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ArticlesPeer ReviewedFull Text
A large size-selective DNA nanopore with sensing applications
Author / Creator:Thomsen, Rasmus P. ; Malle, Mette Galsgaard ; Okholm, Anders Hauge ; Krishnan, Swati ; Bohr, Søren S.-R. ; Sørensen, Rasmus Schøler ; Ries, Oliver ; Vogel, Stefan ; Simmel, Friedrich C. ; Hatzakis, Nikos S. ; Kjems, Jørgen
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5655-10, Article 5655
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Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum
Author / Creator:Laursen, Tomas ; Borch, Jonas ; Knudsen, Camilla ; Bavishi, Krutika ; Torta, Federico ; Martens, Helle Juel ; Silvestro, Daniele ; Hatzakis, Nikos S. ; Wenk, Markus R. ; Dafforn, Timothy R. ; Olsen, Carl Erik ; Motawia, Mohammed Saddik ; Hamberger, Björn ; Møller, Birger Lindberg ; Bassard, Jean-Etienne
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-11, Vol.354 (6314), p.890-893
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Everything, everywhere, almost at once
Author / Creator:Kæstel-Hansen, Jacob ; Hatzakis, Nikos S
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2024-01, Vol.13
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SEMORE: SEgmentation and MORphological fingErprinting by machine learning automates super-resolution data analysis
Author / Creator:Bender, Steen W. B. ; Dreisler, Marcus W. ; Zhang, Min ; Kæstel-Hansen, Jacob ; Hatzakis, Nikos S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-02, Vol.15 (1), p.1763-13, Article 1763
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DeepFRET, a software for rapid and automated single-molecule FRET data classification using deep learning
Author / Creator:Thomsen, Johannes ; Sletfjerding, Magnus Berg ; Jensen, Simon Bo ; Stella, Stefano ; Paul, Bijoya ; Malle, Mette Galsgaard ; Montoya, Guillermo ; Petersen, Troels Christian ; Hatzakis, Nikos S
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-11, Vol.9
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Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells
Author / Creator:Rosholm, Kadla R ; Leijnse, Natascha ; Mantsiou, Anna ; Tkach, Vadym ; Pedersen, Søren L ; Wirth, Volker F ; Oddershede, Lene B ; Jensen, Knud J ; Martinez, Karen L ; Hatzakis, Nikos S ; Bendix, Poul Martin ; Callan-Jones, Andrew ; Stamou, Dimitrios
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2017-07, Vol.13 (7), p.724-729
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Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
Author / Creator:Jensen, Simon Bo ; Thodberg, Sara ; Parween, Shaheena ; Moses, Matias E. ; Hansen, Cecilie C. ; Thomsen, Johannes ; Sletfjerding, Magnus B. ; Knudsen, Camilla ; Del Giudice, Rita ; Lund, Philip M. ; Castaño, Patricia R. ; Bustamante, Yanet G. ; Velazquez, Maria Natalia Rojas ; Jørgensen, Flemming Steen ; Pandey, Amit V. ; Laursen, Tomas ; Møller, Birger Lindberg ; Hatzakis, Nikos S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-04, Vol.12 (1), p.2260-14, Article 2260
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Direct observation of proton pumping by a eukaryotic P-type ATPase
Author / Creator:Veshaguri, Salome ; Christensen, Sune M. ; Kemmer, Gerdi C. ; Ghale, Garima ; Møller, Mads P. ; Lohr, Christina ; Christensen, Andreas L. ; Justesen, Bo H. ; Jørgensen, Ida L. ; Schiller, Jürgen ; Hatzakis, Nikos S. ; Grabe, Michael ; Pomorski, Thomas Günther ; Stamou, Dimitrios
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-03, Vol.351 (6280), p.1469-1473
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ArticlesPeer ReviewedFull Text
The dopamine transporter antiports potassium to increase the uptake of dopamine
Author / Creator:Schmidt, Solveig G. ; Malle, Mette Galsgaard ; Nielsen, Anne Kathrine ; Bohr, Søren S.-R. ; Pugh, Ciara F. ; Nielsen, Jeppe C. ; Poulsen, Ida H. ; Rand, Kasper D. ; Hatzakis, Nikos S. ; Loland, Claus J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2446-2446, Article 2446
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Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation
Author / Creator:Mortensen, Janni Støvring ; Bohr, Søren S.-R. ; Krog, Lasse Skjoldborg ; Bøtker, Johan Peter ; Kapousidou, Vaya ; Saaby, Lasse ; Hatzakis, Nikos S. ; Mørck Nielsen, Hanne ; Nguyen, Duc Ninh ; Rønholt, Stine
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-04, Vol.14 (1), p.7665-7665, Article 7665
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ArticlesPeer ReviewedFull Text
Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strength
Author / Creator:Bavishi, Krutika ; Li, Darui ; Eiersholt, Stine ; Hooley, Emma N. ; Petersen, Troels C. ; Møller, Birger Lindberg ; Hatzakis, Nikos S. ; Laursen, Tomas
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-05, Vol.8 (1), p.6817-9, Article 6817
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Single-Particle Tracking of Thermomyces lanuginosus Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion
Author / Creator:Iversen, Josephine F. ; Bohr, Søren S.-R. ; Pinholt, Henrik D. ; Moses, Matias E. ; Iversen, Lars ; Christensen, Sune M. ; Hatzakis, Nikos S. ; Zhang, Min
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-03, Vol.13 (4), p.631
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Direct Observation of Sophorolipid Micelle Docking in Model Membranes and Cells by Single Particle Studies Reveals Optimal Fusion Conditions
Author / Creator:Singh, Pradeep Kumar ; Bohr, Søren S.-R. ; Hatzakis, Nikos S.
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2020-09, Vol.10 (9), p.1291
