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CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
Author / Creator:Kurt, Ibrahim C. ; Zhou, Ronghao ; Iyer, Sowmya ; Garcia, Sara P. ; Miller, Bret R. ; Langner, Lukas M. ; Grünewald, Julian ; Joung, J. Keith
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2021-01, Vol.39 (1), p.41-46
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Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
Author / Creator:Grünewald, Julian ; Zhou, Ronghao ; Garcia, Sara P. ; Iyer, Sowmya ; Lareau, Caleb A. ; Aryee, Martin J. ; Joung, J. Keith
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-05, Vol.569 (7756), p.433-437
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GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy
Author / Creator:Kasiewicz, Lisa N. ; Biswas, Souvik ; Beach, Aaron ; Ren, Huilan ; Dutta, Chaitali ; Mazzola, Anne Marie ; Rohde, Ellen ; Chadwick, Alexandra ; Cheng, Christopher ; Garcia, Sara P. ; Iyer, Sowmya ; Matsumoto, Yuri ; Khera, Amit V. ; Musunuru, Kiran ; Kathiresan, Sekar ; Malyala, Padma ; Rajeev, Kallanthottathil G. ; Bellinger, Andrew M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-05, Vol.14 (1), p.2776-10, Article 2776
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Caregiver Experience of Tele-dementia Care for Older Veterans
Author / Creator:Iyer, Sowmya S. ; Ngo, Victoria ; Humber, Marika Blair ; Chen, Peijun ; Pallaki, Muralidhar ; Dolinar, Teresa ; Brodrick, Marisa-Francesca B. ; Gould, Christine E. ; Trivedi, Ranak B.
Publisher:United States: Springer Nature B.V
Journal title:Journal of general internal medicine : JGIM, 2023-10, Vol.38 (13), p.2960-2969
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A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
Author / Creator:Grünewald, Julian ; Zhou, Ronghao ; Lareau, Caleb A. ; Garcia, Sara P. ; Iyer, Sowmya ; Miller, Bret R. ; Langner, Lukas M. ; Hsu, Jonathan Y. ; Aryee, Martin J. ; Joung, J. Keith
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2020-07, Vol.38 (7), p.861-864
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Converting a Geriatrics Clinic to Virtual Visits during COVID-19: A Case Study
Author / Creator:Iyer, Sowmya ; Mehta, Priyanka ; Weith, Joanne ; Hoang-Gia, Dat ; Moore, Janet ; Carlson, Chalise ; Choe, Philip ; Sakai, Erin ; Gould, Christine
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Journal of primary care & community health, 2021, Vol.12, p.21501327211000235
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EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors
Author / Creator:Boulay, Gaylor ; Broye, Liliane C. ; Dong, Rui ; Iyer, Sowmya ; Sanalkumar, Rajendran ; Xing, Yu-Hang ; Buisson, Rémi ; Rengarajan, Shruthi ; Naigles, Beverly ; Duc, Benoît ; Volorio, Angela ; Awad, Mary E. ; Renella, Raffaele ; Chebib, Ivan ; Nielsen, G. Petur ; Choy, Edwin ; Cote, Gregory M. ; Zou, Lee ; Letovanec, Igor ; Stamenkovic, Ivan ; Rivera, Miguel N. ; Riggi, Nicolò
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.7460-17, Article 7460
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A (fire)cloud-based DNA methylation data preprocessing and quality control platform
Author / Creator:Kangeyan, Divy ; Dunford, Andrew ; Iyer, Sowmya ; Stewart, Chip ; Hanna, Megan ; Getz, Gad ; Aryee, Martin J.
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2019-03, Vol.20 (1), p.160-5, Article 160
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High-Throughput Sequencing Analysis of Post-Liver Transplantation HCV E2 Glycoprotein Evolution in the Presence and Absence of Neutralizing Monoclonal Antibody
Author / Creator:Babcock, Gregory J. ; Iyer, Sowmya ; Smith, Heidi L. ; Wang, Yang ; Rowley, Kirk ; Ambrosino, Donna M. ; Zamore, Phillip D. ; Pierce, Brian G. ; Molrine, Deborah C. ; Weng, Zhiping
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-06, Vol.9 (6), p.e100325
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ArticlesPeer ReviewedFull Text
CRISPR DNA base editors with reduced RNA off-target and self-editing activities
