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ArticlesPeer ReviewedFull Text
7-Geranyloxycinnamic Acid Isolated from Melicope lunu-ankenda Leaves Perturbs Colon Cancer and Breast Cancer Cell Lines’ Growth via Induction of Apoptotic Pathway
Author / Creator:Eliaser, Enas Mohamed ; Mohd. Hashim, Najihah ; Rukayadi, Yaya ; Abdull Razis, Ahmad Faizal
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-04, Vol.28 (8), p.3612
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Morindone from Morinda citrifolia as a potential antiproliferative agent against colorectal cancer cell lines
Author / Creator:Chee, Cheok Wui ; Zamakshshari, Nor Hisam ; Lee, Vannajan Sanghiran ; Abdullah, Iskandar ; Othman, Rozana ; Lee, Yean Kee ; Mohd Hashim, Najihah ; Nor Rashid, Nurshamimi
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2022-07, Vol.17 (7), p.e0270970-e0270970
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Phytochemical Constituents and Biological Activities of Melicope lunu-ankenda
Author / Creator:Mohamed Eliaser, Enas ; Hui Ho, Jun ; Mohd. Hashim, Najihah ; Rukayadi, Yaya ; Lian Ee, Gwendoline Cheng ; Abdull Razis, Ahmad Faizal
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-10, Vol.23 (10), p.2708
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Pulchrin A, a New Natural Coumarin Derivative of Enicosanthellum pulchrum, Induces Apoptosis in Ovarian Cancer Cells via Intrinsic Pathway
Author / Creator:Nordin, Noraziah ; Fadaeinasab, Mehran ; Mohan, Syam ; Mohd Hashim, Najihah ; Othman, Rozana ; Karimian, Hamed ; Iman, Venus ; Ramli, Noorlela ; Mohd Ali, Hapipah ; Abdul Majid, Nazia
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-05, Vol.11 (5), p.e0154023-e0154023
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Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells
Author / Creator:Rahman, Mashitoh Abd ; Ramli, Faiqah ; Karimian, Hamed ; Dehghan, Firouzeh ; Nordin, Noraziah ; Mohd Ali, Hapipah ; Mohan, Syam ; Mohd Hashim, Najihah
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0151466
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Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells via the Wnt/β-Cateni...
Author / Creator:Fani, Somayeh ; Dehghan, Firouzeh ; Karimian, Hamed ; Mun Lo, Kong ; Ebrahimi Nigjeh, Siyamak ; Swee Keong, Yeap ; Soori, Rahman ; May Chow, Kit ; Kamalidehghan, Behnam ; Mohd Ali, Hapipah ; Mohd Hashim, Najihah
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-08, Vol.11 (8), p.e0160836
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Ultrastructural Study on the Antibacterial Activity of Artonin E versus Streptomycin against Staphylococcus aureus Strains
Author / Creator:Zajmi, Asdren ; Mohd Hashim, Najihah ; Noordin, Mohamed Ibrahim ; Khalifa, Shaden A. M. ; Ramli, Faiqah ; Mohd Ali, Hapipah ; El-Seedi, Hesham R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0128157-e0128157
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Synthesis, structural characterization, and anticancer activity of a monobenzyltin compound against MCF-7 breast cancer cells
Author / Creator:Fani, Somayeh ; Kamalidehghan, Behnam ; Lo, Kong Mun ; Mohd Hashim, Najihah ; Ahmadipour, Fatemeh ; May Chow, Kit
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2015-01, Vol.9, p.6191-6201
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Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells
Author / Creator:Etti, Imaobong ; Rasedee, Abdullah ; Mohd Hashim, Najihah ; Bustamam Bin Abdul, Ahmad ; Abdul Kadir, Arifah ; Yeap, Swee Keong ; Waziri, Peter ; Malami, Ibrahim ; Lim, Kian Lam ; Etti, Christopher
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2017, Vol.11, p.865-879
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ArticlesPeer ReviewedFull Text
Chemical profiling and biological activity of Peperomia blanda (Jacq.) Kunth
Author / Creator:Al-Madhagi, Wafa M. ; Mohd Hashim, Najihah ; Awad Ali, Nasser A. ; Alhadi, Abeer A. ; Abdul Halim, Siti Nadiah ; Othman, Rozana
Publisher:United States: PeerJ, Inc
Journal title:PeerJ (San Francisco, CA), 2018-06, Vol.6, p.e4839-e4839, Article e4839
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ArticlesPeer ReviewedFull Text
Methanol leaf extract of Actinodaphne sesquipedalis (Lauraceae) enhances gastric defense against ethanol-induced ulcer in rats
Author / Creator:Omar, Hanita ; Nordin, Noraziah ; Hassandarvish, Pouya ; Hajrezaie, Maryam ; Azizan, Ainnul Hamidah Syahadah ; Fadaeinasab, Mehran ; Abdul Majid, Nazia ; Abdulla, Mahmood ; Mohd Hashim, Najihah ; Mohd Ali, Hapipah
Publisher:New Zealand: Taylor & Francis Ltd
Journal title:Drug design, development and therapy, 2017, Vol.11, p.1353-1365
