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ArticlesPeer ReviewedFull Text
Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporation
Author / Creator:Xu, Xiaoyun ; Gao, Dongbing ; Wang, Ping ; Chen, Jian ; Ruan, Jinxue ; Xu, Jie ; Xia, Xiaofeng
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-08, Vol.8 (1), p.11649-11, Article 11649
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Homology-directed gene-editing approaches for hematopoietic stem and progenitor cell gene therapy
Author / Creator:Azhagiri, Manoj Kumar K. ; Babu, Prathibha ; Venkatesan, Vigneshwaran ; Thangavel, Saravanabhavan
Publisher:London: BioMed Central Ltd
Journal title:Stem cell research & therapy, 2021-09, Vol.12 (1), p.1-500, Article 500
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ArticlesPeer ReviewedFull Text
The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events
Author / Creator:Janssen, Josephine M. ; Chen, Xiaoyu ; Liu, Jin ; Gonçalves, Manuel A.F.V.
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2019-06, Vol.16, p.141-154
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The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balanc...
Author / Creator:Josephine M. Janssen ; Xiaoyu Chen ; Jin Liu ; Manuel A.F.V. Gonçalves
Publisher:Elsevier
Journal title:Molecular therapy. Nucleic acids, 2019-06, Vol.16, p.141-154
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ArticlesPeer ReviewedFull Text
Activated PI3K delta syndrome 1 mutations cause neutrophilia in zebrafish larvae
Author / Creator:Elworthy, Stone ; Rutherford, Holly A. ; Prajsnar, Tomasz K. ; Hamilton, Noémie M. ; Vogt, Katja ; Renshaw, Stephen A. ; Condliffe, Alison M.
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2023-03, Vol.16 (3)
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ArticlesPeer ReviewedFull Text
Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies
Author / Creator:Chandraprabha, Prathibha Babu ; Azhagiri, Manoj Kumar K. ; Venkatesan, Vigneshwaran ; Magis, Wendy ; Prasad, Kirti ; Suresh, Sevanthy ; Pai, Aswin Anand ; Marepally, Srujan ; Srivastava, Alok ; Mohankumar, Kumarasamypet Murugesan ; Martin, David I. K. ; Thangavel, Saravanabhavan
Publisher:England: BioMed Central
Journal title:Stem cell research & therapy, 2024-12, Vol.15 (1), p.504-19, Article 504
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ArticlesFull Text
Reports on Stem Cell Research Findings from University of Michigan Provide New Insights (Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporat...
Publisher:NewsRX LLC
Journal title:Stem cell week, 2018-08, p.72
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Newsletter articlesFull Text
New Gene Editing Findings from Leiden University Medical Center Described (The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing E...
Publisher:NewsRX LLC
Journal title:Biotech Week, 2019, p.303
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ArticlesPeer ReviewedFull Text
Flexible TAM requirement of TnpB enables efficient single-nucleotide editing with expanded targeting scope
Author / Creator:Feng, Xu ; Xu, Ruyi ; Liao, Jianglan ; Zhao, Jingyu ; Zhang, Baochang ; Xu, Xiaoxiao ; Zhao, Pengpeng ; Wang, Xiaoning ; Yao, Jianyun ; Wang, Pengxia ; Wang, Xiaoxue ; Han, Wenyuan ; She, Qunxin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-04, Vol.15 (1), p.3464-14, Article 3464
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ArticlesPeer ReviewedFull Text
Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells
Author / Creator:Hale, Malika ; Mesojednik, Taylor ; Romano Ibarra, Guillermo S. ; Sahni, Jaya ; Bernard, Alison ; Sommer, Karen ; Scharenberg, Andrew M. ; Rawlings, David J. ; Wagner, Thor A.
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-03, Vol.25 (3), p.570-579
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ArticlesPeer ReviewedFull Text
Cas9/gRNA targeted excision of cystic fibrosis-causing deep-intronic splicing mutations restores normal splicing of CFTR mRNA
Author / Creator:Sanz, David J. ; Hollywood, Jennifer A. ; Scallan, Martina F. ; Harrison, Patrick T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-09, Vol.12 (9), p.e0184009
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ArticlesPeer ReviewedFull Text
In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting
Author / Creator:Chen, Xiaoyu ; Janssen, Josephine M. ; Liu, Jin ; Maggio, Ignazio ; ‘t Jong, Anke E. J. ; Mikkers, Harald M.M. ; Gonçalves, Manuel A. F. V.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.657-15, Article 657
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ArticlesPeer ReviewedFull Text
Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for [beta]-hemoglobinopathies
Author / Creator:Chandraprabha, Prathibha Babu ; Azhagiri, Manoj Kumar K ; Venkatesan, Vigneshwaran ; Magis, Wendy ; Prasad, Kirti ; Suresh, Sevanthy ; Pai, Aswin Anand ; Marepally, Srujan ; Srivastava, Alok ; Mohankumar, Kumarasamypet Murugesan ; Martin, David I. K ; Thangavel, Saravanabhavan
Publisher:BioMed Central Ltd
Journal title:Stem cell research & therapy, 2024-12, Vol.15 (1)
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ArticlesPeer ReviewedFull Text
Advances and Obstacles in Homology-Mediated Gene Editing of Hematopoietic Stem Cells
Author / Creator:Salisbury-Ruf, Christi T. ; Larochelle, Andre
Publisher:Switzerland: MDPI AG
Journal title:Journal of clinical medicine, 2021-02, Vol.10 (3), p.513
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Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporation

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Homology-directed gene-editing approaches for hematopoietic stem and progenitor cell gene therapy

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The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events

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The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balanc...

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Activated PI3K delta syndrome 1 mutations cause neutrophilia in zebrafish larvae

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Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies

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Reports on Stem Cell Research Findings from University of Michigan Provide New Insights (Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporat...

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New Gene Editing Findings from Leiden University Medical Center Described (The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing E...

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Flexible TAM requirement of TnpB enables efficient single-nucleotide editing with expanded targeting scope

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Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells

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Cas9/gRNA targeted excision of cystic fibrosis-causing deep-intronic splicing mutations restores normal splicing of CFTR mRNA

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In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting

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Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for [beta]-hemoglobinopathies

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Advances and Obstacles in Homology-Mediated Gene Editing of Hematopoietic Stem Cells

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