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ArticlesPeer ReviewedFull Text
Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells
Author / Creator:Yoshino, Yuki ; Ishioka, Chikashi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-08, Vol.5 (1), p.13249-13249, Article 13249
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Inhibition of IRAK1/4 enhances the antitumor effect of lenvatinib in anaplastic thyroid cancer cells
Author / Creator:Kawamura, Yoshifumi ; Saijo, Ken ; Imai, Hiroo ; Ishioka, Chikashi
Publisher:Tokyo: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-11, Vol.112 (11), p.4711-4721
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Distinct role of CD8 cells and CD4 cells in antitumor immunity triggered by cell apoptosis using a Herpes simplex virus thymidine kinase/ganciclovir system
Author / Creator:Umegaki, Sho ; Shirota, Hidekazu ; Kasahara, Yuki ; Iwasaki, Tomoyuki ; Ishioka, Chikashi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2023-08, Vol.114 (8), p.3076-3086
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Tumor suppressor miR‐193a‐3p enhances efficacy of BRAF/MEK inhibitors in BRAF‐mutated colorectal cancer
Author / Creator:Hiraide, Sakura ; Takahashi, Masanobu ; Yoshida, Yuya ; Yamada, Hideharu ; Komine, Keigo ; Ishioka, Chikashi
Publisher:Tokyo: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-09, Vol.112 (9), p.3856-3870
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ArticlesPeer ReviewedFull Text
IL-4 blockade alters the tumor microenvironment and augments the response to cancer immunotherapy in a mouse model
Author / Creator:Ito, Shuku-ei ; Shirota, Hidekazu ; Kasahara, Yuki ; Saijo, Ken ; Ishioka, Chikashi
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2017-11, Vol.66 (11), p.1485-1496
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ArticlesPeer ReviewedFull Text
Tretinoin synergistically enhances the antitumor effect of combined BRAF, MEK, and EGFR inhibition in BRAFV600E colorectal cancer
Author / Creator:Yoshida, Yuya ; Takahashi, Masanobu ; Taniguchi, Sakura ; Numakura, Ryunosuke ; Komine, Keigo ; Ishioka, Chikashi
Publisher:Tokyo: John Wiley & Sons, Inc
Journal title:Cancer science, 2024-11, Vol.115 (11), p.3740-3754
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ArticlesPeer ReviewedFull Text
Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types
Author / Creator:Sasaki, Keiju ; Takahashi, Shin ; Ouchi, Kota ; Otsuki, Yasufumi ; Wakayama, Shonosuke ; Ishioka, Chikashi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-03, Vol.13 (1), p.4868-4868, Article 4868
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ArticlesPeer ReviewedFull Text
A modified MethyLight assay predicts the clinical outcomes of anti‐epidermal growth factor receptor treatment in metastatic colorectal cancer
Author / Creator:Ouchi, Kota ; Takahashi, Shin ; Okita, Akira ; Sakamoto, Yasuhiro ; Muto, Osamu ; Amagai, Kenji ; Okada, Takaho ; Ohori, Hisatsugu ; Shinozaki, Eiji ; Ishioka, Chikashi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2022-03, Vol.113 (3), p.1057-1068
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ArticlesPeer ReviewedFull Text
Altered gene expression due to aberrant DNA methylation correlates with responsiveness to anti‐EGFR antibody treatment
Author / Creator:Otsuki, Yasufumi ; Ouchi, Kota ; Takahashi, Shin ; Sasaki, Keiju ; Sakamoto, Yasuhiro ; Okita, Akira ; Ishioka, Chikashi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2022-09, Vol.113 (9), p.3221-3233
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ArticlesPeer ReviewedFull Text
LPIN1 downregulation enhances anticancer activity of the novel HDAC/PI3K dual inhibitor FK‐A11
Author / Creator:Imai, Hiroo ; Saijo, Ken ; Chikamatsu, Sonoko ; Kawamura, Yoshifumi ; Ishioka, Chikashi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-02, Vol.112 (2), p.792-802
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ArticlesPeer ReviewedFull Text
The G8 screening tool enhances prognostic value to ECOG performance status in elderly cancer patients: A retrospective, single institutional study
Author / Creator:Takahashi, Masahiro ; Takahashi, Masanobu ; Komine, Keigo ; Yamada, Hideharu ; Kasahara, Yuki ; Chikamatsu, Sonoko ; Okita, Akira ; Ito, Shukuei ; Ouchi, Kota ; Okada, Yoshinari ; Imai, Hiroo ; Saijo, Ken ; Shirota, Hidekazu ; Takahashi, Shin ; Mori, Takahiro ; Shimodaira, Hideki ; Ishioka, Chikashi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-06, Vol.12 (6), p.e0179694-e0179694
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ArticlesPeer ReviewedFull Text
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome
Author / Creator:Abildgaard, Amanda B ; Stein, Amelie ; Nielsen, Sofie V ; Schultz-Knudsen, Katrine ; Papaleo, Elena ; Shrikhande, Amruta ; Hoffmann, Eva R ; Bernstein, Inge ; Gerdes, Anne-Marie ; Takahashi, Masanobu ; Ishioka, Chikashi ; Lindorff-Larsen, Kresten ; Hartmann-Petersen, Rasmus
