarasan, Thineskrishna ; Teague, Renuka ; He, Mengxiao ; Lundeberg, Joakim ; Loda, Massimo ; Verrill, Clare ; Colling, Richard ; Gill, Pelvender S. ; Bryant, Richard J. ; Hamdy, Freddie C. ; Woodcock, Dan J. ; Mills, Ian G. ; Cussenot, Olivier ; Lamb, Alastair D.
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2023-10, Vol.22 (1), p.162-162, Article 162
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Development of a framework to improve the process of recruitment to randomised controlled trials (RCTs): the SEAR (Screened, Eligible, Approached, Randomised) framework
Author / Creator:Wilson, Caroline ; Rooshenas, Leila ; Paramasivan, Sangeetha ; Elliott, Daisy ; Jepson, Marcus ; Strong, Sean ; Birtle, Alison ; Beard, David J. ; Halliday, Alison ; Hamdy, Freddie C. ; Lewis, Rebecca ; Metcalfe, Chris ; Rogers, Chris A. ; Stein, Robert C. ; Blazeby, Jane M. ; Donovan, Jenny L.
Publisher:England: BioMed Central
Journal title:Current controlled trials in cardiovascular medicine, 2018-01, Vol.19 (1), p.50-50, Article 50
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ArticlesPeer ReviewedFull Text
Impact of PSA testing on secondary care costs in England and Wales: estimates from the Cluster randomised triAl of PSA testing for Prostate cancer (CAP)
Author / Creator:Thorn, Joanna C. ; Turner, Emma L. ; Walsh, Eleanor I. ; Donovan, Jenny L. ; Neal, David E. ; Hamdy, Freddie C. ; Martin, Richard M. ; Noble, Sian M.
Publisher:England: BioMed Central Ltd
Journal title:BMC health services research, 2023-06, Vol.23 (1), p.610-11, Article 610
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ArticlesPeer ReviewedFull Text
Mating induces switch from hormone-dependent to hormone-independent steroid receptor–mediated growth in Drosophila secondary cells
Author / Creator:Leiblich, Aaron ; Hellberg, Josephine E. E. U. ; Sekar, Aashika ; Gandy, Carina ; Mendes, Claudia C. ; Redhai, Siamak ; Mason, John ; Wainwright, Mark ; Marie, Pauline ; Goberdhan, Deborah C. I. ; Hamdy, Freddie C. ; Wilson, Clive
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2019-10, Vol.17 (10), p.e3000145-e3000145
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ArticlesPeer ReviewedFull Text
Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features
Author / Creator:Rao, Srinivasa ; Verrill, Clare ; Cerundolo, Lucia ; Alham, Nasullah Khalid ; Kaya, Zeynep ; O’Hanlon, Miriam ; Hayes, Alicia ; Lambert, Adam ; James, Martha ; Tullis, Iain D. C. ; Niederer, Jane ; Lovell, Shelagh ; Omer, Altan ; Lopez, Francisco ; Leslie, Tom ; Buffa, Francesca ; Bryant, Richard J. ; Lamb, Alastair D. ; Vojnovic, Boris ; Wedge, David C. ; Mills, Ian G. ; Woodcock, Dan J. ; Tomlinson, Ian ; Hamdy, Freddie C.
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2024-02, Vol.16 (1), p.35-18, Article 35
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ArticlesPeer ReviewedFull Text
iTRAQ Identification of Candidate Serum Biomarkers Associated with Metastatic Progression of Human Prostate Cancer
Author / Creator:Rehman, Ishtiaq ; Evans, Caroline A. ; Glen, Adam ; Cross, Simon S. ; Eaton, Colby L. ; Down, Jenny ; Pesce, Giancarlo ; Phillips, Joshua T. ; Yen, Ow Saw ; Thalmann, George N. ; Wright, Phillip C. ; Hamdy, Freddie C.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e30885-e30885
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Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
Author / Creator:Patel, Rachana ; Fleming, Janis ; Mui, Ernest ; Loveridge, Carolyn ; Repiscak, Peter ; Blomme, Arnaud ; Harle, Victoria ; Salji, Mark ; Ahmad, Imran ; Teo, Katy ; Hamdy, Freddie C ; Hedley, Ann ; van den Broek, Niels ; Mackay, Gillian ; Edwards, Joanne ; Sansom, Owen J ; Leung, Hing Y
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2018-04, Vol.10 (4), p.1-n/a
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Stress‐induced Rab11a‐exosomes induce amphiregulin‐mediated cetuximab resistance in colorectal cancer
Author / Creator:Mason, John D. ; Marks, Ewan ; Fan, Shih‐Jung ; McCormick, Kristie ; Wilson, Clive ; Harris, Adrian L. ; Hamdy, Freddie C. ; Cunningham, Chris ; Goberdhan, Deborah C. I.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Journal of extracellular vesicles, 2024-06, Vol.13 (6), p.e12465-n/a
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Prostate cancer detection after atypical small acinar proliferation (ASAP): A 10‐year single‐centre cohort
Author / Creator:Anbarasan, Thineskrishna ; Raslan, Mutie ; Ghosh, Kanchan ; Macklin, Philip ; Mercader, Claudia ; Leslie, Tom ; Hamdy, Freddie C. ; Colling, Richard ; Browning, Lisa ; Roberts, Ian ; Verrill, Clare ; Bryant, Richard J. ; Lopez, Francisco ; Lamb, Alastair D.
Publisher:United States: John Wiley & Sons, Inc
Journal title:BJUI compass, 2024-09, Vol.5 (9), p.834-836
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Polymorphisms of an Innate Immune Gene, Toll-Like Receptor 4, and Aggressive Prostate Cancer Risk: A Systematic Review and Meta-Analysis
Author / Creator:Weng, Pei-Hsuan ; Huang, Yi-Ling ; Page, John H. ; Chen, Jen-Hau ; Xu, Jianfeng ; Koutros, Stella ; Berndt, Sonja ; Chanock, Stephen ; Yeager, Meredith ; Witte, John S. ; Eeles, Rosalind A. ; Easton, Douglas F. ; Neal, David E. ; Donovan, Jenny ; Hamdy, Freddie C. ; Muir, Kenneth R. ; Giles, Graham ; Severi, Gianluca ; Smith, Jeffrey R. ; Balistreri, Carmela R. ; Shui, Irene M. ; Chen, Yen-Ching
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-10, Vol.9 (10), p.e110569-e110569
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Ductal adenocarcinoma of the prostate: A systematic review and meta‐analysis of incidence, presentation, prognosis, and management
Author / Creator:Ranasinha, Nithesh ; Omer, Altan ; Philippou, Yiannis ; Harriss, Eli ; Davies, Lucy ; Chow, Ken ; Chetta, Paolo M. ; Erickson, Andrew ; Rajakumar, Timothy ; Mills, Ian G. ; Bryant, Richard J. ; Hamdy, Freddie C. ; Murphy, Declan G. ; Loda, Massimo ; Hovens, Christopher M. ; Corcoran, Niall M. ; Verrill, Clare ; Lamb, Alastair D.
Publisher:United States: John Wiley & Sons, Inc
Journal title:BJUI compass, 2021-01, Vol.2 (1), p.13-23
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Validating the use of Hospital Episode Statistics data and comparison of costing methodologies for economic evaluation: an end-of-life case study from the Cluster randomised triAl of PSA testing for P...
Author / Creator:Thorn, Joanna C ; Turner, Emma L ; Hounsome, Luke ; Walsh, Eleanor ; Down, Liz ; Verne, Julia ; Donovan, Jenny L ; Neal, David E ; Hamdy, Freddie C ; Martin, Richard M ; Noble, Sian M
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2016-04, Vol.6 (4), p.e011063-e011063
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Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy
Author / Creator:Gilbert, Rebecca ; Martin, Richard M. ; Evans, David M. ; Tilling, Kate ; Davey Smith, George ; Kemp, John P. ; Lane, J. Athene ; Hamdy, Freddie C. ; Neal, David E. ; Donovan, Jenny L. ; Metcalfe, Chris
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0136735-e0136735
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Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer
Author / Creator:Hamdy, Freddie C. ; Donovan, Jenny L. ; Lane, J. Athene ; Metcalfe, Chris ; Davis, Michael ; Turner, Emma L. ; Martin, Richard M. ; Young, Grace J. ; Walsh, Eleanor I. ; Bryant, Richard J. ; Bollina, Prasad ; Doble, Andrew ; Doherty, Alan ; Gillatt, David ; Gnanapragasam, Vincent ; Hughes, Owen ; Kockelbergh, Roger ; Kynaston, Howard ; Paul, Alan ; Paez, Edgar ; Powell, Philip ; Rosario, Derek J. ; Rowe, Edward ; Mason, Malcolm ; Catto, James W.F. ; Peters, Tim J. ; Oxley, Jon ; Williams, Naomi J. ; Staffurth, John ; Neal, David E.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-04, Vol.388 (17), p.1547-1558
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10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

