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79 results for Hexokinase+-+antagonists+

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ArticlesPeer ReviewedFull Text
Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
Author / Creator:DeWaal, Dannielle ; Nogueira, Veronique ; Terry, Alexander R. ; Patra, Krushna C. ; Jeon, Sang-Min ; Guzman, Grace ; Au, Jennifer ; Long, Christopher P. ; Antoniewicz, Maciek R. ; Hay, Nissim
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.446-14, Article 446
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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
Author / Creator:Sukumar, Madhusudhanan ; Liu, Jie ; Ji, Yun ; Subramanian, Murugan ; Crompton, Joseph G. ; Yu, Zhiya ; Roychoudhuri, Rahul ; Palmer, Douglas C. ; Muranski, Pawel ; Karoly, Edward D. ; Mohney, Robert P. ; Klebanoff, Christopher A. ; Lal, Ashish ; Finkel, Toren ; Restifo, Nicholas P. ; Gattinoni, Luca
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-10, Vol.123 (10), p.4479-4488
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Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic
Author / Creator:Zhang, Hai-nan ; Yang, Lina ; Ling, Jian-ya ; Czajkowsky, Daniel M. ; Wang, Jing-Fang ; Zhang, Xiao-Wei ; Zhou, Yi-Ming ; Ge, Feng ; Yang, Ming-kun ; Xiong, Qian ; Guo, Shu-Juan ; Le, Huang-Ying ; Wu, Song-Fang ; Yan, Wei ; Liu, Bingya ; Zhu, Heng ; Chen, Zhu ; Tao, Sheng-ce
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (49), p.15084-15089
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Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis
Author / Creator:Zheng, Zhibo ; Ma, He ; Zhang, Xia ; Tu, Fei ; Wang, Xiaohui ; Ha, Tuanzhu ; Fan, Min ; Liu, Li ; Xu, Jingjing ; Yu, Kaijiang ; Wang, Ruitao ; Kalbfleisch, John ; Kao, Race ; Williams, David ; Li, Chuanfu
Publisher:US: Oxford University Press
Journal title:The Journal of infectious diseases, 2017-05, Vol.215 (9), p.1396-1406
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Targeting cellular metabolism to improve cancer therapeutics
Author / Creator:Zhao, Y ; Butler, E B ; Tan, M
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2013-03, Vol.4 (3), p.e532-e532
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Hypoxia‐inducible hexokinase‐2 enhances anti‐apoptotic function via activating autophagy in multiple myeloma
Author / Creator:Ikeda, Sho ; Abe, Fumito ; Matsuda, Yuka ; Kitadate, Akihiro ; Takahashi, Naoto ; Tagawa, Hiroyuki
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2020-11, Vol.111 (11), p.4088-4101
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Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect
Author / Creator:Lu, Chung-Ling ; Qin, Lili ; Liu, Hsin-Chen ; Candas, Demet ; Fan, Ming ; Li, Jian Jian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0121046-e0121046
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TCA-phospholipid-glycolysis targeted triple therapy effectively suppresses ATP production and tumor growth in glioblastoma
Author / Creator:Yang, Shixue ; Zhao, Jixing ; Cui, Xiaoteng ; Zhan, Qi ; Yi, Kaikai ; Wang, Qixue ; Xiao, Menglin ; Tan, Yanli ; Hong, Biao ; Fang, Chuan ; Kang, Chunsheng
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2022-01, Vol.12 (16), p.7032-7050
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Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2
Author / Creator:Li, Wei ; Zheng, Mengzhu ; Wu, Shuangping ; Gao, Suyu ; Yang, Mei ; Li, Zhimei ; Min, Qiuxia ; Sun, Weiguang ; Chen, Lixia ; Xiang, Guangya ; Li, Hua
Publisher:England: BioMed Central
Journal title:Journal of experimental & clinical cancer research, 2017-04, Vol.36 (1), p.58-12, Article 58
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Glucose transporter 2‑transported glucosamine inhibits glycolysis in cancer cell lines through competition with glucose for hexokinase II
Author / Creator:Park, Se ; Song, Ki-Hoon ; Kang, Ju-Hee ; Oh, Seung
Publisher:Greece
Journal title:Oncology reports, 2025-06, Vol.53 (6), p.1-17
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Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis
Author / Creator:Song, Guanhua ; Lu, Qiqi ; Fan, Hua ; Zhang, Xiumei ; Ge, Luna ; Tian, Ruisong ; Wang, Shiguan ; Feng, Tingting ; Pan, Jihong ; Feng, Jingjing ; Xiao, Yabo ; Yi, Xin ; Ren, Ningxin ; Wang, Lin
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2019-04, Vol.21 (1), p.87-87, Article 87
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Hexokinase 2 Suppression Alleviates the Catabolic Properties in Osteoarthritis via HMGA2 and Contributes to Pulsed Electromagnetic Field-mediated Cartilage Protection
Author / Creator:Bao, Chuncha ; Zhu, Siyi ; Pang, Dejiang ; Yang, Ming ; Huang, Jiapeng ; Wang, Fengsheng ; Hou, Yue ; Wang, Xiangxiu ; Feng, Yuan ; Yang, Haolun ; Jiang, Junliang ; He, Jing ; He, Chengqi
Publisher:Australia: Ivyspring International Publisher
Journal title:International journal of biological sciences, 2025-01, Vol.21 (4), p.1459-1477
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Novel mitochondrion‐targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1‐mediating mitophagy in HCC
Author / Creator:Li, Mengmeng ; Shao, Jiangjuan ; Guo, Zijian ; Jin, Chun ; Wang, Ling ; Wang, Feixia ; Jia, Yan ; Zhu, Zhenzhu ; Zhang, Ziji ; Zhang, Feng ; Zheng, Shizhong ; Wang, Xiaoyong
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-03, Vol.24 (5), p.3091-3107
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Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth
Author / Creator:Liu, Yuan ; Murray-Stewart, Tracy ; Casero, Robert A. ; Kagiampakis, Ioannis ; Jin, Lihua ; Zhang, Jiawen ; Wang, Huihui ; Che, Qi ; Tong, Huan ; Ke, Jieqi ; Jiang, Feizhou ; Wang, Fangyuan ; Wan, Xiaoping
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2017-06, Vol.50 (6), p.2011-2023
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Subcellular Localization of Hexokinases I and II Directs the Metabolic Fate of Glucose
Author / Creator:John, Scott ; Weiss, James N. ; Ribalet, Bernard
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-03, Vol.6 (3), p.e17674-e17674
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Hexokinase 2 is a determinant of neuroblastoma metastasis
Author / Creator:Edry Botzer, Liat ; Maman, Shelly ; Sagi-Assif, Orit ; Meshel, Tsipi ; Nevo, Ido ; Yron, Ilana ; Witz, Isaac P
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2016-03, Vol.114 (7), p.759-766
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Metformin Impairs Glucose Consumption and Survival in Calu-1 Cells by Direct Inhibition of Hexokinase-II
Author / Creator:Salani, Barbara ; Marini, Cecilia ; Rio, Alberto Del ; Ravera, Silvia ; Massollo, Michela ; Orengo, Anna Maria ; Amaro, Adriana ; Passalacqua, Mario ; Maffioli, Sara ; Pfeffer, Ulrich ; Cordera, Renzo ; Maggi, Davide ; Sambuceti, Gianmario
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2013-06, Vol.3 (1), p.2070-2070, Article 2070
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Licochalcone A suppresses hexokinase 2-mediated tumor glycolysis in gastric cancer via downregulation of the Akt signaling pathway
Author / Creator:Wu, Jian ; Zhang, Xingxing ; Wang, Yaohui ; Sun, Qingmin ; Chen, Min ; Liu, Shenlin ; Zou, Xi
Publisher:Greece: Spandidos Publications
Journal title:Oncology reports, 2018-03, Vol.39 (3), p.1181-1190
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Hypothesis: A Novel Neuroprotective Role for Glucose-6-phosphatase (G6PC3) in Brain—To Maintain Energy-Dependent Functions Including Cognitive Processes
Author / Creator:Dienel, Gerald A.
Publisher:New York: Springer US
Journal title:Neurochemical research, 2020-11, Vol.45 (11), p.2529-2552
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Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma
Author / Creator:Crippa, Stefania ; Ancey, Pierre‐Benoit ; Vazquez, Jessica ; Angelino, Paolo ; Rougemont, Anne‐Laure ; Guettier, Catherine ; Zoete, Vincent ; Delorenzi, Mauro ; Michielin, Olivier ; Meylan, Etienne
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2017-11, Vol.9 (11), p.1589-1604
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Showing 1 to 20 of 79 results

