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ArticlesPeer ReviewedFull Text
Highly Potent GalNAc-Conjugated Tiny LNA Anti-miRNA-122 Antisense Oligonucleotides
Author / Creator:Yamamoto, Tsuyoshi ; Mukai, Yahiro ; Wada, Fumito ; Terada, Chisato ; Kayaba, Yukina ; Oh, Kaho ; Yamayoshi, Asako ; Obika, Satoshi ; Harada–Shiba, Mariko
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2021-05, Vol.13 (6), p.817
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Association of ceramides in human plasma with risk factors of atherosclerosis
Author / Creator:Ichi, Ikuyo ; Nakahara, Kayoko ; Miyashita, Yavoi ; Hidaka, Atsuko ; Kutsukake, Sahoko ; Inoue, Kana ; Maruyama, Taro ; Miwa, Yoshikazu ; Harada-Shiba, Mariko ; Tsushima, Motoo ; Kojo, Shosuke
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Lipids, 2006-09, Vol.41 (9), p.859-863
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A Low-Frequency APOB p.(Pro955Ser) Variant Contributes to the Severity of/Variability in Familial Hypercholesterolemia
Author / Creator:Hori, Mika ; Takahashi, Atsushi ; Hosoda, Kiminori ; Ogura, Masatsune ; Harada-Shiba, Mariko
Publisher:US: Oxford University Press
Journal title:The journal of clinical endocrinology and metabolism, 2023-02, Vol.108 (2), p.422-432
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Mammary cancer gene therapy targeting lymphangiogenesis : VEGF-C siRNA and soluble VEGF receptor-2, a splicing variant
Author / Creator:Shibata, Masa-Aki ; Ambati, Jayakrishna ; Shibata, Eiko ; Yoshidome, Katsuhide ; Harada-Shiba, Mariko
Publisher:Japan: Springer Japan
Journal title:Medical molecular morphology, 2012-12, Vol.45 (4), p.179-184
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Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry
Author / Creator:Terada, Chisato ; Oh, Kaho ; Tsubaki, Ryutaro ; Chan, Bun ; Aibara, Nozomi ; Ohyama, Kaname ; Shibata, Masa-Aki ; Wada, Takehiko ; Harada-Shiba, Mariko ; Yamayoshi, Asako ; Yamamoto, Tsuyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-12, Vol.14 (1), p.7972-7972, Article 7972
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Multimodality assessment of left ventricular dysfunction in Takayasu arteritis and familial hypercholesterolaemia
Author / Creator:Okada, Atsushi ; Takahama, Hiroyuki ; Ogura, Masatsune ; Morita, Yoshiaki ; Konma, Junichi ; Yoshida, Shuzo ; Makino, Shigeki ; Takashio, Seiji ; Amaki, Makoto ; Ohara, Takahiro ; Hasegawa, Takuya ; Sugano, Yasuo ; Kanzaki, Hideaki ; Harada‐Shiba, Mariko ; Ishibashi‐Ueda, Hatsue ; Yasuda, Satoshi ; Hanafusa, Toshiaki ; Anzai, Toshihisa
Publisher:England: John Wiley & Sons, Inc
Journal title:ESC Heart Failure, 2017-11, Vol.4 (4), p.655-659
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VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body
Author / Creator:Yamamoto, Hideaki ; Takada, Tappei ; Yamanashi, Yoshihide ; Ogura, Masatsune ; Masuo, Yusuke ; Harada-Shiba, Mariko ; Suzuki, Hiroshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), p.633-12, Article 633
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Publisher Correction: Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry
Author / Creator:Terada, Chisato ; Oh, Kaho ; Tsubaki, Ryutaro ; Chan, Bun ; Aibara, Nozomi ; Ohyama, Kaname ; Shibata, Masa-Aki ; Wada, Takehiko ; Harada-Shiba, Mariko ; Yamayoshi, Asako ; Yamamoto, Tsuyoshi
Publisher:London: Springer Science and Business Media LLC
Journal title:Nature Communications, 2024-01, Vol.15 (1), p.271-271, Article 271
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Comparison of Angiogenic, Cytoprotective, and Immunosuppressive Properties of Human Amnion- and Chorion-Derived Mesenchymal Stem Cells
Author / Creator:Yamahara, Kenichi ; Harada, Kazuhiko ; Ohshima, Makiko ; Ishikane, Shin ; Ohnishi, Shunsuke ; Tsuda, Hidetoshi ; Otani, Kentaro ; Taguchi, Akihiko ; Soma, Toshihiro ; Ogawa, Hiroyasu ; Katsuragi, Shinji ; Yoshimatsu, Jun ; Harada-Shiba, Mariko ; Kangawa, Kenji ; Ikeda, Tomoaki
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-02, Vol.9 (2), p.e88319-e88319
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Effects of Dietary Cholesterol on Tissue Ceramides and Oxidation Products of Apolipoprotein B-100 in ApoE-Deficient Mice
Author / Creator:Ichi, Ikuyo ; Adachi, Noriko ; Nakahara, Kayoko ; Kamikawa, Chiaki ; Harada-Shiba, Mariko ; Kojo, Shosuke
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Lipids, 2007-10, Vol.42 (10), p.893-900
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Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy
Author / Creator:Saito, Satoshi ; Yamamoto, Yumi ; Maki, Takakuni ; Hattori, Yorito ; Ito, Hideki ; Mizuno, Katsuhiko ; Harada-Shiba, Mariko ; Kalaria, Raj N. ; Fukushima, Masanori ; Takahashi, Ryosuke ; Ihara, Masafumi
Publisher:England: BioMed Central
Journal title:Acta neuropathologica communications, 2017-04, Vol.5 (1), p.26-26, Article 26
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Serum FABP5 concentration is a potential biomarker for residual risk of atherosclerosis in relation to cholesterol efflux from macrophages
Author / Creator:Furuhashi, Masato ; Ogura, Masatsune ; Matsumoto, Megumi ; Yuda, Satoshi ; Muranaka, Atsuko ; Kawamukai, Mina ; Omori, Akina ; Tanaka, Marenao ; Moniwa, Norihito ; Ohnishi, Hirofumi ; Saitoh, Shigeyuki ; Harada-Shiba, Mariko ; Shimamoto, Kazuaki ; Miura, Tetsuji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.217-217, Article 217
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Mild intrauterine hypoperfusion reproduces neurodevelopmental disorders observed in prematurity
Author / Creator:Ohshima, Makiko ; Coq, Jacques-Olivier ; Otani, Kentaro ; Hattori, Yorito ; Ogawa, Yuko ; Sato, Yoshiaki ; Harada-Shiba, Mariko ; Ihara, Masafumi ; Tsuji, Masahiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-12, Vol.6 (1), p.39377-39377, Article 39377
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The benign c.344G > A: p.(Arg115His) variant in the LDLR gene interpreted from a pedigree-based genetic analysis of familial hypercholesterolemia
Author / Creator:Hori, Mika ; Takahashi, Atsushi ; Son, Cheol ; Ogura, Masatsune ; Harada-Shiba, Mariko
Publisher:England: BioMed Central Ltd
Journal title:Lipids in health and disease, 2020-04, Vol.19 (1), p.62-62, Article 62
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Cholesterol–GalNAc Dual Conjugation Strategy for Reducing Renal Distribution of Antisense Oligonucleotides
Author / Creator:Wada, Fumito ; Yamamoto, Tsuyoshi ; Ueda, Tetsuya ; Sawamura, Motoki ; Wada, Shunsuke ; Harada-Shiba, Mariko ; Obika, Satoshi
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Nucleic acid therapeutics, 2018-02, Vol.28 (1), p.5-57
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Antisense Oligonucleotides Targeting Y-Box Binding Protein-1 Inhibit Tumor Angiogenesis by Downregulating Bcl-xL-VEGFR2/-Tie Axes
Author / Creator:Setoguchi, Kiyoko ; Cui, Lin ; Hachisuka, Nobutaka ; Obchoei, Sumalee ; Shinkai, Kentaro ; Hyodo, Fuminori ; Kato, Kiyoko ; Wada, Fumito ; Yamamoto, Tsuyoshi ; Harada-Shiba, Mariko ; Obika, Satoshi ; Nakano, Kenji
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2017-12, Vol.9 (C), p.170-181
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Pathological and molecular analyses of atherosclerotic lesions in ApoE-knockout mice
Author / Creator:Shibata, Masa-Aki ; Shibata, Eiko ; Maemura, Kentaro ; Kondo, Yoichi ; Harada-Shiba, Mariko
Publisher:Tokyo: Springer Japan
Journal title:Medical molecular morphology, 2017-09, Vol.50 (3), p.130-144
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Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel disease
Author / Creator:Yamamoto, Yumi ; Kojima, Katsutoshi ; Taura, Daisuke ; Sone, Masakatsu ; Washida, Kazuo ; Egawa, Naohiro ; Kondo, Takayuki ; Minakawa, Eiko N. ; Tsukita, Kayoko ; Enami, Takako ; Tomimoto, Hidekazu ; Mizuno, Toshiki ; Kalaria, Raj N. ; Inagaki, Nobuya ; Takahashi, Ryosuke ; Harada-Shiba, Mariko ; Ihara, Masafumi ; Inoue, Haruhisa
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2020-03, Vol.13 (1), p.38-38, Article 38
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Intratracheal Gene Transfer of Adrenomedullin Using Polyplex Nanomicelles Attenuates Monocrotaline-induced Pulmonary Hypertension in Rats
Author / Creator:Harada-Shiba, Mariko ; Takamisawa, Itaru ; Miyata, Kanjiro ; Ishii, Takehiko ; Nishiyama, Nobuhiro ; Itaka, Keiji ; Kangawa, Kenji ; Yoshihara, Fumiki ; Asada, Yujiro ; Hatakeyama, Kinta ; Nagaya, Noriya ; Kataoka, Kazunori
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2009-07, Vol.17 (7), p.1180-1186
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Evaluation of Multiple-Turnover Capability of Locked Nucleic Acid Antisense Oligonucleotides in Cell-Free RNase H-Mediated Antisense Reaction and in Mice
Author / Creator:Yamamoto, Tsuyoshi ; Fujii, Naoko ; Yasuhara, Hidenori ; Wada, Shunsuke ; Wada, Fumito ; Shigesada, Naoya ; Harada-Shiba, Mariko ; Obika, Satoshi
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Nucleic acid therapeutics, 2014-08, Vol.24 (4), p.283-290
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Showing 1 to 20 of 41 results

