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ArticlesPeer ReviewedFull Text
Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions
Author / Creator:Bernardi, Paolo ; Gerle, Christoph ; Halestrap, Andrew P. ; Jonas, Elizabeth A. ; Karch, Jason ; Mnatsakanyan, Nelli ; Pavlov, Evgeny ; Sheu, Shey-Shing ; Soukas, Alexander A.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2023-08, Vol.30 (8), p.1869-1885
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Identifying the components of the elusive mitochondrial permeability transition pore
Author / Creator:Karch, Jason ; Molkentin, Jeffery D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10396-10397
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Genetic lineage tracing defines myofibroblast origin and function in the injured heart
Author / Creator:Kanisicak, Onur ; Khalil, Hadi ; Ivey, Malina J. ; Karch, Jason ; Maliken, Bryan D. ; Correll, Robert N. ; Brody, Matthew J. ; J. Lin, Suh-Chin ; Aronow, Bruce J. ; Tallquist, Michelle D. ; Molkentin, Jeffery D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-07, Vol.7 (1), p.12260-12260, Article 12260
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ArticlesPeer ReviewedFull Text
c-kit+ cells minimally contribute cardiomyocytes to the heart
Author / Creator:van Berlo, Jop H. ; Kanisicak, Onur ; Maillet, Marjorie ; Vagnozzi, Ronald J. ; Karch, Jason ; Lin, Suh-Chin J. ; Middleton, Ryan C. ; Marbán, Eduardo ; Molkentin, Jeffery D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-05, Vol.509 (7500), p.337-341
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Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death
Author / Creator:Karch, Jason ; Kanisicak, Onur ; Brody, Matthew J. ; Sargent, Michelle A. ; Michael, Demetria M. ; Molkentin, Jeffery D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0130520-e0130520
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Misoprostol treatment prevents hypoxia-induced cardiac dysfunction through a 14-3-3 and PKA regulatory motif on Bnip3
Author / Creator:Martens, Matthew D. ; Seshadri, Nivedita ; Nguyen, Lucas ; Chapman, Donald ; Henson, Elizabeth S. ; Xiang, Bo ; Falk, Landon ; Mendoza, Arielys ; Rattan, Sunil ; Field, Jared T. ; Kawalec, Philip ; Gibson, Spencer B. ; Keijzer, Richard ; Saleem, Ayesha ; Hatch, Grant M. ; Doucette, Christine A. ; Karch, Jason M. ; Dolinsky, Vernon W. ; Dixon, Ian M. ; West, Adrian R. ; Rampitsch, Christof ; Gordon, Joseph W.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-11, Vol.12 (12), p.1105-1105, Article 1105
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Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak
Author / Creator:Karch, Jason ; Schips, Tobias G ; Maliken, Bryan D ; Brody, Matthew J ; Sargent, Michelle A ; Kanisicak, Onur ; Molkentin, Jeffery D
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-11, Vol.6
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Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
Author / Creator:Karch, Jason ; Kwong, Jennifer Q ; Burr, Adam R ; Sargent, Michelle A ; Elrod, John W ; Peixoto, Pablo M ; Martinez-Caballero, Sonia ; Osinska, Hanna ; Cheng, Emily H-Y ; Robbins, Jeffrey ; Kinnally, Kathleen W ; Molkentin, Jeffery D
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2013-08, Vol.2, p.e00772-e00772
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Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability
Author / Creator:Schips, Tobias G. ; Vanhoutte, Davy ; Vo, Alexander ; Correll, Robert N. ; Brody, Matthew J. ; Khalil, Hadi ; Karch, Jason ; Tjondrokoesoemo, Andoria ; Sargent, Michelle A. ; Maillet, Marjorie ; Ross, Robert S. ; Molkentin, Jeffery D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.76-15, Article 76
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A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome
Author / Creator:Song, Jia ; Wu, Jiao ; Robichaux, Dexter J. ; Li, Tingting ; Wang, Shuyue ; Arredondo Sancristobal, Maria J. ; Dong, Bingning ; Dobrev, Dobromir ; Karch, Jason ; Thomas, Sandhya S. ; Li, Na
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-01, Vol.13 (2), p.108
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Phosphorylation-Dependent Interactome of Ryanodine Receptor Type 2 in the Heart
Author / Creator:Chiang, David Y. ; Lahiri, Satadru ; Wang, Guoliang ; Karch, Jason ; Wang, Meng C. ; Jung, Sung Y. ; Heck, Albert J. R. ; Scholten, Arjen ; Wehrens, Xander H. T.
Publisher:Basel: MDPI AG
Journal title:Proteomes, 2021-06, Vol.9 (2), p.27
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Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis
Author / Creator:Khalil, Hadi ; Kanisicak, Onur ; Prasad, Vikram ; Correll, Robert N. ; Fu, Xing ; Schips, Tobias ; Vagnozzi, Ronald J. ; Liu, Ruijie ; Huynh, Thanh ; Lee, Se-Jin ; Karch, Jason ; Molkentin, Jeffery D.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-10, Vol.127 (10), p.3770-3783
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Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice
Author / Creator:Elrod, John W. ; Wong, Renee ; Mishra, Shikha ; Vagnozzi, Ronald J. ; Sakthievel, Bhuvana ; Goonasekera, Sanjeewa A. ; Karch, Jason ; Gabel, Scott ; Farber, John ; Force, Thomas ; Heller Brown, Joan ; Murphy, Elizabeth ; Molkentin, Jeffery D.
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2010-10, Vol.120 (10), p.3680-3687
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ArticlesPeer ReviewedFull Text
Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice