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Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

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Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic

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Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis

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Targeting cellular metabolism to improve cancer therapeutics

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Hypoxia‐inducible hexokinase‐2 enhances anti‐apoptotic function via activating autophagy in multiple myeloma

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Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect

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TCA-phospholipid-glycolysis targeted triple therapy effectively suppresses ATP production and tumor growth in glioblastoma

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Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2

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Glucose transporter 2‑transported glucosamine inhibits glycolysis in cancer cell lines through competition with glucose for hexokinase II

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Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis

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Hexokinase 2 Suppression Alleviates the Catabolic Properties in Osteoarthritis via HMGA2 and Contributes to Pulsed Electromagnetic Field-mediated Cartilage Protection

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Novel mitochondrion‐targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1‐mediating mitophagy in HCC

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Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth

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Subcellular Localization of Hexokinases I and II Directs the Metabolic Fate of Glucose

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Hexokinase 2 is a determinant of neuroblastoma metastasis

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Metformin Impairs Glucose Consumption and Survival in Calu-1 Cells by Direct Inhibition of Hexokinase-II

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Licochalcone A suppresses hexokinase 2-mediated tumor glycolysis in gastric cancer via downregulation of the Akt signaling pathway

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Hypothesis: A Novel Neuroprotective Role for Glucose-6-phosphatase (G6PC3) in Brain—To Maintain Energy-Dependent Functions Including Cognitive Processes

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Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

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