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Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy
Author / Creator:Lequeux, Audrey ; Noman, Muhammad Zaeem ; Xiao, Malina ; Van Moer, Kris ; Hasmim, Meriem ; Benoit, Alice ; Bosseler, Manon ; Viry, Elodie ; Arakelian, Tsolere ; Berchem, Guy ; Chouaib, Salem ; Janji, Bassam
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-07, Vol.40 (28), p.4725-4735
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Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner
Author / Creator:Mgrditchian, Takouhie ; Arakelian, Tsolere ; Paggetti, Jérôme ; Noman, Muhammad Zaeem ; Viry, Elodie ; Moussay, Etienne ; Van Moer, Kris ; Kreis, Stephanie ; Guerin, Coralie ; Buart, Stephanie ; Robert, Caroline ; Borg, Christophe ; Vielh, Philippe ; Chouaib, Salem ; Berchem, Guy ; Janji, Bassam
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (44), p.E9271-E9279
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Atypical chemokine receptor 2 expression is directly regulated by hypoxia inducible factor-1 alpha in cancer cells under hypoxia
Author / Creator:Benoit, Alice ; Lequeux, Audrey ; Harter, Phillip ; Berchem, Guy ; Janji, Bassam
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-11, Vol.14 (1), p.26589-9, Article 26589
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Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Author / Creator:Kiweler, Nicole ; Delbrouck, Catherine ; Pozdeev, Vitaly I. ; Neises, Laura ; Soriano-Baguet, Leticia ; Eiden, Kim ; Xian, Feng ; Benzarti, Mohaned ; Haase, Lara ; Koncina, Eric ; Schmoetten, Maryse ; Jaeger, Christian ; Noman, Muhammad Zaeem ; Vazquez, Alexei ; Janji, Bassam ; Dittmar, Gunnar ; Brenner, Dirk ; Letellier, Elisabeth ; Meiser, Johannes
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2699-2699, Article 2699
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Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges
Author / Creator:Noman, Muhammad Zaeem ; Hasmim, Meriem ; Lequeux, Audrey ; Xiao, Malina ; Duhem, Caroline ; Chouaib, Salem ; Berchem, Guy ; Janji, Bassam
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2019-09, Vol.8 (9), p.1083
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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia
Author / Creator:Baginska, Joanna ; Viry, Elodie ; Berchem, Guy ; Poli, Aurélie ; Noman, Muhammad Zaeem ; van Moer, Kris ; Medves, Sandrine ; Zimmer, Jacques ; Oudin, Anaïs ; Niclou, Simone P. ; Bleackley, R. Chris ; Goping, Ing Swie ; Chouaib, Salem ; Janji, Bassam
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (43), p.17450-17455
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Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A
Author / Creator:Abdul Rahim, Siti Aminah ; Dirkse, Anne ; Oudin, Anais ; Schuster, Anne ; Bohler, Jill ; Barthelemy, Vanessa ; Muller, Arnaud ; Vallar, Laurent ; Janji, Bassam ; Golebiewska, Anna ; Niclou, Simone P
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2017-09, Vol.117 (6), p.813-825
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Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2
Author / Creator:Hoffmann, Céline ; Mao, Xianqing ; Brown-Clay, Joshua ; Moreau, Flora ; Al Absi, Antoun ; Wurzer, Hannah ; Sousa, Barbara ; Schmitt, Fernando ; Berchem, Guy ; Janji, Bassam ; Thomas, Clément
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-07, Vol.8 (1), p.10191-14, Article 10191
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Lighting Up the Fire in the Microenvironment of Cold Tumors: A Major Challenge to Improve Cancer Immunotherapy
Author / Creator:Benoit, Alice ; Vogin, Guillaume ; Duhem, Caroline ; Berchem, Guy ; Janji, Bassam
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-07, Vol.12 (13), p.1787
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The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment
Author / Creator:Reynders, Nathan ; Abboud, Dayana ; Baragli, Alessandra ; Noman, Muhammad Zaeem ; Rogister, Bernard ; Niclou, Simone P ; Heveker, Nikolaus ; Janji, Bassam ; Hanson, Julien ; Szpakowska, Martyna ; Chevigné, Andy
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2019-06, Vol.8 (6), p.613
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Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti‐tumor efficacy
Author / Creator:Yu, Yasmin ; Bogdan, Madhumita ; Noman, Muhammad Zaeem ; Parpal, Santiago ; Bartolini, Elisabetta ; Van Moer, Kris ; Kleinendorst, Simone Caroline ; Bilgrav Saether, Kristine ; Trésaugues, Lionel ; Silvander, Camilla ; Lindström, Johan ; Simeon, Jodi ; Timson, Mary Jane ; Al‐Hashimi, Hikmat ; Smith, Bryan D. ; Flynn, Daniel L. ; Alexeyenko, Andrey ; Viklund, Jenny ; Andersson, Martin ; Martinsson, Jessica ; Pokrovskaja Tamm, Katja ; De Milito, Angelo ; Janji, Bassam
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2024-08, Vol.18 (8), p.1904-1922
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The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model
Author / Creator:Sauvage, Delphine ; Bosseler, Manon ; Viry, Elodie ; Kanli, Georgia ; Oudin, Anais ; Berchem, Guy ; Keunen, Olivier ; Janji, Bassam
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-09, Vol.11 (18), p.2783
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Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells
Author / Creator:Aouali, Nassera ; Broukou, Angeliki ; Bosseler, Manon ; Keunen, Olivier ; Schlesser, Vincent ; Janji, Bassam ; Palissot, Valerie ; Stordeur, Philippe ; Berchem, Guy
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0130339-e0130339
