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Sketches and hints on landscape gardening : collected from designs and observations now in the possession of the different noblemen and gentlemen, for whose use they were originally made. The whole tending to establish fixed principles in the art of laying out ground / by H. Repton.

Box 62: Subject and place file, Sydney, N.S.W. – The Rocks – Streets - Cumberland Street to Sydney, N.S.W. – Shops – Sydney Morning Herald, ca. 1842 to 1972

The Oxford handbook of memory / edited by Endel Tulving, Fergus I.M. Craik.

Introduction
Dozens of Alzheimer's disease (AD)‐associated loci have been identified in European‐descent populations, but their effects have not been thoroughly investigated in the Hong Kong Chinese population.
Methods
TaqMan array genotyping was performed for known AD‐associated variants in a Hong Kong Chinese cohort. Regression analysis was conducted to study the associations of variants with AD‐associated traits and biomarkers. Lasso regression was applied to establish a polygenic risk score (PRS) model for AD risk prediction.
Results
SORL1 is associated with AD in the Hong Kong Chinese population. Meta‐analysis corroborates the AD‐protective effect of the SORL1 rs11218343 C allele. The PRS is developed and associated with AD risk, cognitive status, and AD‐related endophenotypes. TREM2 H157Y might influence the amyloid beta 42/40 ratio and levels of immune‐associated proteins in plasma.
Discussion
SORL1 is associated with AD in the Hong Kong Chinese population. The PRS model can predict AD risk and cognitive status in this population.

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2020, Vol.12 (1), p.e12074-n/a

Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population

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Sketches and hints on landscape gardening : collected from designs and observations now in the possession of the different noblemen and gentlemen, for whose use they were originally made. The whole te...

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Export record to excel

Box 62: Subject and place file, Sydney, N.S.W. – The Rocks – Streets - Cumberland Street to Sydney, N.S.W. – Shops – Sydney Morning Herald, ca. 1842 to 1972

Export this record

Export record to excel

The Oxford handbook of memory / edited by Endel Tulving, Fergus I.M. Craik.

Export this record

Export record to excel

Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population

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