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ArticlesPeer ReviewedFull Text
The importance of 24-h metabolism in obesity-related metabolic disorders: opportunities for timed interventions
Author / Creator:Andriessen, Charlotte ; Schrauwen, Patrick ; Hoeks, Joris
Publisher:London: Nature Publishing Group UK
Journal title:International Journal of Obesity, 2021-03, Vol.45 (3), p.479-490
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Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity
Author / Creator:Houzelle, Alexandre ; Jörgensen, Johanna A. ; Schaart, Gert ; Daemen, Sabine ; van Polanen, Nynke ; Fealy, Ciarán E. ; Hesselink, Matthijs K. C. ; Schrauwen, Patrick ; Hoeks, Joris
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2021-02, Vol.64 (2), p.424-436
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Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
Author / Creator:van der Lans, Anouk A J J ; Hoeks, Joris ; Brans, Boudewijn ; Vijgen, Guy H E J ; Visser, Mariëlle G W ; Vosselman, Maarten J ; Hansen, Jan ; Jörgensen, Johanna A ; Wu, Jun ; Mottaghy, Felix M ; Schrauwen, Patrick ; van Marken Lichtenbelt, Wouter D
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-08, Vol.123 (8), p.3395-3403
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Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle
Author / Creator:Wefers, Jakob ; van Moorsel, Dirk ; Hansen, Jan ; Connell, Niels J. ; Havekes, Bas ; Hoeks, Joris ; van Marken Lichtenbelt, Wouter D. ; Duez, Hélène ; Phielix, Esther ; Kalsbeek, Andries ; Boekschoten, Mark V. ; Hooiveld, Guido J. ; Hesselink, Matthijs K. C. ; Kersten, Sander ; Staels, Bart ; Scheer, Frank A. J. L. ; Schrauwen, Patrick
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7789-7794
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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes
Author / Creator:Vanweert, Froukje ; Neinast, Michael ; Tapia, Edmundo Erazo ; van de Weijer, Tineke ; Hoeks, Joris ; Schrauwen-Hinderling, Vera B. ; Blair, Megan C. ; Bornstein, Marc R. ; Hesselink, Matthijs K. C. ; Schrauwen, Patrick ; Arany, Zoltan ; Phielix, Esther
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-06, Vol.13 (1), p.3508-3508, Article 3508
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Metabolic responses to mild cold acclimation in type 2 diabetes patients
Author / Creator:Remie, Carlijn M. E. ; Moonen, Michiel P. B. ; Roumans, Kay H. M. ; Nascimento, Emmani B. M. ; Gemmink, Anne ; Havekes, Bas ; Schaart, Gert ; Kornips, Esther ; Joris, Peter J. ; Schrauwen-Hinderling, Vera B. ; Hoeks, Joris ; Kersten, Sander ; Hesselink, Matthijs K. C. ; Phielix, Esther ; Lichtenbelt, Wouter D. van Marken ; Schrauwen, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1516-1516, Article 1516
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The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of day
Author / Creator:Harmsen, Jan-Frieder ; Wefers, Jakob ; Doligkeit, Daniel ; Schlangen, Luc ; Dautzenberg, Bas ; Rense, Pascal ; van Moorsel, Dirk ; Hoeks, Joris ; Moonen-Kornips, Esther ; Gordijn, Marijke C. M. ; van Marken Lichtenbelt, Wouter D. ; Schrauwen, Patrick
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2022-04, Vol.65 (4), p.721-732
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Treatment with a β-2-adrenoceptor agonist stimulates glucose uptake in skeletal muscle and improves glucose homeostasis, insulin resistance and hepatic steatosis in mice with diet-induced obesity
Author / Creator:Kalinovich, Anastasia ; Dehvari, Nodi ; Åslund, Alice ; van Beek, Sten ; Halleskog, Carina ; Olsen, Jessica ; Forsberg, Elisabete ; Zacharewicz, Evelyn ; Schaart, Gert ; Rinde, Mia ; Sandström, Anna ; Berlin, Roger ; Östenson, Claes-Göran ; Hoeks, Joris ; Bengtsson, Tore
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2020-08, Vol.63 (8), p.1603-1615
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Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance
Author / Creator:Hanssen, Mark J. W. ; Wierts, Roel ; Hoeks, Joris ; Gemmink, Anne ; Brans, Boudewijn ; Mottaghy, Felix M. ; Schrauwen, Patrick ; van Marken Lichtenbelt, Wouter D.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2015-03, Vol.58 (3), p.586-595
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ArticlesPeer ReviewedFull Text
Nicotinamide Riboside Enhances In Vitro Beta-adrenergic Brown Adipose Tissue Activity in Humans
Author / Creator:Nascimento, Emmani B M ; Moonen, Michiel P B ; Remie, Carlijn M E ; Gariani, Karim ; Jörgensen, Johanna A ; Schaart, Gert ; Hoeks, Joris ; Auwerx, Johan ; van Marken Lichtenbelt, Wouter D ; Schrauwen, Patrick
Publisher:US: Oxford University Press
Journal title:The journal of clinical endocrinology and metabolism, 2021-05, Vol.106 (5), p.1437-1447
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Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humans
Author / Creator:Mancilla, Rodrigo ; Brouwers, Bram ; Schrauwen‐Hinderling, Vera B. ; Hesselink, Matthijs K. C. ; Hoeks, Joris ; Schrauwen, Patrick
Publisher:United States: John Wiley & Sons, Inc
Journal title:Physiological reports, 2021-01, Vol.8 (24), p.e14669-n/a
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Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women
Author / Creator:Remie, Carlijn M. E. ; Janssens, Georges E. ; Bilet, Lena ; van Weeghel, Michel ; Duvivier, Bernard M. F. M. ; de Wit, Vera H. W. ; Connell, Niels J. ; Jörgensen, Johanna A. ; Schomakers, Bauke V. ; Schrauwen-Hinderling, Vera B. ; Hoeks, Joris ; Hesselink, Matthijs K. C. ; Phielix, Esther ; Houtkooper, Riekelt H. ; Schrauwen, Patrick
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2021-12, Vol.64 (12), p.2817-2828
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ArticlesPeer ReviewedFull Text
Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T
