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Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy
Author / Creator:Wang, Kaiyuan ; Zhang, Xuanbo ; Ye, Hao ; Wang, Xia ; Fan, Zhijin ; Lu, Qi ; Li, Songhao ; Zhao, Jian ; Zheng, Shunzhe ; He, Zhonggui ; Ni, Qianqian ; Chen, Xiaoyuan ; Sun, Jin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-10, Vol.14 (1), p.6748-6748, Article 6748
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OP0120 IDENTIFICATION OF EARLY RISK FACTORS IN A NOVEL PREDICTION MODEL FOR ACPA POSITIVE RA
Author / Creator:Cîrciumaru, A. ; Kisten, Y. ; Hansson, M. ; Mathsson-Alm, L. ; Joshua, V. ; Wähämaa, H. ; Loberg Haarhaus, M. ; Lindqvist, J. ; Guozhong, F. ; Vivar Pomiano, N. ; Rezaei, H. ; Af Klint, E. ; Antovic, A. ; Réthi, B. ; Catrina, A. ; Hensvold, A.
Publisher:Kidlington: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2023-06, Vol.82 (Suppl 1), p.78-79
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Trans-endocytosis of intact IL-15Rα–IL-15 complex from presenting cells into NK cells favors signaling for proliferation
Author / Creator:Anton, Olga M. ; Peterson, Mary E. ; Hollander, Michael J. ; Dorward, David W. ; Arora, Gunjan ; Traba, Javier ; Rajagopalan, Sumati ; Snapp, Erik L. ; Garcia, K. Christopher ; Waldmann, Thomas A. ; Long, Eric O.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (1), p.522-531
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IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development
Author / Creator:O’Leary, Mary F. ; Wallace, Graham R. ; Bennett, Andrew J. ; Tsintzas, Kostas ; Jones, Simon W.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-10, Vol.7 (1), p.12997-11, Article 12997
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IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells
Author / Creator:Van der Meer, J. M. R. ; Maas, R. J. A. ; Guldevall, K. ; Klarenaar, K. ; de Jonge, P. K. J. D. ; Evert, J. S. Hoogstad-van ; van der Waart, A. B. ; Cany, J. ; Safrit, J. T. ; Lee, J. H. ; Wagena, E. ; Friedl, P. ; Önfelt, B. ; Massuger, L. F. ; Schaap, N. P. M. ; Jansen, J. H. ; Hobo, W. ; Dolstra, H.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology and Immunotherapy, 2021-05, Vol.70 (5), p.1305-1321
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An IL-15 superagonist/IL-15Rα fusion complex protects and rescues NK cell-cytotoxic function from TGF-β1-mediated immunosuppression
Author / Creator:Fujii, Rika ; Jochems, Caroline ; Tritsch, Sarah R. ; Wong, Hing C. ; Schlom, Jeffrey ; Hodge, James W.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2018-04, Vol.67 (4), p.675-689
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Plant-derived Pembrolizumab in conjugation with IL-15Rα-IL-15 complex shows effective anti-tumor activity
Author / Creator:Rattanapisit, Kaewta ; Suwanchaikasem, Pipob ; Bulaon, Christine Joy I. ; Guo, Shiying ; Phoolcharoen, Waranyoo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2025-01, Vol.20 (1), p.e0316790
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Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells
Author / Creator:Niogret, Charlène ; Miah, S. M. Shahjahan ; Rota, Giorgia ; Fonta, Nicolas P. ; Wang, Haiping ; Held, Werner ; Birchmeier, Walter ; Sexl, Veronica ; Yang, Wentian ; Vivier, Eric ; Ho, Ping-Chih ; Brossay, Laurent ; Guarda, Greta
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-03, Vol.10 (1), p.1444-14, Article 1444
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Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals
Author / Creator:Tao, Huishan ; Pan, Yun ; Chu, Shuai ; Li, Lei ; Xie, Jinhai ; Wang, Peng ; Zhang, Shimeng ; Reddy, Srija ; Sleasman, John W. ; Zhong, Xiao-Ping
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-04, Vol.12 (1), p.2029-2029, Article 2029
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NKG2D ligands in tumor immunity
Author / Creator:Nausch, N ; Cerwenka, A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2008-10, Vol.27 (45), p.5944-5958
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Heterodimeric IL-15 in Cancer Immunotherapy
Author / Creator:Bergamaschi, Cristina ; Stravokefalou, Vasiliki ; Stellas, Dimitris ; Karaliota, Sevasti ; Felber, Barbara K. ; Pavlakis, George N.
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-02, Vol.13 (4), p.837
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Evaluation of the clinical molecule anti-human-PD-L1/IL-15 KD033 in the human-PD-1/PD-L1-expressing murine model demonstrates PD-L1 targeting of IL-15 in vivo
Author / Creator:Martomo, Stella A. ; Patel, Jeegar
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2023-06, Vol.72 (6), p.1941-1950
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Cytomegalovirus mediates expansion of IL-15– responsive innate-memory cells with SIV killing function
Author / Creator:Méndez-Lagares, Gema ; Chin, Ning ; Chang, W L William ; Lee, Jaewon ; Rosás-Umbert, Míriam ; Kieu, Hung T ; Merriam, David ; Lu, Wenze ; Kim, Sungjin ; Adamson, Lourdes ; Brander, Christian ; Luciw, Paul A ; Barry, Peter A ; Hartigan-O'Connor, Dennis J
Publisher:Ann Arbor: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-08, Vol.131 (15), p.1-15
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Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival
Author / Creator:Hand, Timothy W. ; Cui, Weiguo ; Jung, Yong Woo ; Sefik, Esen ; Joshi, Nikhil S. ; Chandele, Anmol ; Liu, Ying ; Kaech, Susan M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (38), p.16601-16606
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TGFß1 Stimulates Lymphatic Endothelial Cells to Produce IL7 and IL15, Which Act as Chemotactic Factors for Breast Cancer Cells with Mesenchymal Properties
Author / Creator:Giotopoulou, Nikolina ; Shi, Wenyang ; Parniewska, Malgorzata Maria ; Sun, Wenwen ; Fuxe, Jonas
Publisher:New York: Springer US
Journal title:Journal of mammary gland biology and neoplasia, 2023-12, Vol.28 (1), p.25-25, Article 25
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IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes
Author / Creator:James, Olivia J. ; Vandereyken, Maud ; Marchingo, Julia M. ; Singh, Francois ; Bray, Susan E. ; Wilson, Jamie ; Love, Andrew G. ; Swamy, Mahima
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4290-16, Article 4290
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Discovery of a novel IL-15 based protein with improved developability and efficacy for cancer immunotherapy
Author / Creator:Hu, Qiyue ; Ye, Xin ; Qu, Xiangdong ; Cui, Dongbing ; Zhang, Lei ; Xu, Zhibin ; Wan, Hong ; Zhang, Lianshan ; Tao, Weikang
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-05, Vol.8 (1), p.7675-11, Article 7675
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Interleukin-15 after Near-Infrared Photoimmunotherapy (NIR-PIT) Enhances T Cell Response against Syngeneic Mouse Tumors
Author / Creator:Maruoka, Yasuhiro ; Furusawa, Aki ; Okada, Ryuhei ; Inagaki, Fuyuki ; Wakiyama, Hiroaki ; Kato, Takuya ; Nagaya, Tadanobu ; Choyke, Peter L. ; Kobayashi, Hisataka
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2020-09, Vol.12 (9), p.2575
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Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection
Author / Creator:Abeynaike, Shawn A. ; Huynh, Tridu R. ; Mehmood, Abeera ; Kim, Teha ; Frank, Kayla ; Gao, Kefei ; Zalfa, Cristina ; Gandarilla, Angel ; Shultz, Leonard ; Paust, Silke
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-01, Vol.15 (2), p.365
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The functions of IL-23 and IL-2 on driving autoimmune effector T-helper 17 cells into the memory pool in dry eye disease
Author / Creator:Chen, Yihe ; Shao, Chunyi ; Fan, Nai-Wen ; Nakao, Takeshi ; Amouzegar, Afsaneh ; Chauhan, Sunil K. ; Dana, Reza
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2021-01, Vol.14 (1), p.177-186
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Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy

