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21 results for Hinrichs,+Winfried

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Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors
Author / Creator:Perbandt, Markus ; Werner, Nadine ; Prester, Andreas ; Rohde, Holger ; Aepfelbacher, Martin ; Hinrichs, Winfried ; Betzel, Christian
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-04, Vol.12 (1), p.5510-5510, Article 5510
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The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity
Author / Creator:Werner, Nadine ; Petersen, Katrin ; Vollstedt, Christel ; Garcia, Pablo Perez ; Chow, Jennifer ; Ferrer, Manuel ; Fernandez-Lopez, Laura ; Falke, Sven ; Perbandt, Markus ; Hinrichs, Winfried ; Betzel, Christian ; Streit, Wolfgang R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-06, Vol.11 (1), p.12255-12255, Article 12255
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Structural Basis for (2R,3R)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus
Author / Creator:Palm, Gottfried J. ; Thomsen, Maren ; Berndt, Leona ; Hinrichs, Winfried
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-11, Vol.27 (22), p.7909
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Time-resolved crystallography of boric acid binding to the active site serine of the β-lactamase CTX-M-14 and subsequent 1,2-diol esterification
Author / Creator:Prester, Andreas ; Perbandt, Markus ; Galchenkova, Marina ; Oberthuer, Dominik ; Werner, Nadine ; Henkel, Alessandra ; Maracke, Julia ; Yefanov, Oleksandr ; Hakanpää, Johanna ; Pompidor, Guillaume ; Meyer, Jan ; Chapman, Henry ; Aepfelbacher, Martin ; Hinrichs, Winfried ; Rohde, Holger ; Betzel, Christian
Publisher:London: Nature Publishing Group UK
Journal title:Communications chemistry, 2024-07, Vol.7 (1), p.152-12, Article 152
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The crystal structure of an esterase from the hyperthermophilic microorganism Pyrobaculum calidifontis VA1 explains its enantioselectivity
Author / Creator:Palm, Gottfried J. ; Fernández-Álvaro, Elena ; Bogdanović, Xenia ; Bartsch, Sebastian ; Sczodrok, Jaroslaw ; Singh, Rajesh K. ; Böttcher, Dominique ; Atomi, Haruyuki ; Bornscheuer, Uwe T. ; Hinrichs, Winfried
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Applied microbiology and biotechnology, 2011-08, Vol.91 (4), p.1061-1072
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Structural basis of gene regulation by the tetracycline inducible Tet repressor–operator system
Author / Creator:Orth, Peter ; Schnappinger, Dirk ; Hillen, Wolfgang ; Saenger, Wolfram ; Hinrichs, Winfried
Publisher:New York: Nature Publishing Group US
Journal title:Nature Structural Biology, 2000-03, Vol.7 (3), p.215-219
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Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease
Author / Creator:Zühlsdorf, Martin ; Werten, Sebastiaan ; Klupp, Barbara G. ; Palm, Gottfried J. ; Mettenleiter, Thomas C. ; Hinrichs, Winfried
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2015-07, Vol.11 (7), p.e1005045-e1005045
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Correction: Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease
Author / Creator:Zühlsdorf, Martin ; Werten, Sebastiaan ; Klupp, Barbara G. ; Palm, Gottfried J. ; Mettenleiter, Thomas C. ; Hinrichs, Winfried
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2016-03, Vol.12 (3), p.e1005506-e1005506
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Cloning, functional expression, biochemical characterization, and structural analysis of a haloalkane dehalogenase from Plesiocystis pacifica SIR-1
Author / Creator:Hesseler, Martin ; Bogdanović, Xenia ; Hidalgo, Aurelio ; Berenguer, Jose ; Palm, Gottfried J. ; Hinrichs, Winfried ; Bornscheuer, Uwe T.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Applied microbiology and biotechnology, 2011-08, Vol.91 (4), p.1049-1060
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Blocking tetracycline destruction
Author / Creator:Petkovic, Sonja ; Hinrichs, Winfried
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2017-07, Vol.13 (7), p.694-695
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Structure of the Tet Repressor-Tetracycline Complex and Regulation of Antibiotic Resistance
Author / Creator:Hinrichs, Winfried ; Kisker, Caroline ; Düvel, Martina ; Müller, Alexander ; Tovar, Karlheinz ; Hillen, Wolfgang ; Saenger, Wolfram
Publisher:Washington, DC: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 1994-04, Vol.264 (5157), p.418-420
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Antibiotic resistance: Blocking tetracycline destruction
Author / Creator:Petkovic, Sonja ; Hinrichs, Winfried
Publisher:United States: Nature Publishing Group
Journal title:Nature chemical biology, 2017-07, Vol.13 (7), p.694-695
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Three-dimensional structure of system I of photosynthesis at 6 Å resolution
Author / Creator:Krauss, Norbert ; Hinrichs, Winfried ; Witt, Ingrid ; Fromme, Petra ; Pritzkow, Wolfgang ; Dauter, Zbigniew ; Betzel, Christian ; Wilson, Keith S. ; Witt, Horst T. ; Saenger, Wolfram
Publisher:London: Nature Publishing
Journal title:Nature (London), 1993, Vol.361 (6410), p.326-331
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Structural Basis for -Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of IEubacterium ramulus/I
Author / Creator:Palm, Gottfried J ; Thomsen, Maren ; Berndt, Leona ; Hinrichs, Winfried
Publisher:MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-11, Vol.27 (22)