Author / Creator:Elrod, John W. ; Wong, Renee ; Mishra, Shikha ; Vagnozzi, Ronald J. ; Sakthievel, Bhuvana ; Goonasekera, Sanjeewa A. ; Karch, Jason ; Gabel, Scott ; Farber, John ; Force, Thomas ; Heller Brown, Joan ; Murphy, Elizabeth ; Molkentin, Jeffery D.
Journal title:The Journal of clinical investigation, 2010-10, Vol.120 (10), p.3680-3687
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ArticlesPeer ReviewedFull Text
Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice
Author / Creator:Elrod, John W ; Wong, Renee ; Mishra, Shikha ; Vagnozzi, Ronald J ; Sakthievel, Bhuvana ; Goonasekera, Sanjeewa A ; Karch, Jason ; Gabel, Scott ; Farber, John ; Force, Thomas ; Brown, Joan Heller ; Murphy, Elizabeth ; Molkentin, Jeffery D
Publisher:United States
Journal title:The Journal of clinical investigation, 2010-10, Vol.120 (10), p.3680-3687
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Irisin: A Promising Target for Ischemia-Reperfusion Injury Therapy
Author / Creator:Wang, Yani ; Liu, Huibin ; Sun, Na ; Li, Jing ; Peng, Xiang ; Jia, Ying ; Karch, Jason ; Yu, Bo ; Wehrens, Xander H. T. ; Tian, Jinwei
Publisher:United States: Hindawi
Journal title:Oxidative medicine and cellular longevity, 2021, Vol.2021 (1), p.5391706
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Fibroblast-specific TGF-[beta]-Smad2/3 signaling underlies cardiac fibrosis
Author / Creator:Khalil, Hadi ; Kanisicak, Onur ; Prasad, Vikram ; Correll, Robert N ; Fu, Xing ; Schips, Tobias ; Vagnozzi, Ronald J ; Liu, Ruijie ; Huynh, Thanh ; Lee, Se-Jin ; Karch, Jason ; Molkentin, Jeffery D
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-10, Vol.127 (10), p.3770
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van Berlo et al. reply
Author / Creator:van Berlo, Jop H. ; Kanisicak, Onur ; Maillet, Marjorie ; Vagnozzi, Ronald J. ; Karch, Jason ; Lin, Suh-Chin J. ; Middleton, Ryan C. ; Marbán, Eduardo ; Molkentin, Jeffery D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-03, Vol.555 (7697), p.E18-E18
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Kitcre knock-in mice fail to fate-map cardiac stem cells/reply
Author / Creator:Vicinanza, Carla ; Aquila, Iolanda ; Cianflone, Eleonora ; Scalise, Mariangela ; Marino, Fabiola ; Mancuso, Teresa ; Fumagalli, Francesca ; Giovannone, Emilia Dora ; Cristiano, Francesca ; Iaccino, Enrico ; Marotta, Pina ; Torella, Annalaura ; Latini, Roberto ; Agosti, Valter ; Veltri, Pierangelo ; Urbanek, Konrad ; Isidori, Andrea M ; Saur, Dieter ; Indolfi, Ciro ; Nadal-Ginard, Bernardo ; Torella, Daniele ; van Berlo, Jop H ; Kanisicak, Onur ; Maillet, Marjorie ; Vagnozzi, Ronald J ; Karch, Jason ; Lin, Suh-Chin J ; Middleton, Ryan C ; Marbán, Eduardo ; Molkentin, Jeffery D
Publisher:London: Nature Publishing Group
Journal title:Nature (London), 2018-03, Vol.555 (7697), p.E1-E18
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ArticlesPeer ReviewedFull Text
c-[kit.sup.+] cells minimally contribute cardiomyocytes to the heart
Author / Creator:van Berlo, Jop H ; Kanisicak, Onur ; Maillet, Marjorie ; Vagnozzi, Ronald J ; Karch, Jason ; Lin, Suh-Chin J ; Middleton, Ryan C ; Marban, Eduardo ; Molkentin, Jeffery D
Publisher:Nature Publishing Group
Journal title:Nature (London), 2014-05, Vol.509 (7500), p.337
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Showing 1 to 20 of 28 results

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Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions

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Identifying the components of the elusive mitochondrial permeability transition pore

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Genetic lineage tracing defines myofibroblast origin and function in the injured heart

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c-kit+ cells minimally contribute cardiomyocytes to the heart

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Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death

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Misoprostol treatment prevents hypoxia-induced cardiac dysfunction through a 14-3-3 and PKA regulatory motif on Bnip3

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Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak

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Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

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Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability

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A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome

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Phosphorylation-Dependent Interactome of Ryanodine Receptor Type 2 in the Heart

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Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis

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Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

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Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

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Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice

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Irisin: A Promising Target for Ischemia-Reperfusion Injury Therapy

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Fibroblast-specific TGF-[beta]-Smad2/3 signaling underlies cardiac fibrosis

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van Berlo et al. reply

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Kitcre knock-in mice fail to fate-map cardiac stem cells/reply

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c-[kit.sup.+] cells minimally contribute cardiomyocytes to the heart

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