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Direct observation of heterogeneous formation of amyloid spherulites in real-time by super-resolution microscopy
Author / Creator:Zhang, Min ; Pinholt, Henrik D. ; Zhou, Xin ; Bohr, Søren S.-R. ; Banetta, Luca ; Zaccone, Alessio ; Foderà, Vito ; Hatzakis, Nikos S.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2022-08, Vol.5 (1), p.850-850, Article 850
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Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies
Author / Creator:Bohr, Freja ; Bohr, Søren S. -R. ; Mishra, Narendra Kumar ; González-Foutel, Nicolás Sebastian ; Pinholt, Henrik Dahl ; Wu, Shunliang ; Nielsen, Emilie Milan ; Zhang, Min ; Kjaergaard, Magnus ; Jensen, Knud J. ; Hatzakis, Nikos S.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2023-02, Vol.6 (1), p.178-14, Article 178
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Single-particle diffusional fingerprinting: A machine-learning framework for quantitative analysis of heterogeneous diffusion
Author / Creator:Pinholt, Henrik D. ; Bohr, Søren S.-R. ; Iversen, Josephine F. ; Boomsma, Wouter ; Hatzakis, Nikos S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (31), p.1-7
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Single-particle combinatorial multiplexed liposome fusion mediated by DNA
Author / Creator:Malle, Mette Galsgaard ; Löffler, Philipp M. G. ; Bohr, Søren S.-R. ; Sletfjerding, Magnus Berg ; Risgaard, Nikolaj Alexander ; Jensen, Simon Bo ; Zhang, Min ; Hedegård, Per ; Vogel, Stefan ; Hatzakis, Nikos S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2022-05, Vol.14 (5), p.558-565
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How curved membranes recruit amphipathic helices and protein anchoring motifs
Author / Creator:Hatzakis, Nikos S ; Bhatia, Vikram K ; Larsen, Jannik ; Madsen, Kenneth L ; Bolinger, Pierre-Yves ; Kunding, Andreas H ; Castillo, John ; Gether, Ulrik ; Hedegård, Per ; Stamou, Dimitrios
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2009-11, Vol.5 (11), p.835-841
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A systematic analysis of regression models for protein engineering
Author / Creator:Michael, Richard ; Kæstel-Hansen, Jacob ; Mørch Groth, Peter ; Bartels, Simon ; Salomon, Jesper ; Tian, Pengfei ; Hatzakis, Nikos S. ; Boomsma, Wouter
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2024-05, Vol.20 (5), p.e1012061-e1012061
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Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases
Author / Creator:Larsen, Jannik Bruun ; Jensen, Martin Borch ; Bhatia, Vikram K ; Pedersen, Søren L ; Bjørnholm, Thomas ; Iversen, Lars ; Uline, Mark ; Szleifer, Igal ; Jensen, Knud J ; Hatzakis, Nikos S ; Stamou, Dimitrios
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2015-03, Vol.11 (3), p.192-194
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A large size-selective DNA nanopore with sensing applications

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Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum

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Everything, everywhere, almost at once

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SEMORE: SEgmentation and MORphological fingErprinting by machine learning automates super-resolution data analysis

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DeepFRET, a software for rapid and automated single-molecule FRET data classification using deep learning

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Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells

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Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase

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Direct observation of proton pumping by a eukaryotic P-type ATPase

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The dopamine transporter antiports potassium to increase the uptake of dopamine

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Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation

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Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strength

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Single-Particle Tracking of Thermomyces lanuginosus Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion

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Direct Observation of Sophorolipid Micelle Docking in Model Membranes and Cells by Single Particle Studies Reveals Optimal Fusion Conditions

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Direct observation of heterogeneous formation of amyloid spherulites in real-time by super-resolution microscopy

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Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies

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Single-particle diffusional fingerprinting: A machine-learning framework for quantitative analysis of heterogeneous diffusion

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Single-particle combinatorial multiplexed liposome fusion mediated by DNA

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How curved membranes recruit amphipathic helices and protein anchoring motifs

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A systematic analysis of regression models for protein engineering

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Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

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