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ArticlesPeer ReviewedFull Text
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
Author / Creator:Zhu, Jiajun ; Sammons, Morgan A. ; Donahue, Greg ; Dou, Zhixun ; Vedadi, Masoud ; Getlik, Matthäus ; Barsyte-Lovejoy, Dalia ; Al-awar, Rima ; Katona, Bryson W. ; Shilatifard, Ali ; Huang, Jing ; Hua, Xianxin ; Arrowsmith, Cheryl H. ; Berger, Shelley L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-09, Vol.525 (7568), p.206-211
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Newsletter articlesFull Text
Endocrine Research; Link between inherited endocrine tumor syndrome and much-studied cell pathway
Publisher:Atlanta: NewsRx
Journal title:Obesity, Fitness & Wellness Week, 2013, p.1141
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The same pocket in menin binds both MLL and JUND but has opposite effects on transcription
Author / Creator:Huang, Jing ; Gurung, Buddha ; Wan, Bingbing ; Matkar, Smita ; Veniaminova, Natalia A. ; Wan, Ke ; Merchant, Juanita L. ; Hua, Xianxin ; Lei, Ming
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-02, Vol.482 (7386), p.542-546
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Newsletter articlesFull Text
Neuroendocrine Cancer; Scientists awarded carcinoid tumor and pancreatic neuroendocrine tumor research grants
Publisher:Atlanta: NewsRx
Journal title:Obesity, Fitness & Wellness Week, 2011, p.1568
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ArticlesPeer ReviewedFull Text
CAR T cells targeting CD13 controllably induce eradication of acute myeloid leukemia with a single domain antibody switch
Author / Creator:He, Xin ; Feng, Zijie ; Ma, Jian ; Zhang, Xuyao ; Ling, Sunbin ; Cao, Yan ; Xing, Bowen ; Wu, Yuan ; Wang, Lei ; Katona, Bryson W. ; June, Carl H. ; Hua, Xianxin
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2021-11, Vol.35 (11), p.3309-3313
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Newsletter articlesFull Text
Diabetes Research; Mutation in tumor suppressor gene causes pancreatic islet cells to reproduce
Publisher:Atlanta: NewsRx
Journal title:World Disease Weekly, 2006, p.492
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Newsletter articlesFull Text
Diabetes Research; Mutation in tumor suppressor gene causes pancreatic islet cells to reproduce
Publisher:Atlanta: NewsRx
Journal title:Science Letter, 2006, p.490
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ArticlesPeer ReviewedFull Text
Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation
Author / Creator:Ma, Jian ; Xing, Bowen ; Cao, Yan ; He, Xin ; Bennett, Kate E ; Tong, Chao ; An, Chiying ; Hojnacki, Taylor ; Feng, Zijie ; Deng, Sunbin ; Ling, Sunbin ; Xie, Gengchen ; Wu, Yuan ; Ren, Yue ; Yu, Ming ; Katona, Bryson W ; Li, Hongzhe ; Naji, Ali ; Hua, Xianxin
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2021-05, Vol.13 (5), p.e13524-n/a
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ArticlesPeer ReviewedFull Text
Menin and MLL Cooperatively Regulate Expression of Cyclin-Dependent Kinase Inhibitors
Author / Creator:Milne, Thomas A. ; Hughes, Christina M. ; Lloyd, Ricardo ; Yang, Zhaohai ; Rozenblatt-Rosen, Orit ; Dou, Yali ; Schnepp, Robert W. ; Krankel, Cynthia ; LiVolsi, Virginia A. ; Gibbs, Denise ; Hua, Xianxin ; Roeder, Robert G. ; Meyerson, Matthew ; Hess, Jay L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (3), p.749-754
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ArticlesPeer ReviewedFull Text
Two origins of blastemal progenitors define blastemal regeneration of zebrafish lower jaw
Author / Creator:Wang, Xuelong ; He, Huihui ; Tang, Wenqiao ; Zhang, Xin A ; Hua, Xianxin ; Yan, Jizhou
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e45380-e45380
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ArticlesPeer ReviewedFull Text
Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene
Author / Creator:Yang, Yuqing ; Gurung, Buddha ; Wu, Ting ; Wang, Haoren ; Stoffers, Doris A. ; Hua, Xianxin ; Levine, Arnold J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20358-20363
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ArticlesPeer ReviewedFull Text
The Tumor Suppressor Menin Regulates Hematopoiesis and Myeloid Transformation by Influencing Hox Gene Expression
Author / Creator:Chen, Ya-Xiong ; Yan, Jizhou ; Keeshan, Karen ; Tubbs, Anthony T. ; Wang, Haoren ; Silva, Albert ; Brown, Eric J. ; Hess, Jay L. ; Pear, Warren S. ; Hua, Xianxin
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (4), p.1018-1023
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ArticlesPeer ReviewedFull Text
Squamosamide Derivative FLZ Protects Pancreatic β-Cells from Glucotoxicity by Stimulating Akt-FOXO1 Pathway
Author / Creator:Ma, Xiaosong ; Hua, Xianxin ; Zhang, Longmei ; Kong, Xiangchen
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Journal of diabetes research, 2015-01, Vol.2015 (2015), p.1-9
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ArticlesPeer ReviewedFull Text
Act1, an NF-κ B-activating Protein
Author / Creator:Li, Xiaoxia ; Commane, Mairead ; Nie, Huiqin ; Hua, Xianxin ; Chatterjee-Kishore, Moitreyee ; Wald, David ; Haag, Michael ; Stark, George R.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (19), p.10489-10493
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ArticlesPeer ReviewedFull Text
Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cells
Author / Creator:Yan, Jizhou ; Chen, Ya-Xiong ; Desmond, Angela ; Silva, Albert ; Yang, Yuqing ; Wang, Haoren ; Hua, Xianxin
Publisher:United States: Public Library of Science
Journal title:PloS one, 2006-12, Vol.1 (1), p.e47-e47
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ArticlesPeer ReviewedFull Text
Specificity in Transforming Growth Factor β -Induced Transcription of the Plasminogen Activator Inhibitor-1 Gene: Interactions of Promoter DNA, Transcription Factor μ E3, and Smad Proteins
Author / Creator:Hua, Xianxin ; Miller, Zachary A. ; Wu, Geng ; Shi, Yigong ; Lodish, Harvey F.
Publisher:National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (23), p.13130-13135
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ArticlesPeer ReviewedFull Text
SREBP-2, a Second Basic-Helix-Loop-Helix-Leucine Zipper Protein that Stimulates Transcription by Binding to a Sterol Regulatory Element
Author / Creator:Hua, Xianxin ; Yokoyama, Chieko ; Wu, Jian ; Briggs, Michael R. ; Brown, Michael S. ; Goldstein, Joseph L. ; Wang, Xiaodong
Publisher:Washington, DC: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1993-12, Vol.90 (24), p.11603-11607
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ArticlesPeer ReviewedFull Text
Discovery of a potential positive allosteric modulator of glucagon-like peptide 1 receptor through virtual screening and experimental study
Author / Creator:Redij, Tejashree ; Ma, Jian ; Li, Zhiyu ; Hua, Xianxin ; Li, Zhijun
Publisher:Cham: Springer International Publishing
Journal title:Journal of computer-aided molecular design, 2019-11, Vol.33 (11), p.973-981
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ArticlesPeer ReviewedFull Text
Fusion proteins of retinoid receptors antagonize TGF-β-induced growth inhibition of lung epithelial cells
Author / Creator:La, Ping ; Morgan, Trish A ; Sykes, Stephen M ; Mao, Hua ; Schnepp, Robert W ; Petersen, Clark D ; Hua, Xianxin
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2003-01, Vol.22 (2), p.198-210
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ArticlesPeer ReviewedFull Text
Menin in Cancer
Author / Creator:Majer, Ariana D ; Hua, Xianxin ; Katona, Bryson W
Publisher:Switzerland: MDPI AG
Journal title:Genes, 2024-09, Vol.15 (9), p.1231
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Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