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SARS-CoV-2 Mpro responds to oxidation by forming disulfide and NOS/SONOS bonds
Author / Creator:Reinke, Patrick Y. A. ; Schubert, Robin ; Oberthür, Dominik ; Galchenkova, Marina ; Rahmani Mashhour, Aida ; Günther, Sebastian ; Chretien, Anaïs ; Round, Adam ; Seychell, Brandon Charles ; Norton-Baker, Brenna ; Kim, Chan ; Schmidt, Christina ; Koua, Faisal H. M. ; Tolstikova, Alexandra ; Ewert, Wiebke ; Peña Murillo, Gisel Esperanza ; Mills, Grant ; Kirkwood, Henry ; Brognaro, Hévila ; Han, Huijong ; Koliyadu, Jayanath ; Schulz, Joachim ; Bielecki, Johan ; Lieske, Julia ; Maracke, Julia ; Knoska, Juraj ; Lorenzen, Kristina ; Brings, Lea ; Sikorski, Marcin ; Kloos, Marco ; Vakili, Mohammad ; Vagovic, Patrik ; Middendorf, Philipp ; de Wijn, Raphael ; Bean, Richard ; Letrun, Romain ; Han, Seonghyun ; Falke, Sven ; Geng, Tian ; Sato, Tokushi ; Srinivasan, Vasundara ; Kim, Yoonhee ; Yefanov, Oleksandr M. ; Gelisio, Luca ; Beck, Tobias ; Doré, Andrew S. ; Mancuso, Adrian P. ; Betzel, Christian ; Bajt, Saša ; Redecke, Lars ; Chapman, Henry N. ; Meents, Alke ; Turk, Dušan ; Hinrichs, Winfried ; Lane, Thomas J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-05, Vol.15 (1), p.3827-3827, Article 3827
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A Quantitative Real-Time RT-PCR Assay for the Detection of Venezuelan equine encephalitis virus Utilizing a Universal Alphavirus Control RNA
Author / Creator:Hinrichs, Winfried ; Keller, Markus ; Eiden, Martin ; Vina-Rodriguez, Ariel ; Groschup, Martin H.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2016-01, Vol.2016 (2016), p.1-7
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Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease: e1005045
Author / Creator:Zühlsdorf, Martin ; Werten, Sebastiaan ; Klupp, Barbara G ; Palm, Gottfried J ; Mettenleiter, Thomas C ; Hinrichs, Winfried
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2015-07, Vol.11 (7)
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Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections
Author / Creator:Reinke, Patrick Y. A. ; de Souza, Edmarcia Elisa ; Günther, Sebastian ; Falke, Sven ; Lieske, Julia ; Ewert, Wiebke ; Loboda, Jure ; Herrmann, Alexander ; Rahmani Mashhour, Aida ; Karničar, Katarina ; Usenik, Aleksandra ; Lindič, Nataša ; Sekirnik, Andreja ; Botosso, Viviane Fongaro ; Santelli, Gláucia Maria Machado ; Kapronezai, Josana ; de Araújo, Marcelo Valdemir ; Silva-Pereira, Taiana Tainá ; Filho, Antônio Francisco de Souza ; Tavares, Mariana Silva ; Flórez-Álvarez, Lizdany ; de Oliveira, Danielle Bruna Leal ; Durigon, Edison Luiz ; Giaretta, Paula Roberta ; Heinemann, Marcos Bryan ; Hauser, Maurice ; Seychell, Brandon ; Böhler, Hendrik ; Rut, Wioletta ; Drag, Marcin ; Beck, Tobias ; Cox, Russell ; Chapman, Henry N. ; Betzel, Christian ; Brehm, Wolfgang ; Hinrichs, Winfried ; Ebert, Gregor ; Latham, Sharissa L. ; Guimarães, Ana Marcia de Sá ; Turk, Dusan ; Wrenger, Carsten ; Meents, Alke
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2023-10, Vol.6 (1), p.1058-1058, Article 1058
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SARS-CoV-2 M pro responds to oxidation by forming disulfide and NOS/SONOS bonds
Author / Creator:Reinke, Patrick Y A ; Schubert, Robin ; Oberthür, Dominik ; Galchenkova, Marina ; Rahmani Mashhour, Aida ; Günther, Sebastian ; Chretien, Anaïs ; Round, Adam ; Seychell, Brandon Charles ; Norton-Baker, Brenna ; Kim, Chan ; Schmidt, Christina ; Koua, Faisal H M ; Tolstikova, Alexandra ; Ewert, Wiebke ; Peña Murillo, Gisel Esperanza ; Mills, Grant ; Kirkwood, Henry ; Brognaro, Hévila ; Han, Huijong ; Koliyadu, Jayanath ; Schulz, Joachim ; Bielecki, Johan ; Lieske, Julia ; Maracke, Julia ; Knoska, Juraj ; Lorenzen, Kristina ; Brings, Lea ; Sikorski, Marcin ; Kloos, Marco ; Vakili, Mohammad ; Vagovic, Patrik ; Middendorf, Philipp ; de Wijn, Raphael ; Bean, Richard ; Letrun, Romain ; Han, Seonghyun ; Falke, Sven ; Geng, Tian ; Sato, Tokushi ; Srinivasan, Vasundara ; Kim, Yoonhee ; Yefanov, Oleksandr M ; Gelisio, Luca ; Beck, Tobias ; Doré, Andrew S ; Mancuso, Adrian P ; Betzel, Christian ; Bajt, Saša ; Redecke, Lars ; Chapman, Henry N ; Meents, Alke ; Turk, Dušan ; Hinrichs, Winfried ; Lane, Thomas J
Publisher:England
Journal title:Nature communications, 2024-05, Vol.15 (1), p.3827
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SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design
Author / Creator:Srinivasan, Vasundara ; Brognaro, Hevila ; Prince Rajaiah Prabhu ; De Souza, Edmarci Elisa ; Guenther, Sebastian ; Reinke, Patrick Y A ; Lane, Thomas J ; Ginn, Helen ; Han, Huijong ; Ewert, Wiebke ; Sprenger, Janina ; Koua, Faisal H M ; Falke, Sven ; Werner, Nadine ; Andaleeb, Hina ; Ullah, Najeeb ; Bruno Alves Franca ; Wang, Mengying ; Angelica Luana C Barra ; Perbandt, Markus ; Schwinzer, Martin ; Schmidt, Christina ; Brings, Lea ; Lorenzen, Kristina ; Schubert, Robin ; Rafael Rahal Guaragna Machado ; Candido, Erika Donizette ; Danielle Bruna Leal Oliveira ; Durigon, Edison Luiz ; Yefanov, Oleksandr ; Lieske, Julia ; Gelisio, Luca ; Domaracky, Martin ; Middendorf, Philipp ; Groessler, Michael ; Trost, Fabian ; Galchenkova, Marina ; Saouane, Sofiane ; Hakanpaeae, Johanna ; Wolf, Markus ; Turk, Dusan ; Pearson, Arwen R ; Chapman, Henry N ; Hinrichs, Winfried ; Wrenger, Carsten ; Meents, Alke ; Betzel, Christian
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-11
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Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors

