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Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes
Author / Creator:Bakris, George L ; Agarwal, Rajiv ; Anker, Stefan D ; Pitt, Bertram ; Ruilope, Luis M ; Rossing, Peter ; Kolkhof, Peter ; Nowack, Christina ; Schloemer, Patrick ; Joseph, Amer ; Filippatos, Gerasimos
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-12, Vol.383 (23), p.2219-2229
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Direct Blood Pressure-Independent Anti-Fibrotic Effects by the Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone in Progressive Models of Kidney Fibrosis
Author / Creator:Droebner, Karoline ; Pavkovic, Mira ; Grundmann, Manuel ; Hartmann, Elke ; Goea, Laura ; Nordlohne, Johannes ; Klar, Jürgen ; Eitner, Frank ; Kolkhof, Peter
Publisher:Basel, Switzerland: S. Karger AG
Journal title:American journal of nephrology, 2021-09, Vol.52 (7), p.588-601
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Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial
Author / Creator:Bakris, George L. ; Agarwal, Rajiv ; Anker, Stefan D. ; Pitt, Bertram ; Ruilope, Luis M. ; Nowack, Christina ; Kolkhof, Peter ; Ferreira, Anna C. ; Schloemer, Patrick ; Filippatos, Gerasimos
Publisher:Basel, Switzerland: S. Karger AG
Journal title:American journal of nephrology, 2019-11, Vol.50 (5), p.333-344
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Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial
Author / Creator:Ruilope, Luis M. ; Agarwal, Rajiv ; Anker, Stefan D. ; Bakris, George L. ; Filippatos, Gerasimos ; Nowack, Christina ; Kolkhof, Peter ; Joseph, Amer ; Mentenich, Nicole ; Pitt, Bertram
Publisher:Basel, Switzerland: S. Karger AG
Journal title:American journal of nephrology, 2019-11, Vol.50 (5), p.345-356
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The novel mineralocorticoid receptor antagonist finerenone attenuates neointima formation after vascular injury
Author / Creator:Dutzmann, Jochen ; Musmann, Robert-Jonathan ; Haertlé, Marco ; Daniel, Jan-Marcus ; Sonnenschein, Kristina ; Schäfer, Andreas ; Kolkhof, Peter ; Bauersachs, Johann ; Sedding, Daniel G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-09, Vol.12 (9), p.e0184888
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Finerenone Reduces Intrinsic Arterial Stiffness in Munich Wistar Frömter Rats, a Genetic Model of Chronic Kidney Disease
Author / Creator:Gil-Ortega, Marta ; Vega-Martín, Elena ; Martín-Ramos, Miriam ; González-Blázquez, Raquel ; Pulido-Olmo, Helena ; Ruiz-Hurtado, Gema ; Schulz, Angela ; Ruilope, Luis M. ; Kolkhof, Peter ; Somoza, Beatriz ; Kreutz, Reinhold ; Fernández-Alfonso, Maria S.
Publisher:Basel, Switzerland: S. Karger AG
Journal title:American journal of nephrology, 2020-04, Vol.51 (4), p.294-303
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Finerenone cardiovascular and kidney outcomes by age and sex: FIDELITY post hoc analysis of two phase 3, multicentre, double-blind trials
Author / Creator:Bansal, Shweta ; Canziani, Maria E F ; Birne, Rita ; Anker, Stefan D ; Bakris, George L ; Filippatos, Gerasimos ; Rossing, Peter ; Ruilope, Luis M ; Farjat, Alfredo E ; Kolkhof, Peter ; Lage, Andrea ; Brinker, Meike ; Pitt, Bertram
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2024-03, Vol.14 (3), p.e076444
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Suppression of Rapidly Progressive Mouse Glomerulonephritis with the Non-Steroidal Mineralocorticoid Receptor Antagonist BR-4628
Author / Creator:Ma, Frank Y. ; Han, Yingjie ; Nikolic-Paterson, David J. ; Kolkhof, Peter ; Tesch, Greg H.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-12, Vol.10 (12), p.e0145666-e0145666
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New pulmonary hypertension model in conscious dogs to investigate pulmonary-selectivity of acute pharmacological interventions
Author / Creator:Mondritzki, Thomas ; Boehme, Philip ; Schramm, Lena ; Vogel, Julia ; Mathar, Ilka ; Ellinghaus, Peter ; Kolkhof, Peter ; Bischoff, Erwin ; Hüser, Jörg ; Dinh, Wilfried ; Sandner, Peter ; Truebel, Hubert
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European journal of applied physiology, 2018-01, Vol.118 (1), p.195-203
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Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice
Author / Creator:Pieronne‐Deperrois, Marie ; Guéret, Alexandre ; Djerada, Zoubir ; Crochemore, Clément ; Harouki, Najah ; Henry, Jean‐Paul ; Dumesnil, Anaïs ; Larchevêque, Marine ; Rego, Jean‐Claude ; Rego, Jean‐Luc ; Nicol, Lionel ; Richard, Vincent ; Jaisser, Frédéric ; Kolkhof, Peter ; Mulder, Paul ; Monteil, Christelle ; Ouvrard‐Pascaud, Antoine
Publisher:England: John Wiley & Sons, Inc
Journal title:ESC Heart Failure, 2021-06, Vol.8 (3), p.1933-1943
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Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy
Author / Creator:Lowe, Jeovanna ; Kolkhof, Peter ; Haupt, Michael J. ; Peczkowski, Kyra K. ; Rastogi, Neha ; Hauck, J. Spencer ; Kadakia, Feni K. ; Zins, Jonathan G. ; Ciccone, Pierce C. ; Smart, Suzanne ; Sandner, Peter ; Raman, Subha V. ; Janssen, Paul M.L. ; Rafael‐Fortney, Jill A.