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Endocrine Research; Link between inherited endocrine tumor syndrome and much-studied cell pathway

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The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

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Neuroendocrine Cancer; Scientists awarded carcinoid tumor and pancreatic neuroendocrine tumor research grants

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CAR T cells targeting CD13 controllably induce eradication of acute myeloid leukemia with a single domain antibody switch

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Diabetes Research; Mutation in tumor suppressor gene causes pancreatic islet cells to reproduce

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Diabetes Research; Mutation in tumor suppressor gene causes pancreatic islet cells to reproduce

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Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation

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Menin and MLL Cooperatively Regulate Expression of Cyclin-Dependent Kinase Inhibitors

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Two origins of blastemal progenitors define blastemal regeneration of zebrafish lower jaw

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Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene

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The Tumor Suppressor Menin Regulates Hematopoiesis and Myeloid Transformation by Influencing Hox Gene Expression

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Squamosamide Derivative FLZ Protects Pancreatic β-Cells from Glucotoxicity by Stimulating Akt-FOXO1 Pathway

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Act1, an NF-κ B-activating Protein

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Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cells

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Specificity in Transforming Growth Factor β -Induced Transcription of the Plasminogen Activator Inhibitor-1 Gene: Interactions of Promoter DNA, Transcription Factor μ E3, and Smad Proteins

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SREBP-2, a Second Basic-Helix-Loop-Helix-Leucine Zipper Protein that Stimulates Transcription by Binding to a Sterol Regulatory Element

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Discovery of a potential positive allosteric modulator of glucagon-like peptide 1 receptor through virtual screening and experimental study

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Fusion proteins of retinoid receptors antagonize TGF-β-induced growth inhibition of lung epithelial cells

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Menin in Cancer

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