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OP0120 IDENTIFICATION OF EARLY RISK FACTORS IN A NOVEL PREDICTION MODEL FOR ACPA POSITIVE RA

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Trans-endocytosis of intact IL-15Rα–IL-15 complex from presenting cells into NK cells favors signaling for proliferation

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IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development

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IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells

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An IL-15 superagonist/IL-15Rα fusion complex protects and rescues NK cell-cytotoxic function from TGF-β1-mediated immunosuppression

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Plant-derived Pembrolizumab in conjugation with IL-15Rα-IL-15 complex shows effective anti-tumor activity

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Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells

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Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals

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NKG2D ligands in tumor immunity

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Heterodimeric IL-15 in Cancer Immunotherapy

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Evaluation of the clinical molecule anti-human-PD-L1/IL-15 KD033 in the human-PD-1/PD-L1-expressing murine model demonstrates PD-L1 targeting of IL-15 in vivo

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Cytomegalovirus mediates expansion of IL-15– responsive innate-memory cells with SIV killing function

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Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival

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TGFß1 Stimulates Lymphatic Endothelial Cells to Produce IL7 and IL15, Which Act as Chemotactic Factors for Breast Cancer Cells with Mesenchymal Properties

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IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes

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Discovery of a novel IL-15 based protein with improved developability and efficacy for cancer immunotherapy

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Interleukin-15 after Near-Infrared Photoimmunotherapy (NIR-PIT) Enhances T Cell Response against Syngeneic Mouse Tumors

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Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection

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The functions of IL-23 and IL-2 on driving autoimmune effector T-helper 17 cells into the memory pool in dry eye disease

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