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Prevention and early detection of prostate cancer

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Active monitoring, radical prostatectomy, or radiotherapy for localised prostate cancer: study design and diagnostic and baseline results of the ProtecT randomised phase 3 trial

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Automated quality assessment of large digitised histology cohorts by artificial intelligence

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Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers

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Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells

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Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of tissue heterogeneity on genomic signatures

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Development of a framework to improve the process of recruitment to randomised controlled trials (RCTs): the SEAR (Screened, Eligible, Approached, Randomised) framework

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Impact of PSA testing on secondary care costs in England and Wales: estimates from the Cluster randomised triAl of PSA testing for Prostate cancer (CAP)

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Mating induces switch from hormone-dependent to hormone-independent steroid receptor–mediated growth in Drosophila secondary cells

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Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features

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iTRAQ Identification of Candidate Serum Biomarkers Associated with Metastatic Progression of Human Prostate Cancer

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Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

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Stress‐induced Rab11a‐exosomes induce amphiregulin‐mediated cetuximab resistance in colorectal cancer

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Prostate cancer detection after atypical small acinar proliferation (ASAP): A 10‐year single‐centre cohort

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Polymorphisms of an Innate Immune Gene, Toll-Like Receptor 4, and Aggressive Prostate Cancer Risk: A Systematic Review and Meta-Analysis

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Ductal adenocarcinoma of the prostate: A systematic review and meta‐analysis of incidence, presentation, prognosis, and management

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Validating the use of Hospital Episode Statistics data and comparison of costing methodologies for economic evaluation: an end-of-life case study from the Cluster randomised triAl of PSA testing for P...

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Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy

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Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

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