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Highly Potent GalNAc-Conjugated Tiny LNA Anti-miRNA-122 Antisense Oligonucleotides

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Association of ceramides in human plasma with risk factors of atherosclerosis

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A Low-Frequency APOB p.(Pro955Ser) Variant Contributes to the Severity of/Variability in Familial Hypercholesterolemia

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Mammary cancer gene therapy targeting lymphangiogenesis : VEGF-C siRNA and soluble VEGF receptor-2, a splicing variant

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Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

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Multimodality assessment of left ventricular dysfunction in Takayasu arteritis and familial hypercholesterolaemia

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VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body

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Publisher Correction: Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

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Comparison of Angiogenic, Cytoprotective, and Immunosuppressive Properties of Human Amnion- and Chorion-Derived Mesenchymal Stem Cells

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Effects of Dietary Cholesterol on Tissue Ceramides and Oxidation Products of Apolipoprotein B-100 in ApoE-Deficient Mice

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Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy

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Serum FABP5 concentration is a potential biomarker for residual risk of atherosclerosis in relation to cholesterol efflux from macrophages

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Mild intrauterine hypoperfusion reproduces neurodevelopmental disorders observed in prematurity

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The benign c.344G > A: p.(Arg115His) variant in the LDLR gene interpreted from a pedigree-based genetic analysis of familial hypercholesterolemia

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Cholesterol–GalNAc Dual Conjugation Strategy for Reducing Renal Distribution of Antisense Oligonucleotides

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Antisense Oligonucleotides Targeting Y-Box Binding Protein-1 Inhibit Tumor Angiogenesis by Downregulating Bcl-xL-VEGFR2/-Tie Axes

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Pathological and molecular analyses of atherosclerotic lesions in ApoE-knockout mice

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Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel disease

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Intratracheal Gene Transfer of Adrenomedullin Using Polyplex Nanomicelles Attenuates Monocrotaline-induced Pulmonary Hypertension in Rats

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Evaluation of Multiple-Turnover Capability of Locked Nucleic Acid Antisense Oligonucleotides in Cell-Free RNase H-Mediated Antisense Reaction and in Mice

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