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ArticlesPeer ReviewedFull Text
In vitro assessment of anti-proliferative effect induced by α -mangostin from Cratoxylum arborescens on HeLa cells
Author / Creator:El habbash, Aisha I. ; Mohd Hashim, Najihah ; Ibrahim, Mohamed Yousif ; Yahayu, Maizatulakmal ; Omer, Fatima Abd Elmutaal ; Abd Rahman, Mashitoh ; Nordin, Noraziah ; Lian, Gwendoline Ee Cheng
Publisher:United States: PeerJ, Inc
Journal title:PeerJ (San Francisco, CA), 2017-07, Vol.5, p.e3460-e3460, Article e3460
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Evidence of the gastroprotective and anti-Helicobacter pylori activities of β-mangostin isolated from Cratoxylum arborescens (vahl) blume
Author / Creator:Sidahmed, Heyam ; MOHD HASHIM, NAJIHAH ; Ibrahim Abdelwahab, Siddig ; Mohamed Elhassan Taha, Manal ; Dehghan, Firouzeh ; Loke, Mun Fai ; Vadivelu, Jamuna ; Mohd Hashim, Najihah ; Yahayu, Maizatulakmal ; Syam, Mohan
Publisher:New Zealand: Taylor & Francis Ltd
Journal title:Drug design, development and therapy, 2016-01, Vol.10, p.297-313
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In vivo acute toxicity evaluation and in vitro molecular mechanism study of antiproliferative activity of a novel indole Schiff base β-diiminato manganeseIII complex in hormone-dependent and triple ne...
Author / Creator:Farghadani, Reyhaneh ; Seifaddinipour, Maryam ; Jayakumar Rajarajeswaran ; Mahmood Ameen Abdulla ; Najihah Binti Mohd Hashim ; Si Lay Khaing ; Nur’ain Binti Salehen
Publisher:San Diego: PeerJ, Inc
Journal title:PeerJ (San Francisco, CA), 2019-10, Vol.7, p.e7686-e7686
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RNA Sequencing and Bioinformatics Analysis Reveals the Downregulation of DNA Replication Genes by Morindone in Colorectal Cancer Cells
Author / Creator:Chee, Cheok Wui ; Mohd Hashim, Najihah ; Abdullah, Iskandar ; Nor Rashid, Nurshamimi
Publisher:New York: Springer US
Journal title:Applied biochemistry and biotechnology, 2024-06, Vol.196 (6), p.3216-3233
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α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and Hsp70 protein modulation in vitro, and tumor reduction in vivo
Author / Creator:Ibrahim, Mohamed Yousif ; Ameen Abdulla, Mahmood ; Mohd Ali, Hapipah ; Ee Cheng Lian, Gwendoline ; Arbab, Ismail Adam ; Yahayu, Maizatulakmal ; Dehghan, Firouzeh ; Zeenelabdin Ali, Landa ; Kamalidehghan, Behnam ; Ghaderian, Mostafa ; Mohan, Syam ; Mohd Hashim, Najihah ; Ahmadipour, Fatemeh
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2014-01, Vol.8, p.1629-1647
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Involvement of NF-ΚB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens
Author / Creator:Ibrahim, Mohamed Yousif ; Mohd Ali, Hapipah ; Mohd Hashim, Najihah ; Mohan, Syam ; Ibrahim Abdelwahab, Siddig ; Kamalidehghan, Behnam ; Ghaderian, Mostafa ; Dehghan, Firouzeh ; Zeenelabdin Ali, Landa ; Karimian, Hamed ; Yahayu, Maizatulakmal ; Ee Cheng Lian, Gwendoline ; Ameen Abdulla, Mahmood ; Farjam, Abdoreza Soleimani
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2014-01, Vol.8, p.2193-2211
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Antisecretory, Gastroprotective, Antioxidant and Anti-Helicobcter Pylori Activity of Zerumbone from Zingiber Zerumbet (L.) Smith
Author / Creator:Sidahmed, Heyam Mohamed Ali ; Hashim, Najihah Mohd ; Abdulla, Mahmood Ameen ; Ali, Hapipah Mohd ; Mohan, Syam ; Abdelwahab, Siddig Ibrahim ; Taha, Manal Mohamed Elhassan ; Fai, Loke Mun ; Vadivelu, Jamuna
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0121060
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Biodegradable polymeric insulin microneedles – a design and materials perspective review
Author / Creator:Starlin Chellathurai, Melbha ; Mahmood, Syed ; Mohamed Sofian, Zarif ; Wan Hee, Cheng ; Sundarapandian, Ramkanth ; Ahamed, Haja Nazeer ; Kandasamy, C. S. ; Hilles, Ayah R. ; Hashim, Najihah Mohd ; Janakiraman, Ashok Kumar
Publisher:England: Taylor & Francis Ltd
Journal title:Drug delivery, 2024-12, Vol.31 (1), p.2296350-2296350
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Comparison of apoptotic responses in Blastocystis sp. upon treatment with Tongkat Ali and Metronidazole
Author / Creator:Girish, Sonal ; Kumar, Suresh ; Aminudin, Norhaniza ; Hashim, Najihah Mohd
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-04, Vol.11 (1), p.7833-12, Article 7833
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7-Geranyloxycinnamic Acid Isolated from Melicope lunu-ankenda Leaves Perturbs Colon Cancer and Breast Cancer Cell Lines’ Growth via Induction of Apoptotic Pathway