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2019-11, Vol.8
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ArticlesPeer ReviewedFull Text
Clinical practice guidance for next‐generation sequencing in cancer diagnosis and treatment (Edition 1.0)
Author / Creator:Sunami, Kuniko ; Takahashi, Hideaki ; Tsuchihara, Katsuya ; Takeda, Masayuki ; Suzuki, Tatsuya ; Naito, Yoichi ; Sakai, Kazuko ; Dosaka‐Akita, Hirotoshi ; Ishioka, Chikashi ; Kodera, Yasuhiro ; Muto, Manabu ; Wakai, Toshifumi ; Yamazaki, Kentaro ; Yasui, Wataru ; Bando, Hideaki ; Fujimoto, Yumi ; Fukuoka, Shota ; Harano, Kenichi ; Kawazoe, Akihito ; Kimura, Gen ; Koganemaru, Shigehiro ; Kogawa, Takahiro ; Kotani, Daisuke ; Kuboki, Yasutoshi ; Matsumoto, Hiroshi ; Matsumoto, Shingo ; Mishima, Saori ; Nakamura, Yoshiaki ; Sawada, Kentaro ; Shingaki, Sumito ; Shitara, Kohei ; Umemoto, Kumiko ; Umemura, Shigeki ; Yasuda, Kayo ; Yoshino, Takayuki ; Yamamoto, Noboru ; Nishio, Kazuto
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-09, Vol.109 (9), p.2980-2985
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ArticlesPeer ReviewedFull Text
BRCA1 transports the DNA damage signal for CDDP‐induced centrosome amplification through the centrosomal Aurora A
Author / Creator:Qi, Huicheng ; Kikuchi, Megumi ; Yoshino, Yuki ; Fang, Zhenzhou ; Ohashi, Kazune ; Gotoh, Takato ; Ideta, Ryo ; Ui, Ayako ; Endo, Shino ; Otsuka, Kei ; Shindo, Norihisa ; Gonda, Kohsuke ; Ishioka, Chikashi ; Miki, Yoshio ; Iwabuchi, Tokuro ; Chiba, Natsuko
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2022-12, Vol.113 (12), p.4230-4243
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ArticlesPeer ReviewedFull Text
Efficacy of adding levofloxacin to gemcitabine and nanoparticle-albumin-binding paclitaxel combination therapy in patients with advanced pancreatic cancer: study protocol for a multicenter, randomized...
Author / Creator:Imai, Hiroo ; Sakamoto, Yasuhiro ; Takahashi, Shin ; Shibata, Hiroyuki ; Sato, Atsushi ; Otsuka, Kazunori ; Amagai, Kenji ; Takahashi, Masanobu ; Yamaguchi, Takuhiro ; Ishioka, Chikashi
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2024-02, Vol.24 (1), p.262-262, Article 262
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Guidelines for treatment of renal injury during cancer chemotherapy 2016
Author / Creator:Horie, Shigeo ; Oya, Mototsugu ; Nangaku, Masaomi ; Yasuda, Yoshinari ; Komatsu, Yasuhiro ; Yanagita, Motoko ; Kitagawa, Yuko ; Kuwano, Hiroyuki ; Nishiyama, Hiroyuki ; Ishioka, Chikashi ; Takaishi, Hiromasa ; Shimodaira, Hideki ; Mogi, Akira ; Ando, Yuichi ; Matsumoto, Koji ; Kadowaki, Daisuke ; Muto, Satoru
Publisher:Tokyo: Springer Japan
Journal title:Clinical and experimental nephrology, 2018-02, Vol.22 (1), p.210-244
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Efficacy of modified FOLFOX6 chemotherapy for patients with unresectable pseudomyxoma peritonei
Author / Creator:Hiraide, Sakura ; Komine, Keigo ; Sato, Yuko ; Ouchi, Kota ; Imai, Hiroo ; Saijo, Ken ; Takahashi, Masahiro ; Takahashi, Shin ; Shirota, Hidekazu ; Takahashi, Masanobu ; Ishioka, Chikashi
Publisher:Singapore: Springer Singapore
Journal title:International journal of clinical oncology, 2020-04, Vol.25 (4), p.774-781
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ArticlesPeer ReviewedFull Text
Reply to comments on “Efficacy of modified FOLFOX6 chemotherapy for patients with unresectable pseudomyxoma peritonei”
Author / Creator:Hiraide, Sakura ; Komine, Keigo ; Takahashi, Masanobu ; Ishioka, Chikashi
Publisher:Singapore: Springer Singapore
Journal title:International journal of clinical oncology, 2021-03, Vol.26 (3), p.621-621
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Pretreatment neutrophil–lymphocyte ratio as a prognostic factor in recurrent/metastatic head and neck cancer treated with pembrolizumab
Author / Creator:Kasahara, Yuki ; Saijo, Ken ; Ueta, Reio ; Numakura, Ryunosuke ; Sasaki, Keiju ; Yoshida, Yuya ; Taniguchi, Sakura ; Ouchi, Kota ; Komine, Keigo ; Imai, Hiroo ; Shirota, Hidekazu ; Takahashi, Masanobu ; Ishioka, Chikashi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-11, Vol.14 (1), p.28255-9, Article 28255
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Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 anti...
Author / Creator:Katoh, Yuki ; Yaguchi, Tomonori ; Kubo, Akiko ; Iwata, Takashi ; Morii, Kenji ; Kato, Daiki ; Ohta, Shigeki ; Satomi, Ryosuke ; Yamamoto, Yasuhiro ; Oyamada, Yoshitaka ; Ouchi, Kota ; Takahashi, Shin ; Ishioka, Chikashi ; Matoba, Ryo ; Suematsu, Makoto ; Kawakami, Yutaka
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-07, Vol.10 (7), p.e004616
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Showing 1 to 20 of 136 results