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The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity

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Structural Basis for (2R,3R)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus

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Time-resolved crystallography of boric acid binding to the active site serine of the β-lactamase CTX-M-14 and subsequent 1,2-diol esterification

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The crystal structure of an esterase from the hyperthermophilic microorganism Pyrobaculum calidifontis VA1 explains its enantioselectivity

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Structural basis of gene regulation by the tetracycline inducible Tet repressor–operator system

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Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease

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Correction: Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease

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Cloning, functional expression, biochemical characterization, and structural analysis of a haloalkane dehalogenase from Plesiocystis pacifica SIR-1

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Blocking tetracycline destruction

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Structure of the Tet Repressor-Tetracycline Complex and Regulation of Antibiotic Resistance

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Antibiotic resistance: Blocking tetracycline destruction

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Three-dimensional structure of system I of photosynthesis at 6 Å resolution

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Structural Basis for -Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of IEubacterium ramulus/I

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SARS-CoV-2 Mpro responds to oxidation by forming disulfide and NOS/SONOS bonds

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A Quantitative Real-Time RT-PCR Assay for the Detection of Venezuelan equine encephalitis virus Utilizing a Universal Alphavirus Control RNA

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Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease: e1005045

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Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections

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SARS-CoV-2 M pro responds to oxidation by forming disulfide and NOS/SONOS bonds

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SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design

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