Author / Creator:Mevenkamp, Julian ; Bruls, Yvonne M. H. ; Mancilla, Rodrigo ; Grevendonk, Lotte ; Wildberger, Joachim E. ; Brouwers, Kim ; Hesselink, Matthijs K. C. ; Schrauwen, Patrick ; Hoeks, Joris ; Houtkooper, Riekelt H. ; Buitinga, Mijke ; de Graaf, Robin A. ; Lindeboom, Lucas ; Schrauwen-Hinderling, Vera B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.9159-13, Article 9159
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Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients
Author / Creator:PHIELIX, Esther ; SCHRAUWEN-HINDERLING, Vera B ; SCHRAUWEN, Patrick ; MENSINK, Marco ; LENAERS, Ellen ; MEEX, Ruth ; HOEKS, Joris ; ELINE KOOI, Marianne ; MOONEN-KORNIPS, Esther ; SELS, Jean-Pierre ; HESSELINK, Matthijs K. C
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2008-11, Vol.57 (11), p.2943-2949
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High-Fat Diet-Induced Mitochondrial Biogenesis Is Regulated by Mitochondrial-Derived Reactive Oxygen Species Activation of CaMKII
Author / Creator:JAIN, Swati S ; PAGLIALUNGA, Sabina ; HOLLOWAY, Graham P ; VIGNA, Chris ; LUDZKI, Alison ; HERBST, Eric A ; LALLY, James S ; SCHRAUWEN, Patrick ; HOEKS, Joris ; TUPLING, A. Russ ; BONEN, Arend
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2014-06, Vol.63 (6), p.1907-1913
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Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial
Author / Creator:van Beek, Sten M. M. ; Bruls, Yvonne M. H. ; Vanweert, Froukje ; Fealy, Ciarán E. ; Connell, Niels J. ; Schaart, Gert ; Moonen-Kornips, Esther ; Jörgensen, Johanna A. ; Vaz, Frédéric M. ; Smeets, Ellen T. H. C. ; Joris, Peter J. ; Gemmink, Anne ; Houtkooper, Riekelt H. ; Hesselink, Matthijs K. C. ; Bengtsson, Tore ; Havekes, Bas ; Schrauwen, Patrick ; Hoeks, Joris
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-01, Vol.14 (1), p.173-173, Article 173
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PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans
Author / Creator:de Wit-Verheggen, Vera H. W. ; Schrauwen-Hinderling, Vera B. ; Brouwers, Kim ; Jörgensen, Johanna A. ; Schaart, Gert ; Gemmink, Anne ; Nascimento, Emmani B. M. ; Hesselink, Matthijs K. C. ; Wildberger, Joachim E. ; Segers, Patrique ; Montaigne, David ; Staels, Bart ; Schrauwen, Patrick ; Lindeboom, Lucas ; Hoeks, Joris ; van de Weijer, Tineke
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-05, Vol.13 (1), p.8346-8346, Article 8346
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Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance
Author / Creator:HOEKS, Joris ; VAN HERPEN, Noud A ; MENSINK, Marco ; MOONEN-KORNIPS, Esther ; VAN BEURDEN, Denis ; HESSELINK, Matthijs K. C ; SCHRAUWEN, Patrick
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2010-09, Vol.59 (9), p.2117-2125
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ArticlesPeer ReviewedFull Text
Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection
Author / Creator:Lindeboom, Lucas ; Nabuurs, Christine I ; Hoeks, Joris ; Brouwers, Bram ; Phielix, Esther ; Kooi, M Eline ; Hesselink, Matthijs K C ; Wildberger, Joachim E ; Stevens, Robert D ; Koves, Timothy ; Muoio, Deborah M ; Schrauwen, Patrick ; Schrauwen-Hinderling, Vera B
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4915-4925
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Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers
Author / Creator:Nascimento, Emmani B M ; Hangelbroek, Roland W J ; Hooiveld, Guido J E J ; Hoeks, Joris ; Van Marken Lichtenbelt, Wouter D ; Hesselink, Matthijs H C ; Schrauwen, Patrick ; Kersten, Sander
Publisher:England: BioMed Central Ltd
Journal title:BMC medical genomics, 2020-09, Vol.13 (1), p.124-124, Article 124
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The importance of 24-h metabolism in obesity-related metabolic disorders: opportunities for timed interventions

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Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

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Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

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Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

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Metabolic responses to mild cold acclimation in type 2 diabetes patients

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The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of day

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Treatment with a β-2-adrenoceptor agonist stimulates glucose uptake in skeletal muscle and improves glucose homeostasis, insulin resistance and hepatic steatosis in mice with diet-induced obesity

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Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance

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Nicotinamide Riboside Enhances In Vitro Beta-adrenergic Brown Adipose Tissue Activity in Humans

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Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humans

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Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women

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Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T

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Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

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High-Fat Diet-Induced Mitochondrial Biogenesis Is Regulated by Mitochondrial-Derived Reactive Oxygen Species Activation of CaMKII

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Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial

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PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans

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Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

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Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

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Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers

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