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Assessing autophagy in archived tissue or how to capture autophagic flux from a tissue snapshot
Author / Creator:Humbert, Magali ; Morán, María ; de la Cruz-Ojeda, Patricia ; Muntané, Jordi ; Wiedmer, Tabea ; Apostolova, Nadezda ; McKenna, Sharon L. ; Velasco, Guillermo ; Balduini, Walter ; Eckhart, Leopold ; Janji, Bassam ; Marques, Maria Belém Sousa Sampaio ; Ludovico, Paula ; Žerovnik, Eva ; Langer, Rupert ; Perren, Aurel ; Engedal, Nikolai ; Tschan, Mario P.
Publisher:Switzerland: Multidisciplinary Digital Publishing Institute
Journal title:Biology (Basel, Switzerland), 2020-03, Vol.9 (3), p.59
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Rapid tumor development and potent vascularization are independent events in carcinoma producing FGF-1 or FGF-2
Author / Creator:BILLOTTET, Clotilde ; JANJI, Bassam ; THIERY, Jean-Paul ; JOUANNEAU, Jacqueline
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 2002-11, Vol.21 (53), p.8128-8139
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ArticlesPeer ReviewedFull Text
Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-β1 stimulation
Author / Creator:JANJI, B ; MELCHIOR, C ; VALLAR, L ; KIEFFER, N
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 2000-06, Vol.19 (27), p.3069-3077
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CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6
Author / Creator:Chevigné, Andy ; Janji, Bassam ; Meyrath, Max ; Reynders, Nathan ; D'Uonnolo, Giulia ; Uchański, Tomasz ; Xiao, Malina ; Berchem, Guy ; Ollert, Markus ; Kwon, Yong-Jun ; Noman, Muhammad Zaeem ; Szpakowska, Martyna
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-03, Vol.13 (5), p.1054
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Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer
Author / Creator:Xiao, Malina ; Hasmim, Meriem ; Lequeux, Audrey ; Moer, Kris Van ; Tan, Tuan Zea ; Gilles, Christine ; Hollier, Brett G ; Thiery, Jean Paul ; Berchem, Guy ; Janji, Bassam ; Noman, Muhammad Zaeem
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-03, Vol.13 (5), p.1165
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Selection of tumor‑resistant variants following sustained natural killer cell‑mediated immune stress
Author / Creator:Carré, Thibault ; Thiery, Jerome ; Janji, Bassam ; Terry, Stéphane ; Gros, Gwendoline ; Meurice, Guillaume ; Kieda, Claudine ; Olive, Daniel ; Chouaib, Salem
Publisher:Greece: Spandidos Publications
Journal title:Oncology reports, 2021-02, Vol.45 (2), p.582-594
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Carbonic Anhydrase IX: A Renewed Target for Cancer Immunotherapy
Author / Creator:Campos, Najla Santos Pacheco de ; Souza, Bruna Santos ; Silva, Giselle Correia Próspero da ; Porto, Victoria Alves ; Chalbatani, Ghanbar Mahmoodi ; Lagreca, Gabriela ; Janji, Bassam ; Suarez, Eloah Rabello
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2022-03, Vol.14 (6), p.1392
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Showing 1 to 20 of 26 results

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Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy

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Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner

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Atypical chemokine receptor 2 expression is directly regulated by hypoxia inducible factor-1 alpha in cancer cells under hypoxia

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Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis

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Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges

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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

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Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A

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Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2

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Lighting Up the Fire in the Microenvironment of Cold Tumors: A Major Challenge to Improve Cancer Immunotherapy

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The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

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Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti‐tumor efficacy

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The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model

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Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells

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Assessing autophagy in archived tissue or how to capture autophagic flux from a tissue snapshot

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Rapid tumor development and potent vascularization are independent events in carcinoma producing FGF-1 or FGF-2

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Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-β1 stimulation

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CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6

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Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer

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Selection of tumor‑resistant variants following sustained natural killer cell‑mediated immune stress

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Carbonic Anhydrase IX: A Renewed Target for Cancer Immunotherapy

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