Publisher:England: John Wiley & Sons, Inc
Journal title:ESC Heart Failure, 2020-12, Vol.7 (6), p.3983-3995
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Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes
Author / Creator:Pitt, Bertram ; Filippatos, Gerasimos ; Agarwal, Rajiv ; Anker, Stefan D ; Bakris, George L ; Rossing, Peter ; Joseph, Amer ; Kolkhof, Peter ; Nowack, Christina ; Schloemer, Patrick ; Ruilope, Luis M
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2021-12, Vol.385 (24), p.2252-2263
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Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage
Author / Creator:Kolkhof, Peter ; Hartmann, Elke ; Freyberger, Alexius ; Pavkovic, Mira ; Mathar, Ilka ; Sandner, Peter ; Droebner, Karoline ; Joseph, Amer ; Hüser, Jörg ; Eitner, Frank
Publisher:Basel, Switzerland: S. Karger AG
Journal title:American journal of nephrology, 2021-10, Vol.52 (8), p.642-652
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Nonsteroidal Mineralocorticoid Receptor Antagonism by Finerenone—Translational Aspects and Clinical Perspectives across Multiple Organ Systems
Author / Creator:Kolkhof, Peter ; Lawatscheck, Robert ; Filippatos, Gerasimos ; Bakris, George L.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-08, Vol.23 (16), p.9243
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Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction
Author / Creator:Solomon, Scott D. ; McMurray, John J.V. ; Vaduganathan, Muthiah ; Claggett, Brian ; Jhund, Pardeep S. ; Desai, Akshay S. ; Henderson, Alasdair D. ; Lam, Carolyn S.P. ; Pitt, Bertram ; Senni, Michele ; Shah, Sanjiv J. ; Voors, Adriaan A. ; Zannad, Faiez ; Abidin, Imran Zainal ; Alcocer-Gamba, Marco Antonio ; Atherton, John J. ; Bauersachs, Johann ; Chang-Sheng, Ma ; Chiang, Chern-En ; Chioncel, Ovidiu ; Chopra, Vijay ; Comin-Colet, Josep ; Filippatos, Gerasimos ; Fonseca, Cândida ; Gajos, Grzegorz ; Goland, Sorel ; Goncalvesova, Eva ; Kang, Seokmin ; Katova, Tzvetana ; Kosiborod, Mikhail N. ; Latkovskis, Gustavs ; Lee, Alex Pui-Wai ; Linssen, Gerard C.M. ; Llamas-Esperón, Guillermo ; Mareev, Vyacheslav ; Martinez, Felipe A. ; Melenovský, Vojtěch ; Merkely, Béla ; Nodari, Savina ; Petrie, Mark C. ; Saldarriaga, Clara Inés ; Saraiva, Jose Francisco Kerr ; Sato, Naoki ; Schou, Morten ; Sharma, Kavita ; Troughton, Richard ; Udell, Jacob A. ; Ukkonen, Heikki ; Vardeny, Orly ; Verma, Subodh ; von Lewinski, Dirk ; Voronkov, Leonid ; Yilmaz, Mehmet Birhan ; Zieroth, Shelley ; Lay-Flurrie, James ; van Gameren, Ilse ; Amarante, Flaviana ; Kolkhof, Peter ; Viswanathan, Prabhakar
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-10, Vol.391 (16), p.1475-1485
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Comments on: Lyubarova, R. and Gosmanova, E.O. Mineralocorticoid Receptor Blockade in End-Stage Renal Disease. Current Hypertension Reports, 2017. 19(5)
Author / Creator:Gay, Alain ; Kolkhof, Peter
Publisher:New York: Springer US
Journal title:Current hypertension reports, 2017-09, Vol.19 (9), p.74-74, Article 74
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A randomized controlled study of finerenone versus placebo in Japanese patients with type 2 diabetes mellitus and diabetic nephropathy
Author / Creator:Katayama, Shigehiro ; Yamada, Daishiro ; Nakayama, Mikihiro ; Yamada, Takashi ; Myoishi, Masafumi ; Kato, Masaharu ; Nowack, Christina ; Kolkhof, Peter ; Yamasaki, Yoshimitsu
Publisher:United States: Elsevier Inc
Journal title:Journal of diabetes and its complications, 2017-04, Vol.31 (4), p.758-765
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Benefits of the Non-Steroidal Mineralocorticoid Receptor Antagonist Finerenone in Metabolic Syndrome-Related Heart Failure with Preserved Ejection Fraction
Author / Creator:Lima-Posada, Ixchel ; Stephan, Yohan ; Soulié, Matthieu ; Palacios-Ramirez, Roberto ; Bonnard, Benjamin ; Nicol, Lionel ; Kolkhof, Peter ; Jaisser, Frederic ; Mulder, Paul
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-02, Vol.24 (3), p.2536
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Population Pharmacokinetic and Exposure–Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic K...
Author / Creator:Snelder, Nelleke ; Heinig, Roland ; Drenth, Henk-Jan ; Joseph, Amer ; Kolkhof, Peter ; Lippert, Jörg ; Garmann, Dirk ; Ploeger, Bart ; Eissing, Thomas
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2020-03, Vol.59 (3), p.359-370
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Finerenone, a Non-Steroidal Mineralocorticoid Receptor Antagonist, Reduces Vascular Injury and Increases Regulatory T-Cells: Studies in Rodents with Diabetic and Neovascular Retinopathy
Author / Creator:Jerome, Jack R. ; Deliyanti, Devy ; Suphapimol, Varaporn ; Kolkhof, Peter ; Wilkinson-Berka, Jennifer L.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-01, Vol.24 (3), p.2334
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Showing 1 to 20 of 30 results