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Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells

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Inhibition of IRAK1/4 enhances the antitumor effect of lenvatinib in anaplastic thyroid cancer cells

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Distinct role of CD8 cells and CD4 cells in antitumor immunity triggered by cell apoptosis using a Herpes simplex virus thymidine kinase/ganciclovir system

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Tumor suppressor miR‐193a‐3p enhances efficacy of BRAF/MEK inhibitors in BRAF‐mutated colorectal cancer

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IL-4 blockade alters the tumor microenvironment and augments the response to cancer immunotherapy in a mouse model

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Tretinoin synergistically enhances the antitumor effect of combined BRAF, MEK, and EGFR inhibition in BRAFV600E colorectal cancer

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Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types

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A modified MethyLight assay predicts the clinical outcomes of anti‐epidermal growth factor receptor treatment in metastatic colorectal cancer

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Altered gene expression due to aberrant DNA methylation correlates with responsiveness to anti‐EGFR antibody treatment

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LPIN1 downregulation enhances anticancer activity of the novel HDAC/PI3K dual inhibitor FK‐A11

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The G8 screening tool enhances prognostic value to ECOG performance status in elderly cancer patients: A retrospective, single institutional study

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Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

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Clinical practice guidance for next‐generation sequencing in cancer diagnosis and treatment (Edition 1.0)

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BRCA1 transports the DNA damage signal for CDDP‐induced centrosome amplification through the centrosomal Aurora A

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Efficacy of adding levofloxacin to gemcitabine and nanoparticle-albumin-binding paclitaxel combination therapy in patients with advanced pancreatic cancer: study protocol for a multicenter, randomized...

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Guidelines for treatment of renal injury during cancer chemotherapy 2016

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Efficacy of modified FOLFOX6 chemotherapy for patients with unresectable pseudomyxoma peritonei

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Reply to comments on “Efficacy of modified FOLFOX6 chemotherapy for patients with unresectable pseudomyxoma peritonei”

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Pretreatment neutrophil–lymphocyte ratio as a prognostic factor in recurrent/metastatic head and neck cancer treated with pembrolizumab

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Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 anti...

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