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Morindone from Morinda citrifolia as a potential antiproliferative agent against colorectal cancer cell lines

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Phytochemical Constituents and Biological Activities of Melicope lunu-ankenda

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Pulchrin A, a New Natural Coumarin Derivative of Enicosanthellum pulchrum, Induces Apoptosis in Ovarian Cancer Cells via Intrinsic Pathway

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Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells

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Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells via the Wnt/β-Cateni...

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Ultrastructural Study on the Antibacterial Activity of Artonin E versus Streptomycin against Staphylococcus aureus Strains

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Synthesis, structural characterization, and anticancer activity of a monobenzyltin compound against MCF-7 breast cancer cells

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Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells

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Chemical profiling and biological activity of Peperomia blanda (Jacq.) Kunth

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Methanol leaf extract of Actinodaphne sesquipedalis (Lauraceae) enhances gastric defense against ethanol-induced ulcer in rats

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In vitro assessment of anti-proliferative effect induced by α -mangostin from Cratoxylum arborescens on HeLa cells

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Evidence of the gastroprotective and anti-Helicobacter pylori activities of β-mangostin isolated from Cratoxylum arborescens (vahl) blume

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In vivo acute toxicity evaluation and in vitro molecular mechanism study of antiproliferative activity of a novel indole Schiff base β-diiminato manganeseIII complex in hormone-dependent and triple ne...

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RNA Sequencing and Bioinformatics Analysis Reveals the Downregulation of DNA Replication Genes by Morindone in Colorectal Cancer Cells

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α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and Hsp70 protein modulation in vitro, and tumor reduction in vivo

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Involvement of NF-ΚB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens

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Antisecretory, Gastroprotective, Antioxidant and Anti-Helicobcter Pylori Activity of Zerumbone from Zingiber Zerumbet (L.) Smith

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Biodegradable polymeric insulin microneedles – a design and materials perspective review

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Comparison of apoptotic responses in Blastocystis sp. upon treatment with Tongkat Ali and Metronidazole

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