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Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes

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Direct Blood Pressure-Independent Anti-Fibrotic Effects by the Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone in Progressive Models of Kidney Fibrosis

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Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial

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Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial

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The novel mineralocorticoid receptor antagonist finerenone attenuates neointima formation after vascular injury

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Finerenone Reduces Intrinsic Arterial Stiffness in Munich Wistar Frömter Rats, a Genetic Model of Chronic Kidney Disease

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Finerenone cardiovascular and kidney outcomes by age and sex: FIDELITY post hoc analysis of two phase 3, multicentre, double-blind trials

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Suppression of Rapidly Progressive Mouse Glomerulonephritis with the Non-Steroidal Mineralocorticoid Receptor Antagonist BR-4628

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New pulmonary hypertension model in conscious dogs to investigate pulmonary-selectivity of acute pharmacological interventions

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Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice

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Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy

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Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes

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Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage

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Nonsteroidal Mineralocorticoid Receptor Antagonism by Finerenone—Translational Aspects and Clinical Perspectives across Multiple Organ Systems

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Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction

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Comments on: Lyubarova, R. and Gosmanova, E.O. Mineralocorticoid Receptor Blockade in End-Stage Renal Disease. Current Hypertension Reports, 2017. 19(5)

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A randomized controlled study of finerenone versus placebo in Japanese patients with type 2 diabetes mellitus and diabetic nephropathy

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Benefits of the Non-Steroidal Mineralocorticoid Receptor Antagonist Finerenone in Metabolic Syndrome-Related Heart Failure with Preserved Ejection Fraction

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Population Pharmacokinetic and Exposure–Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic K...

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Finerenone, a Non-Steroidal Mineralocorticoid Receptor Antagonist, Reduces Vascular Injury and Increases Regulatory T-Cells: Studies in Rodents with Diabetic and Neovascular Retinopathy

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