Author / Creator:Grünewald, Julian ; Zhou, Ronghao ; Iyer, Sowmya ; Lareau, Caleb A. ; Garcia, Sara P. ; Aryee, Martin J. ; Joung, J. Keith
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2019-09, Vol.37 (9), p.1041-1048
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Experimental comparison of a NACA0021 airfoil in large plunging and surging motions at 90 ◦ angle of attack
Author / Creator:Xu, Guanqun ; Yu, Wei ; Ferreira, Carlos ; Sciacchitano, Andrea ; Iyer, Sowmya
Publisher:Bristol: IOP Publishing
Journal title:Journal of physics. Conference series, 2024-06, Vol.2767 (2), p.22047
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In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
Author / Creator:Musunuru, Kiran ; Chadwick, Alexandra C. ; Mizoguchi, Taiji ; Garcia, Sara P. ; DeNizio, Jamie E. ; Reiss, Caroline W. ; Wang, Kui ; Iyer, Sowmya ; Dutta, Chaitali ; Clendaniel, Victoria ; Amaonye, Michael ; Beach, Aaron ; Berth, Kathleen ; Biswas, Souvik ; Braun, Maurine C. ; Chen, Huei-Mei ; Colace, Thomas V. ; Ganey, John D. ; Gangopadhyay, Soumyashree A. ; Garrity, Ryan ; Kasiewicz, Lisa N. ; Lavoie, Jennifer ; Madsen, James A. ; Matsumoto, Yuri ; Mazzola, Anne Marie ; Nasrullah, Yusuf S. ; Nneji, Joseph ; Ren, Huilan ; Sanjeev, Athul ; Shay, Madeleine ; Stahley, Mary R. ; Fan, Steven H. Y. ; Tam, Ying K. ; Gaudelli, Nicole M. ; Ciaramella, Giuseppe ; Stolz, Leslie E. ; Malyala, Padma ; Cheng, Christopher J. ; Rajeev, Kallanthottathil G. ; Rohde, Ellen ; Bellinger, Andrew M. ; Kathiresan, Sekar
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-05, Vol.593 (7859), p.429-434
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Caregiver Experience of Tele-dementia Care for Older Veterans: Delivering Tele-dementia Care to Older Veterans
Author / Creator:Iyer, Sowmya S. ; Ngo, Victoria ; Humber, Marika Blair ; Chen, Peijun ; Pallaki, Muralidhar ; Dolinar, Teresa ; Brodrick, Marisa-Francesca B. ; Gould, Christine E. ; Trivedi, Ranak B.
Publisher:Cham: Springer International Publishing
Journal title:Journal of general internal medicine : JGIM, 2023-10, Vol.38 (13), p.2960-2969
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Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia
Author / Creator:Oliveira, Mariana L ; Veloso, Alexandra ; Garcia, Elaine G ; Iyer, Sowmya ; Pereira, Clara ; Barreto, Vasco M ; Langenau, David M ; Barata, João T
Publisher:London: Nature Publishing Group
Journal title:Leukemia, 2022-06, Vol.36 (6), p.1533-1540
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Augmenting and directing long-range CRISPR-mediated activation in human cells
Author / Creator:Tak, Y. Esther ; Horng, Joy E. ; Perry, Nicholas T. ; Schultz, Hayley T. ; Iyer, Sowmya ; Yao, Qiuming ; Zou, Luli S. ; Aryee, Martin J. ; Pinello, Luca ; Joung, J. Keith
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2021-09, Vol.18 (9), p.1075-1081
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The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
Author / Creator:Giblin, William ; Bringman-Rodenbarger, Lauren ; Guo, Angela H. ; Kumar, Surinder ; Monovich, Alexander C. ; Mostafa, Ahmed M. ; Skinner, Mary E. ; Azar, Michelle ; Mady, Ahmed S.A. ; Chung, Carolina H. ; Kadambi, Namrata ; Melong, Keith-Allen ; Lee, Ho-Joon ; Zhang, Li ; Sajjakulnukit, Peter ; Trefely, Sophie ; Varner, Erika L. ; Iyer, Sowmya ; Wang, Min ; Wilmott, James S. ; Soyer, H. Peter ; Sturm, Richard A. ; Pritchard, Antonia L. ; Andea, Aleodor A. ; Scolyer, Richard A. ; Stark, Mitchell S. ; Scott, David A. ; Fullen, Douglas R. ; Bosenberg, Marcus W. ; Chandrasekaran, Sriram ; Nikolovska-Coleska, Zaneta ; Verhaegen, Monique E. ; Snyder, Nathaniel W. ; Rivera, Miguel N. ; Osterman, Andrei L. ; Lyssiotis, Costas A. ; Lombard, David B.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-06, Vol.131 (12), p.1-18
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EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma
Author / Creator:Möller, Emely ; Praz, Viviane ; Rajendran, Sanalkumar ; Dong, Rui ; Cauderay, Alexandra ; Xing, Yu-Hang ; Lee, Lukuo ; Fusco, Carlo ; Broye, Liliane C. ; Cironi, Luisa ; Iyer, Sowmya ; Rengarajan, Shruthi ; Awad, Mary E. ; Naigles, Beverly ; Letovanec, Igor ; Ormas, Nicola ; Finzi, Giovanna ; La Rosa, Stefano ; Sessa, Fausto ; Chebib, Ivan ; Petur Nielsen, G. ; Digklia, Antonia ; Spentzos, Dimitrios ; Cote, Gregory M. ; Choy, Edwin ; Aryee, Martin ; Stamenkovic, Ivan ; Boulay, Gaylor ; Rivera, Miguel N. ; Riggi, Nicolò
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.2267-18, Article 2267
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Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia
Author / Creator:Garcia, Elaine G. ; Iyer, Sowmya ; Garcia, Sara P. ; Loontiens, Siebe ; Sadreyev, Ruslan I. ; Speleman, Frank ; Langenau, David M.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2018-08, Vol.32 (8), p.1860-1865
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Molecularly distinct models of zebrafish Myc-induced B cell leukemia
Author / Creator:Borga, Chiara ; Foster, Clay A. ; Iyer, Sowmya ; Garcia, Sara P. ; Langenau, David M. ; Frazer, J. Kimble
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2019-02, Vol.33 (2), p.559-562
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Author Correction: Augmenting and directing long-range CRISPR-mediated activation in human cells
Author / Creator:Tak, Y. Esther ; Horng, Joy E. ; Perry, Nicholas T. ; Schultz, Hayley T. ; Iyer, Sowmya ; Yao, Qiuming ; Zou, Luli S. ; Aryee, Martin J. ; Pinello, Luca ; Joung, J. Keith
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2022-07, Vol.19 (7), p.899-899
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Showing 1 to 20 of 32 results

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CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells

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Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

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GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy

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Caregiver Experience of Tele-dementia Care for Older Veterans

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A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing

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Converting a Geriatrics Clinic to Virtual Visits during COVID-19: A Case Study

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EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors

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A (fire)cloud-based DNA methylation data preprocessing and quality control platform

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High-Throughput Sequencing Analysis of Post-Liver Transplantation HCV E2 Glycoprotein Evolution in the Presence and Absence of Neutralizing Monoclonal Antibody

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CRISPR DNA base editors with reduced RNA off-target and self-editing activities

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Experimental comparison of a NACA0021 airfoil in large plunging and surging motions at 90 ◦ angle of attack

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In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates

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Caregiver Experience of Tele-dementia Care for Older Veterans: Delivering Tele-dementia Care to Older Veterans

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Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia

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Augmenting and directing long-range CRISPR-mediated activation in human cells

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The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics

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EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma

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Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia

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Molecularly distinct models of zebrafish Myc-induced B cell leukemia

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Author Correction: Augmenting and directing long-range CRISPR-mediated activation in human cells

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